ID   Q9UMZ1_HUMAN            Unreviewed;       101 AA.
AC   Q9UMZ1;
DT   01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2000, sequence version 1.
DT   27-MAR-2024, entry version 61.
DE   RecName: Full=Prothymosin alpha {ECO:0000256|ARBA:ARBA00040447};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:AAD50987.1};
RN   [1] {ECO:0000313|EMBL:AAD50987.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Guo B.Y., Zhang S.Y., Yu J.G., Dao S.Y., Bian G.X., Tan Y.X., Miao H.,
RA   Qiu L.;
RL   Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Prothymosin alpha may mediate immune function by conferring
CC       resistance to certain opportunistic infections.
CC       {ECO:0000256|ARBA:ARBA00037621}.
CC   -!- SUBUNIT: Interacts with NUPR1; regulates apoptotic process.
CC       {ECO:0000256|ARBA:ARBA00038744}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the pro/parathymosin family.
CC       {ECO:0000256|ARBA:ARBA00008032}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF170294; AAD50987.1; -; mRNA.
DR   AlphaFoldDB; Q9UMZ1; -.
DR   GO; GO:0044183; F:protein folding chaperone; EXP:DisProt.
DR   DisProt; DP01228; -.
DR   InterPro; IPR004931; Pro/parathymosin.
DR   PANTHER; PTHR22745; PROTHYMOSIN ALPHA; 1.
DR   PANTHER; PTHR22745:SF0; PROTHYMOSIN ALPHA; 1.
DR   Pfam; PF03247; Prothymosin; 1.
PE   2: Evidence at transcript level;
FT   REGION          1..101
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        12..37
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        38..72
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        73..101
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   101 AA;  11058 MW;  ACA2FAE019A91711 CRC64;
     MSDAAVDTSS EITTEDLKEK KEVVEEAENG RDAPADEENG EQEADNEVDE EQEEGGEEEG
     DGEEEDGDED EGAESATDKR AAEDDEDNDV DTKKQKTDED D
//