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Q9USJ6 (FMNR_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
NAD(P)H-dependent FMN reductase C4B3.06c

Short name=FMN reductase C4B3.06c
EC=1.5.1.39
Alternative name(s):
Azoreductase C4B3.06c
FMN reductase [NAD(P)H]
Gene names
ORF Names:SPCC4B3.06c
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces

Protein attributes

Sequence length200 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Has several reductase activities that are NAD(P)H-dependent and involve FMN as a cofactor. May be involved in ferric iron assimilation By similarity. UniProtKB Q07923

Catalytic activity

FMNH2 + NAD(P)+ = FMN + NAD(P)H. UniProtKB Q07923

Subunit structure

Homodimer By similarity. UniProtKB Q07923

Subcellular location

Cytoplasm. Nucleus Ref.2.

Ontologies

Keywords
   Cellular componentCytoplasm
Nucleus
   LigandFMN
Flavoprotein
NAD
NADP
   Molecular functionOxidoreductase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular componentcytosol

Inferred from direct assay. Source: GeneDB_Spombe

nucleus

Inferred from direct assay. Source: GeneDB_Spombe

   Molecular functionFMN reductase activity

Inferred from sequence or structural similarity. Source: GeneDB_Spombe

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 200200NAD(P)H-dependent FMN reductase C4B3.06c
PRO_0000315910

Regions

Region96 – 994FMN binding By similarity UniProtKB Q07923

Sites

Binding site221FMN By similarity UniProtKB Q07923
Binding site1261FMN By similarity UniProtKB Q07923

Sequences

Sequence LengthMass (Da)Tools
Q9USJ6 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: D9552E192A940C98

FASTA20022,125
        10         20         30         40         50         60 
MTLPEKLLKI TPKILVIMGS VRSKRLCPTI ATWVGEMGKR ETNFDYEKVD LTDWPLSMSD 

        70         80         90        100        110        120 
EPGLPIMGID VYTQEHTKAW GSKIAGADGF VFVTPQYNGG YPAILKNALD HLYHEWNGKP 

       130        140        150        160        170        180 
LLIVSYGGHG GGDCASQLKH VAGFLKMRVA PTMPALTLPR DKIVQGVVDP AVEFTKHLGE 

       190        200 
LKKAFGEFSQ LFESNPERKP 

« Hide

References

[1]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed: 11859360] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.
[2]"ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
Nat. Biotechnol. 24:841-847(2006) [PubMed: 16823372] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU329672 Genomic DNA. Translation: CAB60680.1.
PIRT50442.
RefSeqNP_588084.1. NM_001023076.1.

3D structure databases

ProteinModelPortalQ9USJ6.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPCC4B3.06c.1; SPCC4B3.06c.1:pep; SPCC4B3.06c.
GeneID2538718.
KEGGspo:SPCC4B3.06c.
NMPDRfig|4896.1.peg.422.

Organism-specific databases

GeneDB_SpombeSPCC4B3.06c.

Phylogenomic databases

eggNOGfuNOG11552.
GeneTreeEFGT00050000002003.
HOGENOMHBG697130.
OMAEYNHSIS.
OrthoDBEOG4DJP65.

Gene expression databases

ArrayExpressQ9USJ6.

Family and domain databases

InterProIPR005025. FMN_red.
[Graphical view]
PfamPF03358. FMN_red. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFMNR_SCHPO
AccessionPrimary (citable) accession number: Q9USJ6
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 1, 2000
Last modified: December 14, 2011
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names