Q9UPS8 (ANR26_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ankyrin repeat domain-containing protein 26

Gene names

Name:	ANKRD26
Synonyms:	KIAA1074

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1709 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities	Contains 5 ANK repeats.
Sequence caution	The sequence BAA83026.2 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing Polymorphism
Domain	ANK repeat Coiled coil Repeat
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	centrosome Inferred from direct assay PubMed 21399614. Source: UniProtKB
Complete GO annotation...

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q9UPS8-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q9UPS8-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-443: Missing.
     444-545: KEKNIGNEQA...REGSENNQPQ → MNHMFHIKRH...EKEKVQLQKE
     605-605: S → SS

Note: No experimental confirmation available.

Isoform 3 (identifier: Q9UPS8-3)

The sequence of this isoform differs from the canonical sequence as follows:
     605-605: S → SS

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1709	1709	Ankyrin repeat domain-containing protein 26		PRO_0000240843
Regions
	Repeat	45 – 75	31	ANK 1
	Repeat	79 – 108	30	ANK 2
	Repeat	112 – 141	30	ANK 3
	Repeat	145 – 174	30	ANK 4
	Repeat	178 – 207	30	ANK 5
	Coiled coil	529 – 566	38	Potential
	Coiled coil	742 – 872	131	Potential
	Coiled coil	904 – 1471	568	Potential
	Coiled coil	1516 – 1586	71	Potential
	Coiled coil	1648 – 1673	26	Potential
	Compositional bias	25 – 28	4	Poly-Gly
	Compositional bias	574 – 579	6	Poly-Asp
Amino acid modifications
	Modified residue	241	1	Phosphoserine By similarity
Natural variations
	Alternative sequence	1 – 443	443	Missing in isoform 2.		VSP_019434
	Alternative sequence	444 – 545	102	KEKNI…NNQPQ → MNHMFHIKRHSISAGTDAYK KTKPIQNLFQKPLYDHCSAN NYKSMEPELENVRSSPPRGD RTSKVSLKEELQQDMQRFKN EIGMLKVEFQALEKEKVQLQ KE in isoform 2.		VSP_019435
	Alternative sequence	605	1	S → SS in isoform 2 and isoform 3.		VSP_021022
	Natural variant	20	1	Q → R. Ref.1 Ref.3 Corresponds to variant rs7897309 [ dbSNP | Ensembl ].		VAR_026833
	Natural variant	425	1	I → V. Corresponds to variant rs12359281 [ dbSNP | Ensembl ].		VAR_055513
	Natural variant	1219	1	V → L. Corresponds to variant rs12572862 [ dbSNP | Ensembl ].		VAR_055514
	Natural variant	1304	1	V → I. Ref.3 Corresponds to variant rs10829163 [ dbSNP | Ensembl ].		VAR_026834
	Natural variant	1513	1	F → L. Ref.3 Corresponds to variant rs2274741 [ dbSNP | Ensembl ].		VAR_026835
Experimental info
	Sequence conflict	1346	1	D → G in BAC87508. Ref.3
	Sequence conflict	1516 – 1522	7	NNFASMK → KQDLPDS in BAC87508. Ref.3

