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Q9USS6 (PPA4_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable acid phosphatase SPBC4.06

EC=3.1.3.2
Gene names
ORF Names:SPBC4.06
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces

Protein attributes

Sequence length462 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

A phosphate monoester + H2O = an alcohol + phosphate. UniProtKB Q9NPH0

Subcellular location

Mitochondrion Ref.2.

Sequence similarities

Belongs to the histidine acid phosphatase family.

Ontologies

Keywords
   Cellular componentMitochondrion
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentmitochondrion

Inferred from direct assay Ref.2. Source: PomBase

   Molecular_functionacid phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 462462Probable acid phosphatase SPBC4.06
PRO_0000311719

Sites

Active site351Nucleophile By similarity UniProtKB Q9NPH0
Active site3301Proton donor By similarity UniProtKB P15309

Sequences

Sequence LengthMass (Da)Tools
Q9USS6 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 113D45882EA0DFA9

FASTA46251,976
        10         20         30         40         50         60 
MSQMSSASVK FPDSVPGVDY PKQLQLKYLQ VIFRHGERAP VKERLGSAGI PKDWKLCNNA 

        70         80         90        100        110        120 
RRFFAQIKGE KEWSVLGFER KVESPVDTSL AAPTSDNSPS GVCIHGELTD FGRVTTRTLG 

       130        140        150        160        170        180 
EYLRERYVKQ LKFLPDELNN YADVYMRATP MVRALESLEH VFSGLYPESK RKMGLPVIFT 

       190        200        210        220        230        240 
RNWSDENLLP NENNCPRLVQ LYEEFAERAA KLYDPLLAGR ASEMMSQFMN GQPVRVVSSH 

       250        260        270        280        290        300 
PRLSGLLDTI NAAIGSHVDF NPNLRDEQWL RDAETAVVEE WFGGYKVSKL MRQLGAGSLL 

       310        320        330        340        350        360 
NDLSMRMENF VVAEKNGSPY HRLALYGAHD VTIAAILASL DAFDYRWPPF TSHLEMELFE 

       370        380        390        400        410        420 
DTSSKSDSQN QSGDNKTTDL KLFSDESTDA SNSAIVAASN SARDMSDWYV RITYNSTPVV 

       430        440        450        460 
MGACRGQGYK GNDTICPLSI FKDTVRALKP VEYHTMCKPV KK 

« Hide

References

[1]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.
[2]"ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU329671 Genomic DNA. Translation: CAB58405.1.
PIRT40420.
RefSeqNP_595479.1. NM_001021390.2.

3D structure databases

ProteinModelPortalQ9USS6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

MINTMINT-4708663.
STRING4896.SPBC4.06-1.

Proteomic databases

MaxQBQ9USS6.
PaxDbQ9USS6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPBC4.06.1; SPBC4.06.1:pep; SPBC4.06.
GeneID2540652.
KEGGspo:SPBC4.06.

Organism-specific databases

PomBaseSPBC4.06.

Phylogenomic databases

eggNOGNOG235758.
HOGENOMHOG000203707.
KOK01078.
OMALSGCHDT.
OrthoDBEOG735461.
PhylomeDBQ9USS6.

Family and domain databases

Gene3D3.40.50.1240. 3 hits.
InterProIPR000560. His_Pase_superF_clade-2.
IPR029033. His_PPase_superfam.
[Graphical view]
PfamPF00328. His_Phos_2. 1 hit.
[Graphical view]
SUPFAMSSF53254. SSF53254. 3 hits.
PROSITEPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20801776.
PROQ9USS6.

Entry information

Entry namePPA4_SCHPO
AccessionPrimary (citable) accession number: Q9USS6
Entry history
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: May 1, 2000
Last modified: June 11, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names