Reviewed,
UniProtKB/Swiss-Prot Q9UTN8 (UBC14_SCHPO)
Last modified
January 19, 2010.
Version 56.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
Third-party data |
Customize display | text xml rdf/xml gff fasta |
Names and origin
| Protein names | Recommended name: Ubiquitin-conjugating enzyme E2 14 EC=6.3.2.19 Alternative name(s): Ubiquitin-protein ligase 14 Ubiquitin carrier protein 14 | ||||
| Gene names |
| ||||
| Organism | Schizosaccharomyces pombe (Fission yeast) [Complete proteome] | ||||
| Taxonomic identifier | 4896 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces |
Protein attributes
| Sequence length | 155 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Function | Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins By similarity. UniProtKB P15731 |
| Catalytic activity | ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine. UniProtKB P15731 |
| Pathway | Protein modification; protein ubiquitination. UniProtKB P15731 |
| Sequence similarities | Belongs to the ubiquitin-conjugating enzyme family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Ubl conjugation pathway |
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Ligase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | modification-dependent protein catabolic process Inferred from electronic annotation. Source: UniProtKB-KW protein ubiquitinationInferred by curator. Source: GeneDB_SPombe regulation of protein metabolic processInferred from electronic annotation. Source: InterPro |
| Molecular function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ubiquitin-protein ligase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 155 | 155 | Ubiquitin-conjugating enzyme E2 14 | PRO_0000361053 | |||||
Sites | |||||||||
| Active site | 91 | 1 | Glycyl thioester intermediate By similarity UniProtKB P15731 | ||||||
Sequences
| ||||||||||||||||||
References
| [1] | "The genome sequence of Schizosaccharomyces pombe." Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. Nurse P.Nature 415:871-880(2002) [PubMed: 11859360] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 38366 / 972. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CU329670 Genomic DNA. Translation: CAB54826.1. |
| PIR | T37559. |
| RefSeq | NP_594859.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1QCQ based on UniProtKB P15731. |
| SMR | Q9UTN8. Positions 4-155. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 2541565. |
| GenomeReviews | Gene locus ubc14 in contig CU329670_GR. |
| KEGG | spo:SPAC1250.03. |
| NMPDR | fig|4896.1.peg.4829. |
Organism-specific databases | |
| GeneDB_Spombe | SPAC1250.03. |
Phylogenomic databases | |
| eggNOG | fuNOG11181. |
| HOGENOM | HBG756483. |
| OMA | AGNICIS. |
| OrthoDB | EOG9TQNSM. |
| PhylomeDB | Q9UTN8. |
Gene expression databases | |
| ArrayExpress | Q9UTN8. |
Family and domain databases | |
| InterPro | IPR016135. UBQ-conjugat/RWD-like. IPR000608. UBQ-conjugat_E2. [Graphical view] |
| Gene3D | G3DSA:3.10.110.10. UBQ-conjugat_E2. 1 hit. |
| Pfam | PF00179. UQ_con. 1 hit. [Graphical view] |
| SMART | SM00212. UBCc. 1 hit. [Graphical view] |
| PROSITE | PS00183. UBIQUITIN_CONJUGAT_1. False negative. PS50127. UBIQUITIN_CONJUGAT_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | UBC14_SCHPO | ||||||||
| Accession | Primary (citable) accession number: Q9UTN8 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| Schizosaccharomyces pombe Schizosaccharomyces pombe: entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with


