Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

LIM and calponin homology domains-containing protein 1

Gene

LIMCH1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciZFISH:ENSG00000064042-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
LIM and calponin homology domains-containing protein 1
Gene namesi
Name:LIMCH1
Synonyms:KIAA1102
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

HGNCiHGNC:29191. LIMCH1.

Pathology & Biotechi

Organism-specific databases

DisGeNETi22998.
OpenTargetsiENSG00000064042.
PharmGKBiPA162393957.

Polymorphism and mutation databases

BioMutaiLIMCH1.
DMDMi296439483.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002936191 – 1083LIM and calponin homology domains-containing protein 1Add BLAST1083

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei169PhosphoserineCombined sources1
Modified residuei177PhosphoserineBy similarity1
Modified residuei192PhosphoserineCombined sources1
Modified residuei201PhosphoserineCombined sources1
Modified residuei204PhosphoserineCombined sources1
Modified residuei207PhosphoserineCombined sources1
Modified residuei215PhosphothreonineCombined sources1
Modified residuei217PhosphoserineCombined sources1
Modified residuei226PhosphoserineBy similarity1
Modified residuei231PhosphoserineCombined sources1
Modified residuei233PhosphoserineCombined sources1
Modified residuei297PhosphoserineCombined sources1
Modified residuei303PhosphoserineCombined sources1
Modified residuei313PhosphotyrosineBy similarity1
Modified residuei377PhosphoserineCombined sources1
Modified residuei402PhosphothreonineCombined sources1
Modified residuei471PhosphoserineCombined sources1
Modified residuei472PhosphothreonineBy similarity1
Modified residuei516PhosphoserineCombined sources1
Modified residuei518PhosphoserineCombined sources1
Modified residuei523PhosphoserineCombined sources1
Modified residuei529PhosphothreonineCombined sources1
Modified residuei537PhosphothreonineCombined sources1
Modified residuei601PhosphoserineCombined sources1
Modified residuei670PhosphoserineCombined sources1
Modified residuei681PhosphoserineCombined sources1
Modified residuei718PhosphoserineCombined sources1
Modified residuei724PhosphothreonineCombined sources1
Modified residuei750PhosphoserineBy similarity1
Modified residuei756PhosphoserineBy similarity1
Modified residuei875PhosphoserineCombined sources1
Modified residuei900PhosphothreonineBy similarity1
Modified residuei966PhosphoserineCombined sources1
Modified residuei973PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ9UPQ0.
PaxDbiQ9UPQ0.
PeptideAtlasiQ9UPQ0.
PRIDEiQ9UPQ0.

PTM databases

iPTMnetiQ9UPQ0.
PhosphoSitePlusiQ9UPQ0.

Expressioni

Gene expression databases

BgeeiENSG00000064042.
CleanExiHS_LIMCH1.
ExpressionAtlasiQ9UPQ0. baseline and differential.
GenevisibleiQ9UPQ0. HS.

Organism-specific databases

HPAiHPA004184.
HPA063840.

Interactioni

Protein-protein interaction databases

BioGridi116645. 39 interactors.
IntActiQ9UPQ0. 21 interactors.
MINTiMINT-4724874.
STRINGi9606.ENSP00000316891.

Structurei

3D structure databases

ProteinModelPortaliQ9UPQ0.
SMRiQ9UPQ0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini21 – 125CHPROSITE-ProRule annotationAdd BLAST105
Domaini1011 – 1077LIM zinc-bindingPROSITE-ProRule annotationAdd BLAST67

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili348 – 439Sequence analysisAdd BLAST92

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi771 – 826Glu-richAdd BLAST56

Sequence similaritiesi

Belongs to the LIMCH1 family.Curated
Contains 1 CH (calponin-homology) domain.PROSITE-ProRule annotation
Contains 1 LIM zinc-binding domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil, LIM domain

Phylogenomic databases

eggNOGiENOG410INGA. Eukaryota.
ENOG410XQB9. LUCA.
GeneTreeiENSGT00530000063559.
HOVERGENiHBG108087.
InParanoidiQ9UPQ0.
PhylomeDBiQ9UPQ0.
TreeFamiTF332155.

