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Q9UNN5

- FAF1_HUMAN

UniProt

Q9UNN5 - FAF1_HUMAN

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Protein

FAS-associated factor 1

Gene

FAF1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

Potentiates but cannot initiate FAS-induced apoptosis.

GO - Molecular functioni

  1. heat shock protein binding Source: UniProtKB
  2. NF-kappaB binding Source: UniProtKB
  3. protein kinase binding Source: UniProtKB
  4. protein kinase regulator activity Source: UniProtKB
  5. ubiquitin binding Source: BHF-UCL
  6. ubiquitin protein ligase binding Source: BHF-UCL

GO - Biological processi

  1. apoptotic process Source: UniProtKB-KW
  2. cell death Source: UniProtKB
  3. cytoplasmic sequestering of NF-kappaB Source: UniProtKB
  4. positive regulation of apoptotic process Source: UniProtKB
  5. positive regulation of extrinsic apoptotic signaling pathway via death domain receptors Source: Ensembl
  6. positive regulation of protein complex assembly Source: UniProtKB
  7. proteasome-mediated ubiquitin-dependent protein catabolic process Source: UniProtKB
  8. regulation of cell adhesion Source: Ensembl
  9. regulation of protein catabolic process Source: UniProtKB
  10. regulation of protein kinase activity Source: GOC
Complete GO annotation...

Keywords - Biological processi

Apoptosis

Enzyme and pathway databases

SignaLinkiQ9UNN5.

Names & Taxonomyi

Protein namesi
Recommended name:
FAS-associated factor 1
Short name:
hFAF1
Alternative name(s):
UBX domain-containing protein 12
UBX domain-containing protein 3A
Gene namesi
Name:FAF1
Synonyms:UBXD12, UBXN3A
ORF Names:CGI-03
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 1

Organism-specific databases

HGNCiHGNC:3578. FAF1.

Subcellular locationi

Nucleus Curated

GO - Cellular componenti

  1. CD95 death-inducing signaling complex Source: UniProtKB
  2. Cdc48p-Npl4p-Ufd1p AAA ATPase complex Source: BHF-UCL
  3. cytosol Source: UniProtKB
  4. nuclear envelope Source: Ensembl
  5. nucleus Source: UniProtKB
  6. perinuclear region of cytoplasm Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA27976.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 650650FAS-associated factor 1PRO_0000211038Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei320 – 3201Phosphoserine3 Publications

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ9UNN5.
PaxDbiQ9UNN5.
PRIDEiQ9UNN5.

PTM databases

PhosphoSiteiQ9UNN5.

Expressioni

Tissue specificityi

Most abundant in testis, slightly less abundant in skeletal muscle and heart, followed by prostate, thymus, ovary, small intestine, and colon. Not detected in the peripheral blood leukocytes.

Gene expression databases

BgeeiQ9UNN5.
CleanExiHS_FAF1.
ExpressionAtlasiQ9UNN5. baseline and differential.
GenevestigatoriQ9UNN5.

Organism-specific databases

HPAiHPA018253.
HPA019008.

Interactioni

Subunit structurei

Specifically interacts with the cytoplasmic domain of FAS. Interacts with NLRP12 DAPIN/PYRIN domain via its UBA domain.1 Publication

Protein-protein interaction databases

BioGridi116298. 97 interactions.
DIPiDIP-38245N.
IntActiQ9UNN5. 49 interactions.
MINTiMINT-88745.
STRINGi9606.ENSP00000379457.

Structurei

Secondary structure

1
650
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi7 – 1812Combined sources
Helixi23 – 3210Combined sources
Turni33 – 353Combined sources
Helixi37 – 415Combined sources
Beta strandi100 – 1067Combined sources
Beta strandi111 – 1177Combined sources
Helixi122 – 13312Combined sources
Turni137 – 1393Combined sources
Beta strandi146 – 1483Combined sources
Helixi156 – 1594Combined sources
Beta strandi163 – 1697Combined sources
Beta strandi172 – 1743Combined sources
Helixi330 – 34516Combined sources
Helixi357 – 3626Combined sources
Beta strandi365 – 3673Combined sources
Turni369 – 3713Combined sources
Beta strandi374 – 3807Combined sources
Helixi386 – 3938Combined sources
Turni394 – 3963Combined sources
Helixi398 – 4069Combined sources
Beta strandi408 – 4147Combined sources
Helixi418 – 43114Combined sources
Helixi434 – 4429Combined sources
Beta strandi449 – 4546Combined sources
Beta strandi463 – 4675Combined sources
Helixi473 – 49018Combined sources
Beta strandi573 – 5797Combined sources
Beta strandi585 – 5917Combined sources
Helixi596 – 60510Combined sources
Turni610 – 6123Combined sources
Beta strandi613 – 6164Combined sources
Beta strandi618 – 6203Combined sources
Helixi624 – 6263Combined sources
Turni633 – 6375Combined sources
Beta strandi640 – 6489Combined sources

