Q9UNU2 (Q9UNU2_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Complement protein C4B frameshift mutant EMBL AAC98380.1

Gene names

Name:

C4B EMBL AAC98380.1

Organism

Homo sapiens (Human) EMBL AAC98380.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	354 AA.
Sequence status	Fragment.
Protein existence	Predicted

Ontologies

Gene Ontology (GO)
Cellular_component	extracellular space Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAC98380.1

Sequences

	Sequence		Length	Mass (Da)
	Q9UNU2 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: DA3AAC7D85708237	FASTA	354	38,138
	10 20 30 40 50 60 HRGRTLDIPG NSDPNMIPDG DFNSYVRVTA SDPLDTLGSE GALSPGGVAS LLRLPRGCGE 70 80 90 100 110 120 QTMIYLAPTL AASRYLDKTE QWSTLPPETK DHAVDLIQKG YMRIQQFRKA DGSYAAWLSR 130 140 150 160 170 180 DSSTWLTAFV LKVLSLAQEQ VGGSPEKLQE TSNWLLSQQQ ADGSFQDLSP VIHRSMQGGL 190 200 210 220 230 240 VGNDETVALT AFVTIALHHG LAVFQDEGAE PLKQRVEASI SKASSFLGEK ASAGLLGAHA 250 260 270 280 290 300 AAITAYALTL TKAPADLRGV AHNNLMAMAQ ETGDNLYWGS QSLVLRAMPC RPPRLLATHP 310 320 330 340 350 TPCPRPQPCG LKPQPTPCCT SCFTRAKQRW QTRLRPGSPV RAASKGDSAV PKTR

References

[1]	"Genetic basis of human complement C4A deficiency. Detection of a point mutation leading to nonexpression." Barba G., Rittner C., Schneider P.M. J. Clin. Invest. 91:1681-1686(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Deficiency of Complement Protein C4 Due to Identical Frameshift Mutations in the C4A and C4B Genes." Lokki M.-L., Circolo A., Ahokas P., Rupert K.L., Yu C.Y., Colten H.R. Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF092085 Genomic DNA. Translation: AAC98380.1.
IPI	IPI00887154.
PIR	I55584.
UniGene	Hs.534847. Hs.720022.
3D structure databases
ProteinModelPortal	Q9UNU2.
ModBase	Search...
Proteomic databases
PRIDE	Q9UNU2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR011626. A2M_comp. IPR019742. MacrogloblnA2_CS. IPR019565. MacrogloblnA2_thiol-ester-bond. IPR008930. Terpenoid_cyclase/PrenylTrfase. [Graphical view]
Pfam	PF07678. A2M_comp. 1 hit. PF10569. Thiol-ester_cl. 1 hit. [Graphical view]
SUPFAM	SSF48239. Terp_cyc_toroid. 1 hit.
PROSITE	PS00477. ALPHA_2_MACROGLOBULIN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9UNU2_HUMAN

Accession

Primary (citable) accession number: Q9UNU2

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	May 29, 2013
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.