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Q9UMB2

- Q9UMB2_HUMAN

UniProt

Q9UMB2 - Q9UMB2_HUMAN

Protein
Submitted name:

Protein phosphatase from PCR H32 protein

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 3 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. calmodulin-dependent protein phosphatase activity Source: Ensembl

    GO - Biological processi

    1. calcineurin-NFAT signaling cascade Source: Ensembl
    2. calcium ion-dependent exocytosis Source: Ensembl
    3. calcium ion transport Source: Ensembl
    4. cellular response to glucose stimulus Source: Ensembl
    5. G1/S transition of mitotic cell cycle Source: Ensembl
    6. heart development Source: Ensembl
    7. multicellular organismal response to stress Source: Ensembl
    8. negative regulation of insulin secretion Source: Ensembl
    9. negative regulation of T cell mediated cytotoxicity Source: Ensembl
    10. positive regulation of insulin secretion involved in cellular response to glucose stimulus Source: Ensembl
    11. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
    12. protein dephosphorylation Source: Ensembl
    13. protein import into nucleus Source: Ensembl
    14. protein phosphorylation Source: Ensembl
    15. regulation of excitatory postsynaptic membrane potential Source: Ensembl
    16. regulation of synaptic transmission Source: Ensembl
    17. response to amphetamine Source: Ensembl
    18. response to cytokine Source: Ensembl
    19. skeletal muscle fiber development Source: Ensembl
    20. T cell differentiation Source: Ensembl
    21. T cell homeostasis Source: Ensembl
    22. transition between fast and slow fiber Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein phosphatase from PCR H32 proteinImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. calcineurin complex Source: Ensembl
    2. cytosol Source: Ensembl
    3. mitochondrion Source: Ensembl
    4. nucleus Source: Ensembl
    5. plasma membrane Source: Ensembl
    6. Z disc Source: Ensembl

    PTM / Processingi

    Proteomic databases

    PRIDEiQ9UMB2.

    Expressioni

    Gene expression databases

    ArrayExpressiQ9UMB2.
    BgeeiQ9UMB2.

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000172699.

    Family and domain databases

    Gene3Di3.60.21.10. 1 hit.
    InterProiIPR029052. Metallo-depent_PP-like.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q9UMB2-1 [UniParc]FASTAAdd to Basket

    « Hide

    QFFDLMKLFE VGGSPANTRY LFLG                               24
    Length:24
    Mass (Da):2,751
    Last modified:May 1, 2000 - v1
    Checksum:i15462B91DC1E7FAE
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei24 – 241Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    S40012 Genomic DNA. Translation: AAB22473.1.
    UniGeneiHs.500067.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    S40012 Genomic DNA. Translation: AAB22473.1 .
    UniGenei Hs.500067.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q9UMB2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOGENOMi HOG000172699.

    Gene expression databases

    ArrayExpressi Q9UMB2.
    Bgeei Q9UMB2.

    Family and domain databases

    Gene3Di 3.60.21.10. 1 hit.
    InterProi IPR029052. Metallo-depent_PP-like.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Polymerase chain reactions using Saccharomyces, Drosophila and human DNA predict a large family of protein serine/threonine phosphatases."
      Chen M.X., Chen Y.H., Cohen P.T.
      FEBS Lett. 306:54-58(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ9UMB2_HUMAN
    AccessioniPrimary (citable) accession number: Q9UMB2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 1, 2000
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 74 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.