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Q9UTH5 (PLB6_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 88. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable lysophospholipase C1786.02

EC=3.1.1.5
Alternative name(s):
Phospholipase B
Gene names
ORF Names:SPAC1786.02
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces

Protein attributes

Sequence length644 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the release of fatty acids from lysophospholipids By similarity.

Catalytic activity

2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.

Subcellular location

Secreted Probable.

Sequence similarities

Belongs to the lysophospholipase family.

Contains 1 PLA2c domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1919 Potential
Chain20 – 644625Probable lysophospholipase C1786.02
PRO_0000024644

Regions

Domain53 – 600548PLA2c

Amino acid modifications

Glycosylation441N-linked (GlcNAc...) Potential
Glycosylation961N-linked (GlcNAc...) Potential
Glycosylation1411N-linked (GlcNAc...) Potential
Glycosylation1781N-linked (GlcNAc...) Potential
Glycosylation2211N-linked (GlcNAc...) Potential
Glycosylation2451N-linked (GlcNAc...) Potential
Glycosylation2531N-linked (GlcNAc...) Potential
Glycosylation2811N-linked (GlcNAc...) Potential
Glycosylation2861N-linked (GlcNAc...) Potential
Glycosylation3161N-linked (GlcNAc...) Potential
Glycosylation3191N-linked (GlcNAc...) Potential
Glycosylation3731N-linked (GlcNAc...) Potential
Glycosylation3931N-linked (GlcNAc...) Potential
Glycosylation4491N-linked (GlcNAc...) Potential
Glycosylation5011N-linked (GlcNAc...) Potential
Glycosylation5581N-linked (GlcNAc...) Potential
Glycosylation5791N-linked (GlcNAc...) Potential
Glycosylation5961N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q9UTH5 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: EB42D2427EA804D1

FASTA64470,570
        10         20         30         40         50         60 
MYFQSFYFLA LLLATAVYGQ VASPELHSLS RRNWKKPPPF PSTNASYAPV IRSCDSSEIM 

        70         80         90        100        110        120 
VNSLPRGELP DLENDFIEKR LSNANEALTT FLQSKNTTAD LDLSSIVGDN GPRLGIAVSG 

       130        140        150        160        170        180 
GGWRSMLFGG GALAALDSRS NETTLGGLLQ SAHYITGADG GSWLLSSLAV NEFRTIQNIS 

       190        200        210        220        230        240 
KSIWYTRLGI FFIEETHFGD LKNYYTNVVD EVNQKAAAGF NVSLTDYWGR AIARHFVGQL 

       250        260        270        280        290        300 
RGGPNLTYSS VQNASWFQTA EYPYPLIVTQ GLTGGLPDGS NGTATNSSIY EISPYYLTSF 

       310        320        330        340        350        360 
DNNVRSYTPT QYLGTNYSNG TAVDGKCVTQ FDNVGFLVGT SSTRYNEALI DVSLRQSRMS 

       370        380        390        400        410        420 
RRLGFTLRHM RINGSSVSFY PNPYTDATDI AGNATAVSED IVDTPYLDLF DGGYDGQNIP 

       430        440        450        460        470        480 
IWPLLQPERK LDVVFAFDSS GDTSNFWPNG SSLVATYERV TQRASDAVYD VEDFVHVPTP 

       490        500        510        520        530        540 
ETFVNLGLNA NPTFFGCDGR NTTRGDVPVD HNTPPLVVYM PNTPWTMKSN LVDHRYRIAN 

       550        560        570        580        590        600 
SEIQALIQNG FVATTQDNST DFASCLACAV VQRSLERRNQ STSAACQQCF SQYCWNGTVD 

       610        620        630        640 
NTPVDDDSKN PTYNPAVKTS SASGVHANIL LSFFVLLATL LVTA 

« Hide

References

[1]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.
[2]"Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library."
Ding D.-Q., Tomita Y., Yamamoto A., Chikashige Y., Haraguchi T., Hiraoka Y.
Genes Cells 5:169-190(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 1-102.
Strain: ATCC 38364 / 968.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU329670 Genomic DNA. Translation: CAB57433.1.
AB027917 Genomic DNA. Translation: BAA87221.1.
PIRT37800.
RefSeqNP_594024.1. NM_001019449.2.

3D structure databases

ProteinModelPortalQ9UTH5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid278640. 3 interactions.
MINTMINT-4710476.
STRING4896.SPAC1786.02-1.

Proteomic databases

MaxQBQ9UTH5.
PaxDbQ9UTH5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPAC1786.02.1; SPAC1786.02.1:pep; SPAC1786.02.
GeneID2542164.
KEGGspo:SPAC1786.02.

Organism-specific databases

PomBaseSPAC1786.02.

Phylogenomic databases

eggNOGNOG290086.
HOGENOMHOG000189547.
KOK13333.
OMAVHANILL.
OrthoDBEOG7N37NC.
PhylomeDBQ9UTH5.

Family and domain databases

InterProIPR016035. Acyl_Trfase/lysoPLipase.
IPR002642. LysoPLipase_cat_dom.
[Graphical view]
PfamPF01735. PLA2_B. 1 hit.
[Graphical view]
SMARTSM00022. PLAc. 1 hit.
[Graphical view]
SUPFAMSSF52151. SSF52151. 1 hit.
PROSITEPS51210. PLA2C. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20803236.

Entry information

Entry namePLB6_SCHPO
AccessionPrimary (citable) accession number: Q9UTH5
Secondary accession number(s): Q9UTZ2
Entry history
Integrated into UniProtKB/Swiss-Prot: May 23, 2003
Last sequence update: May 1, 2000
Last modified: May 14, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names