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Q9UTH5

- PLB6_SCHPO

UniProt

Q9UTH5 - PLB6_SCHPO

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Protein
Probable lysophospholipase C1786.02
Gene
SPAC1786.02
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the release of fatty acids from lysophospholipids By similarity.

Catalytic activityi

2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.

GO - Molecular functioni

  1. lysophospholipase activity Source: UniProtKB-EC
  2. phospholipase activity Source: PomBase

GO - Biological processi

  1. glycerophospholipid catabolic process Source: PomBase
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Lipid degradation, Lipid metabolism

Names & Taxonomyi

Protein namesi
Recommended name:
Probable lysophospholipase C1786.02 (EC:3.1.1.5)
Alternative name(s):
Phospholipase B
Gene namesi
ORF Names:SPAC1786.02
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
ProteomesiUP000002485: Chromosome I

Organism-specific databases

PomBaseiSPAC1786.02.

Subcellular locationi

Secreted Inferred

GO - Cellular componenti

  1. anchored component of external side of plasma membrane Source: PomBase
  2. endoplasmic reticulum Source: PomBase
  3. extracellular region Source: UniProtKB-SubCell
  4. fungal-type cell wall Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919 Reviewed prediction
Add
BLAST
Chaini20 – 644625Probable lysophospholipase C1786.02
PRO_0000024644Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi44 – 441N-linked (GlcNAc...) Reviewed prediction
Glycosylationi96 – 961N-linked (GlcNAc...) Reviewed prediction
Glycosylationi141 – 1411N-linked (GlcNAc...) Reviewed prediction
Glycosylationi178 – 1781N-linked (GlcNAc...) Reviewed prediction
Glycosylationi221 – 2211N-linked (GlcNAc...) Reviewed prediction
Glycosylationi245 – 2451N-linked (GlcNAc...) Reviewed prediction
Glycosylationi253 – 2531N-linked (GlcNAc...) Reviewed prediction
Glycosylationi281 – 2811N-linked (GlcNAc...) Reviewed prediction
Glycosylationi286 – 2861N-linked (GlcNAc...) Reviewed prediction
Glycosylationi316 – 3161N-linked (GlcNAc...) Reviewed prediction
Glycosylationi319 – 3191N-linked (GlcNAc...) Reviewed prediction
Glycosylationi373 – 3731N-linked (GlcNAc...) Reviewed prediction
Glycosylationi393 – 3931N-linked (GlcNAc...) Reviewed prediction
Glycosylationi449 – 4491N-linked (GlcNAc...) Reviewed prediction
Glycosylationi501 – 5011N-linked (GlcNAc...) Reviewed prediction
Glycosylationi558 – 5581N-linked (GlcNAc...) Reviewed prediction
Glycosylationi579 – 5791N-linked (GlcNAc...) Reviewed prediction
Glycosylationi596 – 5961N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQBiQ9UTH5.
PaxDbiQ9UTH5.

Interactioni

Protein-protein interaction databases

BioGridi278640. 3 interactions.
MINTiMINT-4710476.
STRINGi4896.SPAC1786.02-1.

Structurei

3D structure databases

ProteinModelPortaliQ9UTH5.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini53 – 600548PLA2c
Add
BLAST

Sequence similaritiesi

Belongs to the lysophospholipase family.
Contains 1 PLA2c domain.

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG290086.
HOGENOMiHOG000189547.
KOiK13333.
OMAiVHANILL.
OrthoDBiEOG7N37NC.
PhylomeDBiQ9UTH5.