Family and domain databases

CDDicd00014. CH. 1 hit.
Gene3Di1.10.418.10. 1 hit.
2.10.110.10. 1 hit.
InterProiIPR001997. Calponin/LIMCH1.
IPR001715. CH-domain.
IPR031865. DUF4757.
IPR029980. LIMCH1.
IPR003096. SM22_calponin.
IPR001781. Znf_LIM.
[Graphical view]
PANTHERiPTHR15551:SF3. PTHR15551:SF3. 1 hit.
PfamiPF00307. CH. 1 hit.
PF15949. DUF4757. 1 hit.
PF00412. LIM. 1 hit.
[Graphical view]
PRINTSiPR00889. CALPONIN.
PR00888. SM22CALPONIN.
SMARTiSM00033. CH. 1 hit.
SM00132. LIM. 1 hit.
[Graphical view]
SUPFAMiSSF47576. SSF47576. 1 hit.
PROSITEiPS50021. CH. 1 hit.
PS00478. LIM_DOMAIN_1. 1 hit.
PS50023. LIM_DOMAIN_2. 1 hit.
[Graphical view]

Sequences (10)i

Sequence statusi: Complete.

This entry describes 10 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q9UPQ0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MACPALGLEA LQPLQPEPPP EPAFSEAQKW IEQVTGRSFG DKDFRTGLEN
60 70 80 90 100
GILLCELLNA IKPGLVKKIN RLPTPIAGLD NIILFLRGCK ELGLKESQLF
110 120 130 140 150
DPSDLQDTSN RVTVKSLDYS RKLKNVLVTI YWLGKAANSC TSYSGTTLNL
160 170 180 190 200
KEFEGLLAQM RKDTDDIESP KRSIRDSGYI DCWDSERSDS LSPPRHGRDD
210 220 230 240 250
SFDSLDSFGS RSRQTPSPDV VLRGSSDGRG SDSESDLPHR KLPDVKKDDM
260 270 280 290 300
SARRTSHGEP KSAVPFNQYL PNKSNQTAYV PAPLRKKKAE REEYRKSWST
310 320 330 340 350
ATSPLGGERP FRYGPRTPVS DDAESTSMFD MRCEEEAAVQ PHSRARQEQL
360 370 380 390 400
QLINNQLREE DDKWQDDLAR WKSRRRSVSQ DLIKKEEERK KMEKLLAGED
410 420 430 440 450
GTSERRKSIK TYREIVQEKE RRERELHEAY KNARSQEEAE GILQQYIERF
460 470 480 490 500
TISEAVLERL EMPKILERSH STEPNLSSFL NDPNPMKYLR QQSLPPPKFT
510 520 530 540 550
ATVETTIARA SVLDTSMSAG SGSPSKTVTP KAVPMLTPKP YSQPKNSQDV
560 570 580 590 600
LKTFKVDGKV SVNGETVHRE EEKERECPTV APAHSLTKSQ MFEGVARVHG
610 620 630 640 650
SPLELKQDNG SIEINIKKPN SVPQELAATT EKTEPNSQED KNDGGKSRKG
660 670 680 690 700
NIELASSEPQ HFTTTVTRCS PTVAFVEFPS SPQLKNDVSE EKDQKKPENE
710 720 730 740 750
MSGKVELVLS QKVVKPKSPE PEATLTFPFL DKMPEANQLH LPNLNSQVDS
760 770 780 790 800
PSSEKSPVMT PQFKFWAWDP EEERRRQEKW QQEQERLLQE RYQKEQDKLK
810 820 830 840 850
EEWEKAQKEV EEEERRYYEE ERKIIEDTVV PFTVSSSSAD QLSTSSSMTE
860 870 880 890 900
GSGTMNKIDL GNCQDEKQDR RWKKSFQGDD SDLLLKTRES DRLEEKGSLT
910 920 930 940 950
EGALAHSGNP VSKGVHEDHQ LDTEAGAPHC GTNPQLAQDP SQNQQTSNPT
960 970 980 990 1000
HSSEDVKPKT LPLDKSINHQ IESPSERRKK SPREHFQAGP FSPCSPTPPG
1010 1020 1030 1040 1050
QSPNRSISGK KLCSSCGLPL GKGAAMIIET LNLYFHIQCF RCGICKGQLG
1060 1070 1080
DAVSGTDVRI RNGLLNCNDC YMRSRSAGQP TTL
Length:1,083
Mass (Da):121,867
Last modified:May 18, 2010 - v4
Checksum:i19C8BA192EDBDC6B
GO
Isoform 2 (identifier: Q9UPQ0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     980-1005: Missing.

