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Protein

Probable 1-aminocyclopropane-1-carboxylate deaminase

Gene

SPAC922.03

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate.By similarity

Catalytic activityi

1-aminocyclopropane-1-carboxylate + H2O = 2-oxobutanoate + NH3.

Cofactori

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei78NucleophileBy similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Pyridoxal phosphate

Names & Taxonomyi

Protein namesi
Recommended name:
Probable 1-aminocyclopropane-1-carboxylate deaminase (EC:3.5.99.7)
Short name:
ACC deaminase
Short name:
ACCD
Gene namesi
ORF Names:SPAC922.03
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC922.03.
PomBaseiSPAC922.03.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: GO_Central
  • cytosol Source: PomBase
  • nucleus Source: PomBase
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001845111 – 338Probable 1-aminocyclopropane-1-carboxylate deaminaseAdd BLAST338

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei51N6-(pyridoxal phosphate)lysineBy similarity1

Proteomic databases

MaxQBiQ9URX3.
PRIDEiQ9URX3.

Interactioni

Protein-protein interaction databases

BioGridi279980. 1 interactor.
MINTiMINT-4707153.

Structurei

3D structure databases

ProteinModelPortaliQ9URX3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000022460.
InParanoidiQ9URX3.
KOiK01505.
OMAiDWEDPGY.
OrthoDBiEOG092C3SFI.
PhylomeDBiQ9URX3.

Family and domain databases

InterProiIPR027278. ACCD_DCysDesulf.
IPR005965. ACP_carboxylate_deaminase.
IPR001926. TrpB-like_PLP-dep.
[Graphical view]
PfamiPF00291. PALP. 1 hit.
[Graphical view]
PIRSFiPIRSF006278. ACCD_DCysDesulf. 1 hit.
SUPFAMiSSF53686. SSF53686. 1 hit.
TIGRFAMsiTIGR01274. ACC_deam. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9URX3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLEQFKKYP LTFGPTPITS MKRLSKTLGG KVEIFAKRED CNSGLAFGGN
60 70 80 90 100
KIRKLEYLIP EAIDGGYDTL VSIGGIQSNQ TRQVAAVAAH LGLDCVLIQE
110 120 130 140 150
DWVDYKDTMY DRVGNIELSR IVNADVRLDS SKFDIGIRPS FKNALEELTK
160 170 180 190 200
KGKKPFPIPA GCSEHPYGGL GFVGCVEEIY EQEKQLGFKF DKIVVCTVTG
210 220 230 240 250
SSFAGIIVGM ALTGRQKDVI GIDASATPEK TKAQVLRIAQ NTAKLIGLEK
260 270 280 290 300
ELTESDVNID TRFAHPAYGI PNEGTIEAIK LCGATEGVLT DPVYEGKSMQ
310 320 330
GLIHLVRNNE IAEGSKVLYI HLGGAPALSA YSAYFKNT
Length:338
Mass (Da):36,687
Last modified:May 1, 2000 - v1
Checksum:iAE480741BD708BF3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB63550.1.
PIRiT50268.
RefSeqiNP_595003.1. NM_001020434.2.

Genome annotation databases

EnsemblFungiiSPAC922.03.1; SPAC922.03.1:pep; SPAC922.03.
GeneIDi2543564.
KEGGispo:SPAC922.03.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB63550.1.
PIRiT50268.
RefSeqiNP_595003.1. NM_001020434.2.

3D structure databases

ProteinModelPortaliQ9URX3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi279980. 1 interactor.
MINTiMINT-4707153.

Proteomic databases

MaxQBiQ9URX3.
PRIDEiQ9URX3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC922.03.1; SPAC922.03.1:pep; SPAC922.03.
GeneIDi2543564.
KEGGispo:SPAC922.03.

Organism-specific databases

EuPathDBiFungiDB:SPAC922.03.
PomBaseiSPAC922.03.

Phylogenomic databases

HOGENOMiHOG000022460.
InParanoidiQ9URX3.
KOiK01505.
OMAiDWEDPGY.
OrthoDBiEOG092C3SFI.
PhylomeDBiQ9URX3.

Miscellaneous databases

PROiQ9URX3.

Family and domain databases

InterProiIPR027278. ACCD_DCysDesulf.
IPR005965. ACP_carboxylate_deaminase.
IPR001926. TrpB-like_PLP-dep.
[Graphical view]
PfamiPF00291. PALP. 1 hit.
[Graphical view]
PIRSFiPIRSF006278. ACCD_DCysDesulf. 1 hit.
SUPFAMiSSF53686. SSF53686. 1 hit.
TIGRFAMsiTIGR01274. ACC_deam. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry namei1A1D_SCHPO
AccessioniPrimary (citable) accession number: Q9URX3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: May 1, 2000
Last modified: October 5, 2016
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.