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Q9UPJ8

- Q9UPJ8_HUMAN

UniProt

Q9UPJ8 - Q9UPJ8_HUMAN

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Protein
Submitted name:

PkB-like

Gene

PkB-like 1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. 3-phosphoinositide-dependent protein kinase activity Source: Ensembl
  2. ATP binding Source: UniProtKB-KW

GO - Biological processi

  1. focal adhesion assembly Source: Ensembl
  2. hyperosmotic response Source: Ensembl
  3. negative regulation of cardiac muscle cell apoptotic process Source: Ensembl
  4. negative regulation of toll-like receptor signaling pathway Source: Ensembl
  5. regulation of endothelial cell migration Source: Ensembl
  6. regulation of mast cell degranulation Source: Ensembl
  7. type B pancreatic cell development Source: Ensembl
Complete GO annotation...

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

SignaLinkiQ9UPJ8.

Names & Taxonomyi

Protein namesi
Submitted name:
PkB-likeImported
Gene namesi
Name:PkB-like 1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. cytoplasmic membrane-bounded vesicle Source: Ensembl
  2. cytosol Source: Ensembl
  3. plasma membrane Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ9UPJ8.

Expressioni

Gene expression databases

BgeeiQ9UPJ8.
ExpressionAtlasiQ9UPJ8. baseline and differential.

Interactioni

Structurei

3D structure databases

ProteinModelPortaliQ9UPJ8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG098357.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
InterProiIPR011009. Kinase-like_dom.
IPR011993. PH_like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9UPJ8 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
YDAVPIQSSV VLCSCPSPSM VRTQTESSTP PGIPGGSRQG PAMDGTAAEP
60 70 80 90 100
RPGAGSLQHA QPPPQPRKKR PEDFKFGKIL GEGSFSTVVL ARELATSREY
110 120 130 140 150
AIKILEKRHI IKENKVPYVT RERDVMSRLD HPFFVKLYFT FQDDEKLYFG
160 170 180 190 200
LSYAKNGELL KYIRKIGSFD ETCTRFYTAE IVSALEYLHG KGIIHRDLKP
210 220 230 240 250
ENILLNEDMH IQITDFGTAK VLSPESKQAR ANSFVGTAQY VSPELLTEKS
260 270 280 290 300
ACKSSDLWAL GCIIYQLVAG LPPFRAGNEY LIFQKIIKLE YDFPEKFFPK
310 320 330 340 350
ARDLVEKLLV LDATKRLGCE EMEGYGPLKA HPFFESVTWE NLHQQTPPKL
360
TAYLPAMSED DEDCYGN
Length:367
Mass (Da):41,299
Last modified:May 1, 2000 - v1
Checksum:i261CDF0075587493
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei367 – 3671Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC005591 Genomic DNA. Translation: AAC33797.1.
UniGeneiHs.459691.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC005591 Genomic DNA. Translation: AAC33797.1 .
UniGenei Hs.459691.

3D structure databases

ProteinModelPortali Q9UPJ8.
ModBasei Search...
MobiDBi Search...

Chemistry

BindingDBi Q9UPJ8.

Proteomic databases

PRIDEi Q9UPJ8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOVERGENi HBG098357.

Enzyme and pathway databases

SignaLinki Q9UPJ8.

Gene expression databases

Bgeei Q9UPJ8.
ExpressionAtlasi Q9UPJ8. baseline and differential.

Family and domain databases

Gene3Di 2.30.29.30. 1 hit.
InterProi IPR011009. Kinase-like_dom.
IPR011993. PH_like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00220. S_TKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Large Scale Sequence Analysis and Annotation with the Sequence Comparison Analysis (SCAN) System."
    Ricke D.O.
    Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ9UPJ8_HUMAN
AccessioniPrimary (citable) accession number: Q9UPJ8
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: October 29, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.