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified June 27, 2006. Version 3. Checksum: C01DDA23FA478E2D	FASTA	1,709	196,324
	10 20 30 40 50 60 MKKIFSKKGE SPLGSFARRQ RSSAGGGGEP GEGAYSQPGY HVRDRDLGKI HKAASAGNVA 70 80 90 100 110 120 KVQQILLLRK NGLNDRDKMN RTALHLACAN GHPEVVTLLV DRKCQLNVCD NENRTALMKA 130 140 150 160 170 180 VQCQEEKCAT ILLEHGADPN LADVHGNTAL HYAVYNEDIS VATKLLLYDA NIEAKNKDDL 190 200 210 220 230 240 TPLLLAVSGK KQQMVEFLIK KKANVNAVDK LESSHQLISE YKEERIPKHS SQNSNSVDES 250 260 270 280 290 300 SEDSLSRLSG KPGVDDSWPT SDDEDLNFDT KNVPKPSLAK LMTASQQSRK NLEATYGTVR 310 320 330 340 350 360 TGNRTLFEDR DSDSQDEVVV ESLPTTSIKV QCFSHPTYQS PDLLPKPSHK SLANPGLMKE 370 380 390 400 410 420 EPTKPGIAKK ENGIDIIESA PLEQTNNDNL TYVDEVHKNN RSDMMSALGL GQEEDIESPW 430 440 450 460 470 480 DSESISENFP QKYVDPLAGA ADGKEKNIGN EQAEDVFYIP SCMSGSRNFK MAKLEDTRNV 490 500 510 520 530 540 GMPVAHMESP ERYLHLKPTI EMKDSVPNKA GGMKDVQTSK AAEHDLEVAS EEEQEREGSE 550 560 570 580 590 600 NNQPQVEEER KKHRNNEMEV SANIHDGATD DAEDDDDDDG LIQKRKSGET DHQQFPRKEN 610 620 630 640 650 660 KEYASGPALQ MKEVKSTEKE KRTSKESVNS PVFGKASLLT GGLLQVDDDS SLSEIDEDEG 670 680 690 700 710 720 RPTKKTSNEK NKVKNQIQSM DDVDDLTQSS ETASEDCELP HSSYKNFMLL IEQLGMECKD 730 740 750 760 770 780 SVSLLKIQDA ALSCERLLEL KKNHCELLTV KIKKMEDKVN VLQRELSETK EIKSQLEHQK 790 800 810 820 830 840 VEWERELCSL RFSLNQEEEK RRNADTLYEK IREQLRRKEE QYRKEVEVKQ QLELSLQTLE 850 860 870 880 890 900 MELRTVKSNL NQVVQERNDA QRQLSREQNA RMLQDGILTN HLSKQKEIEM AQKKMNSENS 910 920 930 940 950 960 HSHEEEKDLS HKNSMLQEEI AMLRLEIDTI KNQNQEKEKK CFEDLKIVKE KNEDLQKTIK 970 980 990 1000 1010 1020 QNEETLTQTI SQYNGRLSVL TAENAMLNSK LENEKQSKER LEAEVESYHS RLAAAIHDRD 1030 1040 1050 1060 1070 1080 QSETSKRELE LAFQRARDEC SRLQDKMNFD VSNLKDNNEI LSQQLFKTES KLNSLEIEFH 1090 1100 1110 1120 1130 1140 HTRDALREKT LGLERVQKDL SQTQCQMKEM EQKYQNEQVK VNKYIGKQES VEERLSQLQS 1150 1160 1170 1180 1190 1200 ENMLLRQQLD DAHNKADNKE KTVINIQDQF HAIVQKLQAE SEKQSLLLEE RNKELISECN 1210 1220 1230 1240 1250 1260 HLKERQYQYE NEKAEREVVV RQLQQELADT LKKQSMSEAS LEVTSRYRIN LEDETQDLKK 1270 1280 1290 1300 1310 1320 KLGQIRNQLQ EAQDRHTEAV RCAEKMQDHK QKLEKDNAKL KVTVKKQMDK IEELQKNLLN 1330 1340 1350 1360 1370 1380 ANLSEDEKEQ LKKLMELKQS LECNLDQEMK KNVELEREIT GFKNLLKMTR KKLNEYENGE 1390 1400 1410 1420 1430 1440 FSFHGDLKTS QFEMDIQINK LKHKIDDLTA ELETAGSKCL HLDTKNQILQ EELLSMKTVQ 1450 1460 1470 1480 1490 1500 KKCEKLQKNK KKLEQEVINL RSHIERNMVE LGQVKQYKQE IEERARQEIA EKLKEVNLFL 1510 1520 1530 1540 1550 1560 QAQAASQENL EQFRENNFAS MKSQMELRIK DLESELSKIK TSQEDFNKTE LEKYKQLYLE 1570 1580 1590 1600 1610 1620 ELKVRKSLSS KLTKTNERLA EVNTKLLVEK QQSRSLFTTL TTRPVMEPPC VGNLNNSLDL 1630 1640 1650 1660 1670 1680 NRKLIPRENL VISTSNPRAS NNSMENYLSK MQQELEKNIT RELKEAAAEL ESGSIASPLG 1690 1700 STDESNLNQD LVWKASREYV QVLKKNYMI
	Isoform 2 [UniParc]. Checksum: 3F635BC067B3CBDE	FASTA	1,267	148,309
