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Q9UT45 (ENG1_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 86. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Endo-1,3(4)-beta-glucanase 1

Short name=Endo-1,3-beta-glucanase 1
Short name=Endo-1,4-beta-glucanase 1
EC=3.2.1.6
Alternative name(s):
Laminarinase-1
Gene names
Name:eng1
ORF Names:SPAC821.09
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces

Protein attributes

Sequence length1016 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Has a role in cell separation where it is required for the degradation of the primary septum after completion of cytokinesis. Ref.3

Catalytic activity

Endohydrolysis of (1->3)- or (1->4)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolyzed is itself substituted at C-3.

Subcellular location

Cell septum. Note: Localized in a ring-like structure around the septum. Ref.2 Ref.3

Sequence similarities

Belongs to the glycosyl hydrolase 81 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2020 Potential
Chain21 – 1016996Endo-1,3(4)-beta-glucanase 1
PRO_0000012132

Regions

Compositional bias752 – 956205Thr-rich

Amino acid modifications

Glycosylation371N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q9UT45 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 9240CA34D35786FC

FASTA1,016109,743
        10         20         30         40         50         60 
MSSYLRSFIF GLLTISLAQC SPILKDTKDT KFSTGSNISL KKRDTNVFDS VVDTINPASY 

        70         80         90        100        110        120 
FGTVSHPVTP AGVSTDSLSS PIETNKFFDN NLLGSRTNFM YADPFRYWWQ SSDTMGGICI 

       130        140        150        160        170        180 
AHTDDNQRVM DTDDTIPSYY YEPIGICSLG FGASGITSNT DPIVDEIDQM SARFTFSWDS 

       190        200        210        220        230        240 
SSMQLTLTEG MAVTTAVYTN AIPQIFSSTL YINDFVEVPG TSAVQKYRVT MSDNHVWLIY 

       250        260        270        280        290        300 
IYGDSLTLTE STSQMLVGSN TFNGYIQIAK IPLGDGTAEA LYDTYAGVYI TGISISGYVE 

       310        320        330        340        350        360 
DAVGYYSFDF TTAGDTSVEP LFFLLPHQVD TAVSGTKVTS IVLASLVSGD MNAAAGNSIT 

       370        380        390        400        410        420 
FAEAIPQDIG FLPWSPTGGQ IGYSEEALEI IAEVAGTELG EDFSANSNLN SMYYSGKVLA 

       430        440        450        460        470        480 
KYAMLCVTIN DILGDETSSE QCIQKLEAAF ARFVDNQQIY PLTYDNTWKG VVSVAGLSGD 

       490        500        510        520        530        540 
SLADFGNSYY NDHHFHYGYF VFTAAVIGHI DPDWINTGNN KEWVNFLVRD VANPSSNDPY 

       550        560        570        580        590        600 
FPKHRMIDIY HGHGWASGLF ESNDGKDEES TSEDYNFFFG MKLWGQVIGD SDMEDRANII 

       610        620        630        640        650        660 
LGIERNALNK YMLYADGNVQ PTSMQPNYVA GITFMNKITH TTYFGTNIEY IQGIHMLPIT 

       670        680        690        700        710        720 
PISAFIRGPS FVLAEWNALL ASVIDYVDSG WRSLLYANLA IAEPEESYEY FSSSDFNTDY 

       730        740        750        760        770        780 
LDDGASRAWY LAYAAGLWAN DAVYYPVSSS STTTTSTSTG SVTTTSTTAT ASCTLPISYT 

       790        800        810        820        830        840 
STPTTTSISG TCNGATFDAS LYVCDGTVLC PIVNGVSYQN CNGACYNPSQ YGCDNGALGP 

       850        860        870        880        890        900 
VQSSSTTSSI TPTPTTTSSI TPTPTTTSTT TTAQSTGMQL CGSNYYDASS YYCDNDQLCP 

       910        920        930        940        950        960 
IIDGVDYLSC NGACYNPSQY VCSDGSLSPN TVTTTKATTT FTPTPTTTTT PTPTTTSATS 

       970        980        990       1000       1010 
TNVIAQCGSA WYDSQSYICY GNILCPIING SPLLACGNAC YDSSIYGCSN GALVAA 

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.
[2]"Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library."
Ding D.-Q., Tomita Y., Yamamoto A., Chikashige Y., Haraguchi T., Hiraoka Y.
Genes Cells 5:169-190(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 1-168, SUBCELLULAR LOCATION.
Strain: ATCC 38364 / 968.
[3]"The endo-beta-1,3-glucanase eng1p is required for dissolution of the primary septum during cell separation in Schizosaccharomyces pombe."
Martin-Cuadrado A.B., Duenas E., Sipiczki M., de Aldana C.R.V., del Rey F.
J. Cell Sci. 116:1689-1698(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, SUBCELLULAR LOCATION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU329670 Genomic DNA. Translation: CAB57443.1.
AB027918 Genomic DNA. Translation: BAA87222.1. Sequence problems.
PIRT41720.
RefSeqNP_593162.1. NM_001018560.2.

3D structure databases

ProteinModelPortalQ9UT45.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid279801. 17 interactions.
STRING4896.SPAC821.09-1.

Protein family/group databases

CAZyCBM52. Carbohydrate-Binding Module Family 52.
GH81. Glycoside Hydrolase Family 81.
mycoCLAPLAM81A_SCHPO.

Proteomic databases

MaxQBQ9UT45.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPAC821.09.1; SPAC821.09.1:pep; SPAC821.09.
GeneID2543379.
KEGGspo:SPAC821.09.

Organism-specific databases

PomBaseSPAC821.09.

Phylogenomic databases

eggNOGCOG5498.
OMAIHMLPLM.
OrthoDBEOG7MSMXB.
PhylomeDBQ9UT45.

Family and domain databases

InterProIPR018909. CBM_septum.
IPR005200. Glyco_hydro_81.
[Graphical view]
PfamPF10645. Carb_bind. 3 hits.
PF03639. Glyco_hydro_81. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20804394.

Entry information

Entry nameENG1_SCHPO
AccessionPrimary (citable) accession number: Q9UT45
Secondary accession number(s): Q9UTZ1
Entry history
Integrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: May 1, 2000
Last modified: May 14, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries