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Q9UPP2

- IQEC3_HUMAN

UniProt

Q9UPP2 - IQEC3_HUMAN

Protein

IQ motif and SEC7 domain-containing protein 3

Gene

IQSEC3

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
    • BLAST
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    • History
      Entry version 105 (01 Oct 2014)
      Sequence version 3 (25 Nov 2008)
      Previous versions | rss
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    Functioni

    Acts as a guanine nucleotide exchange factor (GEF) for ARF1.1 Publication

    GO - Molecular functioni

    1. ARF guanyl-nucleotide exchange factor activity Source: RefGenome

    GO - Biological processi

    1. actin cytoskeleton organization Source: RefGenome
    2. positive regulation of GTPase activity Source: GOC
    3. regulation of ARF protein signal transduction Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    IQ motif and SEC7 domain-containing protein 3
    Gene namesi
    Name:IQSEC3
    Synonyms:KIAA1110
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 12

    Organism-specific databases

    HGNCiHGNC:29193. IQSEC3.

    Subcellular locationi

    Cytoplasm 1 Publication

    GO - Cellular componenti

    1. cell junction Source: RefGenome
    2. cytoplasm Source: UniProtKB-SubCell
    3. inhibitory synapse Source: Ensembl
    4. postsynaptic membrane Source: Ensembl

    Keywords - Cellular componenti

    Cytoplasm

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134990290.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 11821182IQ motif and SEC7 domain-containing protein 3PRO_0000245610Add
    BLAST

    Proteomic databases

    PaxDbiQ9UPP2.
    PRIDEiQ9UPP2.

    PTM databases

    PhosphoSiteiQ9UPP2.

    Expressioni

    Tissue specificityi

    Expressed specifically in the adult brain, predominantly in the cerebral cortex and the olfactory bulb, but not in the fetal brain. Expressed only in mature neurons, but not in undifferentiated neural stem precursor cells (NSPCs), nor in glioma cells.1 Publication

    Gene expression databases

    BgeeiQ9UPP2.
    CleanExiHS_IQSEC3.
    GenevestigatoriQ9UPP2.

    Organism-specific databases

    HPAiHPA039025.

    Interactioni

    Subunit structurei

    Interacts with DLG1 and DLG4.By similarity

    Protein-protein interaction databases

    STRINGi9606.ENSP00000372292.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9UPP2.
    SMRiQ9UPP2. Positions 645-996.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini315 – 34430IQPROSITE-ProRule annotationAdd
    BLAST
    Domaini644 – 837194SEC7PROSITE-ProRule annotationAdd
    BLAST
    Domaini850 – 983134PHAdd
    BLAST

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili20 – 5637Sequence AnalysisAdd
    BLAST
    Coiled coili964 – 99229Sequence AnalysisAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi78 – 9013Poly-AlaAdd
    BLAST
    Compositional biasi225 – 2317Poly-Ala
    Compositional biasi248 – 2514Poly-Glu
    Compositional biasi572 – 5798Poly-Glu
    Compositional biasi598 – 6036Poly-Ser
    Compositional biasi1061 – 1165105Pro-richAdd
    BLAST

    Sequence similaritiesi

    Belongs to the BRAG family.Curated
    Contains 1 IQ domain.PROSITE-ProRule annotation
    Contains 1 PH domain.Curated
    Contains 1 SEC7 domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Coiled coil

    Phylogenomic databases

    eggNOGiCOG5307.
    HOGENOMiHOG000113099.
    HOVERGENiHBG056324.
    InParanoidiQ9UPP2.
    KOiK12495.
    OMAiQTYQHNS.
    OrthoDBiEOG7SR4KP.
    PhylomeDBiQ9UPP2.
    TreeFamiTF323811.

