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Protein
Submitted name:

Glucocerebrosidase

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Biological processi

  1. regulation of water loss via skin Source: Ensembl
  2. response to estrogen Source: Ensembl
  3. response to glucocorticoid Source: Ensembl
  4. response to pH Source: Ensembl
  5. response to testosterone Source: Ensembl
  6. response to thyroid hormone Source: Ensembl
  7. skin morphogenesis Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
GlucocerebrosidaseImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. lysosomal lumen Source: Ensembl
  2. lysosomal membrane Source: Ensembl
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919 PotentialImportedAdd
BLAST
Chaini20 – ›25›6 PotentialImportedPRO_5000143105

Expressioni

Gene expression databases

BgeeiQ9UQU9.
ExpressionAtlasiQ9UQU9. baseline and differential.

Family & Domainsi

Keywords - Domaini

SignalImported

Sequencei

Sequence statusi: Fragment.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9UQU9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20 
MAGSLTGLLL LQAVSWASGA RPCIP
Length:25
Mass (Da):2,513
Last modified:April 30, 2000 - v1
Checksum:i87F617CA838FE67C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei25 – 251Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M20248 Genomic DNA. Translation: AAA35875.1.
UniGeneiHs.282997.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M20248 Genomic DNA. Translation: AAA35875.1.
UniGeneiHs.282997.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Gene expression databases

BgeeiQ9UQU9.
ExpressionAtlasiQ9UQU9. baseline and differential.

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "The human glucocerebrosidase gene has two functional ATG initiator codons."
    Sorge J.A., West C., Kuhl W., Treger L., Beutler E.
    Am. J. Hum. Genet. 41:1016-1024(1986) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ9UQU9_HUMAN
AccessioniPrimary (citable) accession number: Q9UQU9
Entry historyi
Integrated into UniProtKB/TrEMBL: April 30, 2000
Last sequence update: April 30, 2000
Last modified: November 25, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.