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Protein

Probable lysophospholipase C1786.02

Gene

SPAC1786.02

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the release of fatty acids from lysophospholipids.By similarity

Catalytic activityi

2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processLipid degradation, Lipid metabolism

Names & Taxonomyi

Protein namesi
Recommended name:
Probable lysophospholipase C1786.02 (EC:3.1.1.5)
Alternative name(s):
Phospholipase B
Gene namesi
ORF Names:SPAC1786.02
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC1786.02.
PomBaseiSPAC1786.02.

Subcellular locationi

GO - Cellular componenti

  • anchored component of external side of plasma membrane Source: PomBase
  • endoplasmic reticulum Source: PomBase
  • extracellular region Source: UniProtKB-SubCell
  • fungal-type cell wall Source: PomBase

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_000002464420 – 644Probable lysophospholipase C1786.02Add BLAST625

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi44N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi96N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi141N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi178N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi221N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi245N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi253N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi281N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi286N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi316N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi319N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi373N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi393N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi449N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi501N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi558N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi579N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi596N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQBiQ9UTH5.
PRIDEiQ9UTH5.

Interactioni

Protein-protein interaction databases

BioGridi278640. 1 interactor.
MINTiMINT-4710476.

Structurei

3D structure databases

ProteinModelPortaliQ9UTH5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini53 – 600PLA2cPROSITE-ProRule annotationAdd BLAST548

Sequence similaritiesi

Belongs to the lysophospholipase family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000189547.
InParanoidiQ9UTH5.
KOiK13333.
OMAiVHANILL.
OrthoDBiEOG092C2IZ9.
PhylomeDBiQ9UTH5.

Family and domain databases

InterProiView protein in InterPro
IPR016035. Acyl_Trfase/lysoPLipase.
IPR002642. LysoPLipase_cat_dom.
PfamiView protein in Pfam
PF01735. PLA2_B. 1 hit.
SMARTiView protein in SMART
SM00022. PLAc. 1 hit.
SUPFAMiSSF52151. SSF52151. 1 hit.
PROSITEiView protein in PROSITE
PS51210. PLA2C. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9UTH5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYFQSFYFLA LLLATAVYGQ VASPELHSLS RRNWKKPPPF PSTNASYAPV
60 70 80 90 100
IRSCDSSEIM VNSLPRGELP DLENDFIEKR LSNANEALTT FLQSKNTTAD
110 120 130 140 150
LDLSSIVGDN GPRLGIAVSG GGWRSMLFGG GALAALDSRS NETTLGGLLQ
160 170 180 190 200
SAHYITGADG GSWLLSSLAV NEFRTIQNIS KSIWYTRLGI FFIEETHFGD
210 220 230 240 250
LKNYYTNVVD EVNQKAAAGF NVSLTDYWGR AIARHFVGQL RGGPNLTYSS
260 270 280 290 300
VQNASWFQTA EYPYPLIVTQ GLTGGLPDGS NGTATNSSIY EISPYYLTSF
310 320 330 340 350
DNNVRSYTPT QYLGTNYSNG TAVDGKCVTQ FDNVGFLVGT SSTRYNEALI
360 370 380 390 400
DVSLRQSRMS RRLGFTLRHM RINGSSVSFY PNPYTDATDI AGNATAVSED
410 420 430 440 450
IVDTPYLDLF DGGYDGQNIP IWPLLQPERK LDVVFAFDSS GDTSNFWPNG
460 470 480 490 500
SSLVATYERV TQRASDAVYD VEDFVHVPTP ETFVNLGLNA NPTFFGCDGR
510 520 530 540 550
NTTRGDVPVD HNTPPLVVYM PNTPWTMKSN LVDHRYRIAN SEIQALIQNG
560 570 580 590 600
FVATTQDNST DFASCLACAV VQRSLERRNQ STSAACQQCF SQYCWNGTVD
610 620 630 640
NTPVDDDSKN PTYNPAVKTS SASGVHANIL LSFFVLLATL LVTA
Length:644
Mass (Da):70,570
Last modified:May 1, 2000 - v1
Checksum:iEB42D2427EA804D1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB57433.1.
AB027917 Genomic DNA. Translation: BAA87221.1.
PIRiT37800.
RefSeqiNP_594024.1. NM_001019449.2.

Genome annotation databases

EnsemblFungiiSPAC1786.02.1; SPAC1786.02.1:pep; SPAC1786.02.
GeneIDi2542164.
KEGGispo:SPAC1786.02.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB57433.1.
AB027917 Genomic DNA. Translation: BAA87221.1.
PIRiT37800.
RefSeqiNP_594024.1. NM_001019449.2.

3D structure databases

ProteinModelPortaliQ9UTH5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi278640. 1 interactor.
MINTiMINT-4710476.

Proteomic databases

MaxQBiQ9UTH5.
PRIDEiQ9UTH5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC1786.02.1; SPAC1786.02.1:pep; SPAC1786.02.
GeneIDi2542164.
KEGGispo:SPAC1786.02.

Organism-specific databases

EuPathDBiFungiDB:SPAC1786.02.
PomBaseiSPAC1786.02.

Phylogenomic databases

HOGENOMiHOG000189547.
InParanoidiQ9UTH5.
KOiK13333.
OMAiVHANILL.
OrthoDBiEOG092C2IZ9.
PhylomeDBiQ9UTH5.

Miscellaneous databases

PROiPR:Q9UTH5.

Family and domain databases

InterProiView protein in InterPro
IPR016035. Acyl_Trfase/lysoPLipase.
IPR002642. LysoPLipase_cat_dom.
PfamiView protein in Pfam
PF01735. PLA2_B. 1 hit.
SMARTiView protein in SMART
SM00022. PLAc. 1 hit.
SUPFAMiSSF52151. SSF52151. 1 hit.
PROSITEiView protein in PROSITE
PS51210. PLA2C. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPLB6_SCHPO
AccessioniPrimary (citable) accession number: Q9UTH5
Secondary accession number(s): Q9UTZ2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 23, 2003
Last sequence update: May 1, 2000
Last modified: May 10, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.