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Q9UPJ8

- Q9UPJ8_HUMAN

UniProt

Q9UPJ8 - Q9UPJ8_HUMAN

Protein
Submitted name:

PkB-like

Gene

PkB-like 1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 86 (01 Oct 2014)
      Sequence version 1 (01 May 2000)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. 3-phosphoinositide-dependent protein kinase activity Source: Ensembl
    2. ATP binding Source: UniProtKB-KW

    GO - Biological processi

    1. focal adhesion assembly Source: Ensembl
    2. hyperosmotic response Source: Ensembl
    3. negative regulation of cardiac muscle cell apoptotic process Source: Ensembl
    4. negative regulation of toll-like receptor signaling pathway Source: Ensembl
    5. regulation of endothelial cell migration Source: Ensembl
    6. regulation of mast cell degranulation Source: Ensembl
    7. type B pancreatic cell development Source: Ensembl

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    SignaLinkiQ9UPJ8.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    PkB-likeImported
    Gene namesi
    Name:PkB-like 1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasmic membrane-bounded vesicle Source: Ensembl
    2. cytosol Source: Ensembl
    3. plasma membrane Source: Ensembl

    PTM / Processingi

    Proteomic databases

    PRIDEiQ9UPJ8.

    Expressioni

    Gene expression databases

    ArrayExpressiQ9UPJ8.
    BgeeiQ9UPJ8.

    Interactioni

    Structurei

    3D structure databases

    ProteinModelPortaliQ9UPJ8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG098357.

    Family and domain databases

    Gene3Di2.30.29.30. 1 hit.
    InterProiIPR011009. Kinase-like_dom.
    IPR011993. PH_like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF00069. Pkinase. 1 hit.
    [Graphical view]
    SMARTiSM00220. S_TKc. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q9UPJ8-1 [UniParc]FASTAAdd to Basket

    « Hide

    YDAVPIQSSV VLCSCPSPSM VRTQTESSTP PGIPGGSRQG PAMDGTAAEP    50
    RPGAGSLQHA QPPPQPRKKR PEDFKFGKIL GEGSFSTVVL ARELATSREY 100
    AIKILEKRHI IKENKVPYVT RERDVMSRLD HPFFVKLYFT FQDDEKLYFG 150
    LSYAKNGELL KYIRKIGSFD ETCTRFYTAE IVSALEYLHG KGIIHRDLKP 200
    ENILLNEDMH IQITDFGTAK VLSPESKQAR ANSFVGTAQY VSPELLTEKS 250
    ACKSSDLWAL GCIIYQLVAG LPPFRAGNEY LIFQKIIKLE YDFPEKFFPK 300
    ARDLVEKLLV LDATKRLGCE EMEGYGPLKA HPFFESVTWE NLHQQTPPKL 350
    TAYLPAMSED DEDCYGN 367
    Length:367
    Mass (Da):41,299
    Last modified:May 1, 2000 - v1
    Checksum:i261CDF0075587493
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei367 – 3671Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC005591 Genomic DNA. Translation: AAC33797.1.
    UniGeneiHs.459691.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC005591 Genomic DNA. Translation: AAC33797.1 .
    UniGenei Hs.459691.

    3D structure databases

    ProteinModelPortali Q9UPJ8.
    ModBasei Search...
    MobiDBi Search...

    Chemistry

    BindingDBi Q9UPJ8.

    Proteomic databases

    PRIDEi Q9UPJ8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG098357.

    Enzyme and pathway databases

    SignaLinki Q9UPJ8.

    Gene expression databases

    ArrayExpressi Q9UPJ8.
    Bgeei Q9UPJ8.

    Family and domain databases

    Gene3Di 2.30.29.30. 1 hit.
    InterProi IPR011009. Kinase-like_dom.
    IPR011993. PH_like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SMARTi SM00220. S_TKc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Large Scale Sequence Analysis and Annotation with the Sequence Comparison Analysis (SCAN) System."
      Ricke D.O.
      Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    2. Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ9UPJ8_HUMAN
    AccessioniPrimary (citable) accession number: Q9UPJ8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 1, 2000
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 86 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.