UniProtKB - Q9UPP5 (K1107_HUMAN)
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Protein
Uncharacterized protein KIAA1107
Gene
KIAA1107
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Uncharacterized protein KIAA1107 |
Gene namesi | Name:KIAA1107 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:29192. KIAA1107. |
neXtProti | NX_Q9UPP5. |
Pathology & Biotechi
Organism-specific databases
PharmGKBi | PA142671620. |
Polymorphism and mutation databases
BioMutai | KIAA1107. |
DMDMi | 172045554. |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000320677 | 1 – 1409 | Uncharacterized protein KIAA1107Add BLAST | 1409 |
Proteomic databases
PaxDbi | Q9UPP5. |
PeptideAtlasi | Q9UPP5. |
PRIDEi | Q9UPP5. |
PTM databases
iPTMneti | Q9UPP5. |
PhosphoSitePlusi | Q9UPP5. |
Expressioni
Gene expression databases
CleanExi | HS_KIAA1107. |
Organism-specific databases
HPAi | HPA024216. HPA027327. |
Interactioni
Protein-protein interaction databases
BioGridi | 116883. 22 interactors. |
IntActi | Q9UPP5. 23 interactors. |
MINTi | Q9UPP5. |
Family & Domainsi
Phylogenomic databases
eggNOGi | ENOG410IFU8. Eukaryota. ENOG4111MST. LUCA. |
HOGENOMi | HOG000168280. |
HOVERGENi | HBG108026. |
InParanoidi | Q9UPP5. |
PhylomeDBi | Q9UPP5. |
Family and domain databases
InterProi | View protein in InterPro IPR027907. DUF4596. |
Pfami | View protein in Pfam PF15363. DUF4596. 1 hit. |
s (2)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q9UPP5-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
10 20 30 40 50
MESDRLIISL PRVKWTEAAL TMASQLQEKC IAFIVDNFSK IIQSENFALL
60 70 80 90 100
LQSQAMSSTA DLLDTILKAI EENITTENSC SLLMALDTLL NSDSTKEMGF
110 120 130 140 150
TCKIQALRDK LWIFLVQSFY AVRHTESWKL MSTDDQQKIQ AAAFDKGDDR
160 170 180 190 200
RLGKKPIFSS SQQRKQVSDS GDIKIKSWRG NNKKECWSYL STNKKMKSDG
210 220 230 240 250
LGASGHSSST NRNSINKTLK QDDVKEKDGT KIASKITKEL KTGGKNVSGK
260 270 280 290 300
PKTVTKSKTE NGDKARLENM SPRQVVERSA TAAAAATGQK NLLNGKGVRN
310 320 330 340 350
QEGQISGARP KVLTGNLNVQ AKAKPLKKAT GKDSPCLSIA GPSSRSTDSS
360 370 380 390 400
MEFSISTECL DEPKENGSTE EEKPSGHKLS FCDSPGQMMK NSVDSVKNST
410 420 430 440 450
VAIKSRPVSR VTNGTSNKKS IHEQDTNVNN SVLKKVSGKG CSEPVPQAIL
460 470 480 490 500
KKRGTSNGCT AAQQRTKSTP SNLTKTQGSQ GESPNSVKSS VSSRQSDENV
510 520 530 540 550
AKLDHNTTTE KQAPKRKMVK QVHTALPKVN AKIVAMPKNL NQSKKGETLN
560 570 580 590 600
NKDSKQKMPP GQVISKTQPS SQRPLKHETS TVQKSMFHDV RDNNNKDSVS
610 620 630 640 650
EQKPHKPLIN LASEISDAEA LQSSCRPDPQ KPLNDQEKEK LALECQNISK
660 670 680 690 700
LDKSLKHELE SKQICLDKSE TKFPNHKETD DCDAANICCH SVGSDNVNSK
710 720 730 740 750
FYSTTALKYM VSNPNENSLN SNPVCDLDST SAGQIHLISD RENQVGRKDT
760 770 780 790 800
NKQSSIKCVE DVSLCNPERT NGTLNSAQED KKSKVPVEGL TIPSKLSDES
810 820 830 840 850
AMDEDKHATA DSDVSSKCFS GQLSEKNSPK NMETSESPES HETPETPFVG
860 870 880 890 900
HWNLSTGVLH QRESPESDTG SATTSSDDIK PRSEDYDAGG SQDDDGSNDR
910 920 930 940 950
GISKCGTMLC HDFLGRSSSD TSTPEELKIY DSNLRIEVKM KKQSNNDLFQ
960 970 980 990 1000
VNSTSDDEIP RKRPEIWSRS AIVHSREREN IPRGSVQFAQ EIDQVSSSAD
1010 1020 1030 1040 1050