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1H8CNMR-A569-650[»]
2DZMNMR-A99-191[»]
2EC4NMR-A325-495[»]
3E21X-ray1.73A5-47[»]
3QC8X-ray2.20B571-650[»]
3QCAX-ray2.90A/B/C/D571-650[»]
3QQ8X-ray2.00B568-650[»]
3QWZX-ray2.00B571-650[»]
3QX1X-ray1.60A/B571-650[»]
3R3MX-ray3.00A/B/C/D568-650[»]
ProteinModelPortaliQ9UNN5.
SMRiQ9UNN5. Positions 5-44, 99-191, 325-495, 570-649.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9UNN5.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 5757UBAAdd
BLAST
Domaini569 – 64678UBXPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 UBA domain.Curated
Contains 1 UBX domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiNOG288188.
GeneTreeiENSGT00530000063422.
HOGENOMiHOG000043073.
HOVERGENiHBG002876.
InParanoidiQ9UNN5.
OMAiWEGWPAS.
OrthoDBiEOG72NRPV.
PhylomeDBiQ9UNN5.
TreeFamiTF314172.

Family and domain databases

InterProiIPR012336. Thioredoxin-like_fold.
IPR006577. UAS.
IPR029071. Ubiquitin-rel_dom.
IPR001012. UBX_dom.
[Graphical view]
PfamiPF00789. UBX. 1 hit.
[Graphical view]
SMARTiSM00594. UAS. 1 hit.
SM00166. UBX. 1 hit.
[Graphical view]
SUPFAMiSSF52833. SSF52833. 1 hit.
SSF54236. SSF54236. 3 hits.
PROSITEiPS50033. UBX. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform Long (identifier: Q9UNN5-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MASNMDREMI LADFQACTGI ENIDEAITLL EQNNWDLVAA INGVIPQENG
60 70 80 90 100
ILQSEYGGET IPGPAFNPAS HPASAPTSSS SSAFRPVMPS RQIVERQPRM
110 120 130 140 150
LDFRVEYRDR NVDVVLEDTC TVGEIKQILE NELQIPVSKM LLKGWKTGDV
160 170 180 190 200
EDSTVLKSLH LPKNNSLYVL TPDLPPPSSS SHAGALQESL NQNFMLIITH
210 220 230 240 250
REVQREYNLN FSGSSTIQEV KRNVYDLTSI PVRHQLWEGW PTSATDDSMC
260 270 280 290 300
LAESGLSYPC HRLTVGRRSS PAQTREQSEE QITDVHMVSD SDGDDFEDAT
310 320 330 340 350
EFGVDDGEVF GMASSALRKS PMMPENAENE GDALLQFTAE FSSRYGDCHP
360 370 380 390 400
VFFIGSLEAA FQEAFYVKAR DRKLLAIYLH HDESVLTNVF CSQMLCAESI
410 420 430 440 450
VSYLSQNFIT WAWDLTKDSN RARFLTMCNR HFGSVVAQTI RTQKTDQFPL
460 470 480 490 500
FLIIMGKRSS NEVLNVIQGN TTVDELMMRL MAAMEIFTAQ QQEDIKDEDE
510 520 530 540 550
REARENVKRE QDEAYRLSLE ADRAKREAHE REMAEQFRLE QIRKEQEEER
560 570 580 590 600
EAIRLSLEQA LPPEPKEENA EPVSKLRIRT PSGEFLERRF LASNKLQIVF
610 620 630 640 650
DFVASKGFPW DEYKLLSTFP RRDVTQLDPN KSLLEVKLFP QETLFLEAKE
Length:650
Mass (Da):73,954
Last modified:May 2, 2002 - v2
Checksum:i7FB9018B9A230488
GO
Isoform Short (identifier: Q9UNN5-2) [UniParc]FASTAAdd to Basket

Also known as: hFAF1(s)

The sequence of this isoform differs from the canonical sequence as follows:
     188-339: Missing.

Note: No experimental confirmation available.

