Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9UM63

- PLAL1_HUMAN

UniProt

Q9UM63 - PLAL1_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Zinc finger protein PLAGL1

Gene

PLAGL1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

Shows weak transcriptional activatory activity. Transcriptional regulator of the type 1 receptor for pituitary adenylate cyclase-activating polypeptide.1 Publication

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri4 – 2623C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri32 – 5625C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri62 – 8423C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri91 – 11323C2H2-type 4PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri120 – 14223C2H2-type 5PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri156 – 17823C2H2-type 6PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri184 – 20724C2H2-type 7PROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  1. DNA binding Source: MGI
  2. metal ion binding Source: UniProtKB-KW
  3. RNA polymerase II regulatory region sequence-specific DNA binding Source: NTNU_SB
  4. RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Source: NTNU_SB
  5. sequence-specific DNA binding RNA polymerase II transcription factor activity Source: RefGenome

GO - Biological processi

  1. apoptotic process Source: ProtInc
  2. cell cycle arrest Source: ProtInc
  3. cell differentiation Source: RefGenome
  4. positive regulation of transcription from RNA polymerase II promoter Source: NTNU_SB
  5. skeletal muscle cell differentiation Source: Ensembl
  6. transcription from RNA polymerase II promoter Source: GOC
Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein PLAGL1
Alternative name(s):
Lost on transformation 1
Short name:
LOT-1
Pleiomorphic adenoma-like protein 1
Tumor suppressor ZAC
Gene namesi
Name:PLAGL1
Synonyms:LOT1, ZAC
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 6

Organism-specific databases

HGNCiHGNC:9046. PLAGL1.

Subcellular locationi

Nucleus 2 Publications

GO - Cellular componenti

  1. cytoplasm Source: HPA
  2. Golgi apparatus Source: HPA
  3. nucleus Source: HPA
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

Orphaneti96191. Paternal uniparental disomy of chromosome 6.
99886. Transient neonatal diabetes mellitus.
PharmGKBiPA33379.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 463463Zinc finger protein PLAGL1PRO_0000047222Add
BLAST

Proteomic databases

MaxQBiQ9UM63.
PaxDbiQ9UM63.
PRIDEiQ9UM63.

PTM databases

PhosphoSiteiQ9UM63.

Expressioni

Gene expression databases

BgeeiQ9UM63.
CleanExiHS_PLAGL1.
ExpressionAtlasiQ9UM63. baseline and differential.
GenevestigatoriQ9UM63.

Organism-specific databases

HPAiHPA055706.

Interactioni

Subunit structurei

Interacts with THRSP.1 Publication

Protein-protein interaction databases

BioGridi111341. 10 interactions.
IntActiQ9UM63. 1 interaction.
MINTiMINT-1188459.
STRINGi9606.ENSP00000346810.

Structurei

3D structure databases

ProteinModelPortaliQ9UM63.
SMRiQ9UM63. Positions 4-210.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 7 C2H2-type zinc fingers.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri4 – 2623C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri32 – 5625C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri62 – 8423C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri91 – 11323C2H2-type 4PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri120 – 14223C2H2-type 5PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri156 – 17823C2H2-type 6PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri184 – 20724C2H2-type 7PROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiCOG5048.
GeneTreeiENSGT00390000013640.
HOVERGENiHBG053608.
InParanoidiQ9UM63.
OMAiTCGVCAL.
OrthoDBiEOG71K62Q.
PhylomeDBiQ9UM63.
TreeFamiTF332024.

Family and domain databases

Gene3Di3.30.160.60. 5 hits.
InterProiIPR027775. C2H2_Znf_fam.
IPR027770. PLAGL1.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PANTHERiPTHR10032. PTHR10032. 1 hit.
PTHR10032:SF125. PTHR10032:SF125. 1 hit.
SMARTiSM00355. ZnF_C2H2. 7 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 7 hits.
PS50157. ZINC_FINGER_C2H2_2. 7 hits.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q9UM63-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MATFPCQLCG KTFLTLEKFT IHNYSHSRER PYKCVQPDCG KAFVSRYKLM
60 70 80 90 100
RHMATHSPQK SHQCAHCEKT FNRKDHLKNH LQTHDPNKMA FGCEECGKKY
110 120 130 140 150
NTMLGYKRHL ALHAASSGDL TCGVCALELG STEVLLDHLK AHAEEKPPSG
160 170 180 190 200
TKEKKHQCDH CERCFYTRKD VRRHLVVHTG CKDFLCQFCA QRFGRKDHLT
210 220 230 240 250
RHTKKTHSQE LMKESLQTGD LLSTFHTISP SFQLKAAALP PFPLGASAQN
260 270 280 290 300
GLASSLPAEV HSLTLSPPEQ AAQPMQPLPE SLASLHPSVS PGSPPPPLPN
310 320 330 340 350
HKYNTTSTSY SPLASLPLKA DTKGFCNISL FEDLPLQEPQ SPQKLNPGFD
360 370 380 390 400
LAKGNAGKVN LPKELPADAV NLTIPASLDL SPLLGFWQLP PPATQNTFGN
410 420 430 440 450
STLALGPGES LPHRLSCLGQ QQQEPPLAMG TVSLGQLPLP PIPHVFSAGT
460
GSAILPHFHH AFR
Length:463
Mass (Da):50,819
Last modified:September 11, 2007 - v2
Checksum:iB10C74DA409BD4F7
GO
Isoform 2 (identifier: Q9UM63-2) [UniParc]FASTAAdd to Basket

