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Protein

Putative phospholipid-transporting ATPase C821.13c

Gene

SPAC821.13c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + H2O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2).

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei6844-aspartylphosphate intermediateBy similarity1
Metal bindingi1243MagnesiumBy similarity1
Metal bindingi1247MagnesiumBy similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

ATP-binding, Magnesium, Metal-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative phospholipid-transporting ATPase C821.13c (EC:3.6.3.1)
Gene namesi
ORF Names:SPAC821.13c, SPAC955.01c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC821.13c.
PomBaseiSPAC821.13c.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 275ExtracellularSequence analysisAdd BLAST275
Transmembranei276 – 296HelicalSequence analysisAdd BLAST21
Topological domaini297 – 574CytoplasmicSequence analysisAdd BLAST278
Transmembranei575 – 595HelicalSequence analysisAdd BLAST21
Topological domaini596 – 614ExtracellularSequence analysisAdd BLAST19
Transmembranei615 – 635HelicalSequence analysisAdd BLAST21
Topological domaini636 – 1309CytoplasmicSequence analysisAdd BLAST674
Transmembranei1310 – 1330HelicalSequence analysisAdd BLAST21
Topological domaini1331 – 1332ExtracellularSequence analysis2
Transmembranei1333 – 1353HelicalSequence analysisAdd BLAST21
Topological domaini1354 – 1381CytoplasmicSequence analysisAdd BLAST28
Transmembranei1382 – 1402HelicalSequence analysisAdd BLAST21
Topological domaini1403 – 1414ExtracellularSequence analysisAdd BLAST12
Transmembranei1415 – 1435HelicalSequence analysisAdd BLAST21
Topological domaini1436 – 1443CytoplasmicSequence analysis8
Transmembranei1444 – 1464HelicalSequence analysisAdd BLAST21
Topological domaini1465 – 1490ExtracellularSequence analysisAdd BLAST26
Transmembranei1491 – 1511HelicalSequence analysisAdd BLAST21
Topological domaini1512 – 1562CytoplasmicSequence analysisAdd BLAST51

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000462401 – 1562Putative phospholipid-transporting ATPase C821.13cAdd BLAST1562

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei954Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ9UT43.
PRIDEiQ9UT43.

PTM databases

iPTMnetiQ9UT43.

Interactioni

Protein-protein interaction databases

BioGridi280591. 1 interactor.

Structurei

3D structure databases

ProteinModelPortaliQ9UT43.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi125 – 132Poly-Lys8
Compositional biasi338 – 346Poly-Arg9

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000190484.
InParanoidiQ9UT43.
KOiK01530.
OMAiDIFQEYE.
OrthoDBiEOG092C0BQ4.
PhylomeDBiQ9UT43.

