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Q9UQ07

- MOK_HUMAN

UniProt

Q9UQ07 - MOK_HUMAN

Protein

MAPK/MAK/MRK overlapping kinase

Gene

MOK

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 125 (01 Oct 2014)
      Sequence version 1 (01 May 2000)
      Previous versions | rss
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    Functioni

    Able to phosphorylate several exogenous substrates and to undergo autophosphorylation.By similarity

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.

    Enzyme regulationi

    Phosphorylation appears to increase the enzymatic activity.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei33 – 331ATPPROSITE-ProRule annotation
    Active sitei128 – 1281Proton acceptorPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi10 – 189ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. cyclin-dependent protein serine/threonine kinase activity Source: UniProtKB-EC
    3. protein kinase activity Source: ProtInc
    4. protein serine/threonine kinase activity Source: ProtInc

    GO - Biological processi

    1. protein phosphorylation Source: ProtInc
    2. signal transduction Source: ProtInc

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    SignaLinkiQ9UQ07.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    MAPK/MAK/MRK overlapping kinase (EC:2.7.11.22)
    Alternative name(s):
    MOK protein kinase
    Renal tumor antigen 1
    Short name:
    RAGE-1
    Gene namesi
    Name:MOK
    Synonyms:RAGE, RAGE1
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 14

    Organism-specific databases

    HGNCiHGNC:9833. MOK.

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: ProtInc

    Keywords - Cellular componenti

    Cytoplasm

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA34187.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 419419MAPK/MAK/MRK overlapping kinasePRO_0000086341Add
    BLAST

    Post-translational modificationi

    Autophosphorylated.By similarity

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    PaxDbiQ9UQ07.
    PRIDEiQ9UQ07.

    PTM databases

    PhosphoSiteiQ9UQ07.

    Expressioni

    Tissue specificityi

    Expressed in heart, brain, lung, kidney, and pancreas, and at very low levels in placenta, liver and skeletal muscle. Detected in retina.

    Gene expression databases

    ArrayExpressiQ9UQ07.
    BgeeiQ9UQ07.
    CleanExiHS_RAGE.
    GenevestigatoriQ9UQ07.

    Organism-specific databases

    HPAiHPA027282.
    HPA027292.

    Interactioni

    Protein-protein interaction databases

    BioGridi111828. 8 interactions.
    IntActiQ9UQ07. 4 interactions.
    MINTiMINT-4777240.
    STRINGi9606.ENSP00000355304.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9UQ07.
    SMRiQ9UQ07. Positions 1-328.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini4 – 285282Protein kinasePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0515.
    HOGENOMiHOG000233024.
    HOVERGENiHBG106271.
    KOiK08830.
    OMAiYLCVCPS.
    PhylomeDBiQ9UQ07.
    TreeFamiTF328769.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF00069. Pkinase. 1 hit.
    [Graphical view]
    SMARTiSM00220. S_TKc. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequences (6)i

    Sequence statusi: Complete.

    This entry describes 6 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q9UQ07-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MKNYKAIGKI GEGTFSEVMK MQSLRDGNYY ACKQMKQRFE SIEQVNNLRE    50
    IQALRRLNPH PNILMLHEVV FDRKSGSLAL ICELMDMNIY ELIRGRRYPL 100
    SEKKIMHYMY QLCKSLDHIH RNGIFHRDVK PENILIKQDV LKLGDFGSCR 150
    SVYSKQPYTE YISTRWYRAP ECLLTDGFYT YKMDLWSAGC VFYEIASLQP 200
    LFPGVNELDQ ISKIHDVIGT PAQKILTKFK QSRAMNFDFP FKKGSGIPLL 250
    TTNLSPQCLS LLHAMVAYDP DERIAAHQAL QHPYFQEQRK TEKRALGSHR 300
    KAGFPEHPVA PEPLSNSCQI SKEGRKQKQS LKQEEDRPKR RGPAYVMELP 350
    KLKLSGVVRL SSYSSPTLQS VLGSGTNGRV PVLRPLKCIP ASKKTDPQKD 400
    LKPAPQQCRL PTIVRKGGR 419
    Length:419
    Mass (Da):48,014
    Last modified:May 1, 2000 - v1
    Checksum:iCDA7D9C1E80AAE8F
    GO
    Isoform 2 (identifier: Q9UQ07-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         232-419: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:231
    Mass (Da):27,120
    Checksum:iD0665FAE077D3B76
    GO
    Isoform 3 (identifier: Q9UQ07-3) [UniParc]FASTAAdd to Basket

    Also known as: RAGE-1 ORF5, RAGE-2 ORF5, RAGE-3 ORF5

    The sequence of this isoform differs from the canonical sequence as follows:
         1-346: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:73
    Mass (Da):7,879
    Checksum:i38B1376ECFEDF351
    GO
    Isoform 4 (identifier: Q9UQ07-4) [UniParc]FASTAAdd to Basket

    Also known as: RAGE-4 ORF3

    The sequence of this isoform differs from the canonical sequence as follows:
         1-234: Missing.
         290-329: KTEKRALGSH...ISKEGRKQKQ → TQNGSEDEAS...LPGRSVTLLV
         330-419: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:95
    Mass (Da):10,482
    Checksum:i8B155074ED025D9A
    GO
    Isoform 5 (identifier: Q9UQ07-5) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         42-71: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:389
    Mass (Da):44,425
    Checksum:i72B60D201632301B
    GO
    Isoform 6 (identifier: Q9UQ07-6) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         138-138: Missing.

