APC protein - Homo sapiens (Human)

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Unreviewed, UniProtKB/TrEMBL Q9UM98 (Q9UM98_HUMAN)

Last modified January 19, 2010. Version 29. History...

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Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information

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Names and origin

Protein names

Submitted name:
APC protein EMBL AAD13998.1

Gene names

Name:

APC EMBL AAD13998.1

Organism

Homo sapiens (Human) EMBL AAD13998.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

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Protein attributes

Sequence length	29 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level.

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Ontologies

Gene Ontology (GO)
Biological process	T cell differentiation in the thymus Inferred from electronic annotation. Source: Compara Wnt receptor signaling pathway through beta-catenin Inferred from electronic annotation. Source: Compara anterior/posterior pattern formation Inferred from electronic annotation. Source: Compara axis specification Inferred from electronic annotation. Source: Compara axonogenesis Inferred from electronic annotation. Source: Compara cell migration Inferred from electronic annotation. Source: Compara chromosome organization Inferred from electronic annotation. Source: Compara cytokinesis after mitosis Inferred from electronic annotation. Source: Compara dorsal/ventral pattern formation Inferred from electronic annotation. Source: Compara establishment or maintenance of cell polarity Inferred from electronic annotation. Source: Compara hair follicle development Inferred from electronic annotation. Source: Compara kidney development Inferred from electronic annotation. Source: Compara mitotic metaphase/anaphase transition Inferred from electronic annotation. Source: Compara muscle homeostasis Inferred from electronic annotation. Source: Compara negative regulation of MAPKKK cascade Inferred from electronic annotation. Source: Compara negative regulation of Wnt receptor signaling pathway Inferred from electronic annotation. Source: Compara negative regulation of apoptosis Inferred from electronic annotation. Source: Compara negative regulation of epithelial cell proliferation Inferred from electronic annotation. Source: Compara negative regulation of microtubule depolymerization Inferred from electronic annotation. Source: Compara negative regulation of odontogenesis Inferred from electronic annotation. Source: Compara positive regulation of apoptosis Inferred from electronic annotation. Source: Compara positive regulation of cell adhesion Inferred from electronic annotation. Source: Compara positive regulation of cell division Inferred from electronic annotation. Source: Compara positive regulation of cell migration Inferred from electronic annotation. Source: Compara positive regulation of epithelial cell differentiation Inferred from electronic annotation. Source: Compara positive regulation of microtubule polymerization Inferred from electronic annotation. Source: Compara positive regulation of protein catabolic process Inferred from electronic annotation. Source: Compara proximal/distal pattern formation Inferred from electronic annotation. Source: Compara regulation of attachment of spindle microtubules to kinetochore Inferred from electronic annotation. Source: Compara regulation of cell cycle Inferred from electronic annotation. Source: Compara regulation of nitrogen compound metabolic process Inferred from electronic annotation. Source: Compara regulation of osteoblast differentiation Inferred from electronic annotation. Source: Compara regulation of osteoclast differentiation Inferred from electronic annotation. Source: Compara response to drug Inferred from electronic annotation. Source: Compara retina development in camera-type eye Inferred from electronic annotation. Source: Compara skin development Inferred from electronic annotation. Source: Compara somatic stem cell maintenance Inferred from electronic annotation. Source: Compara thymus development Inferred from electronic annotation. Source: Compara
Cellular component	axon part Inferred from electronic annotation. Source: Compara cell projection membrane Inferred from electronic annotation. Source: Compara cytoplasm Inferred from electronic annotation. Source: Compara cytoplasmic microtubule Inferred from electronic annotation. Source: Compara growth cone Inferred from electronic annotation. Source: Compara nucleus Inferred from electronic annotation. Source: Compara
Molecular function	beta-catenin binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

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Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Experimental info

Non-terminal residue

EMBL AAD13998.1

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Sequences

Sequence

Length

Mass (Da)

Tools

Q9UM98-1 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: D03642ACDC23F3A3
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FASTA

3,581

        10         20 
RSLLLADLDK EEKEKDWYYA QLQNLTKRI

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References

[1]	"Alleles of the APC gene: an attenuated form of familial polyposis." Spirio L., Olschwang S., Groden J., Robertson M., Samowitz W., Joslyn G., Gelbert L., Thliveris A., Carlson M., Otterud B. Cell 75:951-957(1993) [PubMed: 8252630] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

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Cross-references

Sequence databases
EMBL GenBank DDBJ	S67788 mRNA. Translation: AAD13998.1.
IPI	IPI00012391.
UniGene	Hs.158932
3D structure databases
SMR	Q9UM98. Positions 1-29.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9UM98.
Genome annotation databases
Ensembl	ENST00000257430; ENSP00000257430; ENSG00000134982; Homo sapiens. [Genome view] ENST00000395617; ENSP00000378979; ENSG00000134982; Homo sapiens. [Genome view] ENST00000457016; ENSP00000413133; ENSG00000134982; Homo sapiens. [Genome view]
Organism-specific databases
HGNC	HGNC:583. APC.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q9UM98.
Gene expression databases
ArrayExpress	Q9UM98.
Bgee	Q9UM98.
Family and domain databases
ProtoNet	Search...

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Entry information

Entry name

Q9UM98_HUMAN

Accession

Primary (citable) accession number: Q9UM98

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	January 19, 2010
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information

Names and origin

Protein attributes

Ontologies

Sequence annotation (Features)

Experimental info

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Entry information