Family and domain databases

InterProiIPR016035. Acyl_Trfase/lysoPLipase.
IPR002642. LysoPLipase_cat_dom.
[Graphical view]
PfamiPF01735. PLA2_B. 1 hit.
[Graphical view]
SMARTiSM00022. PLAc. 1 hit.
[Graphical view]
SUPFAMiSSF52151. SSF52151. 1 hit.
PROSITEiPS51210. PLA2C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9UTH5-1 [UniParc]FASTAAdd to Basket

« Hide

MYFQSFYFLA LLLATAVYGQ VASPELHSLS RRNWKKPPPF PSTNASYAPV    50
IRSCDSSEIM VNSLPRGELP DLENDFIEKR LSNANEALTT FLQSKNTTAD 100
LDLSSIVGDN GPRLGIAVSG GGWRSMLFGG GALAALDSRS NETTLGGLLQ 150
SAHYITGADG GSWLLSSLAV NEFRTIQNIS KSIWYTRLGI FFIEETHFGD 200
LKNYYTNVVD EVNQKAAAGF NVSLTDYWGR AIARHFVGQL RGGPNLTYSS 250
VQNASWFQTA EYPYPLIVTQ GLTGGLPDGS NGTATNSSIY EISPYYLTSF 300
DNNVRSYTPT QYLGTNYSNG TAVDGKCVTQ FDNVGFLVGT SSTRYNEALI 350
DVSLRQSRMS RRLGFTLRHM RINGSSVSFY PNPYTDATDI AGNATAVSED 400
IVDTPYLDLF DGGYDGQNIP IWPLLQPERK LDVVFAFDSS GDTSNFWPNG 450
SSLVATYERV TQRASDAVYD VEDFVHVPTP ETFVNLGLNA NPTFFGCDGR 500
NTTRGDVPVD HNTPPLVVYM PNTPWTMKSN LVDHRYRIAN SEIQALIQNG 550
FVATTQDNST DFASCLACAV VQRSLERRNQ STSAACQQCF SQYCWNGTVD 600
NTPVDDDSKN PTYNPAVKTS SASGVHANIL LSFFVLLATL LVTA 644
Length:644
Mass (Da):70,570
Last modified:May 1, 2000 - v1
Checksum:iEB42D2427EA804D1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU329670 Genomic DNA. Translation: CAB57433.1.
AB027917 Genomic DNA. Translation: BAA87221.1.
PIRiT37800.
RefSeqiNP_594024.1. NM_001019449.2.

Genome annotation databases

EnsemblFungiiSPAC1786.02.1; SPAC1786.02.1:pep; SPAC1786.02.
GeneIDi2542164.
KEGGispo:SPAC1786.02.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU329670 Genomic DNA. Translation: CAB57433.1 .
AB027917 Genomic DNA. Translation: BAA87221.1 .
PIRi T37800.
RefSeqi NP_594024.1. NM_001019449.2.

3D structure databases

ProteinModelPortali Q9UTH5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 278640. 3 interactions.
MINTi MINT-4710476.
STRINGi 4896.SPAC1786.02-1.

Proteomic databases

MaxQBi Q9UTH5.
PaxDbi Q9UTH5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii SPAC1786.02.1 ; SPAC1786.02.1:pep ; SPAC1786.02 .
GeneIDi 2542164.
KEGGi spo:SPAC1786.02.

Organism-specific databases

PomBasei SPAC1786.02.

Phylogenomic databases

eggNOGi NOG290086.
HOGENOMi HOG000189547.
KOi K13333.
OMAi VHANILL.
OrthoDBi EOG7N37NC.
PhylomeDBi Q9UTH5.

Miscellaneous databases

NextBioi 20803236.

Family and domain databases

InterProi IPR016035. Acyl_Trfase/lysoPLipase.
IPR002642. LysoPLipase_cat_dom.
[Graphical view ]
Pfami PF01735. PLA2_B. 1 hit.
[Graphical view ]
SMARTi SM00022. PLAc. 1 hit.
[Graphical view ]
SUPFAMi SSF52151. SSF52151. 1 hit.
PROSITEi PS51210. PLA2C. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. "Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library."
    Ding D.-Q., Tomita Y., Yamamoto A., Chikashige Y., Haraguchi T., Hiraoka Y.
    Genes Cells 5:169-190(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 1-102.
    Strain: ATCC 38364 / 968.

Entry informationi

Entry nameiPLB6_SCHPO
AccessioniPrimary (citable) accession number: Q9UTH5
Secondary accession number(s): Q9UTZ2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 23, 2003
Last sequence update: May 1, 2000
Last modified: May 14, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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