	10 20 30 40 50 60 MNHMFHIKRH SISAGTDAYK KTKPIQNLFQ KPLYDHCSAN NYKSMEPELE NVRSSPPRGD 70 80 90 100 110 120 RTSKVSLKEE LQQDMQRFKN EIGMLKVEFQ ALEKEKVQLQ KEVEEERKKH RNNEMEVSAN 130 140 150 160 170 180 IHDGATDDAE DDDDDDGLIQ KRKSGETDHQ QFPRKENKEY ASSGPALQMK EVKSTEKEKR 190 200 210 220 230 240 TSKESVNSPV FGKASLLTGG LLQVDDDSSL SEIDEDEGRP TKKTSNEKNK VKNQIQSMDD 250 260 270 280 290 300 VDDLTQSSET ASEDCELPHS SYKNFMLLIE QLGMECKDSV SLLKIQDAAL SCERLLELKK 310 320 330 340 350 360 NHCELLTVKI KKMEDKVNVL QRELSETKEI KSQLEHQKVE WERELCSLRF SLNQEEEKRR 370 380 390 400 410 420 NADTLYEKIR EQLRRKEEQY RKEVEVKQQL ELSLQTLEME LRTVKSNLNQ VVQERNDAQR 430 440 450 460 470 480 QLSREQNARM LQDGILTNHL SKQKEIEMAQ KKMNSENSHS HEEEKDLSHK NSMLQEEIAM 490 500 510 520 530 540 LRLEIDTIKN QNQEKEKKCF EDLKIVKEKN EDLQKTIKQN EETLTQTISQ YNGRLSVLTA 550 560 570 580 590 600 ENAMLNSKLE NEKQSKERLE AEVESYHSRL AAAIHDRDQS ETSKRELELA FQRARDECSR 610 620 630 640 650 660 LQDKMNFDVS NLKDNNEILS QQLFKTESKL NSLEIEFHHT RDALREKTLG LERVQKDLSQ 670 680 690 700 710 720 TQCQMKEMEQ KYQNEQVKVN KYIGKQESVE ERLSQLQSEN MLLRQQLDDA HNKADNKEKT 730 740 750 760 770 780 VINIQDQFHA IVQKLQAESE KQSLLLEERN KELISECNHL KERQYQYENE KAEREVVVRQ 790 800 810 820 830 840 LQQELADTLK KQSMSEASLE VTSRYRINLE DETQDLKKKL GQIRNQLQEA QDRHTEAVRC 850 860 870 880 890 900 AEKMQDHKQK LEKDNAKLKV TVKKQMDKIE ELQKNLLNAN LSEDEKEQLK KLMELKQSLE 910 920 930 940 950 960 CNLDQEMKKN VELEREITGF KNLLKMTRKK LNEYENGEFS FHGDLKTSQF EMDIQINKLK 970 980 990 1000 1010 1020 HKIDDLTAEL ETAGSKCLHL DTKNQILQEE LLSMKTVQKK CEKLQKNKKK LEQEVINLRS 1030 1040 1050 1060 1070 1080 HIERNMVELG QVKQYKQEIE ERARQEIAEK LKEVNLFLQA QAASQENLEQ FRENNFASMK 1090 1100 1110 1120 1130 1140 SQMELRIKDL ESELSKIKTS QEDFNKTELE KYKQLYLEEL KVRKSLSSKL TKTNERLAEV 1150 1160 1170 1180 1190 1200 NTKLLVEKQQ SRSLFTTLTT RPVMEPPCVG NLNNSLDLNR KLIPRENLVI STSNPRASNN 1210 1220 1230 1240 1250 1260 SMENYLSKMQ QELEKNITRE LKEAAAELES GSIASPLGST DESNLNQDLV WKASREYVQV LKKNYMI
	Isoform 3 [UniParc]. Checksum: 01CBF9BADB894872	FASTA	1,710	196,411
	10 20 30 40 50 60 MKKIFSKKGE SPLGSFARRQ RSSAGGGGEP GEGAYSQPGY HVRDRDLGKI HKAASAGNVA 70 80 90 100 110 120 KVQQILLLRK NGLNDRDKMN RTALHLACAN GHPEVVTLLV DRKCQLNVCD NENRTALMKA 130 140 150 160 170 180 VQCQEEKCAT ILLEHGADPN LADVHGNTAL HYAVYNEDIS VATKLLLYDA NIEAKNKDDL 190 200 210 220 230 240 TPLLLAVSGK KQQMVEFLIK KKANVNAVDK LESSHQLISE YKEERIPKHS SQNSNSVDES 250 260 270 280 290 300 SEDSLSRLSG KPGVDDSWPT SDDEDLNFDT KNVPKPSLAK LMTASQQSRK NLEATYGTVR 310 320 330 340 350 360 TGNRTLFEDR DSDSQDEVVV ESLPTTSIKV QCFSHPTYQS PDLLPKPSHK SLANPGLMKE 370 380 390 400 410 420 EPTKPGIAKK ENGIDIIESA PLEQTNNDNL TYVDEVHKNN RSDMMSALGL GQEEDIESPW 430 440 450 460 470 480 DSESISENFP QKYVDPLAGA ADGKEKNIGN EQAEDVFYIP SCMSGSRNFK MAKLEDTRNV 490 500 510 520 530 540 GMPVAHMESP ERYLHLKPTI EMKDSVPNKA GGMKDVQTSK AAEHDLEVAS EEEQEREGSE 550 560 570 580 590 600 