Family and domain databases

Gene3Di2.70.150.10. 3 hits.
3.40.1110.10. 3 hits.
3.40.50.1000. 2 hits.
InterProiIPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR006539. P-type_ATPase_IV.
IPR032631. P-type_ATPase_N.
IPR001757. P_typ_ATPase.
IPR032630. P_typ_ATPase_c.
[Graphical view]
PANTHERiPTHR24092. PTHR24092. 3 hits.
PfamiPF00122. E1-E2_ATPase. 1 hit.
PF16212. PhoLip_ATPase_C. 1 hit.
PF16209. PhoLip_ATPase_N. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 3 hits.
SSF81660. SSF81660. 1 hit.
TIGRFAMsiTIGR01652. ATPase-Plipid. 2 hits.
TIGR01494. ATPase_P-type. 1 hit.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9UT43-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSSGIAGDS NGFETNFLNE TTNREEDGAF NWNAADDGTN ERREDIHVRF
60 70 80 90 100
QDSALPLGID ENELDEIDIN GDSKKLDSVE VDESHDVNSP SDSRLKSSFK
110 120 130 140 150
SVLELTANSM VSVLTPSTKT EQTSKGKGKK KKAHVSFLEG PVEEIPLDDI
160 170 180 190 200
EPTSPREASP VFNGRPPIPP EFLKSRHKEF TIPNPLQFIS NFLSNLFSRD
210 220 230 240 250
TRYLKSSHGR IIIINPYDDS SQIDERTGKP YMQNSIVSSR YNKYNFVPLQ
260 270 280 290 300
IIAQFSKTAN CYFLLIAIMQ MIPGWSTTGT YTTIIPLLIF ISIAILREGF
310 320 330 340 350
DNYRRYRQDR VENRIQTQVL RHVDVDPPIV EEHSSFFRRR RWRRSRSQES
360 370 380 390 400
ASRSTIRSTD EREPERTSED PPQLPPSPSS PSSPALSVKP NIDPQPPLYN
410 420 430 440 450
STLTTTRSIP ANKPTFFWAS CDRKDVRVGD IIRLTSDQTL PADVIALSSP
460 470 480 490 500
NPNGAIYIET AALDGETSLK TRLVNSTLRS LCKDINDLIR LSGTCTVEDP
510 520 530 540 550
NGDLYNFNGS MKLDSIQGEI PLSNNDVLYR GSNLRNTSEL FALVIFTGEE
560 570 580 590 600
SKIRMNAVRN VSVKAPSMQK VTNRIVIFIF ALVVSMAIYC TAAYFVWQKK
610 620 630 640 650
VERKLWYLTN SKLSFVPILV SFIILYNTMV PISLYVSMEI IRVFQTFLVQ
660 670 680 690 700
SDIDLYYPEN DTRCEVRSSS ILEELGQVTH VFSDKTGTLT DNIMLFRNLS
710 720 730 740 750
VGGFAWQHVG AENPKLVSTS QKSDDLDGEA KPPQLENIQG TTIQLLQYVH
760 770 780 790 800
DNPHTTFSKR VRIFLLNLAI CHTCLPSFDE ENQIYKYQSI SPDELALVHA
810 820 830 840 850
AQQLGYIVID RDIDSLTIRL HYPLDPHSHP IAKTYRILNI IEFTSKRKCM
860 870 880 890 900
SVIVRMPNGR ICLFCKGADS AIIKRLRLSN LAKRKDKSVT KAEQARKSIE
910 920 930 940 950
IDKAIIRNSQ STSRPSLTAS RPSLSRRRND YINNVTSWLD ERREKMGVVR
960 970 980 990 1000
PRASTSILET RRRPAVGRHS LAGGERLMED KKYLSKQEEA EGSIYESLNH
1010 1020 1030 1040 1050
NDAKLFENTF EHVHAFATDG LRTLMYAHRF IDESEYQSWK LVNDAALNSL
1060 1070 1080 1090 1100
SNRQQLLDEA ADLIEKDLEF AGATAIEDKL QVGVPESINS LFRAGIKFWM
1110 1120 1130 1140 1150
LTGDKKETAI NIGHSCGVIK EYSTVVVMGS LDGVEGSDET VSGGQRLSLD
1160 1170 1180 1190 1200
RPPTNDPASL MIHQLISCMN AIHSNSLAHL VIVIDGSTLA DIENDPELFL
1210 1220 1230 1240 1250
LFINTAVEAD SVICCRSSPM QKALMVQKVR NTLEKAVTLA IGDGANDIAM
1260 1270 1280 1290 1300
IQEAHVGIGI AGREGLQAAR SSDFSIGRFK FLIKLLFCHG RWSYVRLSKY
1310 1320 1330 1340 1350
ILGTFYKEQF FFLMQAIMQP FVGYTGQSLY ESWGLTCFNT LFSSLCVIGL
1360 1370 1380 1390 1400
GIFEKDLSAS TVIAVPELYQ KGINNEAFNW RVYFGWCSIA FIQAFLVFYV
1410 1420 1430 1440 1450
TYSLFGMKEL NDNNIFAYGQ LIFTAAIFIM NFKLVFIEMQ YINIISIIVL
1460 1470 1480 1490 1500
VLTSLAWFLF NIFISEHYPD KNLYLARSQF LHHFGKNPSW WLTMLFVMVC
1510 1520 1530 1540 1550
ALTIDIVAQM LRRTLRPTDT DIFVEMENDA FVRSRFEQES GEFLQANAPS
1560
VDEIEQYLKS RD
Length:1,562
Mass (Da):176,725
Last modified:May 30, 2003 - v2
Checksum:i2B2B138BF8CB5E6E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB57447.1.
PIRiT41724.
RefSeqiXP_001713045.1. XM_001712993.2.

Genome annotation databases

EnsemblFungiiSPAC821.13c.1; SPAC821.13c.1:pep; SPAC821.13c.
GeneIDi3361515.
KEGGispo:SPAC821.13c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB57447.1.
PIRiT41724.
RefSeqiXP_001713045.1. XM_001712993.2.

3D structure databases

ProteinModelPortaliQ9UT43.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi280591. 1 interactor.

PTM databases

iPTMnetiQ9UT43.

Proteomic databases

MaxQBiQ9UT43.
PRIDEiQ9UT43.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC821.13c.1; SPAC821.13c.1:pep; SPAC821.13c.
GeneIDi3361515.
KEGGispo:SPAC821.13c.

Organism-specific databases

EuPathDBiFungiDB:SPAC821.13c.
PomBaseiSPAC821.13c.

Phylogenomic databases

HOGENOMiHOG000190484.
InParanoidiQ9UT43.
KOiK01530.
OMAiDIFQEYE.
OrthoDBiEOG092C0BQ4.
PhylomeDBiQ9UT43.

Miscellaneous databases

PROiQ9UT43.

Family and domain databases

Gene3Di2.70.150.10. 3 hits.
3.40.1110.10. 3 hits.
3.40.50.1000. 2 hits.
InterProiIPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR006539. P-type_ATPase_IV.
IPR032631. P-type_ATPase_N.
IPR001757. P_typ_ATPase.
IPR032630. P_typ_ATPase_c.
[Graphical view]
PANTHERiPTHR24092. PTHR24092. 3 hits.
PfamiPF00122. E1-E2_ATPase. 1 hit.
PF16212. PhoLip_ATPase_C. 1 hit.
PF16209. PhoLip_ATPase_N. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 3 hits.
SSF81660. SSF81660. 1 hit.
TIGRFAMsiTIGR01652. ATPase-Plipid. 2 hits.
TIGR01494. ATPase_P-type. 1 hit.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYFRD_SCHPO
AccessioniPrimary (citable) accession number: Q9UT43
Secondary accession number(s): Q9P6S8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2003
Last sequence update: May 30, 2003
Last modified: November 30, 2016
This is version 119 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.