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Protein

Ribonucleases P/MRP protein subunit POP5

Gene

SPCC830.09c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP, which cleaves pre-rRNA sequences (By similarity).By similarity

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.

GO - Molecular functioni

  1. ribonuclease P activity Source: UniProtKB-EC

GO - Biological processi

  1. RNA phosphodiester bond hydrolysis Source: GOC
  2. RNA phosphodiester bond hydrolysis, endonucleolytic Source: GOC
  3. rRNA processing Source: PomBase
  4. tRNA processing Source: PomBase
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

tRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonucleases P/MRP protein subunit POP5 (EC:3.1.26.5)
Gene namesi
ORF Names:SPCC830.09c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
ProteomesiUP000002485 Componenti: Chromosome III

Organism-specific databases

PomBaseiSPCC830.09c.

Subcellular locationi

Nucleus Curated

GO - Cellular componenti

  1. endoplasmic reticulum Source: PomBase
  2. nucleolar ribonuclease P complex Source: PomBase
  3. ribonuclease MRP complex Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 139139Ribonucleases P/MRP protein subunit POP5PRO_0000140014Add
BLAST

Proteomic databases

MaxQBiQ9UU90.

Interactioni

Protein-protein interaction databases

MINTiMINT-4711414.
STRINGi4896.SPCC830.09c-1.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1369.
HOGENOMiHOG000216538.
InParanoidiQ9UU90.
KOiK03537.
OMAiLECDEAK.
OrthoDBiEOG7M6DM5.
PhylomeDBiQ9UU90.

Family and domain databases

HAMAPiMF_00755. RNase_P_2.
InterProiIPR016819. RNase_P/MRP_POP5.
IPR002759. RNase_P/MRP_subunit.
[Graphical view]
PfamiPF01900. RNase_P_Rpp14. 1 hit.
[Graphical view]
PIRSFiPIRSF023803. Ribonuclease_P_prd. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9UU90-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRFKSRYLL FEVLYPEAKE FFDYPTIPSD SSITTSSLSK IIRTMVAENF
60 70 80 90 100
GDVGIGKVAS SLTVKYFSPN TSTGILRVSR QHFRLAWAAL VLIRELYGKP
110 120 130
VIIRVVRVSG TIKKAELAAI ERNKSEIHNI SLMDEPIEV
Length:139
Mass (Da):15,680
Last modified:April 30, 2000 - v1
Checksum:i3E581179B769E589
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAB52882.1.
PIRiT41635.
RefSeqiNP_588479.1. NM_001023470.2.

Genome annotation databases

EnsemblFungiiSPCC830.09c.1; SPCC830.09c.1:pep; SPCC830.09c.
GeneIDi2538895.
KEGGispo:SPCC830.09c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAB52882.1.
PIRiT41635.
RefSeqiNP_588479.1. NM_001023470.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-4711414.
STRINGi4896.SPCC830.09c-1.

Proteomic databases

MaxQBiQ9UU90.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPCC830.09c.1; SPCC830.09c.1:pep; SPCC830.09c.
GeneIDi2538895.
KEGGispo:SPCC830.09c.

Organism-specific databases

PomBaseiSPCC830.09c.

Phylogenomic databases

eggNOGiCOG1369.
HOGENOMiHOG000216538.
InParanoidiQ9UU90.
KOiK03537.
OMAiLECDEAK.
OrthoDBiEOG7M6DM5.
PhylomeDBiQ9UU90.

Miscellaneous databases

NextBioi20800074.
PROiQ9UU90.

Family and domain databases

HAMAPiMF_00755. RNase_P_2.
InterProiIPR016819. RNase_P/MRP_POP5.
IPR002759. RNase_P/MRP_subunit.
[Graphical view]
PfamiPF01900. RNase_P_Rpp14. 1 hit.
[Graphical view]
PIRSFiPIRSF023803. Ribonuclease_P_prd. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.

Entry informationi

Entry nameiPOP5_SCHPO
AccessioniPrimary (citable) accession number: Q9UU90
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 28, 2004
Last sequence update: April 30, 2000
Last modified: March 31, 2015
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.