Also known as: ZACdelta2

The sequence of this isoform differs from the canonical sequence as follows:
     1-52: Missing.

Show »
Length:411
Mass (Da):44,668
Checksum:i735121F4BF16F7C8
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti81 – 811L → F in AAB67041. (PubMed:9150364)Curated
Sequence conflicti197 – 1971D → V in AAC34250. (PubMed:9722527)Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti272 – 2721A → V.
Corresponds to variant rs35263016 [ dbSNP | Ensembl ].
VAR_052729

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 5252Missing in isoform 2. 4 PublicationsVSP_028123Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U72621 mRNA. Translation: AAB67041.1.
U81992 mRNA. Translation: AAC34250.1.
AJ006354 mRNA. Translation: CAA06994.1.
AJ303119 mRNA. Translation: CAC39614.1.
AJ311395 mRNA. Translation: CAC39615.1.
AK314570 mRNA. Translation: BAG37151.1.
AK315184 mRNA. Translation: BAG37625.1.
BX537397 mRNA. Translation: CAD97639.1.
AL049844 Genomic DNA. Translation: CAI21447.1.
AL049844 Genomic DNA. Translation: CAB56564.1.
CH471051 Genomic DNA. Translation: EAW47852.1.
CH471051 Genomic DNA. Translation: EAW47853.1.
CH471051 Genomic DNA. Translation: EAW47854.1.
CH471051 Genomic DNA. Translation: EAW47855.1.
CH471051 Genomic DNA. Translation: EAW47856.1.
BC074814 mRNA. Translation: AAH74814.1.
BC109085 mRNA. Translation: AAI09086.1.
BC109086 mRNA. Translation: AAI09087.1.
CCDSiCCDS5202.1. [Q9UM63-1]
CCDS5203.1. [Q9UM63-2]
RefSeqiNP_001074420.1. NM_001080951.1. [Q9UM63-1]
NP_001074421.1. NM_001080952.1. [Q9UM63-1]
NP_001074422.1. NM_001080953.1. [Q9UM63-1]
NP_001074423.1. NM_001080954.1. [Q9UM63-1]
NP_001074424.1. NM_001080955.1. [Q9UM63-2]
NP_001074425.1. NM_001080956.1. [Q9UM63-2]
NP_001275966.1. NM_001289037.1. [Q9UM63-2]
NP_001275967.1. NM_001289038.1. [Q9UM63-2]
NP_001275968.1. NM_001289039.1. [Q9UM63-2]
NP_001275969.1. NM_001289040.1. [Q9UM63-2]
NP_001275970.1. NM_001289041.1. [Q9UM63-2]
NP_001275971.1. NM_001289042.1. [Q9UM63-1]
NP_001275972.1. NM_001289043.1. [Q9UM63-1]
NP_001275973.1. NM_001289044.1. [Q9UM63-1]
NP_001275974.1. NM_001289045.1. [Q9UM63-1]
NP_001275975.1. NM_001289046.1. [Q9UM63-1]
NP_001275976.1. NM_001289047.1. [Q9UM63-1]
NP_001275977.1. NM_001289048.1. [Q9UM63-1]
NP_001275978.1. NM_001289049.1. [Q9UM63-1]
NP_002647.2. NM_002656.3. [Q9UM63-2]
NP_006709.2. NM_006718.3. [Q9UM63-1]
UniGeneiHs.743225.

