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Q9UTA4 (POPI_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonucleases P/MRP protein subunit pop1

EC=3.1.26.5
Gene names
Name:pop1
ORF Names:SPAC25B8.16
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces

Protein attributes

Sequence length698 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Required for processing of 5.8S rRNA (short form) at site A3 and for 5' and 3' processing of pre-tRNA By similarity.

Catalytic activity

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.

Subunit structure

Component of nuclear RNase P and RNase MRP complexes By similarity.

Subcellular location

Nucleusnucleolus Ref.2 Ref.3.

Sequence similarities

Belongs to the POP1 family.

Sequence caution

The sequence BAA87135.1 differs from that shown. Reason: Erroneous initiation.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 698698Ribonucleases P/MRP protein subunit pop1
PRO_0000337990

Sequences

Sequence LengthMass (Da)Tools
Q9UTA4 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 987A6BD0BA2C2427

FASTA69879,931
        10         20         30         40         50         60 
MKRSTGGTQP KGLNVKRSKL ADARFIEVES PALSNGAVDL KKFIESRSFE ITALQDAMKR 

        70         80         90        100        110        120 
SKESSAQRAF QALPRCLRRR AASHNIKRIP KGLRDRALYE MQLSSSSTLP IAPSRQRLKR 

       130        140        150        160        170        180 
FIKRLRRKLA KSGETKAIDS TGSLVTDNST DDSRIPSLAA VKLIRGKFAG RQLRKVWLPT 

       190        200        210        220        230        240 
HLWVCKRAHM INAWGYAIPE KPTEKSYRPT HRAAFRKDAI AFDMSYEPLF CISGPYEALK 

       250        260        270        280        290        300 
EKFGNSFANG LPPVFLNSSR SFTSYLVKSD IHELICPCFL QWNNPTEDDK KQIPVKNPTE 

       310        320        330        340        350        360 
CVQLVIRLHP SAFLQAWNYL SGIAVLDDRI AMHDWRLDLA SFDIHGPDSN IMLHKVFDDV 

       370        380        390        400        410        420 
ELDEAGKVWQ SISNYSSACL PMGASISVKA LVNTRCDKNL SEKGEKSLLD SAENSLPASA 

       430        440        450        460        470        480 
NQYSTHFRYW ERQEIPSFAV FENKNRHTHE KKSSEKEVIP VYITYRKEWN GLTVILPWDY 

       490        500        510        520        530        540 
AKFVWRKMMY QKGIRFGGLE NLHQIAFEKR MPFFPIDYPD TISGQLCEEE RKKRNEDSWK 

       550        560        570        580        590        600 
RRPPAKRVNY QKFGDNFSEI GNPFCCDWVY LNEMVKASRD EDKTLQLVRV QVQLVQRGSL 

       610        620        630        640        650        660 
QDRARIYCLS DDELSKWKTI IYKENLTAEN LLYPKCPNET AIIGFVTTGN FNLNAGKPSG 

       670        680        690 
IANVLAKTIK NEKSGYCIIR NVGCSVPRLA QWKFNQSH 

« Hide

References

[1]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.
[2]"Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library."
Ding D.-Q., Tomita Y., Yamamoto A., Chikashige Y., Haraguchi T., Hiraoka Y.
Genes Cells 5:169-190(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 1-61, SUBCELLULAR LOCATION.
Strain: ATCC 38364 / 968.
[3]"ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU329670 Genomic DNA. Translation: CAB61782.1.
AB027831 Genomic DNA. Translation: BAA87135.1. Different initiation.
PIRT50203.
RefSeqNP_594476.1. NM_001019905.2.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid278048. 1 interaction.
STRING4896.SPAC25B8.16-1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPAC25B8.16.1; SPAC25B8.16.1:pep; SPAC25B8.16.
GeneID2541548.
KEGGspo:SPAC25B8.16.

Organism-specific databases

PomBaseSPAC25B8.16.

Phylogenomic databases

eggNOGNOG297409.
KOK01164.
OMARQDDRIP.
PhylomeDBQ9UTA4.

Family and domain databases

InterProIPR012590. POPLD.
IPR009723. RNase_P/MRP_POP1.
[Graphical view]
PfamPF06978. POP1. 1 hit.
PF08170. POPLD. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20802645.
PROQ9UTA4.

Entry information

Entry namePOPI_SCHPO
AccessionPrimary (citable) accession number: Q9UTA4
Secondary accession number(s): Q9UU39
Entry history
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: May 1, 2000
Last modified: April 16, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names