NNQPQVEEER KKHRNNEMEV SANIHDGATD DAEDDDDDDG LIQKRKSGET DHQQFPRKEN 610 620 630 640 650 660 KEYASSGPAL QMKEVKSTEK EKRTSKESVN SPVFGKASLL TGGLLQVDDD SSLSEIDEDE 670 680 690 700 710 720 GRPTKKTSNE KNKVKNQIQS MDDVDDLTQS SETASEDCEL PHSSYKNFML LIEQLGMECK 730 740 750 760 770 780 DSVSLLKIQD AALSCERLLE LKKNHCELLT VKIKKMEDKV NVLQRELSET KEIKSQLEHQ 790 800 810 820 830 840 KVEWERELCS LRFSLNQEEE KRRNADTLYE KIREQLRRKE EQYRKEVEVK QQLELSLQTL 850 860 870 880 890 900 EMELRTVKSN LNQVVQERND AQRQLSREQN ARMLQDGILT NHLSKQKEIE MAQKKMNSEN 910 920 930 940 950 960 SHSHEEEKDL SHKNSMLQEE IAMLRLEIDT IKNQNQEKEK KCFEDLKIVK EKNEDLQKTI 970 980 990 1000 1010 1020 KQNEETLTQT ISQYNGRLSV LTAENAMLNS KLENEKQSKE RLEAEVESYH SRLAAAIHDR 1030 1040 1050 1060 1070 1080 DQSETSKREL ELAFQRARDE CSRLQDKMNF DVSNLKDNNE ILSQQLFKTE SKLNSLEIEF 1090 1100 1110 1120 1130 1140 HHTRDALREK TLGLERVQKD LSQTQCQMKE MEQKYQNEQV KVNKYIGKQE SVEERLSQLQ 1150 1160 1170 1180 1190 1200 SENMLLRQQL DDAHNKADNK EKTVINIQDQ FHAIVQKLQA ESEKQSLLLE ERNKELISEC 1210 1220 1230 1240 1250 1260 NHLKERQYQY ENEKAEREVV VRQLQQELAD TLKKQSMSEA SLEVTSRYRI NLEDETQDLK 1270 1280 1290 1300 1310 1320 KKLGQIRNQL QEAQDRHTEA VRCAEKMQDH KQKLEKDNAK LKVTVKKQMD KIEELQKNLL 1330 1340 1350 1360 1370 1380 NANLSEDEKE QLKKLMELKQ SLECNLDQEM KKNVELEREI TGFKNLLKMT RKKLNEYENG 1390 1400 1410 1420 1430 1440 EFSFHGDLKT SQFEMDIQIN KLKHKIDDLT AELETAGSKC LHLDTKNQIL QEELLSMKTV 1450 1460 1470 1480 1490 1500 QKKCEKLQKN KKKLEQEVIN LRSHIERNMV ELGQVKQYKQ EIEERARQEI AEKLKEVNLF 1510 1520 1530 1540 1550 1560 LQAQAASQEN LEQFRENNFA SMKSQMELRI KDLESELSKI KTSQEDFNKT ELEKYKQLYL 1570 1580 1590 1600 1610 1620 EELKVRKSLS SKLTKTNERL AEVNTKLLVE KQQSRSLFTT LTTRPVMEPP CVGNLNNSLD 1630 1640 1650 1660 1670 1680 LNRKLIPREN LVISTSNPRA SNNSMENYLS KMQQELEKNI TRELKEAAAE LESGSIASPL 1690 1700 1710 GSTDESNLNQ DLVWKASREY VQVLKKNYMI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." Kikuno R., Nagase T., Ishikawa K., Hirosawa M., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O. DNA Res. 6:197-205(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT ARG-20. Tissue: Brain.
[2]	"The DNA sequence and comparative analysis of human chromosome 10." Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J. , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J. Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-1522 (ISOFORM 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-546 (ISOFORM 1), VARIANTS ARG-20; ILE-1304 AND LEU-1513. Tissue: Embryo and Trachea.
[4]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1337-1709. Tissue: Melanoma and Testis.
[5]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1545-1709. Tissue: Lymph.
[6]	"Duplication and extensive remodeling shaped POTE family genes encoding proteins containing ankyrin repeat and coiled coil domains." Hahn Y., Bera T.K., Pastan I.H., Lee B. Gene 366:238-245(2006) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION.
