Q9UML7 (Q9UML7_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Cystic fibrosis transmembrane conductance regulator EMBL AAC41928.1

Gene names

Name:

CFTR EMBL AAC41928.1

Organism

Homo sapiens (Human) EMBL AAC41928.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	27 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane EMBL AAC41928.1
Gene Ontology (GO)
Biological_process	bicarbonate transport Inferred from electronic annotation. Source: Compara cellular response to hormone stimulus Inferred from electronic annotation. Source: Compara cholesterol biosynthetic process Inferred from electronic annotation. Source: Compara cholesterol transport Inferred from electronic annotation. Source: Compara iodide transport Inferred from electronic annotation. Source: Compara lung development Inferred from electronic annotation. Source: Compara positive regulation of vasodilation Inferred from electronic annotation. Source: Compara response to cytokine stimulus Inferred from electronic annotation. Source: Compara response to drug Inferred from electronic annotation. Source: Compara response to estrogen stimulus Inferred from electronic annotation. Source: Compara response to peptide hormone stimulus Inferred from electronic annotation. Source: Compara transepithelial chloride transport Inferred from electronic annotation. Source: Compara vasodilation Inferred from electronic annotation. Source: Compara water transport Inferred from electronic annotation. Source: Compara
Cellular_component	apical plasma membrane Inferred from electronic annotation. Source: Compara basolateral plasma membrane Inferred from electronic annotation. Source: Compara cytoplasmic vesicle membrane Inferred from electronic annotation. Source: Compara integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW microvillus Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAC41928.1
	Non-terminal residue	27	1	EMBL AAC41928.1

Sequences

	Sequence		Length	Mass (Da)
	Q9UML7 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: B67FFD4448115C9B	FASTA	27	3,167
	10 20 LLHPAIFGLH HIGMQMRIAM FSLIYKK

References

[1]	"Recurrent nasal polyps as a monosymptomatic form of cystic fibrosis associated with a novel in-frame deletion (591del18) in the CFTR gene." Varon R., Magdorf K., Staab D., Wahn H.U., Krawczak M., Sperling K., Reis A. Hum. Mol. Genet. 4:1463-1464(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L49339 Genomic DNA. Translation: AAC41928.1.
IPI	IPI00816790.
UniGene	Hs.489786. Hs.621460. Hs.661104.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Gene expression databases
ArrayExpress	Q9UML7.
Bgee	Q9UML7.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

Q9UML7_HUMAN

Accession

Primary (citable) accession number: Q9UML7

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	May 29, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.