Show »
Length:1,057
Mass (Da):119,078
Checksum:i0941CE1DC5A787A8
GO
Isoform 3 (identifier: Q9UPQ0-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-159: Missing.
     311-311: F → FSFPETIEEE...SSKGLPMKDQ
     762-762: Missing.

Note: No experimental confirmation available.
Show »
Length:1,467
Mass (Da):164,440
Checksum:i0D87F5D5CC068B60
GO
Isoform 4 (identifier: Q9UPQ0-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     313-324: Missing.
     747-747: Q → QESPGTASVPLRVQNSWRRSQFFSQS
     762-762: Missing.
     980-1005: Missing.

Note: No experimental confirmation available.
Show »
Length:1,069
Mass (Da):120,496
Checksum:iDFE247E4E66028D9
GO
Isoform 5 (identifier: Q9UPQ0-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-159: Missing.
     313-324: Missing.
     747-747: Q → QESPGTASVPLRVQNSWRRSQFFSQS
     762-762: Missing.
     980-1005: Missing.

Note: No experimental confirmation available.
Show »
Length:910
Mass (Da):103,010
Checksum:i569E37A38F29AB9A
GO
Isoform 6 (identifier: Q9UPQ0-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-154: Missing.
     155-161: GLLAQMR → MDSERQV
     762-762: Missing.
     980-1005: Missing.

Show »
Length:902
Mass (Da):102,022
Checksum:i7584455BA8EAEC5D
GO
Isoform 7 (identifier: Q9UPQ0-7) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-159: Missing.
     288-297: KAEREEYRKS → NADTMRRSVR
     298-1083: Missing.

Note: No experimental confirmation available.
Show »
Length:138
Mass (Da):15,551
Checksum:i7829A68BD11C1097
GO
Isoform 8 (identifier: Q9UPQ0-8) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-159: Missing.
     762-762: Missing.
     980-1005: Missing.

Show »
Length:897
Mass (Da):101,464
Checksum:iE6A5FF8C3D53D2F9
GO
Isoform 9 (identifier: Q9UPQ0-9) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-154: Missing.
     155-161: GLLAQMR → MDSERQV
     313-324: Missing.
     762-762: Missing.
     980-1005: Missing.

Show »
Length:890
Mass (Da):100,734
Checksum:iD0F8D08238E15CDD
GO
Isoform 10 (identifier: Q9UPQ0-10) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     762-762: Missing.
     980-1005: Missing.

Note: No experimental confirmation available.
Show »
Length:1,056
Mass (Da):118,950
Checksum:i69BBB44235180481
GO

