Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

RNA polymerase I-specific transcription initiation factor rrn7

Gene

rrn7

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Component of RNA polymerase I core factor complex (CF) that acts as a sua7/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds HomolD box in rDNA promoters and plays a role in Pol I recruitment.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi11ZincBy similarity1
Metal bindingi16ZincBy similarity1
Metal bindingi30ZincBy similarity1
Metal bindingi34ZincBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri4 – 37RRN7-typeAdd BLAST34

GO - Molecular functioni

GO - Biological processi

  • positive regulation of transcription from RNA polymerase II promoter Source: PomBase
  • transcription from RNA polymerase I promoter Source: PomBase
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
RNA polymerase I-specific transcription initiation factor rrn7
Gene namesi
Name:rrn7
ORF Names:SPBC336.09c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC336.09c.
PomBaseiSPBC336.09c. rrn7.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: PomBase
  • nucleus Source: PomBase
  • RNA polymerase I core factor complex Source: PomBase
  • RNA polymerase I transcription factor complex Source: PomBase
  • RNA polymerase transcription factor SL1 complex Source: GO_Central
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000974491 – 537RNA polymerase I-specific transcription initiation factor rrn7Add BLAST537

Proteomic databases

MaxQBiQ9UST5.
PRIDEiQ9UST5.

Interactioni

Subunit structurei

Component of the core factor (CF) complex. Interacts with acr1.1 Publication

Protein-protein interaction databases

BioGridi276768. 2 interactors.
MINTiMINT-4708726.

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni38 – 64B-readerBy similarityAdd BLAST27
Regioni65 – 80B-linkerBy similarityAdd BLAST16
Regioni81 – 232N-terminal cyclin foldBy similarityAdd BLAST152
Regioni233 – 349C-terminal cyclin foldBy similarityAdd BLAST117

Domaini

Although it shares weak sequence similarity with sua7/TFIIB, displays a similar subdomain organization as sua7/TFIIB, with a N-terminal zinc finger, a connecting region (composed of B-reader and B-linker regions), followed by 2 cyclin folds.By similarity

Sequence similaritiesi

Belongs to the RRN7/TAF1B family.Curated
Contains 1 RRN7-type zinc finger.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri4 – 37RRN7-typeAdd BLAST34

Keywords - Domaini

Zinc-finger

Phylogenomic databases

InParanoidiQ9UST5.
KOiK15219.
OMAiCRSRLYR.
OrthoDBiEOG092C3OWR.
PhylomeDBiQ9UST5.

Family and domain databases

InterProiIPR033599. TAF1B/Rrn7.
IPR021752. TF_Rrn7_Zf.
[Graphical view]
PANTHERiPTHR31576:SF2. PTHR31576:SF2. 1 hit.
PfamiPF11781. zf-RRN7. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9UST5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGNWFEGPP CSVRNCKSTW YFKNAGQTFC RRGHAQHGIE IAQDDEPGAG
60 70 80 90 100
TFYQTRKRKV VRNHLDTGDE DEIVYGTAGR SLYLQAFQII LQLQCQALTT
110 120 130 140 150
KLGFDQRIEG MIRDLWALYL SLSYESFTSS FLSLNQNSTQ SESSDSDFDL
160 170 180 190 200
IDPESQPGAD PSSRKTKETS QSHSISYPRL LYSSAFIYVA CLLLRLPLTI
210 220 230 240 250
HKLEVLIRKN IIPYYRAYKQ IPLKIFKRLQ KNYVRMLIPF HYPTYQRIQS
260 270 280 290 300
AVLTLVDVLV SKYELKVPPP NEPLILFELI NSFFFPLEIF IPASRLLNLV
310 320 330 340 350
HSQISLQGTS SDNYQSKIRS AQSIHEKLSD AEVMLLATIL VAANVCYGFD
360 370 380 390 400
DAQTRNSKYK DSMFTVKTNW NMWLSQVQKI NEKEKDKFYE IDEQSILTLN
410 420 430 440 450
NSEMDKYFQW YEKEFVEENN PNNIPEGILN VFPILSKDSH LQENQPTDIL
460 470 480 490 500
TDESVIAEDV KLEQVFKPVG IKESDKMDFS RRKDAYISML PFSPNTENTA
510 520 530
HRVTIMVAKL YNIKLDSLIA AIRYVESCLK TGIHNQD
Length:537
Mass (Da):61,911
Last modified:May 1, 2000 - v1
Checksum:i5EF44F491BAA5090
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAB58161.1.
PIRiT40247.
RefSeqiNP_596129.1. NM_001022047.2.

Genome annotation databases

EnsemblFungiiSPBC336.09c.1; SPBC336.09c.1:pep; SPBC336.09c.
GeneIDi2540236.
KEGGispo:SPBC336.09c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAB58161.1.
PIRiT40247.
RefSeqiNP_596129.1. NM_001022047.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi276768. 2 interactors.
MINTiMINT-4708726.

Proteomic databases

MaxQBiQ9UST5.
PRIDEiQ9UST5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC336.09c.1; SPBC336.09c.1:pep; SPBC336.09c.
GeneIDi2540236.
KEGGispo:SPBC336.09c.

Organism-specific databases

EuPathDBiFungiDB:SPBC336.09c.
PomBaseiSPBC336.09c. rrn7.

Phylogenomic databases

InParanoidiQ9UST5.
KOiK15219.
OMAiCRSRLYR.
OrthoDBiEOG092C3OWR.
PhylomeDBiQ9UST5.

Miscellaneous databases

PROiQ9UST5.

Family and domain databases

InterProiIPR033599. TAF1B/Rrn7.
IPR021752. TF_Rrn7_Zf.
[Graphical view]
PANTHERiPTHR31576:SF2. PTHR31576:SF2. 1 hit.
PfamiPF11781. zf-RRN7. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRRN7_SCHPO
AccessioniPrimary (citable) accession number: Q9UST5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 6, 2002
Last sequence update: May 1, 2000
Last modified: November 30, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.