ID   YBL3_SCHPO              Reviewed;         357 AA.
AC   Q9URV8;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   27-MAR-2024, entry version 107.
DE   RecName: Full=UPF0744 protein C106.03;
GN   ORFNames=SPBC106.03;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
RN   [3]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-282, AND IDENTIFICATION BY
RP   MASS SPECTROMETRY.
RX   PubMed=18257517; DOI=10.1021/pr7006335;
RA   Wilson-Grady J.T., Villen J., Gygi S.P.;
RT   "Phosphoproteome analysis of fission yeast.";
RL   J. Proteome Res. 7:1088-1097(2008).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the UPF0744 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CU329671; CAB53719.1; -; Genomic_DNA.
DR   PIR; T39260; T39260.
DR   RefSeq; NP_595152.1; NM_001021061.2.
DR   AlphaFoldDB; Q9URV8; -.
DR   SMR; Q9URV8; -.
DR   BioGRID; 276587; 2.
DR   STRING; 284812.Q9URV8; -.
DR   iPTMnet; Q9URV8; -.
DR   MaxQB; Q9URV8; -.
DR   PaxDb; 4896-SPBC106-03-1; -.
DR   EnsemblFungi; SPBC106.03.1; SPBC106.03.1:pep; SPBC106.03.
DR   GeneID; 2540049; -.
DR   KEGG; spo:SPBC106.03; -.
DR   PomBase; SPBC106.03; -.
DR   VEuPathDB; FungiDB:SPBC106.03; -.
DR   eggNOG; ENOG502QWSS; Eukaryota.
DR   HOGENOM; CLU_776491_0_0_1; -.
DR   InParanoid; Q9URV8; -.
DR   OMA; SYYKRYD; -.
DR   PhylomeDB; Q9URV8; -.
DR   Reactome; R-SPO-193144; Estrogen biosynthesis.
DR   Reactome; R-SPO-194002; Glucocorticoid biosynthesis.
DR   Reactome; R-SPO-5365859; RA biosynthesis pathway.
DR   Reactome; R-SPO-77108; Utilization of Ketone Bodies.
DR   Reactome; R-SPO-77111; Synthesis of Ketone Bodies.
DR   Reactome; R-SPO-9757110; Prednisone ADME.
DR   PRO; PR:Q9URV8; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR   GO; GO:0005739; C:mitochondrion; ISO:PomBase.
DR   GO; GO:0016491; F:oxidoreductase activity; IBA:GO_Central.
DR   GO; GO:0016229; F:steroid dehydrogenase activity; ISO:PomBase.
DR   GO; GO:0008202; P:steroid metabolic process; IBA:GO_Central.
DR   InterPro; IPR013952; DUF1776_fun.
DR   PANTHER; PTHR43313:SF1; DEHYDROGENASES, SHORT CHAIN; 1.
DR   PANTHER; PTHR43313; SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C; 1.
DR   Pfam; PF08643; DUF1776; 2.
PE   1: Evidence at protein level;
KW   Cytoplasm; Phosphoprotein; Reference proteome.
FT   CHAIN           1..357
FT                   /note="UPF0744 protein C106.03"
FT                   /id="PRO_0000374008"
FT   MOD_RES         282
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:18257517"
SQ   SEQUENCE   357 AA;  40006 MW;  D39912DF4112A556 CRC64;
     MNPERWAADL VSNVKDYGKR IIDYAHEKTS NPQPVTVHTT NSAKGRLGEF LYQNRVSVGL
     GSAALFLAGL SYYKRYDYVR KRRAPRAPNH QKTQVVVLSA WNPLASVIAH DLDRRGFIVV
     VLVRDASEAA TVSLQQRPYI QSLIVTHNEA VERFLLSFSN QSGPKEYALR LRGLILVPTG
     DSLYTPIENI GKDAWISAFQ QLSESFSNVS RMIPLLKSQK ARIIGLSHGI LSAYEPPNYA
     VPSILSSSIE TFLRTLKRET GLQVICIKLG NLSFLNYDHS SSPGKSNYPP SLCTERKVLN
     KIFDSLLGCW PSPTRHVGCR TFFMVTVSRF LPTCVIDGIF SLFGKFHFFS CSLIKRS
//