[7]	"ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III, Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N., Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J. Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. Tissue: Embryonic kidney.
[8]	"A quantitative atlas of mitotic phosphorylation." Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. Tissue: Cervix carcinoma.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB028997 mRNA. Translation: BAA83026.2. Different initiation. AL162272 Genomic DNA. Translation: CAC19649.1. AK001137 mRNA. Translation: BAA91516.1. AK128577 mRNA. Translation: BAC87508.1. AL137351 mRNA. Translation: CAB70706.1. AL162063 mRNA. Translation: CAB82401.1. BC110646 mRNA. Translation: AAI10647.1.
IPI	IPI00007193. IPI00760833. IPI00793360.
PIR	T46425. T47167.
RefSeq	NP_001242982.1. NM_001256053.1. NP_055730.2. NM_014915.2.
UniGene	Hs.361041.
3D structure databases
ProteinModelPortal	Q9UPS8.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9UPS8. 2 interactions.
STRING	9606.ENSP00000365255.
PTM databases
PhosphoSite	Q9UPS8.
Polymorphism databases
DMDM	109940217.
Proteomic databases
PaxDb	Q9UPS8.
PRIDE	Q9UPS8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000376070; ENSP00000365238; ENSG00000107890. ENST00000376087; ENSP00000365255; ENSG00000107890.
GeneID	22852.
KEGG	hsa:22852.
UCSC	uc001ith.2. human. uc009xku.1. human.
Organism-specific databases
CTD	22852.
GeneCards	GC10M027280.
H-InvDB	HIX0008724. HIX0010691. HIX0026961. HIX0037339.
HGNC	HGNC:29186. ANKRD26.
HPA	HPA040654. HPA041460.
MIM	610855. gene.
neXtProt	NX_Q9UPS8.
Orphanet	168629. Autosomal thrombocytopenia with normal platelets.
PharmGKB	PA134926710.
HUGE	Search...
GenAtlas	Search...
Phylogenomic databases
eggNOG	COG0666.
HOVERGEN	HBG079895.
InParanoid	Q9UPS8.
Gene expression databases
ArrayExpress	Q9UPS8.
Bgee	Q9UPS8.
CleanEx	HS_ANKRD26.
Genevestigator	Q9UPS8.
GermOnline	ENSG00000107890. Homo sapiens.
Family and domain databases
Gene3D	1.25.40.20. 1 hit.
InterPro	IPR002110. Ankyrin_rpt. IPR020683. Ankyrin_rpt-contain_dom. IPR021885. DUF3496. [Graphical view]
Pfam	PF00023. Ank. 2 hits. PF12796. Ank_2. 1 hit. PF12001. DUF3496. 1 hit. [Graphical view]
PRINTS	PR01415. ANKYRIN.
SMART	SM00248. ANK. 4 hits. [Graphical view]
SUPFAM	SSF48403. ANK. 1 hit.
PROSITE	PS50297. ANK_REP_REGION. 1 hit. PS50088. ANK_REPEAT. 4 hits. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	22852.
NextBio	43329.
SOURCE	Search...

Entry information

Entry name

ANR26_HUMAN

Accession

Primary (citable) accession number: Q9UPS8
Secondary accession number(s): A6NH29 , Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	June 27, 2006
Last modified:	May 1, 2013
This is version 94 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.