Show »
Length:498
Mass (Da):56,934
Checksum:iA9B444F8E8257017
GO

Sequence cautioni

The sequence AAD51876.1 differs from that shown. Reason: Erroneous initiation.

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti448 – 4481F → K in AAD51886. (PubMed:10462485)Curated
Sequence conflicti448 – 4481F → K in AAD51876. (PubMed:10462485)Curated
Sequence conflicti498 – 4981E → G in AAD51886. (PubMed:10462485)Curated
Sequence conflicti498 – 4981E → G in AAD51876. (PubMed:10462485)Curated
Sequence conflicti529 – 5291H → R in AAD51886. (PubMed:10462485)Curated
Sequence conflicti529 – 5291H → R in AAD51876. (PubMed:10462485)Curated

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei188 – 339152Missing in isoform Short. 1 PublicationVSP_006704Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF106798 mRNA. Translation: AAD51886.1.
AF094700 mRNA. Translation: AAD51876.1. Different initiation.
AF136173 mRNA. Translation: AAP97263.1.
AJ271408 mRNA. Translation: CAB67705.1.
AF132938 mRNA. Translation: AAD27713.1.
AL359977
, AC091610, AC118557, AL049637, AL603746 Genomic DNA. Translation: CAH70189.1.
AL603746
, AC091610, AC118557, AL049637, AL359977 Genomic DNA. Translation: CAH72113.1.
CH471059 Genomic DNA. Translation: EAX06837.1.
BC004970 mRNA. Translation: AAH04970.1.
BC067100 mRNA. Translation: AAH67100.1.
AL133631 mRNA. Translation: CAB63755.1.
CCDSiCCDS554.1. [Q9UNN5-1]
PIRiJC7093.
T43466.
RefSeqiNP_008982.1. NM_007051.2. [Q9UNN5-1]
UniGeneiHs.530402.

Genome annotation databases

EnsembliENST00000396153; ENSP00000379457; ENSG00000185104. [Q9UNN5-1]
GeneIDi11124.
KEGGihsa:11124.
UCSCiuc001cse.1. human. [Q9UNN5-1]

Polymorphism databases

DMDMi20454906.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF106798 mRNA. Translation: AAD51886.1 .
AF094700 mRNA. Translation: AAD51876.1 . Different initiation.
AF136173 mRNA. Translation: AAP97263.1 .
AJ271408 mRNA. Translation: CAB67705.1 .
AF132938 mRNA. Translation: AAD27713.1 .
AL359977
, AC091610 , AC118557 , AL049637 , AL603746 Genomic DNA. Translation: CAH70189.1 .
AL603746
, AC091610 , AC118557 , AL049637 , AL359977 Genomic DNA. Translation: CAH72113.1 .
CH471059 Genomic DNA. Translation: EAX06837.1 .
BC004970 mRNA. Translation: AAH04970.1 .
BC067100 mRNA. Translation: AAH67100.1 .
AL133631 mRNA. Translation: CAB63755.1 .
CCDSi CCDS554.1. [Q9UNN5-1 ]
PIRi JC7093.
T43466.
RefSeqi NP_008982.1. NM_007051.2. [Q9UNN5-1 ]
UniGenei Hs.530402.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1H8C NMR - A 569-650 [» ]
2DZM NMR - A 99-191 [» ]
2EC4 NMR - A 325-495 [» ]
3E21 X-ray 1.73 A 5-47 [» ]
3QC8 X-ray 2.20 B 571-650 [» ]
3QCA X-ray 2.90 A/B/C/D 571-650 [» ]
3QQ8 X-ray 2.00 B 568-650 [» ]
3QWZ X-ray 2.00 B 571-650 [» ]
3QX1 X-ray 1.60 A/B 571-650 [» ]
3R3M X-ray 3.00 A/B/C/D 568-650 [» ]
ProteinModelPortali Q9UNN5.
SMRi Q9UNN5. Positions 5-44, 99-191, 325-495, 570-649.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 116298. 97 interactions.
DIPi DIP-38245N.
IntActi Q9UNN5. 49 interactions.
MINTi MINT-88745.
STRINGi 9606.ENSP00000379457.

PTM databases

PhosphoSitei Q9UNN5.

Polymorphism databases

DMDMi 20454906.

Proteomic databases

MaxQBi Q9UNN5.
PaxDbi Q9UNN5.
PRIDEi Q9UNN5.

