Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Cystic fibrosis transmembrane conductance regulator

Gene

CFTR

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Cystic fibrosis transmembrane conductance regulatorImported
Gene namesi
Name:CFTRImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiQ9UML7.

Family & Domainsi

Keywords - Domaini

TransmembraneImported

Family and domain databases

InterProiIPR009147. CFTR/ABCC7.
[Graphical view]
PANTHERiPTHR24223:SF19. PTHR24223:SF19. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q9UML7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20 
LLHPAIFGLH HIGMQMRIAM FSLIYKK
Length:27
Mass (Da):3,167
Last modified:May 1, 2000 - v1
Checksum:iB67FFD4448115C9B
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei27 – 271Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L49339 Genomic DNA. Translation: AAC41928.1.
UniGeneiHs.489786.
Hs.621460.
Hs.661104.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L49339 Genomic DNA. Translation: AAC41928.1.
UniGeneiHs.489786.
Hs.621460.
Hs.661104.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Gene expression databases

BgeeiQ9UML7.

Family and domain databases

InterProiIPR009147. CFTR/ABCC7.
[Graphical view]
PANTHERiPTHR24223:SF19. PTHR24223:SF19. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Recurrent nasal polyps as a monosymptomatic form of cystic fibrosis associated with a novel in-frame deletion (591del18) in the CFTR gene."
    Varon R., Magdorf K., Staab D., Wahn H.U., Krawczak M., Sperling K., Reis A.
    Hum. Mol. Genet. 4:1463-1464(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ9UML7_HUMAN
AccessioniPrimary (citable) accession number: Q9UML7
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: May 27, 2015
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.