    Note: Gene prediction based on EST data.

    Show »
    Length:418
    Mass (Da):47,886
    Checksum:i75769950EB76F3F7
    GO

    Sequence cautioni

    The sequence AAB38087.1 differs from that shown. Reason: Frameshift at position 299.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti269 – 2691D → G in BAG35641. (PubMed:14702039)Curated
    Sequence conflicti313 – 3131P → L in BAG35641. (PubMed:14702039)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti38 – 381R → H.1 Publication
    Corresponds to variant rs34114580 [ dbSNP | Ensembl ].
    VAR_042011
    Natural varianti86 – 861D → N.1 Publication
    Corresponds to variant rs34084056 [ dbSNP | Ensembl ].
    VAR_042012
    Natural varianti217 – 2171V → I.1 Publication
    Corresponds to variant rs148360666 [ dbSNP | Ensembl ].
    VAR_070930
    Natural varianti230 – 2301K → R.1 Publication
    Corresponds to variant rs34965156 [ dbSNP | Ensembl ].
    VAR_042013
    Natural varianti248 – 2481P → S.1 Publication
    Corresponds to variant rs34299975 [ dbSNP | Ensembl ].
    VAR_042014
    Natural varianti272 – 2721E → D in a breast pleomorphic lobular carcinoma sample; somatic mutation. 1 Publication
    VAR_042015
    Natural varianti398 – 3981Q → R.1 Publication
    Corresponds to variant rs2236493 [ dbSNP | Ensembl ].
    VAR_024576

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 346346Missing in isoform 3. 1 PublicationVSP_009143Add
    BLAST
    Alternative sequencei1 – 234234Missing in isoform 4. 1 PublicationVSP_009142Add
    BLAST
    Alternative sequencei42 – 7130Missing in isoform 5. 1 PublicationVSP_054734Add
    BLAST
    Alternative sequencei138 – 1381Missing in isoform 6. CuratedVSP_054735
    Alternative sequencei232 – 419188Missing in isoform 2. 1 PublicationVSP_009144Add
    BLAST
    Alternative sequencei290 – 32940KTEKR…RKQKQ → TQNGSEDEASAVLLPIQTRS SLNPLLSTCMLPGRSVTLLV in isoform 4. 1 PublicationVSP_009145Add
    BLAST
    Alternative sequencei330 – 41990Missing in isoform 4. 1 PublicationVSP_009146Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB022694 mRNA. Translation: BAA81688.1.
    U46191 mRNA. Translation: AAB38079.1.
    U46192 mRNA. Translation: AAB38082.1.
    U46193 mRNA. Translation: AAB38085.1.
    U46194 mRNA. Translation: AAB38087.1. Frameshift.
    AK302349 mRNA. Translation: BAH13682.1.
    AK312778 mRNA. Translation: BAG35641.1.
    AL352978 Genomic DNA. No translation available.
    AL359402 Genomic DNA. No translation available.
    BC053536 mRNA. Translation: AAH53536.1.
    CCDSiCCDS61552.1. [Q9UQ07-5]
    CCDS9971.1. [Q9UQ07-1]
    RefSeqiNP_001258940.1. NM_001272011.1. [Q9UQ07-5]
    NP_055041.1. NM_014226.2. [Q9UQ07-1]
    UniGeneiHs.104119.

    Genome annotation databases

    EnsembliENST00000193029; ENSP00000193029; ENSG00000080823. [Q9UQ07-4]
    ENST00000361847; ENSP00000355304; ENSG00000080823. [Q9UQ07-1]
    ENST00000522874; ENSP00000429469; ENSG00000080823. [Q9UQ07-6]
    ENST00000524214; ENSP00000428942; ENSG00000080823. [Q9UQ07-5]
    GeneIDi5891.
    KEGGihsa:5891.
    UCSCiuc001ylm.4. human. [Q9UQ07-1]

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB022694 mRNA. Translation: BAA81688.1 .
    U46191 mRNA. Translation: AAB38079.1 .
    U46192 mRNA. Translation: AAB38082.1 .
    U46193 mRNA. Translation: AAB38085.1 .
    U46194 mRNA. Translation: AAB38087.1 . Frameshift.
    AK302349 mRNA. Translation: BAH13682.1 .
    AK312778 mRNA. Translation: BAG35641.1 .
    AL352978 Genomic DNA. No translation available.
    AL359402 Genomic DNA. No translation available.
    BC053536 mRNA. Translation: AAH53536.1 .
    CCDSi CCDS61552.1. [Q9UQ07-5 ]
    CCDS9971.1. [Q9UQ07-1 ]
    RefSeqi NP_001258940.1. NM_001272011.1. [Q9UQ07-5 ]
    NP_055041.1. NM_014226.2. [Q9UQ07-1 ]
    UniGenei Hs.104119.

