ID   ZN409_HUMAN             Reviewed;         862 AA.
AC   Q9UPU6;
DT   12-FEB-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   13-OCT-2009, entry version 61.
DE   RecName: Full=Zinc finger protein 409;
GN   Name=ZNF409; Synonyms=KIAA1056;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   MEDLINE=99397452; PubMed=10470851; DOI=10.1093/dnares/6.3.197;
RA   Kikuno R., Nagase T., Ishikawa K., Hirosawa M., Miyajima N.,
RA   Tanaka A., Kotani H., Nomura N., Ohara O.;
RT   "Prediction of the coding sequences of unidentified human genes. XIV.
RT   The complete sequences of 100 new cDNA clones from brain which code
RT   for large proteins in vitro.";
RL   DNA Res. 6:197-205(1999).
CC   -!- FUNCTION: May be involved in transcriptional regulation.
CC   -!- SUBCELLULAR LOCATION: Nucleus (Probable).
CC   -!- SIMILARITY: Contains 6 C2H2-type zinc fingers.
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DR   EMBL; AB028979; BAA83008.2; ALT_INIT; mRNA.
DR   IPI; IPI00007109; -.
DR   UniGene; Hs.508937; -.
DR   HSSP; P15822; 3ZNF.
DR   PhosphoSite; Q9UPU6; -.
DR   PRIDE; Q9UPU6; -.
DR   Ensembl; ENST00000258869; ENSP00000258869; ENSG00000136367; Homo sapiens.
DR   Ensembl; ENST00000382785; ENSP00000372235; ENSG00000136367; Homo sapiens.
DR   Ensembl; ENST00000412565; ENSP00000409464; ENSG00000136367; Homo sapiens.
DR   Ensembl; ENST00000419474; ENSP00000413418; ENSG00000136367; Homo sapiens.
DR   UCSC; uc001wkf.1; human.
DR   GeneCards; GC14M023069; -.
DR   GeneCards; GC14U900909; -.
DR   HGNC; HGNC:20042; ZNF409.
DR   HPA; HPA005146; -.
DR   PharmGKB; PA142670520; -.
DR   Bgee; Q9UPU6; -.
DR   CleanEx; HS_ZNF409; -.
DR   Genevestigator; Q9UPU6; -.
DR   GermOnline; ENSG00000206083; Homo sapiens.
DR   GO; GO:0005737; C:cytoplasm; IDA:HPA.
DR   GO; GO:0005634; C:nucleus; IDA:HPA.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0045449; P:regulation of transcription; IEA:UniProtKB-KW.
DR   GO; GO:0006350; P:transcription; IEA:UniProtKB-KW.
DR   InterPro; IPR007087; Znf_C2H2.
DR   InterPro; IPR015880; Znf_C2H2-like.
DR   InterPro; IPR013087; Znf_C2H2/integrase_DNA-bd.
DR   Gene3D; G3DSA:3.30.160.60; Znf_C2H2/integrase_DNA-bd; 1.
DR   Pfam; PF00096; zf-C2H2; 2.
DR   SMART; SM00355; ZnF_C2H2; 6.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 2.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; FALSE_NEG.
PE   2: Evidence at transcript level;
KW   Complete proteome; DNA-binding; Metal-binding; Nucleus; Repeat;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN         1    862       Zinc finger protein 409.
FT                                /FTId=PRO_0000047570.
FT   ZN_FING     237    259       C2H2-type 1.
FT   ZN_FING     453    476       C2H2-type 2.
FT   ZN_FING     508    532       C2H2-type 3.
FT   ZN_FING     569    593       C2H2-type 4.
FT   ZN_FING     758    782       C2H2-type 5.
FT   ZN_FING     821    845       C2H2-type 6.
FT   COMPBIAS    605    710       Pro-rich.
SQ   SEQUENCE   862 AA;  91802 MW;  EB6BFF9A0B939217 CRC64;
     MATLNSASTT GTTPSPGHNA PSLPSDTFSS STPSDPVTKD PPAASSTSEN MRSSEPGGQL
     LESGCGLVPP KEIGEPQEGP DCGHFPPNDP GVEKDKEQEE EEEGLPPMDL SNHLFFTAGG
     EAYLVAKLSL PGGSELLLPK GFPWGEAGIK EEPSLPFLAY PPPSHLTALH IQHGFDPIQG
     FSSSDQILSH DTSAPSPAAC EERHGAFWSY QLAPNPPGDP KDGPMGNSGG NHVAVFWLCL
     LCRLGFSKPQ AFMDHTQSHG VKLTPAQYQG LSGSPAVLQE GDEGCKALIS FLEPKLPARP
     SSDIPLDNSS TVNMEANVAQ TEDGPPEAEV QALILLDEEV MALSPPSPPT ATWDPSPTQA
     KESPVAAGEA GPDWFPEGQE EDGGLCPPLN QSSPTSKEGG TLPAPVGSPE DPSDPPQPYR
     LADDYTPAPA AFQGLSLSSH MSLLHSRNSC KTLKCPKCNW HYKYQQTLDV HMQEKHPESN
     SHCSYCSAGG AHPRLARGES YNCGYKPYRC DVCNYSTTTK GNLSIHMQSD KHLANLQGFQ
     AGPGGQGSPT EASLPPSAGD KEPKTKSSWQ CKVCSYETNI SRNLRIHMTS EKHMQNVLML
     HQGLPLGLPP GLMGPGPPPP PGATPTSPPE LFQYFGPQAL GQPQTPLAGP GLRPDKPLEA
     QLLLNGFHHV GAPARKFPTS APGSLSPDAH LPPSQLLGSS SDSLPTSPPP DDSLSLKVFR
     CLVCQAFSTD SLELLLYHCS IGRSLPEAEW KEVAGDTHRC KLCCYGTQLK ANFQLHLKTD
     KHAQKYQLAA HLREGGGAMG TPSPASLGDG APYGSVSPLH LRCNICDFES NSKEKMQLHA
     RGAAHEENSQ IYKRTETGLL IK
//