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Q9UMA6

- Q9UMA6_HUMAN

UniProt

Q9UMA6 - Q9UMA6_HUMAN

Protein
Submitted name:

Type I collagen alpha 1 chain

Gene

COL1A1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 3 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. extracellular matrix structural constituent Source: Ensembl

    GO - Biological processi

    1. blood vessel development Source: Ensembl
    2. bone trabecula formation Source: Ensembl
    3. cartilage development involved in endochondral bone morphogenesis Source: Ensembl
    4. cellular response to amino acid stimulus Source: Ensembl
    5. cellular response to mechanical stimulus Source: Ensembl
    6. cellular response to retinoic acid Source: Ensembl
    7. cellular response to transforming growth factor beta stimulus Source: Ensembl
    8. endochondral ossification Source: Ensembl
    9. face morphogenesis Source: Ensembl
    10. intramembranous ossification Source: Ensembl
    11. negative regulation of cell-substrate adhesion Source: Ensembl
    12. osteoblast differentiation Source: Ensembl
    13. protein heterotrimerization Source: Ensembl
    14. protein transport Source: Ensembl
    15. response to cAMP Source: Ensembl
    16. response to corticosteroid Source: Ensembl
    17. response to estradiol Source: Ensembl
    18. response to hydrogen peroxide Source: Ensembl
    19. response to nutrient Source: Ensembl
    20. response to peptide hormone Source: Ensembl
    21. skin development Source: Ensembl
    22. wound healing Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Type I collagen alpha 1 chainImported
    Gene namesi
    Name:COL1A1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. collagen type I trimer Source: Ensembl
    2. cytoplasm Source: Ensembl
    3. extracellular space Source: Ensembl

    PTM / Processingi

    Proteomic databases

    PRIDEiQ9UMA6.

    Expressioni

    Gene expression databases

    ArrayExpressiQ9UMA6.
    BgeeiQ9UMA6.

    Family & Domainsi

    Keywords - Domaini

    CollagenImported

    Sequencei

    Sequence statusi: Fragment.

    Q9UMA6-1 [UniParc]FASTAAdd to Basket

    « Hide

    GEAGPQGPRG SEGPQGVRGE PGPPGPA                            27
    Length:27
    Mass (Da):2,496
    Last modified:May 1, 2000 - v1
    Checksum:iE9BCD23967CEABCD
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei27 – 271Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    S58915 Genomic DNA. Translation: AAB26324.1.
    UniGeneiHs.172928.
    Hs.681002.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    S58915 Genomic DNA. Translation: AAB26324.1 .
    UniGenei Hs.172928.
    Hs.681002.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q9UMA6.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    ChiTaRSi COL1A1. human.

    Gene expression databases

    ArrayExpressi Q9UMA6.
    Bgeei Q9UMA6.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Homology-mediated recombination between type I collagen gene exons results in an internal tandem duplication and lethal osteogenesis imperfecta."
      Cohn D.H., Zhang X., Byers P.H.
      Hum. Mutat. 2:21-27(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ9UMA6_HUMAN
    AccessioniPrimary (citable) accession number: Q9UMA6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 1, 2000
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 52 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.