Q9UP65 (PA24C_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytosolic phospholipase A2 gamma
Short name=cPLA2-gamma
EC=3.1.1.4

Alternative name(s):
Phospholipase A2 group IVC

Gene names

Name:

PLA2G4C

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	541 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Has a preference for arachidonic acid at the sn-2 position of phosphatidylcholine as compared with palmitic acid. Ref.2
Catalytic activity	Phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate.
Enzyme regulation	Not regulated by calcium.
Subcellular location	Membrane; Lipid-anchor Ref.2.
Tissue specificity	Highly expressed in heart and skeletal muscle. Ref.1 Ref.2
Sequence similarities	Contains 1 PLA2c domain.
Biophysicochemical properties	Kinetic parameters: Vmax=218 pmol/min/mg enzyme Ref.2

Ontologies

Keywords
Biological process	Lipid degradation Lipid metabolism
Cellular component	Membrane
Coding sequence diversity	Alternative splicing Polymorphism
Molecular function	Hydrolase
PTM	Lipoprotein Methylation Prenylation
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	arachidonic acid metabolic process Non-traceable author statement Ref.2. Source: UniProtKB glycerophospholipid biosynthetic process Traceable author statement. Source: Reactome glycerophospholipid catabolic process Inferred from direct assay Ref.2. Source: UniProtKB inflammatory response Non-traceable author statement Ref.2. Source: UniProtKB intracellular signal transduction Non-traceable author statement Ref.2. Source: UniProtKB parturition Non-traceable author statement Ref.2. Source: UniProtKB phosphatidylcholine acyl-chain remodeling Traceable author statement. Source: Reactome phosphatidylethanolamine acyl-chain remodeling Traceable author statement. Source: Reactome phosphatidylinositol acyl-chain remodeling Traceable author statement. Source: Reactome
Cellular_component	cytosol Traceable author statement Ref.2. Source: UniProtKB endoplasmic reticulum membrane Traceable author statement. Source: Reactome
Molecular_function	calcium-independent phospholipase A2 activity Inferred from direct assay Ref.2. Source: UniProtKB phospholipid binding Non-traceable author statement Ref.2. Source: UniProtKB
Complete GO annotation...

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q9UP65-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q9UP65-2)

The sequence of this isoform differs from the canonical sequence as follows:
     528-541: Missing.

Isoform 3 (identifier: Q9UP65-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-13: MGSSEVSIIPGLQ → MRTRPRPRLRRTENFLTAVHHGK

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 538	538	Cytosolic phospholipase A2 gamma		PRO_0000022995
	Propeptide	539 – 541	3	Removed in mature form		PRO_0000022996
Regions
	Domain	1 – 541	541	PLA2c
Sites
	Active site	82	1	Nucleophile By similarity
	Active site	385	1	Proton acceptor By similarity
Amino acid modifications
	Modified residue	538	1	Cysteine methyl ester Ref.11
	Lipidation	538	1	S-farnesyl cysteine Ref.11
Natural variations
	Alternative sequence	1 – 13	13	MGSSE…IPGLQ → MRTRPRPRLRRTENFLTAVH HGK in isoform 3.		VSP_045849
	Alternative sequence	528 – 541	14	Missing in isoform 2.		VSP_045850
	Natural variant	21	1	E → K. Ref.3 Corresponds to variant rs11564522 [ dbSNP | Ensembl ].		VAR_018761
	Natural variant	38	1	A → P. Ref.3 Corresponds to variant rs2307279 [ dbSNP | Ensembl ].		VAR_018420
	Natural variant	127	1	A → V. Ref.3 Corresponds to variant rs11564532 [ dbSNP | Ensembl ].		VAR_018762
	Natural variant	142	1	V → F. Ref.3 Corresponds to variant rs11564534 [ dbSNP | Ensembl ].		VAR_018763
	Natural variant	143	1	I → V. Ref.3 Ref.4 Corresponds to variant rs2303744 [ dbSNP | Ensembl ].		VAR_018421
	Natural variant	148	1	R → G. Ref.3 Corresponds to variant rs2307282 [ dbSNP | Ensembl ].		VAR_018764
	Natural variant	151	1	P → L. Ref.3 Corresponds to variant rs11564538 [ dbSNP | Ensembl ].		VAR_018765
	Natural variant	203	1	S → P. Ref.2 Ref.3 Ref.4 Ref.5 Corresponds to variant rs156631 [ dbSNP | Ensembl ].		VAR_018422
	Natural variant	226	1	T → S. Ref.3 Corresponds to variant rs11564541 [ dbSNP | Ensembl ].		VAR_018766
	Natural variant	360	1	T → P. Ref.3 Corresponds to variant rs11564620 [ dbSNP | Ensembl ].		VAR_018767
	Natural variant	411	1	D → N. Ref.3 Corresponds to variant rs11564638 [ dbSNP | Ensembl ].		VAR_018768
	Natural variant	430	1	R → C. Ref.9		VAR_018423
Experimental info
	Mutagenesis	54	1	R → A: Abolishes enzyme activity. Ref.2
	Mutagenesis	82	1	S → A: Abolishes enzyme activity. Ref.2
	Mutagenesis	385	1	D → A: Abolishes enzyme activity. Ref.2
	Mutagenesis	402	1	R → A: Abolishes enzyme activity. Ref.2
	Sequence conflict	24	1	R → G in BAG58352. Ref.4
	Sequence conflict	465	1	M → I in AAC32823. Ref.1
	Sequence conflict	480	1	E → G in CAG33097. Ref.5