    Family and domain databases

    Gene3Di1.10.1000.11. 1 hit.
    2.30.29.30. 1 hit.
    InterProiIPR000048. IQ_motif_EF-hand-BS.
    IPR001849. PH_domain.
    IPR011993. PH_like_dom.
    IPR023394. Sec7_alpha_orthog.
    IPR000904. Sec7_dom.
    [Graphical view]
    PfamiPF01369. Sec7. 1 hit.
    [Graphical view]
    SMARTiSM00233. PH. 1 hit.
    SM00222. Sec7. 1 hit.
    [Graphical view]
    SUPFAMiSSF48425. SSF48425. 1 hit.
    PROSITEiPS50096. IQ. 1 hit.
    PS50190. SEC7. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q9UPP2-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MESLLENPVR AVLYLKELTA IVQNQQSLIH TQRERIDELE RRLDELSAEN     50
    RSLWEHQQLL QAQPPPGLVP PSSAPLPAAP ATAPAAAARA QEPLQDQGQR 100
    SAAAPHPAPD RPPRQHHGQL LEQPQRGPGS RAHTPQSPHK HLGTQGAVTD 150
    KEKERPPSCC AAAGALLQHK SPSALGKGVL SRRPENETVL HQFCCPAADA 200
    CSDLASQSDG SCTQAGGGME DSVVAAAAVA AGRPSAHAPK AQAQELQEEE 250
    ERPGAGAASP RAGPQHKASP GRQQPALATA LCPHAPAASD YELSLDLKNK 300
    QIEMLEHKYG GHLVSRRAAC TIQTAFRQYQ LSKNFEKIRN SLLESRLPRR 350
    ISLRKVRSPT AESLAAEKAL MEGYGLVGLP LVRSPSLPPT FAGTLTELED 400
    SFTEQVQSLA KSIDDALSTW SLKTMCSLRE SGAYQLHQAL QAAAGPPGLE 450
    AEGRAPESAG PGPGDDAAET PGLPPAHSGT LMMAFRDVTV QIANQNISVS 500
    SSTALSVANC LGAQTVQAPA EPAAGKAEQG ETSGREAPEA PAVGREDASA 550
    EDSCAEAAAS GAADGATAPK TEEEEEEEET AEVGRGAEAE AGDLEQLSSS 600
    STSTKSAKSG SEASASASKD ALQAMILSLP RYHCENPASC KSPTLSTDTL 650
    RKRLYRIGLN LFNINPDKGI QFLISRGFIP DTPIGVAHFL LQRKGLSRQM 700
    IGEFLGNSKK QFNRDVLDCV VDEMDFSSME LDEALRKFQA HIRVQGEAQK 750
    VERLIEAFSQ RYCMCNPEVV QQFHNPDTIF ILAFAIILLN TDMYSPNIKP 800
    DRKMMLEDFI RNLRGVDDGA DIPRELVVGI YERIQQKELK SNEDHVTYVT 850
    KVEKSIVGMK TVLSVPHRRL VCCSRLFEVT DVNKLQKQAA HQREVFLFND 900
    LLVILKLCPK KKSSSTYTFC KSVGLLGMQF QLFENEYYSH GITLVTPLSG 950
    SEKKQVLHFC ALGSDEMQKF VEDLKESIAE VTELEQIRIE WELEKQQGTK 1000
    TLSFKPCGAQ GDPQSKQGSP TAKREAALRE RPAESTVEVS IHNRLQTSQH 1050
    NSGLGAERGA PVPPPDLQPS PPRQQTPPLP PPPPTPPGTL VQCQQIVKVI 1100
    VLDKPCLARM EPLLSQALSC YTSSSSDSCG STPLGGPGSP VKVTHQPPLP 1150
    PPPPPYNHPH QFCPPGSLLH GHRYSSGSRS LV 1182
    Length:1,182
    Mass (Da):127,621
    Last modified:November 25, 2008 - v3
    Checksum:iCA03171E62C19E07
    GO
    Isoform 2 (identifier: Q9UPP2-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-303: Missing.
         1040-1062: SIHNRLQTSQHNSGLGAERGAPV → LINASPARLTILPISRDTIKSYC
         1063-1182: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:759
    Mass (Da):83,143
    Checksum:i38426830313647B9
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti31 – 311T → S in AAH24764. (PubMed:15489334)Curated
    Sequence conflicti283 – 2831P → S in BC042067. (PubMed:15489334)Curated
    Sequence conflicti397 – 3971E → K in AK091953. (PubMed:14702039)Curated
    Sequence conflicti465 – 4651D → G in BAA83062. (PubMed:10470851)Curated
    Sequence conflicti476 – 4761A → T in AK091953. (PubMed:14702039)Curated
    Sequence conflicti514 – 5141Q → H in AK091953. (PubMed:14702039)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti558 – 5581A → G.1 Publication
    Corresponds to variant rs56204927 [ dbSNP | Ensembl ].
    VAR_061789

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 303303Missing in isoform 2. 1 PublicationVSP_035695Add
    BLAST
    Alternative sequencei1040 – 106223SIHNR…RGAPV → LINASPARLTILPISRDTIK SYC in isoform 2. 1 PublicationVSP_035696Add
    BLAST
    Alternative sequencei1063 – 1182120Missing in isoform 2. 1 PublicationVSP_035697Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK091953 mRNA. No translation available.
    AC007406 Genomic DNA. No translation available.
    AC026369 Genomic DNA. No translation available.
    BC024764 mRNA. Translation: AAH24764.1.
    BC042067 mRNA. No translation available.
    AB029033 mRNA. Translation: BAA83062.1.
    CCDSiCCDS31725.1. [Q9UPP2-2]
    CCDS53728.1. [Q9UPP2-1]
    RefSeqiNP_001164209.1. NM_001170738.1. [Q9UPP2-1]
    NP_056047.1. NM_015232.1. [Q9UPP2-2]
    UniGeneiHs.536319.

