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Q9UNU2

- Q9UNU2_HUMAN

UniProt

Q9UNU2 - Q9UNU2_HUMAN

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Protein
Submitted name:

Complement protein C4B frameshift mutant

Gene
C4B
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Names & Taxonomyi

Protein namesi
Submitted name:
Complement protein C4B frameshift mutantImported
Gene namesi
Name:C4BImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. extracellular space Source: InterPro
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ9UNU2.

Structurei

3D structure databases

ProteinModelPortaliQ9UNU2.

Family & Domainsi

Family and domain databases

Gene3Di1.50.10.20. 1 hit.
InterProiIPR011626. A2M_comp.
IPR019742. MacrogloblnA2_CS.
IPR019565. MacrogloblnA2_thiol-ester-bond.
IPR008930. Terpenoid_cyclase/PrenylTrfase.
[Graphical view]
PfamiPF07678. A2M_comp. 1 hit.
PF10569. Thiol-ester_cl. 1 hit.
[Graphical view]
SUPFAMiSSF48239. SSF48239. 1 hit.
PROSITEiPS00477. ALPHA_2_MACROGLOBULIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9UNU2-1 [UniParc]FASTAAdd to Basket

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HRGRTLDIPG NSDPNMIPDG DFNSYVRVTA SDPLDTLGSE GALSPGGVAS    50
LLRLPRGCGE QTMIYLAPTL AASRYLDKTE QWSTLPPETK DHAVDLIQKG 100
YMRIQQFRKA DGSYAAWLSR DSSTWLTAFV LKVLSLAQEQ VGGSPEKLQE 150
TSNWLLSQQQ ADGSFQDLSP VIHRSMQGGL VGNDETVALT AFVTIALHHG 200
LAVFQDEGAE PLKQRVEASI SKASSFLGEK ASAGLLGAHA AAITAYALTL 250
TKAPADLRGV AHNNLMAMAQ ETGDNLYWGS QSLVLRAMPC RPPRLLATHP 300
TPCPRPQPCG LKPQPTPCCT SCFTRAKQRW QTRLRPGSPV RAASKGDSAV 350
PKTR 354
Length:354
Mass (Da):38,138
Last modified:May 1, 2000 - v1
Checksum:iDA3AAC7D85708237
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF092085 Genomic DNA. Translation: AAC98380.1.
PIRiI55584.
UniGeneiHs.534847.
Hs.720022.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF092085 Genomic DNA. Translation: AAC98380.1 .
PIRi I55584.
UniGenei Hs.534847.
Hs.720022.

3D structure databases

ProteinModelPortali Q9UNU2.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q9UNU2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 1.50.10.20. 1 hit.
InterProi IPR011626. A2M_comp.
IPR019742. MacrogloblnA2_CS.
IPR019565. MacrogloblnA2_thiol-ester-bond.
IPR008930. Terpenoid_cyclase/PrenylTrfase.
[Graphical view ]
Pfami PF07678. A2M_comp. 1 hit.
PF10569. Thiol-ester_cl. 1 hit.
[Graphical view ]
SUPFAMi SSF48239. SSF48239. 1 hit.
PROSITEi PS00477. ALPHA_2_MACROGLOBULIN. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genetic basis of human complement C4A deficiency. Detection of a point mutation leading to nonexpression."
    Barba G., Rittner C., Schneider P.M.
    J. Clin. Invest. 91:1681-1686(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Deficiency of Complement Protein C4 Due to Identical Frameshift Mutations in the C4A and C4B Genes."
    Lokki M.-L., Circolo A., Ahokas P., Rupert K.L., Yu C.Y., Colten H.R.
    Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ9UNU2_HUMAN
AccessioniPrimary (citable) accession number: Q9UNU2
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: April 16, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.