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Protein

Probable 6-phosphofructo-2-kinase C222.13c

Gene

SPAC222.13c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Synthesis of fructose 2,6-bisphosphate.By similarity

Catalytic activityi

ATP + D-fructose 6-phosphate = ADP + beta-D-fructose 2,6-bisphosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei235 – 2351Sequence analysis
Active sitei266 – 2661Sequence analysis
Binding sitei300 – 3001Fructose-6-phosphateBy similarity
Active sitei527 – 5271Proton donorBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi150 – 1578ATPSequence analysis

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable 6-phosphofructo-2-kinase C222.13c (EC:2.7.1.105)
Gene namesi
ORF Names:SPAC222.13c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC222.13c.
PomBaseiSPAC222.13c.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: PomBase
  • cytosol Source: PomBase
  • nucleus Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 592592Probable 6-phosphofructo-2-kinase C222.13cPRO_0000318496Add
BLAST

Proteomic databases

MaxQBiQ9UTE1.

Interactioni

Protein-protein interaction databases

BioGridi278435. 7 interactions.
MINTiMINT-4710227.

Structurei

3D structure databases

ProteinModelPortaliQ9UTE1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000181112.
InParanoidiQ9UTE1.
KOiK00900.
OMAiTHERRKH.
OrthoDBiEOG092C2SJU.
PhylomeDBiQ9UTE1.

Family and domain databases

CDDicd07067. HP_PGM_like. 1 hit.
Gene3Di3.40.50.1240. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003094. 6Pfruct_kin.
IPR013079. 6Phosfructo_kin.
IPR013078. His_Pase_superF_clade-1.
IPR029033. His_PPase_superfam.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR10606. PTHR10606. 1 hit.
PfamiPF01591. 6PF2K. 1 hit.
PF00300. His_Phos_1. 1 hit.
[Graphical view]
PRINTSiPR00991. 6PFRUCTKNASE.
SMARTiSM00855. PGAM. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF53254. SSF53254. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9UTE1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNTGSARTE EFTKGTGYEA TKPNNDTDDD AKQNYPSKEP HMKLGDYTEE
60 70 80 90 100
TSFVDDSIFK REELTPDRNS PANDVEKMEV PKPTPQWMKL KDEGKLGKHR
110 120 130 140 150
KNRLRRPGRF PVRQESTIDI PGLTVSKRTE NDSNNASYGI REKLIIILVG
160 170 180 190 200
IPATGKSYIG SKLSRYYNWL KYNCRFFSVG DKRREEGAST YSMSADFFDI
210 220 230 240 250
KNEETFKFRE NVALETLEDL LHWMIHENGV IGILDATNST HERRKHLYDR
260 270 280 290 300
ISKEADIGIM FLESLCTDDI LFEENIKLKI KGPDYEGYDT ESALKDLRER
310 320 330 340 350
VDLYKKYYEP LDERDEQLPF LQYVKVINVG IKVVTHNIEG FLAGQAVYFM
360 370 380 390 400
LNLNIQKRQI WLTRPGESLD TVAGRIGGDA SLTPIGKQYA QDLANFMDRQ
410 420 430 440 450
RVLWQLRYTN DLASTNKRFS LSEASSFNVW SSVRKRAIET IEFFNPDSYN
460 470 480 490 500
VKKIRLLNDL NLGSREGLTL REFSEKYPDE FDVIKRKDYA YRFSGQGGES
510 520 530 540 550
YLDVIHRLQP LIVEIERSSG NILVVSHRIV SNILMTYFLN YHPEDIIDVG
560 570 580 590
LPLHTLFCIE SDRYGTTCMA YRYDAANRQF IKDPMFDLRK RT
Length:592
Mass (Da):68,640
Last modified:May 1, 2000 - v1
Checksum:iF0E96E375D343963
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB60705.1.
PIRiT50154.
RefSeqiNP_593152.1. NM_001018549.2.

Genome annotation databases

EnsemblFungiiSPAC222.13c.1; SPAC222.13c.1:pep; SPAC222.13c.
GeneIDi2541948.
KEGGispo:SPAC222.13c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB60705.1.
PIRiT50154.
RefSeqiNP_593152.1. NM_001018549.2.

3D structure databases

ProteinModelPortaliQ9UTE1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi278435. 7 interactions.
MINTiMINT-4710227.

Proteomic databases

MaxQBiQ9UTE1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC222.13c.1; SPAC222.13c.1:pep; SPAC222.13c.
GeneIDi2541948.
KEGGispo:SPAC222.13c.

Organism-specific databases

EuPathDBiFungiDB:SPAC222.13c.
PomBaseiSPAC222.13c.

Phylogenomic databases

HOGENOMiHOG000181112.
InParanoidiQ9UTE1.
KOiK00900.
OMAiTHERRKH.
OrthoDBiEOG092C2SJU.
PhylomeDBiQ9UTE1.

Miscellaneous databases

PROiQ9UTE1.

Family and domain databases

CDDicd07067. HP_PGM_like. 1 hit.
Gene3Di3.40.50.1240. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003094. 6Pfruct_kin.
IPR013079. 6Phosfructo_kin.
IPR013078. His_Pase_superF_clade-1.
IPR029033. His_PPase_superfam.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR10606. PTHR10606. 1 hit.
PfamiPF01591. 6PF2K. 1 hit.
PF00300. His_Phos_1. 1 hit.
[Graphical view]
PRINTSiPR00991. 6PFRUCTKNASE.
SMARTiSM00855. PGAM. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF53254. SSF53254. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYFMD_SCHPO
AccessioniPrimary (citable) accession number: Q9UTE1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: May 1, 2000
Last modified: September 7, 2016
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.