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified February 8, 2011. Version 2. Checksum: A114B2A614EA4632	FASTA	541	60,939
	10 20 30 40 50 60 MGSSEVSIIP GLQKEEKAAV ERRRLHVLKA LKKLRIEADE APVVAVLGSG GGLRAHIACL 70 80 90 100 110 120 GVLSEMKEQG LLDAVTYLAG VSGSTWAISS LYTNDGDMEA LEADLKHRFT RQEWDLAKSL 130 140 150 160 170 180 QKTIQAARSE NYSLTDFWAY MVISKQTREL PESHLSNMKK PVEEGTLPYP IFAAIDNDLQ 190 200 210 220 230 240 PSWQEARAPE TWFEFTPHHA GFSALGAFVS ITHFGSKFKK GRLVRTHPER DLTFLRGLWG 250 260 270 280 290 300 SALGNTEVIR EYIFDQLRNL TLKGLWRRAV ANAKSIGHLI FARLLRLQES SQGEHPPPED 310 320 330 340 350 360 EGGEPEHTWL TEMLENWTRT SLEKQEQPHE DPERKGSLSN LMDFVKKTGI CASKWEWGTT 370 380 390 400 410 420 HNFLYKHGGI RDKIMSSRKH LHLVDAGLAI NTPFPLVLPP TREVHLILSF DFSAGDPFET 430 440 450 460 470 480 IRATTDYCRR HKIPFPQVEE AELDLWSKAP ASCYILKGET GPVVMHFPLF NIDACGGDIE 490 500 510 520 530 540 AWSDTYDTFK LADTYTLDVV VLLLALAKKN VRENKKKILR ELMNVAGLYY PKDSARSCCL A
	Isoform 2 [UniParc]. Checksum: 4F4C4884DE7EAD3A	FASTA	527	59,367
	10 20 30 40 50 60 MGSSEVSIIP GLQKEEKAAV ERRRLHVLKA LKKLRIEADE APVVAVLGSG GGLRAHIACL 70 80 90 100 110 120 GVLSEMKEQG LLDAVTYLAG VSGSTWAISS LYTNDGDMEA LEADLKHRFT RQEWDLAKSL 130 140 150 160 170 180 QKTIQAARSE NYSLTDFWAY MVISKQTREL PESHLSNMKK PVEEGTLPYP IFAAIDNDLQ 190 200 210 220 230 240 PSWQEARAPE TWFEFTPHHA GFSALGAFVS ITHFGSKFKK GRLVRTHPER DLTFLRGLWG 250 260 270 280 290 300 SALGNTEVIR EYIFDQLRNL TLKGLWRRAV ANAKSIGHLI FARLLRLQES SQGEHPPPED 310 320 330 340 350 360 EGGEPEHTWL TEMLENWTRT SLEKQEQPHE DPERKGSLSN LMDFVKKTGI CASKWEWGTT 370 380 390 400 410 420 HNFLYKHGGI RDKIMSSRKH LHLVDAGLAI NTPFPLVLPP TREVHLILSF DFSAGDPFET 430 440 450 460 470 480 IRATTDYCRR HKIPFPQVEE AELDLWSKAP ASCYILKGET GPVVMHFPLF NIDACGGDIE 490 500 510 520 AWSDTYDTFK LADTYTLDVV VLLLALAKKN VRENKKKILR ELMNVAG
	Isoform 3 [UniParc]. Checksum: D9A68B760776F943	FASTA	551	62,451
	10 20 30 40 50 60 MRTRPRPRLR RTENFLTAVH HGKKEEKAAV ERRRLHVLKA LKKLRIEADE APVVAVLGSG 70 80 90 100 110 120 GGLRAHIACL GVLSEMKEQG LLDAVTYLAG VSGSTWAISS LYTNDGDMEA LEADLKHRFT 130 140 150 160 170 180 RQEWDLAKSL QKTIQAARSE NYSLTDFWAY MVISKQTREL PESHLSNMKK PVEEGTLPYP 190 200 210 220 230 240 IFAAIDNDLQ PSWQEARAPE TWFEFTPHHA GFSALGAFVS ITHFGSKFKK GRLVRTHPER 250 260 270 280 290 300 DLTFLRGLWG SALGNTEVIR EYIFDQLRNL TLKGLWRRAV ANAKSIGHLI FARLLRLQES 310 320 330 340 350 360 SQGEHPPPED EGGEPEHTWL TEMLENWTRT SLEKQEQPHE DPERKGSLSN LMDFVKKTGI 370 380 390 400 410 420 CASKWEWGTT HNFLYKHGGI RDKIMSSRKH LHLVDAGLAI NTPFPLVLPP TREVHLILSF 430 440 450 460 470 480 DFSAGDPFET IRATTDYCRR HKIPFPQVEE AELDLWSKAP ASCYILKGET GPVVMHFPLF 490 500 510 520 530 540 NIDACGGDIE AWSDTYDTFK LADTYTLDVV VLLLALAKKN VRENKKKILR ELMNVAGLYY 550 PKDSARSCCL A