Genome annotation databases

EnsembliENST00000354765; ENSP00000346810; ENSG00000118495. [Q9UM63-1]
ENST00000360537; ENSP00000353734; ENSG00000118495. [Q9UM63-1]
ENST00000367571; ENSP00000356543; ENSG00000118495. [Q9UM63-1]
ENST00000367572; ENSP00000356544; ENSG00000118495. [Q9UM63-2]
ENST00000416623; ENSP00000400060; ENSG00000118495. [Q9UM63-1]
ENST00000417959; ENSP00000395960; ENSG00000118495. [Q9UM63-2]
ENST00000437412; ENSP00000392418; ENSG00000118495. [Q9UM63-2]
ENST00000444202; ENSP00000400929; ENSG00000118495. [Q9UM63-1]
GeneIDi5325.
KEGGihsa:5325.
UCSCiuc003qjv.3. human. [Q9UM63-1]

Polymorphism databases

DMDMi158523334.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Web resourcesi

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U72621 mRNA. Translation: AAB67041.1 .
U81992 mRNA. Translation: AAC34250.1 .
AJ006354 mRNA. Translation: CAA06994.1 .
AJ303119 mRNA. Translation: CAC39614.1 .
AJ311395 mRNA. Translation: CAC39615.1 .
AK314570 mRNA. Translation: BAG37151.1 .
AK315184 mRNA. Translation: BAG37625.1 .
BX537397 mRNA. Translation: CAD97639.1 .
AL049844 Genomic DNA. Translation: CAI21447.1 .
AL049844 Genomic DNA. Translation: CAB56564.1 .
CH471051 Genomic DNA. Translation: EAW47852.1 .
CH471051 Genomic DNA. Translation: EAW47853.1 .
CH471051 Genomic DNA. Translation: EAW47854.1 .
CH471051 Genomic DNA. Translation: EAW47855.1 .
CH471051 Genomic DNA. Translation: EAW47856.1 .
BC074814 mRNA. Translation: AAH74814.1 .
BC109085 mRNA. Translation: AAI09086.1 .
BC109086 mRNA. Translation: AAI09087.1 .
CCDSi CCDS5202.1. [Q9UM63-1 ]
CCDS5203.1. [Q9UM63-2 ]
RefSeqi NP_001074420.1. NM_001080951.1. [Q9UM63-1 ]
NP_001074421.1. NM_001080952.1. [Q9UM63-1 ]
NP_001074422.1. NM_001080953.1. [Q9UM63-1 ]
NP_001074423.1. NM_001080954.1. [Q9UM63-1 ]
NP_001074424.1. NM_001080955.1. [Q9UM63-2 ]
NP_001074425.1. NM_001080956.1. [Q9UM63-2 ]
NP_001275966.1. NM_001289037.1. [Q9UM63-2 ]
NP_001275967.1. NM_001289038.1. [Q9UM63-2 ]
NP_001275968.1. NM_001289039.1. [Q9UM63-2 ]
NP_001275969.1. NM_001289040.1. [Q9UM63-2 ]
NP_001275970.1. NM_001289041.1. [Q9UM63-2 ]
NP_001275971.1. NM_001289042.1. [Q9UM63-1 ]
NP_001275972.1. NM_001289043.1. [Q9UM63-1 ]
NP_001275973.1. NM_001289044.1. [Q9UM63-1 ]
NP_001275974.1. NM_001289045.1. [Q9UM63-1 ]
NP_001275975.1. NM_001289046.1. [Q9UM63-1 ]
NP_001275976.1. NM_001289047.1. [Q9UM63-1 ]
NP_001275977.1. NM_001289048.1. [Q9UM63-1 ]
NP_001275978.1. NM_001289049.1. [Q9UM63-1 ]
NP_002647.2. NM_002656.3. [Q9UM63-2 ]
NP_006709.2. NM_006718.3. [Q9UM63-1 ]
UniGenei Hs.743225.

3D structure databases

ProteinModelPortali Q9UM63.
SMRi Q9UM63. Positions 4-210.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 111341. 10 interactions.
IntActi Q9UM63. 1 interaction.
MINTi MINT-1188459.
STRINGi 9606.ENSP00000346810.

PTM databases

PhosphoSitei Q9UM63.

Polymorphism databases

DMDMi 158523334.

Proteomic databases

MaxQBi Q9UM63.
PaxDbi Q9UM63.
PRIDEi Q9UM63.

Protocols and materials databases

DNASUi 5325.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000354765 ; ENSP00000346810 ; ENSG00000118495 . [Q9UM63-1 ]
ENST00000360537 ; ENSP00000353734 ; ENSG00000118495 . [Q9UM63-1 ]
ENST00000367571 ; ENSP00000356543 ; ENSG00000118495 . [Q9UM63-1 ]
ENST00000367572 ; ENSP00000356544 ; ENSG00000118495 . [Q9UM63-2 ]
ENST00000416623 ; ENSP00000400060 ; ENSG00000118495 . [Q9UM63-1 ]
ENST00000417959 ; ENSP00000395960 ; ENSG00000118495 . [Q9UM63-2 ]
ENST00000437412 ; ENSP00000392418 ; ENSG00000118495 . [Q9UM63-2 ]
ENST00000444202 ; ENSP00000400929 ; ENSG00000118495 . [Q9UM63-1 ]
GeneIDi 5325.
KEGGi hsa:5325.
UCSCi uc003qjv.3. human. [Q9UM63-1 ]

Organism-specific databases

CTDi 5325.
GeneCardsi GC06M144261.
GeneReviewsi PLAGL1.
HGNCi HGNC:9046. PLAGL1.
HPAi HPA055706.
MIMi 603044. gene.
neXtProti NX_Q9UM63.
Orphaneti 96191. Paternal uniparental disomy of chromosome 6.
99886. Transient neonatal diabetes mellitus.
PharmGKBi PA33379.
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG5048.
GeneTreei ENSGT00390000013640.
HOVERGENi HBG053608.
InParanoidi Q9UM63.
OMAi TCGVCAL.
OrthoDBi EOG71K62Q.
PhylomeDBi Q9UM63.
TreeFami TF332024.

Miscellaneous databases

ChiTaRSi PLAGL1. human.
GeneWikii PLAGL1.
GenomeRNAii 5325.
NextBioi 20600.
PROi Q9UM63.
SOURCEi Search...

Gene expression databases

Bgeei Q9UM63.
CleanExi HS_PLAGL1.
ExpressionAtlasi Q9UM63. baseline and differential.
Genevestigatori Q9UM63.

Family and domain databases

Gene3Di 3.30.160.60. 5 hits.
InterProi IPR027775. C2H2_Znf_fam.
IPR027770. PLAGL1.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view ]
PANTHERi PTHR10032. PTHR10032. 1 hit.
PTHR10032:SF125. PTHR10032:SF125. 1 hit.
SMARTi SM00355. ZnF_C2H2. 7 hits.
[Graphical view ]
PROSITEi PS00028. ZINC_FINGER_C2H2_1. 7 hits.
PS50157. ZINC_FINGER_C2H2_2. 7 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Identification of a zinc-finger gene at 6q25: a chromosomal region implicated in development of many solid tumors."
    Abdollahi A., Roberts D., Godwin A.K., Schultz D.C., Sonoda G., Testa J.R., Hamilton T.C.
    Oncogene 14:1973-1979(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
  2. "Transcriptional activation capacity of the novel PLAG family of zinc finger proteins."
    Kas K., Voz M.L., Hensen K., Meyen E., Van de Ven W.J.M.
    J. Biol. Chem. 273:23026-23032(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
  3. "hZAC encodes a zinc finger protein with antiproliferative properties and maps to a chromosomal region frequently lost in cancer."
    Varrault A., Ciani E., Apiou F., Bilanges B., Hoffmann A., Pantaloni C., Bockaert J., Spengler D., Journot L.
    Proc. Natl. Acad. Sci. U.S.A. 95:8835-8840(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    Tissue: Pituitary.
  4. "Alternative splicing of the imprinted candidate tumor suppressor gene ZAC regulates its antiproliferative and DNA binding activities."
    Bilanges B., Varrault A., Mazumdar A., Pantaloni C., Hoffmann A., Bockaert J., Spengler D., Journot L.
    Oncogene 20:1246-1253(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), SUBCELLULAR LOCATION.
    Tissue: Mammary gland.
  5. "Characterization of the methylation-sensitive promoter of the imprinted ZAC (PLAGL1) gene supports its role in transient neonatal diabetes mellitus."
    Varrault A., Bilanges B., Mackay D.J., Basyuk E., Ahr B., Fernandez C., Robinson D.O., Bockaert J., Journot L.
    Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    Tissue: Placenta.
  6. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
    Tissue: Colon.
  7. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Tissue: Fetal kidney.
  8. "The DNA sequence and analysis of human chromosome 6."
    Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D.
    , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P., Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V., Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J., Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E., Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A., Frankland J., French L., Garner P., Garnett J., Ghori M.J., Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M., Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S., Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R., Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E., Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A., Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K., McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T., Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R., Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W., Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M., Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L., Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J., Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L., Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W., Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.
    Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  9. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  10. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Lung.
  11. "Human Spot 14 protein is a p53-dependent transcriptional coactivator via the recruitment of thyroid receptor and Zac1."
    Chou W.Y., Ho C.L., Tseng M.L., Liu S.T., Yen L.C., Huang S.M.
    Int. J. Biochem. Cell Biol. 40:1826-1834(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION, INTERACTION WITH THRSP.

Entry informationi

Entry nameiPLAL1_HUMAN
AccessioniPrimary (citable) accession number: Q9UM63
Secondary accession number(s): B2RBA4
, B2RCM8, E1P595, E1P597, O76019, Q7Z3V8, Q92981, Q96JR9, Q9UIZ0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 20, 2001
Last sequence update: September 11, 2007
Last modified: October 29, 2014
This is version 126 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3