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Protein
Submitted name:

C-C chemokine receptor 5

Gene

CCR5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
C-C chemokine receptor 5Imported
Gene namesi
Name:CCR5Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei29 – 49HelicalSequence analysisAdd BLAST21
Transmembranei61 – 80HelicalSequence analysisAdd BLAST20
Transmembranei100 – 122HelicalSequence analysisAdd BLAST23
Transmembranei134 – 159HelicalSequence analysisAdd BLAST26
Transmembranei191 – 214HelicalSequence analysisAdd BLAST24
Transmembranei226 – 244HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PeptideAtlasiQ9UN28
PRIDEiQ9UN28

Structurei

3D structure databases

ProteinModelPortaliQ9UN28
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini40 – 290G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST251

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3656 Eukaryota
ENOG410XRW9 LUCA
HOVERGENiHBG106917

Family and domain databases

InterProiView protein in InterPro
IPR002240 Chemokine_CCR5
IPR000355 Chemokine_rcpt
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00657 CCCHEMOKINER
PR01110 CHEMOKINER5
PR00237 GPCRRHODOPSN
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Fragment.

Q9UN28-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
PIYDINYYTS EPCQKINVKQ IAARLLPPLY SLVFIFGFVG NMLVILILIN
60 70 80 90 100
CKRLKSMTDI YLLNLAISDL FFLLTVPFWA HYAAAQWDFG NTMCQLLTGL
110 120 130 140 150
YFIGFFSGIF FIILLTIDRY LAVVHAVFAL KARTVTFGVV TSVITWVVAV
160 170 180 190 200
FASLPGIIFT RSQKEGLHYT CSSHFPYSQY QFWKNFQTLK IVILGLVLPL
210 220 230 240 250
LVMVICYSGI LKTLLRCRNE KKRHRAVRLI FTIMIVYFLF WAPYNIVLLL
260 270 280 290 300
NTFQEFFGLN NCRSSNRLDQ AMQVTETLGM THCCINPIIY AFVGEKFRNY
310 320 330
LLVFFQKHIA KRFCKCCSIF QQEAPERASS VYTRSTGEQ
Length:339
Mass (Da):39,184
Last modified:May 1, 2000 - v1
Checksum:i56C819F92D6DB1A6
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei339Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF161913 Genomic DNA Translation: AAD47670.1
UniGeneiHs.450802

Similar proteinsi

Entry informationi

Entry nameiQ9UN28_HUMAN
AccessioniPrimary (citable) accession number: Q9UN28
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: May 23, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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