ETEDERSEAE NVAENFSISN PAPQQFQGII NLAFEDATEN ECREFSANKK
1060 1070 1080 1090 1100
FKRSVLLSVD ECEELGSDEG EVHTPFQASV DSFSPSDVFD GISHEHHGRT
1110 1120 1130 1140 1150
CYSRFSRESE DNILECKQNK GNSVCKNEST VLDLSSIDSS RKNKQSVSAT
1160 1170 1180 1190 1200
EKKNTIDVLS SRSRQLLRED KKVNNGSNVE NDIQQRSKFL DSDVKSQERP
1210 1220 1230 1240 1250
CHLDLHQREP NSDIPKNSST KSLDSFRSQV LPQEGPVKES HSTTTEKANI
1260 1270 1280 1290 1300
ALSAGDIDDC DTLAQTRMYD HRPSKTLSPI YEMDVIEAFE QKVESETHVT
1310 1320 1330 1340 1350
DMDFEDDQHF AKQDWTLLKQ LLSEQDSNLD VTNSVPEDLS LAQYLINQTL
1360 1370 1380 1390 1400
LLARDSSKPQ GITHIDTLNR WSELTSPLDS SASITMASFS SEDCSPQGEW
TILELETQH
Sequence cautioni
The sequence AAC28132 differs from that shown. Reason: Erroneous initiation.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 1016 | F → L in AAH37317 (PubMed:15489334).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_060300 | 422 | H → R. Corresponds to variant dbSNP:rs2128647Ensembl. | 1 | |
Natural variantiVAR_060301 | 442 | S → I. Corresponds to variant dbSNP:rs12084085Ensembl. | 1 | |
Natural variantiVAR_060302 | 522 | V → L. Corresponds to variant dbSNP:rs7552286Ensembl. | 1 | |
Natural variantiVAR_060303 | 602 | Q → R. Corresponds to variant dbSNP:rs11166332Ensembl. | 1 | |
Natural variantiVAR_060304 | 681 | D → G. Corresponds to variant dbSNP:rs7523466Ensembl. | 1 | |
Natural variantiVAR_060305 | 715 | N → Y. Corresponds to variant dbSNP:rs7523552Ensembl. | 1 | |
Natural variantiVAR_060306 | 826 | K → E. Corresponds to variant dbSNP:rs3738439Ensembl. | 1 | |
Natural variantiVAR_060307 | 945 | N → S. Corresponds to variant dbSNP:rs560389Ensembl. | 1 | |
Natural variantiVAR_060308 | 1048 | N → T. Corresponds to variant dbSNP:rs565156Ensembl. | 1 | |
Natural variantiVAR_060309 | 1083 | F → V. Corresponds to variant dbSNP:rs17578364Ensembl. | 1 | |
Natural variantiVAR_060310 | 1158 | V → I. Corresponds to variant dbSNP:rs566576Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_031737 | 1256 – 1259 | DIDD → NVQK in isoform 2. 1 Publication | 4 | |
Alternative sequenceiVSP_031738 | 1260 – 1409 | Missing in isoform 2. 1 PublicationAdd BLAST | 150 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC104836 Genomic DNA. No translation available. AF017090 mRNA. Translation: AAC28132.1. Different initiation. AB029030 mRNA. Translation: BAA83059.1. BC037317 mRNA. Translation: AAH37317.2. |
RefSeqi | NP_056052.3. NM_015237.3. |
UniGenei | Hs.21554. |
Genome annotation databases
Ensembli | ENST00000409154; ENSP00000386957; ENSG00000069712. |
GeneIDi | 23285. |
KEGGi | hsa:23285. |
Keywords - Coding sequence diversityi
Alternative splicing, PolymorphismSimilar proteinsi
Entry informationi
Entry namei | K1107_HUMAN | |
Accessioni | Q9UPP5Primary (citable) accession number: Q9UPP5 Secondary accession number(s): O14767, Q8N3X7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 26, 2008 |
Last sequence update: | February 26, 2008 | |
Last modified: | March 28, 2018 | |
This is version 93 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |