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Protein

J-type co-chaperone jac1, mitochondrial

Gene

jac1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Co-chaperone required for the assembly of iron-sulfur (Fe/S) clusters in mitochondria. Stimulates the ATPase activity of the mitochondrial Hsp70 chaperone (mtHsp70). Binds to the substrate protein isu1 and targets it to mtHsp70 (By similarity).By similarity

GO - Molecular functioni

  • ATPase activator activity Source: PomBase
  • Hsp70 protein binding Source: PomBase

GO - Biological processi

Keywordsi

Molecular functionChaperone

Names & Taxonomyi

Protein namesi
Recommended name:
J-type co-chaperone jac1, mitochondrial
Alternative name(s):
J-type accessory chaperone 1
Gene namesi
Name:jac1
ORF Names:SPAC144.08
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC144.08.
PomBaseiSPAC144.08. jac1.

Subcellular locationi

GO - Cellular componenti

  • mitochondrial matrix Source: UniProtKB-SubCell
  • mitochondrion Source: PomBase

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 49MitochondrionSequence analysisAdd BLAST49
ChainiPRO_000036338850 – 225J-type co-chaperone jac1, mitochondrialAdd BLAST176

Proteomic databases

MaxQBiQ9UTL6.
PRIDEiQ9UTL6.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

MINTiMINT-4710761.

Structurei

3D structure databases

ProteinModelPortaliQ9UTL6.
SMRiQ9UTL6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini61 – 137JAdd BLAST77

Sequence similaritiesi

Belongs to the HscB family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

InParanoidiQ9UTL6.
OMAiNENYEDA.
OrthoDBiEOG092C4Z2R.
PhylomeDBiQ9UTL6.

Family and domain databases

CDDicd06257. DnaJ. 1 hit.
Gene3Di1.10.287.110. 1 hit.
1.20.1280.20. 1 hit.
InterProiView protein in InterPro
IPR001623. DnaJ_domain.
IPR004640. HscB.
IPR009073. HscB_oligo_C.
PANTHERiPTHR14021. PTHR14021. 1 hit.
PfamiView protein in Pfam
PF07743. HSCB_C. 1 hit.
SUPFAMiSSF46565. SSF46565. 1 hit.
SSF47144. SSF47144. 1 hit.
TIGRFAMsiTIGR00714. hscB. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9UTL6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKQAGNQSF RPFISFAQKS LFNRQITGNH WIFARFKFYP LNKIVNYNHF
60 70 80 90 100
HSSSCQSEAK NFYKQFEGDI SDPPPKGPFD IDLGALKSSY LRKMKTLHPD
110 120 130 140 150
VAQGKDAALA QRDSAELSKA YNTLKAPLTR AEYILQLQGI NPVSEDISNS
160 170 180 190 200
DPEFLMEIMD VHENISASRD SPEKLLQLSQ ENQGRKVQEI NEIRKAMESS
210 220
NWDSALLYVN RLRYWNTIDK ILHDL
Length:225
Mass (Da):25,901
Last modified:May 1, 2000 - v1
Checksum:i41F3DB1FBED9C466
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB59688.1.
PIRiT37675.
RefSeqiNP_594669.1. NM_001020098.2.

Genome annotation databases

EnsemblFungiiSPAC144.08.1; SPAC144.08.1:pep; SPAC144.08.
GeneIDi2542900.
KEGGispo:SPAC144.08.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB59688.1.
PIRiT37675.
RefSeqiNP_594669.1. NM_001020098.2.

3D structure databases

ProteinModelPortaliQ9UTL6.
SMRiQ9UTL6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-4710761.

Proteomic databases

MaxQBiQ9UTL6.
PRIDEiQ9UTL6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC144.08.1; SPAC144.08.1:pep; SPAC144.08.
GeneIDi2542900.
KEGGispo:SPAC144.08.

Organism-specific databases

EuPathDBiFungiDB:SPAC144.08.
PomBaseiSPAC144.08. jac1.

Phylogenomic databases

InParanoidiQ9UTL6.
OMAiNENYEDA.
OrthoDBiEOG092C4Z2R.
PhylomeDBiQ9UTL6.

Miscellaneous databases

PROiQ9UTL6.

Family and domain databases

CDDicd06257. DnaJ. 1 hit.
Gene3Di1.10.287.110. 1 hit.
1.20.1280.20. 1 hit.
InterProiView protein in InterPro
IPR001623. DnaJ_domain.
IPR004640. HscB.
IPR009073. HscB_oligo_C.
PANTHERiPTHR14021. PTHR14021. 1 hit.
PfamiView protein in Pfam
PF07743. HSCB_C. 1 hit.
SUPFAMiSSF46565. SSF46565. 1 hit.
SSF47144. SSF47144. 1 hit.
TIGRFAMsiTIGR00714. hscB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiJAC1_SCHPO
AccessioniPrimary (citable) accession number: Q9UTL6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: May 1, 2000
Last modified: March 15, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.