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Q9UQ98 (Q9UQ98_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Name:MRP EMBL AAB83982.1
OrganismHomo sapiens (Human) EMBL AAB83982.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length1400 AA.
Sequence statusFragment.
Protein existenceInferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the ABC transporter superfamily. RuleBase RU000684

Contains ABC transmembrane type-1 domains. SAAS SAAS011527

Contains ABC transmembrane type-domains. SAAS SAAS011527

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL AAB83982.1

Sequences

Sequence LengthMass (Da)Tools
Q9UQ98 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: C7C4DBB78DADDAAA

FASTA1,400157,211
        10         20         30         40         50         60 
DWNVTWNTSN PDFTKCFQNT VLVWVPCFYL WACFPFYFLY LSRHDRGYIQ MTPLNKTKTA 

        70         80         90        100        110        120 
LGFLLWIVCW ADLFYSFWER SRGIFLAPVF LVSPTLLGIT TLLATFLIQL ERRKGVQSSG 

       130        140        150        160        170        180 
IMLTFWLVAL VCALAILRSK IMTALKEDAQ VDLFRDITFY VYFSLLLIQL VLSCFSDRSP 

       190        200        210        220        230        240 
LFSETIHDPN PCPESSASFL SRITFWWITG LIVRGYRQPL EGSDLWSLNK EDTSEQVVPV 

       250        260        270        280        290        300 
LVKNWKKECA KTRKQPVKVV YSSKDPAQPK ESSKVDANEE VEALIVKSPQ KEWNPSLFKV 

       310        320        330        340        350        360 
LYKTFGPYFL MSFFFKAIHD LMMFSGPQIL KLLIKFVNDT KAPDWQGYFY TVLLFVTACL 

       370        380        390        400        410        420 
QTLVLHQYFH ICFVSGMRIK TAVIGAVYRK ALVITNSARK SSTVGEIVNL MSVDAQRFMD 

       430        440        450        460        470        480 
LATYINMIWS APLQVILALY LLWLNLGPSV LAGVAVMVLM VPVNAVMAMK TKTYQVAHMK 

       490        500        510        520        530        540 
SKDNRIKLMN EILNGIKVLK LYAWELAFKD KVLAIRQEEL KVLKKSAYLS AVGTFTWVCT 

       550        560        570        580        590        600 
PFLVALCTFA VYVTIDENNI LDAQTAFVSL ALFNILRFPL NILPMVISSI VQASVSLKRL 

       610        620        630        640        650        660 
RIFLSHEELE PDSIERRPVK DGGGTNSITV RNATFTWARS DPPTLNGITF SIPEGALVAV 

       670        680        690        700        710        720 
VGQVGCGKSS LLSALLAEMD KVEGHVAIKT RILVTHSMSY LPQVDVIIVM SGGKISEMGS 

       730        740        750        760        770        780 
YQELLARDGA FAEFLRTYAS TEQEQDAEEN GVTGVSGPGK EAKQMENGML VTDSAGKQLQ 

       790        800        810        820        830        840 
RQLSSSSSYS GDISRHHNST AELQKAEAKK EETWKLMEAD KAQTGQVKLS VYWDYMKAIG 

       850        860        870        880        890        900 
LFISFLSIFL FMCNHVSALA SNYWLSLWTD DPIVNGTQEH TKVRLSVYGA LGISQGIAVF 

       910        920        930        940        950        960 
GYSMAVSIGG ILASRCLHVD LLHSILRSPM SFFERTPSGN LVNRFSKELD TVDSMIPEVI 

       970        980        990       1000       1010       1020 
KMFMGSLFNV IGACIVILLA TPIAAIIIPP LGLIYFFVQR FYVASSRQLK RLESVSRSPV 

      1030       1040       1050       1060       1070       1080 
YSHFNETLLG VSVIRAFEEQ ERFIHQSDLK VDENQKAYYP SIVANRWLAV RLECVGNCIV 

      1090       1100       1110       1120       1130       1140 
LFAALFAVIS RHSLSAGLVG LSVSYSLQVT TYLNWLVRMS SEMETNIVAV ERLKEYSETE 

      1150       1160       1170       1180       1190       1200 
KEAPWQIQET APPSSWPQVG RVEFRNYCLR YREDLDFVLR HINVTINGGE KVGIVGRTGA 

      1210       1220       1230       1240       1250       1260 
GKSSLTLGLF RINESAEGEI IIDGINIAKI GLHDLRFKIT IIPQDPVLFS GSLRMNLDPF 

      1270       1280       1290       1300       1310       1320 
SQYSDEEVWT SLELAHLKDF VSALPDKLDH ECAEGGENLS VGQRQLVCLA RALLRKTKIL 

      1330       1340       1350       1360       1370       1380 
VLDEATAAVD LETDDLIQST IRTQFEDCTV LTIAHRLNTI MDYTRVIVLD KGEIQEYGAP 

      1390       1400 
SDLLQQRGLF YSMAKDAGLV 

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References

[1]"Analysis of the intron-exon organization of the human multidrug-resistance protein gene (MRP) and alternative splicing of its mRNA."
Grant C.E., Kurz E.U., Cole S.P.C., Deeley R.G.
Genomics 45:368-378(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF022853 expand/collapse EMBL AC list , AF022824, AF022825, AF022826, AF022827, AF022828, AF022829, AF022830, AF022831, AF022832, AF022833, AF022834, AF022835, AF022836, AF022837, AF022838, AF022841, AF022842, AF022843, AF022844, AF022845, AF022846, AF022847, AF022848, AF022849, AF022850, AF022851, AF022852 Genomic DNA. Translation: AAB83982.1.
UniGeneHs.391464.

3D structure databases

ProteinModelPortalQ9UQ98.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ9UQ98.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG108314.

Family and domain databases

Gene3D3.40.50.300. 3 hits.
InterProIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR001140. ABC_transptr_TM_dom.
IPR005292. Multidrug-R_assoc.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF00664. ABC_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
[Graphical view]
SMARTSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMSSF52540. SSF52540. 2 hits.
SSF90123. SSF90123. 2 hits.
TIGRFAMsTIGR00957. MRP_assoc_pro. 1 hit.
PROSITEPS50929. ABC_TM1F. 2 hits.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ9UQ98_HUMAN
AccessionPrimary (citable) accession number: Q9UQ98
Entry history
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: April 16, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.