    3D structure databases

    ProteinModelPortali Q9UQ07.
    SMRi Q9UQ07. Positions 1-328.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 111828. 8 interactions.
    IntActi Q9UQ07. 4 interactions.
    MINTi MINT-4777240.
    STRINGi 9606.ENSP00000355304.

    PTM databases

    PhosphoSitei Q9UQ07.

    Proteomic databases

    PaxDbi Q9UQ07.
    PRIDEi Q9UQ07.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000193029 ; ENSP00000193029 ; ENSG00000080823 . [Q9UQ07-4 ]
    ENST00000361847 ; ENSP00000355304 ; ENSG00000080823 . [Q9UQ07-1 ]
    ENST00000522874 ; ENSP00000429469 ; ENSG00000080823 . [Q9UQ07-6 ]
    ENST00000524214 ; ENSP00000428942 ; ENSG00000080823 . [Q9UQ07-5 ]
    GeneIDi 5891.
    KEGGi hsa:5891.
    UCSCi uc001ylm.4. human. [Q9UQ07-1 ]

    Organism-specific databases

    CTDi 5891.
    GeneCardsi GC14M102690.
    H-InvDB HIX0011985.
    HGNCi HGNC:9833. MOK.
    HPAi HPA027282.
    HPA027292.
    MIMi 605762. gene.
    neXtProti NX_Q9UQ07.
    PharmGKBi PA34187.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG0515.
    HOGENOMi HOG000233024.
    HOVERGENi HBG106271.
    KOi K08830.
    OMAi YLCVCPS.
    PhylomeDBi Q9UQ07.
    TreeFami TF328769.

    Enzyme and pathway databases

    SignaLinki Q9UQ07.

    Miscellaneous databases

    ChiTaRSi MOK. human.
    GeneWikii RAGE_(gene).
    GenomeRNAii 5891.
    NextBioi 22916.
    PROi Q9UQ07.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q9UQ07.
    Bgeei Q9UQ07.
    CleanExi HS_RAGE.
    Genevestigatori Q9UQ07.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SMARTi SM00220. S_TKc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Molecular cloning and characterization of a novel member of the MAP kinase superfamily."
      Miyata Y., Akashi M., Nishida E.
      Genes Cells 4:299-309(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
      Tissue: Fetal brain.
    2. "A new gene coding for an antigen recognized by autologous cytolytic T lymphocytes on a human renal carcinoma."
      Gaugler B., Brouwenstijn N., Vantomme V., Szikora J.-P., Van der Spek C.W., Patard J.-J., Boon T., Schrier P., Van den Eynde B.J.
      Immunogenetics 44:323-330(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 3 AND 4).
      Tissue: Renal cell carcinoma.
    3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 5), VARIANT ILE-217.
      Tissue: Testis.
    4. "The DNA sequence and analysis of human chromosome 14."
      Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C., Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A., Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S., Sun H., Du H.
      , Pepin K., Artiguenave F., Robert C., Cruaud C., Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P., Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N., Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C., Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S., Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B., Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M., Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S., Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D., Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A., Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M., Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V., Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L., Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J., Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W., Quetier F., Waterston R., Hood L., Weissenbach J.
      Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
      Tissue: Brain, Lung and Testis.
    6. "Patterns of somatic mutation in human cancer genomes."
      Greenman C., Stephens P., Smith R., Dalgliesh G.L., Hunter C., Bignell G., Davies H., Teague J., Butler A., Stevens C., Edkins S., O'Meara S., Vastrik I., Schmidt E.E., Avis T., Barthorpe S., Bhamra G., Buck G.
      , Choudhury B., Clements J., Cole J., Dicks E., Forbes S., Gray K., Halliday K., Harrison R., Hills K., Hinton J., Jenkinson A., Jones D., Menzies A., Mironenko T., Perry J., Raine K., Richardson D., Shepherd R., Small A., Tofts C., Varian J., Webb T., West S., Widaa S., Yates A., Cahill D.P., Louis D.N., Goldstraw P., Nicholson A.G., Brasseur F., Looijenga L., Weber B.L., Chiew Y.-E., DeFazio A., Greaves M.F., Green A.R., Campbell P., Birney E., Easton D.F., Chenevix-Trench G., Tan M.-H., Khoo S.K., Teh B.T., Yuen S.T., Leung S.Y., Wooster R., Futreal P.A., Stratton M.R.
      Nature 446:153-158(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: VARIANTS [LARGE SCALE ANALYSIS] HIS-38; ASN-86; ARG-230; SER-248; ASP-272 AND ARG-398.

    Entry informationi

    Entry nameiMOK_HUMAN
    AccessioniPrimary (citable) accession number: Q9UQ07
    Secondary accession number(s): B2R6Z4
    , B7Z7P6, E7ER76, E7ERR8, Q92790, Q93067
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 16, 2004
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 125 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 14
      Human chromosome 14: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. Human and mouse protein kinases
      Human and mouse protein kinases: classification and index
    6. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3