Sequence cautioni

The sequence BAA83054 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti17E → G in CAI56749 (PubMed:17974005).Curated1
Sequence conflicti142S → P in CR936664 (PubMed:17974005).Curated1
Sequence conflicti207S → F in CAI56749 (PubMed:17974005).Curated1
Sequence conflicti409I → T in CR936664 (PubMed:17974005).Curated1
Sequence conflicti537T → I in CAH18063 (PubMed:17974005).Curated1
Sequence conflicti611S → G in CAD38604 (PubMed:17974005).Curated1
Sequence conflicti622V → I in CR936664 (PubMed:17974005).Curated1
Sequence conflicti706E → G in CAI56754 (PubMed:17974005).Curated1
Sequence conflicti750S → P in CAD38604 (PubMed:17974005).Curated1
Sequence conflicti867K → N in CAH18063 (PubMed:17974005).Curated1
Sequence conflicti1053V → A in CAD38604 (PubMed:17974005).Curated1
Sequence conflicti1059R → G in CAI45946 (PubMed:17974005).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_033105759M → T.3 PublicationsCorresponds to variant rs11734372dbSNPEnsembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0265411 – 159Missing in isoform 3, isoform 5, isoform 7 and isoform 8. 2 PublicationsAdd BLAST159
Alternative sequenceiVSP_0265421 – 154Missing in isoform 6 and isoform 9. 1 PublicationAdd BLAST154
Alternative sequenceiVSP_026543155 – 161GLLAQMR → MDSERQV in isoform 6 and isoform 9. 1 Publication7
Alternative sequenceiVSP_026544288 – 297KAEREEYRKS → NADTMRRSVR in isoform 7. 1 Publication10
Alternative sequenceiVSP_026545298 – 1083Missing in isoform 7. 1 PublicationAdd BLAST786
Alternative sequenceiVSP_026546311F → FSFPETIEEEGSEVGSAGED NPAGQMNPGWKPSDGGCELP DGSGKEHPSSDGAVVAPAPK SEEKDAAEIQKRERLEQAGI KVMPAAQRFASQKQLSEEKE AIRDIVLRKENSFLTHQHGN DSEAEGEVVCRLPDLEKDDF AARRARMNQTKPMVPLNQLL YGPYPKKGAEKSDGSKQLSK GISKKRSLEYKRNQGHTEEV KLIVTCNMRAQESEPVEGGL RKVPDLHKDDLAQQRIQGSL APHREPPSFITLSNITEADL ETWERLKVSEKARDGDVQHI CASEPSPEIKAETAIRDDFA NRKARASKKASSPRQKFVHF GPVTELDQQKWKRLSIGKAG PREDEEEVICHGSKIQMDSV SPVSAATSSLKGHQIFNRQN DCRTMNCGRGDYCRRASWLA PVPESQEEWVCSLGECPRGT EEVTSKQLPQDGKEETESAP RDSERLSKAERSEDSSQPLV CPLASECEASGTEEKLEKMT APAWSGSGLKGQRKLDDSRK DDMMARRTGMSLRHTGSNPN QFLPVPFAKQQDVEESSKGL PMKDQ in isoform 3. 1 Publication1
Alternative sequenceiVSP_026547313 – 324Missing in isoform 4, isoform 5 and isoform 9. 1 PublicationAdd BLAST12
Alternative sequenceiVSP_026548747Q → QESPGTASVPLRVQNSWRRS QFFSQS in isoform 4 and isoform 5. 1 Publication1
Alternative sequenceiVSP_026549762Missing in isoform 3, isoform 4, isoform 5, isoform 6, isoform 8, isoform 9 and isoform 10. 2 Publications1
Alternative sequenceiVSP_026550980 – 1005Missing in isoform 2, isoform 4, isoform 5, isoform 6, isoform 8, isoform 9 and isoform 10. 2 PublicationsAdd BLAST26

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB029025 mRNA. Translation: BAA83054.2. Different initiation.
AL831962 mRNA. Translation: CAD38604.1.
BX537916 mRNA. Translation: CAD97899.1.
CR749205 mRNA. Translation: CAH18063.1.
CR933645 mRNA. Translation: CAI45946.1.
CR936601 mRNA. Translation: CAI56749.1.
CR936610 mRNA. Translation: CAI56754.1.
CR936664 mRNA. No translation available.
AC095043 Genomic DNA. No translation available.
AC105389 Genomic DNA. No translation available.
AC108050 Genomic DNA. No translation available.
AC121159 Genomic DNA. No translation available.
AC124009 Genomic DNA. No translation available.
BC023546 mRNA. Translation: AAH23546.1.
BC029735 mRNA. Translation: AAH29735.1.
BC095394 mRNA. Translation: AAH95394.1.
CCDSiCCDS33977.1. [Q9UPQ0-1]
CCDS47047.1. [Q9UPQ0-6]
CCDS54763.1. [Q9UPQ0-2]
CCDS54764.1. [Q9UPQ0-10]
CCDS54765.1. [Q9UPQ0-9]
CCDS75119.1. [Q9UPQ0-4]
CCDS75121.1. [Q9UPQ0-5]
CCDS82919.1. [Q9UPQ0-3]
RefSeqiNP_001106188.1. NM_001112717.3. [Q9UPQ0-2]
NP_001106189.1. NM_001112718.3. [Q9UPQ0-10]
NP_001106190.1. NM_001112719.3. [Q9UPQ0-6]
NP_001106191.1. NM_001112720.3. [Q9UPQ0-9]
NP_001276051.1. NM_001289122.2. [Q9UPQ0-4]
NP_001276053.1. NM_001289124.1. [Q9UPQ0-5]
NP_001317601.1. NM_001330672.1.
NP_001317603.1. NM_001330674.1.
NP_001317713.1. NM_001330784.1.
NP_001317715.1. NM_001330786.1.
NP_055803.2. NM_014988.4. [Q9UPQ0-1]
UniGeneiHs.335163.