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A novel calcium-independent phospholipase A2, cPLA2-gamma, that is prenylated and contains homology to cPLA2." Underwood K.W., Song C., Kriz R.W., Chang X.J., Knopf J.L., Lin L.L. J. Biol. Chem. 273:21926-21932(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), CHARACTERIZATION, TISSUE SPECIFICITY. Tissue: Skeletal muscle.
[2]	"Molecular cloning of two new human paralogs of 85-kDa cytosolic phospholipase A2." Pickard R.T., Strifler B.A., Kramer R.M., Sharp J.D. J. Biol. Chem. 274:8823-8831(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, BIOPHYSICOCHEMICAL PROPERTIES, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, MUTAGENESIS OF ARG-54; SER-82; ASP-385 AND ARG-402, VARIANT PRO-203.
[3]	NIEHS SNPs program Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANTS LYS-21; PRO-38; VAL-127; PHE-142; VAL-143; GLY-148; LEU-151; PRO-203; SER-226; PRO-360 AND ASN-411.
[4]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3), VARIANTS VAL-143 AND PRO-203. Tissue: Corpus callosum and Tongue.
[5]	"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)." Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B. Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT PRO-203.
[6]	"The DNA sequence and biology of human chromosome 19." Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V. , Caoile C., Chan Y.M., Christensen M., Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., Rubin E.M., Lucas S.M. Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[7]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[8]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Tissue: Pancreas.
[9]	"SNP search of PLA2G4C gene." Koyama K.S., Kimura T., Imai T. Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 420-476, VARIANT CYS-430.
[10]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 443-541 (ISOFORM 1). Tissue: Uterus.
[11]	"Purification of recombinant human cPLA2 gamma and identification of C-terminal farnesylation, proteolytic processing, and carboxymethylation by MALDI-TOF-TOF analysis." Jenkins C.M., Han X., Yang J., Mancuso D.J., Sims H.F., Muslin A.J., Gross R.W. Biochemistry 42:11798-11807(2003) [PubMed] [Europe PMC] [Abstract] Cited for: ISOPRENYLATION AT CYS-538, METHYLATION AT CYS-538.
[12]	"Phosphoproteome of resting human platelets." Zahedi R.P., Lewandrowski U., Wiesner J., Wortelkamp S., Moebius J., Schuetz C., Walter U., Gambaryan S., Sickmann A. J. Proteome Res. 7:526-534(2008) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. Tissue: Platelet.
+	Additional computationally mapped references.

