Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable ethanolamine-phosphate cytidylyltransferase

Gene

SPAC15E1.05c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

CTP + ethanolamine phosphate = diphosphate + CDP-ethanolamine.

Pathwayi: phosphatidylethanolamine biosynthesis

This protein is involved in step 2 of the subpathway that synthesizes phosphatidylethanolamine from ethanolamine.
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Probable ethanolamine-phosphate cytidylyltransferase (SPAC15E1.05c)
  3. no protein annotated in this organism
This subpathway is part of the pathway phosphatidylethanolamine biosynthesis, which is itself part of Phospholipid metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes phosphatidylethanolamine from ethanolamine, the pathway phosphatidylethanolamine biosynthesis and in Phospholipid metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferase, Transferase
Biological processLipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

Enzyme and pathway databases

UniPathwayiUPA00558; UER00742

Names & Taxonomyi

Protein namesi
Recommended name:
Probable ethanolamine-phosphate cytidylyltransferase (EC:2.7.7.14)
Alternative name(s):
CTP:phosphoethanolamine cytidylyltransferase
Phosphorylethanolamine transferase
Gene namesi
ORF Names:SPAC15E1.05c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC15E1.05c
PomBaseiSPAC15E1.05c

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002084641 – 365Probable ethanolamine-phosphate cytidylyltransferaseAdd BLAST365

Proteomic databases

MaxQBiQ9UTI6
PaxDbiQ9UTI6
PRIDEiQ9UTI6

Interactioni

Protein-protein interaction databases

BioGridi279224, 2 interactors
STRINGi4896.SPAC15E1.05c.1

Structurei

3D structure databases

ProteinModelPortaliQ9UTI6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytidylyltransferase family.Curated

Phylogenomic databases

HOGENOMiHOG000187618
InParanoidiQ9UTI6
KOiK00967
OMAiCHGKTEI
OrthoDBiEOG092C3LI1
PhylomeDBiQ9UTI6

Family and domain databases

Gene3Di3.40.50.620, 2 hits
InterProiView protein in InterPro
IPR004821 Cyt_trans-like
IPR014729 Rossmann-like_a/b/a_fold
PfamiView protein in Pfam
PF01467 CTP_transf_like, 1 hit
TIGRFAMsiTIGR00125 cyt_tran_rel, 1 hit

Sequencei

Sequence statusi: Complete.

Q9UTI6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASSSNIKHR LWLDGCMDFF HYGHSNAILQ AKQLGETLVI GIHSDEEITL
60 70 80 90 100
NKGPPVMTLE ERCLSANTCK WVDEVVPSAP YVFDLEWMRR YGCQYVVHGD
110 120 130 140 150
DISTDANGDD CYRFAKAADQ YLEVKRTEGV STTELLDRLL SSVPLEIYST
160 170 180 190 200
PVSVLSSQID LLRRFATDSD GLTPFTDVFI YNTEKPETLI SGTTLLRLNP
210 220 230 240 250
EKNIIYIDGD WDLFTEKHIS ALELCTRMFP GIPIMAGIFA DEKCFEKPML
260 270 280 290 300
NLLERILNLL QCKYISSILV GPPPASLFAS SKYIKLCFDE QISKVYYPIF
310 320 330 340 350
STDVSIPALD ISLSNTPNNS FYKFDKLGSD LIKQRVMLRR QHYEERQRRK
360
MGKNATEQTT IKTYA
Length:365
Mass (Da):41,557
Last modified:May 1, 2000 - v1
Checksum:iACDB6A974ABB4734
GO

Sequence cautioni

The sequence BAA13860 differs from that shown. Reason: Frameshift at position 47.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti63C → G in BAA13860 (PubMed:9501991).Curated1
Sequence conflicti268I → L in BAA13860 (PubMed:9501991).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAB52424.1
D89199 mRNA Translation: BAA13860.1 Frameshift.
PIRiT37720
T42999
RefSeqiNP_594306.1, NM_001019729.2

Genome annotation databases

EnsemblFungiiSPAC15E1.05c.1; SPAC15E1.05c.1:pep; SPAC15E1.05c
KEGGispo:SPAC15E1.05c

Similar proteinsi

Entry informationi

Entry nameiECT1_SCHPO
AccessioniPrimary (citable) accession number: Q9UTI6
Secondary accession number(s): P78849
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 24, 2001
Last sequence update: May 1, 2000
Last modified: May 23, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health