Genome annotation databases

EnsembliENST00000313860; ENSP00000316891; ENSG00000064042. [Q9UPQ0-1]
ENST00000381753; ENSP00000371172; ENSG00000064042. [Q9UPQ0-9]
ENST00000396595; ENSP00000379840; ENSG00000064042. [Q9UPQ0-6]
ENST00000508501; ENSP00000424825; ENSG00000064042. [Q9UPQ0-10]
ENST00000511496; ENSP00000421242; ENSG00000064042. [Q9UPQ0-8]
ENST00000512820; ENSP00000424437; ENSG00000064042. [Q9UPQ0-4]
ENST00000512946; ENSP00000424645; ENSG00000064042. [Q9UPQ0-2]
ENST00000513024; ENSP00000425222; ENSG00000064042. [Q9UPQ0-5]
GeneIDi22998.
KEGGihsa:22998.
UCSCiuc003gvu.6. human. [Q9UPQ0-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB029025 mRNA. Translation: BAA83054.2. Different initiation.
AL831962 mRNA. Translation: CAD38604.1.
BX537916 mRNA. Translation: CAD97899.1.
CR749205 mRNA. Translation: CAH18063.1.
CR933645 mRNA. Translation: CAI45946.1.
CR936601 mRNA. Translation: CAI56749.1.
CR936610 mRNA. Translation: CAI56754.1.
CR936664 mRNA. No translation available.
AC095043 Genomic DNA. No translation available.
AC105389 Genomic DNA. No translation available.
AC108050 Genomic DNA. No translation available.
AC121159 Genomic DNA. No translation available.
AC124009 Genomic DNA. No translation available.
BC023546 mRNA. Translation: AAH23546.1.
BC029735 mRNA. Translation: AAH29735.1.
BC095394 mRNA. Translation: AAH95394.1.
CCDSiCCDS33977.1. [Q9UPQ0-1]
CCDS47047.1. [Q9UPQ0-6]
CCDS54763.1. [Q9UPQ0-2]
CCDS54764.1. [Q9UPQ0-10]
CCDS54765.1. [Q9UPQ0-9]
CCDS75119.1. [Q9UPQ0-4]
CCDS75121.1. [Q9UPQ0-5]
CCDS82919.1. [Q9UPQ0-3]
RefSeqiNP_001106188.1. NM_001112717.3. [Q9UPQ0-2]
NP_001106189.1. NM_001112718.3. [Q9UPQ0-10]
NP_001106190.1. NM_001112719.3. [Q9UPQ0-6]
NP_001106191.1. NM_001112720.3. [Q9UPQ0-9]
NP_001276051.1. NM_001289122.2. [Q9UPQ0-4]
NP_001276053.1. NM_001289124.1. [Q9UPQ0-5]
NP_001317601.1. NM_001330672.1.
NP_001317603.1. NM_001330674.1.
NP_001317713.1. NM_001330784.1.
NP_001317715.1. NM_001330786.1.
NP_055803.2. NM_014988.4. [Q9UPQ0-1]
UniGeneiHs.335163.

3D structure databases

ProteinModelPortaliQ9UPQ0.
SMRiQ9UPQ0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi116645. 39 interactors.
IntActiQ9UPQ0. 21 interactors.
MINTiMINT-4724874.
STRINGi9606.ENSP00000316891.

PTM databases

iPTMnetiQ9UPQ0.
PhosphoSitePlusiQ9UPQ0.

Polymorphism and mutation databases

BioMutaiLIMCH1.
DMDMi296439483.

Proteomic databases

EPDiQ9UPQ0.
PaxDbiQ9UPQ0.
PeptideAtlasiQ9UPQ0.
PRIDEiQ9UPQ0.

Protocols and materials databases

DNASUi22998.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000313860; ENSP00000316891; ENSG00000064042. [Q9UPQ0-1]
ENST00000381753; ENSP00000371172; ENSG00000064042. [Q9UPQ0-9]
ENST00000396595; ENSP00000379840; ENSG00000064042. [Q9UPQ0-6]
ENST00000508501; ENSP00000424825; ENSG00000064042. [Q9UPQ0-10]
ENST00000511496; ENSP00000421242; ENSG00000064042. [Q9UPQ0-8]
ENST00000512820; ENSP00000424437; ENSG00000064042. [Q9UPQ0-4]
ENST00000512946; ENSP00000424645; ENSG00000064042. [Q9UPQ0-2]
ENST00000513024; ENSP00000425222; ENSG00000064042. [Q9UPQ0-5]
GeneIDi22998.
KEGGihsa:22998.
UCSCiuc003gvu.6. human. [Q9UPQ0-1]

Organism-specific databases

CTDi22998.
DisGeNETi22998.
GeneCardsiLIMCH1.
H-InvDBHIX0004177.
HIX0120158.
HGNCiHGNC:29191. LIMCH1.
HPAiHPA004184.
HPA063840.
neXtProtiNX_Q9UPQ0.
OpenTargetsiENSG00000064042.
PharmGKBiPA162393957.
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410INGA. Eukaryota.
ENOG410XQB9. LUCA.
GeneTreeiENSGT00530000063559.
HOVERGENiHBG108087.
InParanoidiQ9UPQ0.
PhylomeDBiQ9UPQ0.
TreeFamiTF332155.

Enzyme and pathway databases

BioCyciZFISH:ENSG00000064042-MONOMER.

Miscellaneous databases

ChiTaRSiLIMCH1. human.
GeneWikiiLIMCH1.
GenomeRNAii22998.
PROiQ9UPQ0.

Gene expression databases

BgeeiENSG00000064042.
CleanExiHS_LIMCH1.
ExpressionAtlasiQ9UPQ0. baseline and differential.
GenevisibleiQ9UPQ0. HS.

Family and domain databases

CDDicd00014. CH. 1 hit.
Gene3Di1.10.418.10. 1 hit.
2.10.110.10. 1 hit.
InterProiIPR001997. Calponin/LIMCH1.
IPR001715. CH-domain.
IPR031865. DUF4757.
IPR029980. LIMCH1.
IPR003096. SM22_calponin.
IPR001781. Znf_LIM.
[Graphical view]
PANTHERiPTHR15551:SF3. PTHR15551:SF3. 1 hit.
PfamiPF00307. CH. 1 hit.
PF15949. DUF4757. 1 hit.
PF00412. LIM. 1 hit.
[Graphical view]
PRINTSiPR00889. CALPONIN.
PR00888. SM22CALPONIN.
SMARTiSM00033. CH. 1 hit.
SM00132. LIM. 1 hit.
[Graphical view]
SUPFAMiSSF47576. SSF47576. 1 hit.
PROSITEiPS50021. CH. 1 hit.
PS00478. LIM_DOMAIN_1. 1 hit.
PS50023. LIM_DOMAIN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiLIMC1_HUMAN
AccessioniPrimary (citable) accession number: Q9UPQ0
Secondary accession number(s): A8MXC3
, E9PHM7, Q503B5, Q5CZB1, Q5CZB6, Q5H9S8, Q68E07, Q6PJ44, Q7Z3G5, Q8N3S9, Q8N6M2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: May 18, 2010
Last modified: November 30, 2016
This is version 119 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.