Web resources

NIEHS-SNPs

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF058921 mRNA. Translation: AAC32823.1. AF065214 mRNA. Translation: AAC78835.1. AY485310 Genomic DNA. Translation: AAR25453.1. AK295400 mRNA. Translation: BAG58352.1. AK314524 mRNA. Translation: BAG37118.1. CR456816 mRNA. Translation: CAG33097.1. AC010458 Genomic DNA. No translation available. AC011466 Genomic DNA. No translation available. CH471177 Genomic DNA. Translation: EAW52314.1. BC063416 mRNA. Translation: AAH63416.1. AB105807 Genomic DNA. Translation: BAC87745.1. AL050193 mRNA. Translation: CAB43312.3.
IPI	IPI00910091. IPI00929100.
PIR	T13162.
RefSeq	NP_001152794.1. NM_001159322.1. NP_001152795.1. NM_001159323.1. NP_003697.2. NM_003706.2.
UniGene	Hs.631562.
3D structure databases
ProteinModelPortal	Q9UP65.
ModBase	Search...
Protein-protein interaction databases
STRING	9606.ENSP00000346228.
PTM databases
PhosphoSite	Q9UP65.
Polymorphism databases
DMDM	47117337.
Proteomic databases
PaxDb	Q9UP65.
PRIDE	Q9UP65.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000354276; ENSP00000346228; ENSG00000105499. ENST00000413144; ENSP00000400036; ENSG00000105499. ENST00000599111; ENSP00000472546; ENSG00000105499. ENST00000599921; ENSP00000469473; ENSG00000105499.
GeneID	8605.
KEGG	hsa:8605.
UCSC	uc002phw.3. human.
Organism-specific databases
CTD	8605.
GeneCards	GC19M048551.
HGNC	HGNC:9037. PLA2G4C.
HPA	HPA043083.
MIM	603602. gene.
neXtProt	NX_Q9UP65.
PharmGKB	PA33365.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG278787.
HOVERGEN	HBG058910.
InParanoid	Q9UP65.
KO	K16342.
OMA	HEDPERK.
OrthoDB	EOG43FGWN.
PhylomeDB	Q9UP65.
Enzyme and pathway databases
Reactome	REACT_111217. Metabolism.
Gene expression databases
ArrayExpress	Q9UP65.
Bgee	Q9UP65.
CleanEx	HS_PLA2G4C.
Genevestigator	Q9UP65.
GermOnline	ENSG00000105499. Homo sapiens.
Family and domain databases
InterPro	IPR016035. Acyl_Trfase/lysoPLipase. IPR002642. LysoPLipase_cat_dom. [Graphical view]
Pfam	PF01735. PLA2_B. 1 hit. [Graphical view]
SMART	SM00022. PLAc. 1 hit. [Graphical view]
SUPFAM	SSF52151. Acyl_Trfase/lysoPlipase. 1 hit.
PROSITE	PS51210. PLA2C. 1 hit. [Graphical view]
ProtoNet	Search...
Other
BindingDB	Q9UP65.
ChEMBL	CHEMBL4834.
GenomeRNAi	8605.
NextBio	32245.
SOURCE	Search...

Entry information

Entry name

PA24C_HUMAN

Accession

Primary (citable) accession number: Q9UP65
Secondary accession number(s): B2RB71 , B4DI40, O75457, Q6IBI8, Q9UG68

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 10, 2004
Last sequence update:	February 8, 2011
Last modified:	May 1, 2013
This is version 96 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.