Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein bassoon

Gene

BSN

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Is thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act through binding to ERC2/CAST1. Essential in regulated neurotransmitter release from a subset of brain glutamatergic synapses. Involved in the formation of the retinal photoreceptor ribbon synapses (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri170 – 193C4-typeSequence analysisAdd BLAST24
Zinc fingeri198 – 220C4-typeSequence analysisAdd BLAST23
Zinc fingeri465 – 488C4-typeSequence analysisAdd BLAST24
Zinc fingeri493 – 515C4-typeSequence analysisAdd BLAST23

GO - Molecular functioni

GO - Biological processi

  • chemical synaptic transmission Source: ProtInc
  • protein localization to synapse Source: Ensembl
  • synapse assembly Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciZFISH:ENSG00000164061-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein bassoon
Alternative name(s):
Zinc finger protein 231
Gene namesi
Name:BSN
Synonyms:KIAA0434, ZNF231
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

HGNCiHGNC:1117. BSN.

Subcellular locationi

GO - Cellular componenti

  • axon Source: Ensembl
  • cell junction Source: UniProtKB-KW
  • cell surface Source: Ensembl
  • cytoskeleton of presynaptic active zone Source: ParkinsonsUK-UCL
  • dendrite Source: BHF-UCL
  • excitatory synapse Source: ParkinsonsUK-UCL
  • neuron projection terminus Source: Ensembl
  • nucleus Source: ProtInc
  • postsynaptic density Source: Ensembl
  • presynaptic active zone Source: ParkinsonsUK-UCL
Complete GO annotation...

Keywords - Cellular componenti

Cell junction, Cytoplasm, Cytoskeleton, Synapse, Synaptosome

Pathology & Biotechi

Organism-specific databases

DisGeNETi8927.
OpenTargetsiENSG00000164061.
PharmGKBiPA25434.

Polymorphism and mutation databases

BioMutaiBSN.
DMDMi229463040.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00000650022 – 3926Protein bassoonAdd BLAST3925

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi2N-myristoyl glycineBy similarity1
Modified residuei145PhosphoserineBy similarity1
Modified residuei148Omega-N-methylarginineBy similarity1
Modified residuei244PhosphoserineBy similarity1
Modified residuei248PhosphoserineBy similarity1
Modified residuei867Omega-N-methylarginineBy similarity1
Modified residuei970PhosphoserineBy similarity1
Modified residuei1040PhosphoserineBy similarity1
Modified residuei1041PhosphoserineBy similarity1
Modified residuei1090PhosphoserineBy similarity1
Modified residuei1092PhosphothreonineBy similarity1
Modified residuei1098PhosphoserineBy similarity1
Modified residuei1104PhosphoserineBy similarity1
Modified residuei1226PhosphoserineBy similarity1
Glycosylationi1343O-linked (GlcNAc)By similarity1
Glycosylationi1384O-linked (GlcNAc)By similarity1
Modified residuei1477PhosphoserineBy similarity1
Modified residuei1486PhosphoserineBy similarity1
Modified residuei1488PhosphoserineBy similarity1
Modified residuei1787Omega-N-methylarginineBy similarity1
Modified residuei1791Omega-N-methylarginineBy similarity1
Modified residuei1801Asymmetric dimethylarginine; alternateBy similarity1
Modified residuei1801Omega-N-methylarginine; alternateBy similarity1
Modified residuei1813Omega-N-methylarginineBy similarity1
Modified residuei1985PhosphoserineBy similarity1
Modified residuei2041PhosphoserineBy similarity1
Modified residuei2046Omega-N-methylarginineBy similarity1
Modified residuei2076Omega-N-methylarginineBy similarity1
Modified residuei2250Asymmetric dimethylarginineBy similarity1
Modified residuei2260Asymmetric dimethylarginineBy similarity1
Modified residuei2266Asymmetric dimethylarginineBy similarity1
Glycosylationi2314O-linked (GlcNAc)By similarity1
Modified residuei2570PhosphoserineBy similarity1
Modified residuei2587PhosphothreonineBy similarity1
Modified residuei2614PhosphothreonineBy similarity1
Glycosylationi2691O-linked (GlcNAc)By similarity1
Modified residuei2802PhosphoserineBy similarity1
Modified residuei2851PhosphoserineBy similarity1
Modified residuei2857PhosphoserineBy similarity1
Glycosylationi2936O-linked (GlcNAc)By similarity1
Modified residuei3013PhosphoserineBy similarity1
Modified residuei3291PhosphoserineBy similarity1
Modified residuei3373PhosphoserineBy similarity1
Modified residuei3492Omega-N-methylarginineBy similarity1
Modified residuei3808Omega-N-methylarginineBy similarity1

Post-translational modificationi

Myristoylated. The N-terminal myristoylation is not sufficient for presynaptic localization (By similarity).By similarity

Keywords - PTMi

Glycoprotein, Lipoprotein, Methylation, Myristate, Phosphoprotein

Proteomic databases

EPDiQ9UPA5.
MaxQBiQ9UPA5.
PaxDbiQ9UPA5.
PeptideAtlasiQ9UPA5.
PRIDEiQ9UPA5.

PTM databases

iPTMnetiQ9UPA5.
PhosphoSitePlusiQ9UPA5.
SwissPalmiQ9UPA5.

Expressioni

Tissue specificityi

Exclusively expressed in brain.1 Publication

Gene expression databases

BgeeiENSG00000164061.
CleanExiHS_BSN.
GenevisibleiQ9UPA5. HS.

Organism-specific databases

HPAiHPA034757.

Interactioni

Subunit structurei

Interacts with ERC2/CAST1, RIMS1 and UNC13A. Part of a complex consisting of ERC2, RIMS1 and BSN (By similarity).By similarity

Protein-protein interaction databases

BioGridi114441. 6 interactors.
IntActiQ9UPA5. 2 interactors.
STRINGi9606.ENSP00000296452.

Structurei

3D structure databases

ProteinModelPortaliQ9UPA5.
SMRiQ9UPA5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati571 – 57717
Repeati578 – 58427
Repeati585 – 59137

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni23 – 325 X 2 AA tandem repeats of P-G10
Regioni61 – 747 X 2 AA tandem repeats of P-GAdd BLAST14
Regioni571 – 5913 X 7 AA tandem repeats of K-A-S-P-[LQ]-[APS]-[KST]Add BLAST21

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1037 – 1092Sequence analysisAdd BLAST56
Coiled coili1181 – 1208Sequence analysisAdd BLAST28
Coiled coili1276 – 1294Sequence analysisAdd BLAST19
Coiled coili2351 – 2476Sequence analysisAdd BLAST126
Coiled coili2939 – 2981Sequence analysisAdd BLAST43

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi2600 – 2606Poly-Arg7
Compositional biasi2627 – 2632Poly-Arg6
Compositional biasi3775 – 3783Poly-Gln9

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri170 – 193C4-typeSequence analysisAdd BLAST24
Zinc fingeri198 – 220C4-typeSequence analysisAdd BLAST23
Zinc fingeri465 – 488C4-typeSequence analysisAdd BLAST24
Zinc fingeri493 – 515C4-typeSequence analysisAdd BLAST23

Keywords - Domaini

Coiled coil, Repeat, Zinc-finger

Phylogenomic databases

eggNOGiENOG410IGEH. Eukaryota.
ENOG410XX5R. LUCA.
GeneTreeiENSGT00620000087961.
HOGENOMiHOG000095267.
HOVERGENiHBG080934.
InParanoidiQ9UPA5.
OMAiPASSHYY.
OrthoDBiEOG091G0020.
PhylomeDBiQ9UPA5.
TreeFamiTF326082.

Family and domain databases

Gene3Di3.30.40.10. 2 hits.
InterProiIPR030627. Bsn.
IPR011011. Znf_FYVE_PHD.
IPR008899. Znf_piccolo.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PANTHERiPTHR14113:SF1. PTHR14113:SF1. 1 hit.
PfamiPF05715. zf-piccolo. 2 hits.
[Graphical view]
SUPFAMiSSF57903. SSF57903. 2 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9UPA5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNEVSLEGG AGDGPLPPGG AGPGPGPGPG PGAGKPPSAP AGGGQLPAAG
60 70 80 90 100
AARSTAVPPV PGPGPGPGPG PGPGSTSRRL DPKEPLGNQR AASPTPKQAS
110 120 130 140 150
ATTPGHESPR ETRAQGPAGQ EADGPRRTLQ VDSRTQRSGR SPSVSPDRGS
160 170 180 190 200
TPTSPYSVPQ IAPLPSSTLC PICKTSDLTS TPSQPNFNTC TQCHNKVCNQ
210 220 230 240 250
CGFNPNPHLT QVKEWLCLNC QMQRALGMDM TTAPRSKSQQ QLHSPALSPA
260 270 280 290 300
HSPAKQPLGK PDQERSRGPG GPQPGSRQAE TARATSVPGP AQAAAPPEVG
310 320 330 340 350
RVSPQPPQPT KPSTAEPRPP AGEAPAKSAT AVPAGLGATE QTQEGLTGKL
360 370 380 390 400
FGLGASLLTQ ASTLMSVQPE ADTQGQPAPS KGTPKIVFND ASKEAGPKPL
410 420 430 440 450
GSGPGPGPAP GAKTEPGARM GPGSGPGALP KTGGTTSPKH GRAEHQAASK
460 470 480 490 500
AAAKPKTMPK ERAICPLCQA ELNVGSKSPA NYNTCTTCRL QVCNLCGFNP
510 520 530 540 550
TPHLVEKTEW LCLNCQTKRL LEGSLGEPTP LPPPTSQQPP VGAPHRASGT
560 570 580 590 600
SPLKQKGPQG LGQPSGPLPA KASPLSTKAS PLPSKASPQA KPLRASEPSK
610 620 630 640 650
TPSSVQEKKT RVPTKAEPMP KPPPETTPTP ATPKVKSGVR RAEPATPVVK
660 670 680 690 700
AVPEAPKGGE AEDLVGKPYS QDASRSPQSL SDTGYSSDGI SSSQSEITGV
710 720 730 740 750
VQQEVEQLDS AGVTGPHPPS PSEIHKVGSS MRPLLQAQGL APSERSKPLS
760 770 780 790 800
SGTGEEQKQR PHSLSITPEA FDSDEELEDI LEEDEDSAEW RRRREQQDTA
810 820 830 840 850
ESSDDFGSQL RHDYVEDSSE GGLSPLPPQP PARAAELTDE DFMRRQILEM
860 870 880 890 900
SAEEDNLEED DTATSGRGLA KHGTQKGGPR PRPEPSQEPA ALPKRRLPHN
910 920 930 940 950
ATTGYEELLP EGGSAEATDG SGTLQGGLRR FKTIELNSTG SYGHELDLGQ
960 970 980 990 1000
GPDPSLDREP ELEMESLTGS PEDRSRGEHS STLPASTPSY TSGTSPTSLS
1010 1020 1030 1040 1050
SLEEDSDSSP SRRQRLEEAK QQRKARHRSH GPLLPTIEDS SEEEELREEE
1060 1070 1080 1090 1100
ELLREQEKMR EVEQQRIRST ARKTRRDKEE LRAQRRRERS KTPPSNLSPI
1110 1120 1130 1140 1150
EDASPTEELR QAAEMEELHR SSCSEYSPSP SLDSEAEALD GGPSRLYKSG
1160 1170 1180 1190 1200
SEYNLPTFMS LYSPTETPSG SSTTPSSGRP LKSAEEAYEE MMRKAELLQR
1210 1220 1230 1240 1250
QQGQAAGARG PHGGPSQPTG PRGLGSFEYQ DTTDREYGQA AQPAAEGTPA
1260 1270 1280 1290 1300
SLGAAVYEEI LQTSQSIVRM RQASSRDLAF AEDKKKEKQF LNAESAYMDP
1310 1320 1330 1340 1350
MKQNGGPLTP GTSPTQLAAP VSFSTPTSSD SSGGRVIPDV RVTQHFAKET
1360 1370 1380 1390 1400
QDPLKLHSSP ASPSSASKEI GMPFSQGPGT PATTAVAPCP AGLPRGYMTP
1410 1420 1430 1440 1450
ASPAGSERSP SPSSTAHSYG HSPTTANYGS QTEDLPQAPS GLAAAGRAAR
1460 1470 1480 1490 1500
EKPLSASDGE GGTPQPSRAY SYFASSSPPL SPSSPSESPT FSPGKMGPRA
1510 1520 1530 1540 1550
TAEFSTQTPS PAPASDMPRS PGAPTPSPMV AQGTQTPHRP STPRLVWQES
1560 1570 1580 1590 1600
SQEAPFMVIT LASDASSQTR MVHASASTSP LCSPTETQPT THGYSQTTPP
1610 1620 1630 1640 1650
SVSQLPPEPP GPPGFPRVPS AGADGPLALY GWGALPAENI SLCRISSVPG
1660 1670 1680 1690 1700
TSRVEPGPRT PGTAVVDLRT AVKPTPIILT DQGMDLTSLA VEARKYGLAL
1710 1720 1730 1740 1750
DPIPGRQSTA VQPLVINLNA QEHTFLATAT TVSITMASSV FMAQQKQPVV
1760 1770 1780 1790 1800
YGDPYQSRLD FGQGGGSPVC LAQVKQVEQA VQTAPYRSGP RGRPREAKFA
1810 1820 1830 1840 1850
RYNLPNQVAP LARRDVLITQ MGTAQSIGLK PGPVPEPGAE PHRATPAELR
1860 1870 1880 1890 1900
SHALPGARKP HTVVVQMGEG TAGTVTTLLP EEPAGALDLT GMRPESQLAC
1910 1920 1930 1940 1950
CDMVYKLPFG SSCTGTFHPA PSVPEKSMAD AAPPGQSSSP FYGPRDPEPP
1960 1970 1980 1990 2000
EPPTYRAQGV VGPGPHEEQR PYPQGLPGRL YSSMSDTNLA EAGLNYHAQR
2010 2020 2030 2040 2050
IGQLFQGPGR DSAMDLSSLK HSYSLGFADG RYLGQGLQYG SVTDLRHPTD
2060 2070 2080 2090 2100
LLAHPLPMRR YSSVSNIYSD HRYGPRGDAV GFQEASLAQY SATTAREISR
2110 2120 2130 2140 2150
MCAALNSMDQ YGGRHGSGGG GPDLVQYQPQ HGPGLSAPQS LVPLRPGLLG
2160 2170 2180 2190 2200
NPTFPEGHPS PGNLAQYGPA AGQGTAVRQL LPSTATVRAA DGMIYSTINT
2210 2220 2230 2240 2250
PIAATLPITT QPASVLRPMV RGGMYRPYAS GGITAVPLTS LTRVPMIAPR
2260 2270 2280 2290 2300
VPLGPTGLYR YPAPSRFPIA SSVPPAEGPV YLGKPAAAKA PGAGGPSRPE
2310 2320 2330 2340 2350
MPVGAAREEP LPTTTPAAIK EAAGAPAPAP LAGQKPPADA APGGGSGALS
2360 2370 2380 2390 2400
RPGFEKEEAS QEERQRKQQE QLLQLERERV ELEKLRQLRL QEELERERVE
2410 2420 2430 2440 2450
LQRHREEEQL LVQRELQELQ TIKHHVLQQQ QEERQAQFAL QREQLAQQRL
2460 2470 2480 2490 2500
QLEQIQQLQQ QLQQQLEEQK QRQKAPFPAA CEAPGRGPPL AAAELAQNGQ
2510 2520 2530 2540 2550
YWPPLTHAAF IAMAGPEGLG QPREPVLHRG LPSSASDMSL QTEEQWEASR
2560 2570 2580 2590 2600
SGIKKRHSMP RLRDACELES GTEPCVVRRI ADSSVQTDDE DGESRYLLSR
2610 2620 2630 2640 2650
RRRARRSADC SVQTDDEDSA EWEQPVRRRR SRLPRHSDSG SDSKHDATAS
2660 2670 2680 2690 2700
SSSAAATVRA MSSVGIQTIS DCSVQTEPDQ LPRVSPAIHI TAATDPKVEI
2710 2720 2730 2740 2750
VRYISAPEKT GRGESLACQT EPDGQAQGVA GPQLVGPTAI SPYLPGIQIV
2760 2770 2780 2790 2800
TPGPLGRFEK KKPDPLEIGY QAHLPPESLS QLVSRQPPKS PQVLYSPVSP
2810 2820 2830 2840 2850
LSPHRLLDTS FASSERLNKA HVSPQKHFTA DSALRQQTLP RPMKTLQRSL
2860 2870 2880 2890 2900
SDPKPLSPTA EESAKERFSL YQHQGGLGSQ VSALPPNSLV RKVKRTLPSP
2910 2920 2930 2940 2950
PPEEAHLPLA GQASPQLYAA SLLQRGLTGP TTVPATKASL LRELDRDLRL
2960 2970 2980 2990 3000
VEHESTKLRK KQAELDEEEK EIDAKLKYLE LGITQRKESL AKDRGGRDYP
3010 3020 3030 3040 3050
PLRGLGEHRD YLSDSELNQL RLQGCTTPAG QFVDFPATAA APATPSGPTA
3060 3070 3080 3090 3100
FQQPRFQPPA PQYSAGSGGP TQNGFPAHQA PTYPGPSTYP APAFPPGASY
3110 3120 3130 3140 3150
PAEPGLPNQQ AFRPTGHYAG QTPMPTTQST LFPVPADSRA PLQKPRQTSL
3160 3170 3180 3190 3200
ADLEQKVPTN YEVIASPVVP MSSAPSETSY SGPAVSSGYE QGKVPEVPRA
3210 3220 3230 3240 3250
GDRGSVSQSP APTYPSDSHY TSLEQNVPRN YVMIDDISEL TKDSTSTAPD
3260 3270 3280 3290 3300
SQRLEPLGPG SSGRPGKEPG EPGVLDGPTL PCCYARGEEE SEEDSYDPRG
3310 3320 3330 3340 3350
KGGHLRSMES NGRPASTHYY GDSDYRHGAR VEKYGPGPMG PKHPSKSLAP
3360 3370 3380 3390 3400
AAISSKRSKH RKQGMEQKIS KFSPIEEAKD VESDLASYPP PAVSSSLVSR
3410 3420 3430 3440 3450
GRKFQDEITY GLKKNVYEQQ KYYGMSSRDA VEDDRIYGGS SRSRAPSAYS
3460 3470 3480 3490 3500
GEKLSSHDFS GWGKGYERER EAVERLQKAG PKPSSLSMAH SRVRPPMRSQ
3510 3520 3530 3540 3550
ASEEESPVSP LGRPRPAGGP LPPGGDTCPQ FCSSHSMPDV QEHVKDGPRA
3560 3570 3580 3590 3600
HAYKREEGYI LDDSHCVVSD SEAYHLGQEE TDWFDKPRDA RSDRFRHHGG
3610 3620 3630 3640 3650
HAVSSSSQKR GPARHSYHDY DEPPEEGLWP HDEGGPGRHA SAKEHRHGDH
3660 3670 3680 3690 3700
GRHSGRHTGE EPGRRAAKPH ARDLGRHEAR PHSQPSSAPA MPKKGQPGYP
3710 3720 3730 3740 3750
SSAEYSQPSR ASSAYHHASD SKKGSRQAHS GPAALQSKAE PQAQPQLQGR
3760 3770 3780 3790 3800
QAAPGPQQSQ SPSSRQIPSG AASRQPQTQQ QQQGLGLQPP QQALTQARLQ
3810 3820 3830 3840 3850
QQSQPTTRGS APAASQPAGK PQPGPSTATG PQPAGPPRAE QTNGSKGTAK
3860 3870 3880 3890 3900
APQQGRAPQA QPAPGPGPAG VKAGARPGGT PGAPAGQPGA DGESVFSKIL
3910 3920
PGGAAEQAGK LTEAVSAFGK KFSSFW
Length:3,926
Mass (Da):416,469
Last modified:May 5, 2009 - v4
Checksum:i69B3AA86AD437356
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti3925F → L in AAC83555 (PubMed:9806829).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_055105741A → T.Corresponds to variant rs34762726dbSNPEnsembl.1
Natural variantiVAR_0551061213G → D.Corresponds to variant rs35762866dbSNPEnsembl.1
Natural variantiVAR_0551073863A → T.3 PublicationsCorresponds to variant rs2005557dbSNPEnsembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF052224 mRNA. Translation: AAC83555.1.
AC099668 Genomic DNA. No translation available.
AC104452 Genomic DNA. No translation available.
Y18448
, Y18449, Y18450, Y18451 Genomic DNA. Translation: CAA77176.1.
AB007894 mRNA. Translation: BAA23707.1.
CCDSiCCDS2800.1.
PIRiT00062.
RefSeqiNP_003449.2. NM_003458.3.
UniGeneiHs.194684.

Genome annotation databases

EnsembliENST00000296452; ENSP00000296452; ENSG00000164061.
GeneIDi8927.
KEGGihsa:8927.
UCSCiuc003cxe.5. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF052224 mRNA. Translation: AAC83555.1.
AC099668 Genomic DNA. No translation available.
AC104452 Genomic DNA. No translation available.
Y18448
, Y18449, Y18450, Y18451 Genomic DNA. Translation: CAA77176.1.
AB007894 mRNA. Translation: BAA23707.1.
CCDSiCCDS2800.1.
PIRiT00062.
RefSeqiNP_003449.2. NM_003458.3.
UniGeneiHs.194684.

3D structure databases

ProteinModelPortaliQ9UPA5.
SMRiQ9UPA5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi114441. 6 interactors.
IntActiQ9UPA5. 2 interactors.
STRINGi9606.ENSP00000296452.

PTM databases

iPTMnetiQ9UPA5.
PhosphoSitePlusiQ9UPA5.
SwissPalmiQ9UPA5.

Polymorphism and mutation databases

BioMutaiBSN.
DMDMi229463040.

Proteomic databases

EPDiQ9UPA5.
MaxQBiQ9UPA5.
PaxDbiQ9UPA5.
PeptideAtlasiQ9UPA5.
PRIDEiQ9UPA5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000296452; ENSP00000296452; ENSG00000164061.
GeneIDi8927.
KEGGihsa:8927.
UCSCiuc003cxe.5. human.

Organism-specific databases

CTDi8927.
DisGeNETi8927.
GeneCardsiBSN.
HGNCiHGNC:1117. BSN.
HPAiHPA034757.
MIMi604020. gene.
neXtProtiNX_Q9UPA5.
OpenTargetsiENSG00000164061.
PharmGKBiPA25434.
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IGEH. Eukaryota.
ENOG410XX5R. LUCA.
GeneTreeiENSGT00620000087961.
HOGENOMiHOG000095267.
HOVERGENiHBG080934.
InParanoidiQ9UPA5.
OMAiPASSHYY.
OrthoDBiEOG091G0020.
PhylomeDBiQ9UPA5.
TreeFamiTF326082.

Enzyme and pathway databases

BioCyciZFISH:ENSG00000164061-MONOMER.

Miscellaneous databases

ChiTaRSiBSN. human.
GenomeRNAii8927.
PROiQ9UPA5.
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000164061.
CleanExiHS_BSN.
GenevisibleiQ9UPA5. HS.

Family and domain databases

Gene3Di3.30.40.10. 2 hits.
InterProiIPR030627. Bsn.
IPR011011. Znf_FYVE_PHD.
IPR008899. Znf_piccolo.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PANTHERiPTHR14113:SF1. PTHR14113:SF1. 1 hit.
PfamiPF05715. zf-piccolo. 2 hits.
[Graphical view]
SUPFAMiSSF57903. SSF57903. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiBSN_HUMAN
AccessioniPrimary (citable) accession number: Q9UPA5
Secondary accession number(s): O43161, Q7LGH3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: May 5, 2009
Last modified: November 2, 2016
This is version 125 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.