    Genome annotation databases

    EnsembliENST00000382841; ENSP00000372292; ENSG00000120645. [Q9UPP2-2]
    ENST00000538872; ENSP00000437554; ENSG00000120645. [Q9UPP2-1]
    ENST00000571363; ENSP00000461043; ENSG00000262607. [Q9UPP2-2]
    ENST00000575724; ENSP00000461496; ENSG00000262607. [Q9UPP2-1]
    GeneIDi440073.
    KEGGihsa:440073.
    UCSCiuc001qhu.1. human. [Q9UPP2-2]
    uc001qhw.2. human. [Q9UPP2-1]

    Polymorphism databases

    DMDMi215274117.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK091953 mRNA. No translation available.
    AC007406 Genomic DNA. No translation available.
    AC026369 Genomic DNA. No translation available.
    BC024764 mRNA. Translation: AAH24764.1 .
    BC042067 mRNA. No translation available.
    AB029033 mRNA. Translation: BAA83062.1 .
    CCDSi CCDS31725.1. [Q9UPP2-2 ]
    CCDS53728.1. [Q9UPP2-1 ]
    RefSeqi NP_001164209.1. NM_001170738.1. [Q9UPP2-1 ]
    NP_056047.1. NM_015232.1. [Q9UPP2-2 ]
    UniGenei Hs.536319.

    3D structure databases

    ProteinModelPortali Q9UPP2.
    SMRi Q9UPP2. Positions 645-996.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9606.ENSP00000372292.

    PTM databases

    PhosphoSitei Q9UPP2.

    Polymorphism databases

    DMDMi 215274117.

    Proteomic databases

    PaxDbi Q9UPP2.
    PRIDEi Q9UPP2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000382841 ; ENSP00000372292 ; ENSG00000120645 . [Q9UPP2-2 ]
    ENST00000538872 ; ENSP00000437554 ; ENSG00000120645 . [Q9UPP2-1 ]
    ENST00000571363 ; ENSP00000461043 ; ENSG00000262607 . [Q9UPP2-2 ]
    ENST00000575724 ; ENSP00000461496 ; ENSG00000262607 . [Q9UPP2-1 ]
    GeneIDi 440073.
    KEGGi hsa:440073.
    UCSCi uc001qhu.1. human. [Q9UPP2-2 ]
    uc001qhw.2. human. [Q9UPP2-1 ]

    Organism-specific databases

    CTDi 440073.
    GeneCardsi GC12P000176.
    HGNCi HGNC:29193. IQSEC3.
    HPAi HPA039025.
    MIMi 612118. gene.
    neXtProti NX_Q9UPP2.
    PharmGKBi PA134990290.
    HUGEi Search...
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG5307.
    HOGENOMi HOG000113099.
    HOVERGENi HBG056324.
    InParanoidi Q9UPP2.
    KOi K12495.
    OMAi QTYQHNS.
    OrthoDBi EOG7SR4KP.
    PhylomeDBi Q9UPP2.
    TreeFami TF323811.

    Miscellaneous databases

    ChiTaRSi IQSEC3. human.
    GenomeRNAii 440073.
    NextBioi 108902.
    PROi Q9UPP2.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q9UPP2.
    CleanExi HS_IQSEC3.
    Genevestigatori Q9UPP2.

    Family and domain databases

    Gene3Di 1.10.1000.11. 1 hit.
    2.30.29.30. 1 hit.
    InterProi IPR000048. IQ_motif_EF-hand-BS.
    IPR001849. PH_domain.
    IPR011993. PH_like_dom.
    IPR023394. Sec7_alpha_orthog.
    IPR000904. Sec7_dom.
    [Graphical view ]
    Pfami PF01369. Sec7. 1 hit.
    [Graphical view ]
    SMARTi SM00233. PH. 1 hit.
    SM00222. Sec7. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48425. SSF48425. 1 hit.
    PROSITEi PS50096. IQ. 1 hit.
    PS50190. SEC7. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    2. "The finished DNA sequence of human chromosome 12."
      Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.
      , Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J.H., Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., Perrin W., Pickens A., Primus E.L., Pu L.-L., Puazo M., Quiles M.M., Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G., Gibbs R.A.
      Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Tissue: Brain.
    4. "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
      Kikuno R., Nagase T., Ishikawa K., Hirosawa M., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O.
      DNA Res. 6:197-205(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 443-1182 (ISOFORM 1), VARIANT GLY-558.
      Tissue: Brain.
    5. "Identification of a neuron-specific human gene, KIAA1110, that is a guanine nucleotide exchange factor for ARF1."
      Hattori Y., Ohta S., Hamada K., Yamada-Okabe H., Kanemura Y., Matsuzaki Y., Okano H., Kawakami Y., Toda M.
      Biochem. Biophys. Res. Commun. 364:737-742(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.

    Entry informationi

    Entry nameiIQEC3_HUMAN
    AccessioniPrimary (citable) accession number: Q9UPP2
    Secondary accession number(s): A6NIF2, A6NKV9, Q8TB43
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 11, 2006
    Last sequence update: November 25, 2008
    Last modified: October 1, 2014
    This is version 105 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 12
      Human chromosome 12: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3