Protocols and materials databases

DNASUi 11124.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000396153 ; ENSP00000379457 ; ENSG00000185104 . [Q9UNN5-1 ]
GeneIDi 11124.
KEGGi hsa:11124.
UCSCi uc001cse.1. human. [Q9UNN5-1 ]

Organism-specific databases

CTDi 11124.
GeneCardsi GC01M050905.
HGNCi HGNC:3578. FAF1.
HPAi HPA018253.
HPA019008.
MIMi 604460. gene.
neXtProti NX_Q9UNN5.
PharmGKBi PA27976.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG288188.
GeneTreei ENSGT00530000063422.
HOGENOMi HOG000043073.
HOVERGENi HBG002876.
InParanoidi Q9UNN5.
OMAi WEGWPAS.
OrthoDBi EOG72NRPV.
PhylomeDBi Q9UNN5.
TreeFami TF314172.

Enzyme and pathway databases

SignaLinki Q9UNN5.

Miscellaneous databases

ChiTaRSi FAF1. human.
EvolutionaryTracei Q9UNN5.
GeneWikii FAF1.
GenomeRNAii 11124.
NextBioi 42280.
PROi Q9UNN5.
SOURCEi Search...

Gene expression databases

Bgeei Q9UNN5.
CleanExi HS_FAF1.
ExpressionAtlasi Q9UNN5. baseline and differential.
Genevestigatori Q9UNN5.

Family and domain databases

InterProi IPR012336. Thioredoxin-like_fold.
IPR006577. UAS.
IPR029071. Ubiquitin-rel_dom.
IPR001012. UBX_dom.
[Graphical view ]
Pfami PF00789. UBX. 1 hit.
[Graphical view ]
SMARTi SM00594. UAS. 1 hit.
SM00166. UBX. 1 hit.
[Graphical view ]
SUPFAMi SSF52833. SSF52833. 1 hit.
SSF54236. SSF54236. 3 hits.
PROSITEi PS50033. UBX. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Identification and characterization of human Fas associated factor 1, hFAF1."
    Ryu S.-W., Chae S.-K., Lee K.-J., Kim E.
    Biochem. Biophys. Res. Commun. 262:388-394(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS LONG AND SHORT), CHARACTERIZATION.
    Tissue: Brain and Liver.
  2. "Cloning of a new human cDNA homologous to Mus musculus FAF1."
    Ding J.B., Yu L., Zhao S.Y.
    Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM LONG).
  3. "Full length cDNA sequence and chromosomal localization of the human Fas-associated factor 1 gene, hFaf1."
    Boldyreff B.
    Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM LONG).
  4. "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics."
    Lai C.-H., Chou C.-Y., Ch'ang L.-Y., Liu C.-S., Lin W.-C.
    Genome Res. 10:703-713(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM LONG).
  5. "The DNA sequence and biological annotation of human chromosome 1."
    Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
    , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
    Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM LONG).
    Tissue: Brain and Kidney.
  8. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 97-650 (ISOFORM LONG).
    Tissue: Testis.
  9. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-320, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  10. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-320, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  11. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-320, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  12. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  13. "The NLRP12 pyrin domain: structure, dynamics, and functional insights."
    Pinheiro A.S., Eibl C., Ekman-Vural Z., Schwarzenbacher R., Peti W.
    J. Mol. Biol. 413:790-803(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH NLRP12.
  14. "The UBX domain: a widespread ubiquitin-like module."
    Buchberger A., Howard M.J., Proctor M., Bycroft M.M.
    J. Mol. Biol. 307:17-24(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: STRUCTURE BY NMR OF 569-650.
  15. "Solution structure of the ubiquitin-like domain in human FAS-associated factor 1 (hFAF1)."
    RIKEN structural genomics initiative (RSGI)
    Submitted (OCT-2007) to the PDB data bank
    Cited for: STRUCTURE BY NMR OF 99-191.
  16. "Structure and interaction of ubiquitin-associated domain of human Fas-associated factor 1."
    Song J., Park J.K., Lee J.J., Choi Y.S., Ryu K.S., Kim J.H., Kim E., Lee K.J., Jeon Y.H., Kim E.E.
    Protein Sci. 18:2265-2276(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.73 ANGSTROMS) OF 5-47, DOMAIN UBA.

Entry informationi

Entry nameiFAF1_HUMAN
AccessioniPrimary (citable) accession number: Q9UNN5
Secondary accession number(s): Q549F0
, Q9UF34, Q9UNT3, Q9Y2Z3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 2, 2002
Last sequence update: May 2, 2002
Last modified: October 29, 2014
This is version 137 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3