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Reviewed, UniProtKB/Swiss-Prot Q9UTK3 (NPT1_SCHPO)

Last modified February 9, 2010. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Probable nicotinate phosphoribosyltransferase
      Short name=NAPRTase
    EC=2.4.2.11
Gene names
ORF Names: SPAC1486.06
OrganismSchizosaccharomyces pombe (Fission yeast) [Complete proteome]
Taxonomic identifier4896 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces

Protein attributes

Sequence length410 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level.

General annotation (Comments)

Catalytic activity

Nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate.

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1.

Sequence similarities

Belongs to the NAPRTase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 410410Probable nicotinate phosphoribosyltransferase
PRO_0000205861

Sequences

Sequence LengthMass (Da)Tools
Q9UTK3-1 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: E4230ADD9ABA6077

FASTA41046,694
        10         20         30         40         50         60 
MSEPAVVSIL DTDLYKLTML QAVLEHYPDA QVSYKYTNRS PKMALNQEAY NWLREQIRGL 

        70         80         90        100        110        120 
RNLHLLPEEE QWLRKNCPYL KESFYEFMHE FEFDPENSIS LNYDSETKDL SIFIHGLWKN 

       130        140        150        160        170        180 
TIFYEIPLLA LVSESYFKFV DKDWSPEGQF EKAYEKGKRL IRAGCAFTDF GTRRRRDPHT 

       190        200        210        220        230        240 
QEIVLQGLMK AQEDFKGPGS FLGTSNVYFA AKYNLNVSGT VAHEWYMGIA AITQNYKQAN 

       250        260        270        280        290        300 
RIASLKWVQT FGTSLLIALT DTFSTDVFLK SFTANSADDL ANVFHGVRQD SGCAEEYIEK 

       310        320        330        340        350        360 
VVKHYKSIGV DPSTKVIVHS DALNVDRCIE LYKYCEKCGI KSAFGIGTNL TSDFQKVSNP 

       370        380        390        400        410 
SEVSKPMNIV IKLFSAEGTK AVKISDDIMK NTGDRDAVIQ AKHQLCLPIA 

« Hide

References

[1]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed: 11859360] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 38366 / 972.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU329670 Genomic DNA. Translation: CAB62416.1.
PIRT50075.
RefSeqNP_594094.1.

3D structure databases

SMRQ9UTK3. Positions 1-405.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ9UTK3.

Genome annotation databases

GeneID2542272.
KEGGspo:SPAC1486.06.
NMPDRfig|4896.1.peg.4064.

Organism-specific databases

GeneDB_SpombeSPAC1486.06.

Phylogenomic databases

eggNOGfuNOG05269.
HOGENOMHBG325503.
OMALYKFTML.
OrthoDBEOG93XWKM.
PhylomeDBQ9UTK3.

Enzyme and pathway databases

BRENDA2.4.2.11. 653.

Gene expression databases

ArrayExpressQ9UTK3.

Family and domain databases

InterProIPR006406. Nic_PRibTrfase.
IPR015977. Nic_PRibTrfase-like.
IPR007229. Nic_PRibTrfase-rel.
[Graphical view]
PANTHERPTHR11098:SF1. NAPRTase. 1 hit.
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameNPT1_SCHPO
AccessionPrimary (citable) accession number: Q9UTK3
Entry history
Integrated into UniProtKB/Swiss-Prot: July 11, 2002
Last sequence update: May 1, 2000
Last modified: February 9, 2010
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents