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Q9USQ2 (ALP6_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 83. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Spindle pole body component alp6
Alternative name(s):
Altered polarity protein 6
Gene names
Name:alp6
ORF Names:SPBC428.20c, SPBC902.01c
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces

Protein attributes

Sequence length832 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Component of the gamma tubule complex that is required for the regulation of both interphase microtubules and mitotic bipolar spindles.

Subcellular location

Cytoplasm › cytoskeleton › spindle pole body. Note: And the microtubule organizing center (MTOC).

Sequence similarities

Belongs to the GCP family.

Sequence caution

The sequence BAA94097.1 differs from that shown. Reason: Frameshift at position 1.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 832832Spindle pole body component alp6
PRO_0000078133

Amino acid modifications

Modified residue2861Phosphothreonine Ref.3

Experimental info

Sequence conflict665 – 67511Missing in CAA22295. Ref.2

Sequences

Sequence LengthMass (Da)Tools
Q9USQ2 [UniParc].

Last modified August 29, 2001. Version 2.
Checksum: C92771C3DBF5C01A

FASTA83295,997
        10         20         30         40         50         60 
MSEIHVKTAL SRLADKYLQN SKNPSVPYTI ETIVSFFQEI IHSISPDTFQ LDIDDILYKI 

        70         80         90        100        110        120 
YSKIPPEENN DALFSKLSNL VSRLKSQTVI HNKSQILYFL YLLSPISQSS RDVSSHLLDE 

       130        140        150        160        170        180 
SISNPINIPS TEVESSNFGQ TRYDQVPENP QITDWDEGLE NESSISIAHD SSRLNRSTET 

       190        200        210        220        230        240 
SSVQHTLITE ADLLSSISYV LQGISTEYVQ FKNELALLSK RIPVQYLLQM RALSETGLLY 

       250        260        270        280        290        300 
QELKVFSNYD PSVSQSIDGD NVSKAFINDQ SLALQSLKSV ISKELTNFLA LIASLDSQIR 

       310        320        330        340        350        360 
ADASLEKPMV TIRRCIAWTQ VAKLKLRILS SVVNDNMNQE NKKRLIQVVS KYNVHGDPLI 

       370        380        390        400        410        420 
QELSDKILTE ITGPLYEMIE NWIYKGELVD PYQEFFVKEK NGSESHDHQG QGDVVWKGKY 

       430        440        450        460        470        480 
FLDKELIPSF LSEELVDKIF LIGKSLNFAR YGCGDFDWAQ EHYQKLVKKL SYRDPHSLET 

       490        500        510        520        530        540 
VVDKAYTESI NHLVYLMEEV FHLTDHLKAI KKYLLLGQGD FVDLLMESLG NSLDQPANTL 

       550        560        570        580        590        600 
FRHNLTASLE SAIRSSNASY EPEYVLKRLD ARLLELSHGE TGWDVFTLEY KVDSPINVII 

       610        620        630        640        650        660 
TPYCSRQYLK IFNFLWRLKR IEFALAHSWR RVNLGERNVF RNLDYTKFEW HFVSCHLAEM 

       670        680        690        700        710        720 
IHFVCQLQYY ILFEVIEISW QELQLAMEKP NATLDTYIEA HEKYVTSITH KGLLGGGKSR 

       730        740        750        760        770        780 
NEDSFLHQLH DILKVILNFH DAIELLYNFS CSLSNRIRIN VPISTDALAA QYTPIKNELS 

       790        800        810        820        830 
NFTEEFQVRL QKLLHGLASH KDPEMRFLSV RLNYNEFYVS HRRRHDKDVT SQ

« Hide

References

« Hide 'large scale' references
[1]"The fission yeast gamma-tubulin complex is required in G(1) phase and is a component of the spindle assembly checkpoint."
Vardy L., Toda T.
EMBO J. 19:6098-6111(2000) [PubMed: 11080156] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], CHARACTERIZATION.
[2]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed: 11859360] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.
[3]"Phosphoproteome analysis of fission yeast."
Wilson-Grady J.T., Villen J., Gygi S.P.
J. Proteome Res. 7:1088-1097(2008) [PubMed: 18257517] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-286, MASS SPECTROMETRY.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AB040811 Genomic DNA. Translation: BAA94097.1. Frameshift.
CU329671 Genomic DNA. Translation: CAA22295.1.
PIRT50382.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ9USQ2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPBC428.20c.1; SPBC428.20c.1:pep; SPBC428.20c.
GenomeReviewsGene locus alp6 in contig CU329671_GR.

Organism-specific databases

GeneDB_SpombeSPBC428.20c.

Phylogenomic databases

eggNOGfuNOG07453.
GeneTreeEFGT00050000005929.
HOGENOMHBG331024.
OrthoDBEOG4SR14T.

Gene expression databases

ArrayExpressQ9USQ2.

Family and domain databases

InterProIPR015697. GCP3.
IPR007259. Spc97_Spc98.
[Graphical view]
PANTHERPTHR19302:SF14. GCP3. 1 hit.
PTHR19302. Spc97_Spc98. 1 hit.
PfamPF04130. Spc97_Spc98. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameALP6_SCHPO
AccessionPrimary (citable) accession number: Q9USQ2
Secondary accession number(s): O94366, Q9P954
Entry history
Integrated into UniProtKB/Swiss-Prot: August 29, 2001
Last sequence update: August 29, 2001
Last modified: December 14, 2011
This is version 83 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents