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Q9UP87

- Q9UP87_HUMAN

UniProt

Q9UP87 - Q9UP87_HUMAN

Protein
Submitted name:

Type II interleukin-1 receptor antagonist

Gene

IL-1ra3

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 3 out of 5- Protein predictedi
  1. Functioni

    GO - Biological processi

    1. carboxylic acid metabolic process Source: Ensembl
    2. chronic inflammatory response to antigenic stimulus Source: Ensembl
    3. female pregnancy Source: Ensembl
    4. fever generation Source: Ensembl
    5. insulin secretion Source: Ensembl
    6. lipid metabolic process Source: Ensembl
    7. memory Source: Ensembl
    8. negative regulation of apoptotic process Source: Ensembl
    9. negative regulation of cell migration Source: Ensembl
    10. negative regulation of glutamate secretion Source: Ensembl
    11. negative regulation of membrane potential Source: Ensembl
    12. positive regulation of JUN kinase activity Source: Ensembl
    13. response to drug Source: Ensembl
    14. response to interleukin-4 Source: Ensembl
    15. response to lipopolysaccharide Source: Ensembl
    16. response to organic cyclic compound Source: Ensembl
    17. response to organonitrogen compound Source: Ensembl

    Keywords - Molecular functioni

    ReceptorImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Type II interleukin-1 receptor antagonistImported
    Gene namesi
    Name:IL-1ra3Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular space Source: Ensembl
    2. vesicle Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiQ9UP87.
    BgeeiQ9UP87.

    Sequencei

    Sequence statusi: Fragment.

    Q9UP87-1 [UniParc]FASTAAdd to Basket

    « Hide

    DLYEEGGGGG GEGEDNADSK                                    20
    Length:20
    Mass (Da):1,956
    Last modified:May 1, 2000 - v1
    Checksum:i47DDD28AE94667D6
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei20 – 201Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF057168 Genomic DNA. Translation: AAC13499.1.
    UniGeneiHs.81134.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF057168 Genomic DNA. Translation: AAC13499.1 .
    UniGenei Hs.81134.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    ChiTaRSi IL1RN. human.

    Gene expression databases

    ArrayExpressi Q9UP87.
    Bgeei Q9UP87.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Characterization of the type II intracellular IL-1 receptor antagonist (IL-1ra3): a depot IL-1ra without demonstrable intracellular function."
      Muzio M., Polentarutti N., Sironi M., Transidico P., Introna M., Mantovani A.
      Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ9UP87_HUMAN
    AccessioniPrimary (citable) accession number: Q9UP87
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 1, 2000
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 45 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.