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Q9UM45

- Q9UM45_HUMAN

UniProt

Q9UM45 - Q9UM45_HUMAN

Protein
Submitted name:

MHC-G

Gene

HLA

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 80 (01 Oct 2014)
      Sequence version 1 (01 May 2000)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. peptide antigen binding Source: InterPro

    GO - Biological processi

    1. antigen processing and presentation of peptide antigen via MHC class I Source: InterPro
    2. immune response Source: InterPro
    3. positive regulation of T cell mediated cytotoxicity Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    MHC-GImported
    Gene namesi
    Name:HLAImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. MHC class I protein complex Source: InterPro

    PTM / Processingi

    Proteomic databases

    PRIDEiQ9UM45.

    Expressioni

    Gene expression databases

    ArrayExpressiQ9UM45.
    BgeeiQ9UM45.

    Interactioni

    Protein-protein interaction databases

    STRINGi9606.ENSP00000353472.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9UM45.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the MHC class I family.UniRule annotation
    Contains Ig-like C1-type (immunoglobulin-like) domain.SAAS annotation

    Phylogenomic databases

    HOVERGENiHBG016709.

    Family and domain databases

    Gene3Di2.60.40.10. 1 hit.
    3.30.500.10. 1 hit.
    InterProiIPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR003006. Ig/MHC_CS.
    IPR003597. Ig_C1-set.
    IPR011161. MHC_I-like_Ag-recog.
    IPR011162. MHC_I/II-like_Ag-recog.
    IPR027648. MHC_I_a.
    IPR001039. MHC_I_a_a1/a2.
    [Graphical view]
    PfamiPF07654. C1-set. 1 hit.
    PF00129. MHC_I. 1 hit.
    [Graphical view]
    PRINTSiPR01638. MHCCLASSI.
    SMARTiSM00407. IGc1. 1 hit.
    [Graphical view]
    SUPFAMiSSF54452. SSF54452. 1 hit.
    PROSITEiPS50835. IG_LIKE. 1 hit.
    PS00290. IG_MHC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q9UM45-1 [UniParc]FASTAAdd to Basket

    « Hide

    AVSRPGRGEP RFIAMGYVDD TQFVRFDSDS ACPRMEPRAP WVEQEGPEYW    50
    EEETRNTKAH AQTDRMNLQT LRGYYNQSEA SSHTLQWMIG CDLGSDGRLL 100
    RGYEQYAYDG KDYLALNEDL RSWTAADTAA QISKRKCEAA NVAEQRRAYL 150
    EGTCVEWLHR YLENGKEMLQ RADPPKTHVT HHPVFDYEAT LRCWALGFYP 200
    AEIILTWQRD GEDQTQDVEL VETRPAGDGT FQKWAAVVVP SGEEQRYTCH 250
    VQHEGLPEPL MLRWKQSSLP TIPIMGIVAG LVVLAAVVTG AAVAAVLWRK 300
    KSSD 304
    Length:304
    Mass (Da):34,483
    Last modified:May 1, 2000 - v1
    Checksum:iE0852C2FF65F9E3A
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U88244 mRNA. Translation: AAD45397.1.
    UniGeneiHs.512152.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U88244 mRNA. Translation: AAD45397.1 .
    UniGenei Hs.512152.

    3D structure databases

    ProteinModelPortali Q9UM45.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9606.ENSP00000353472.

    Proteomic databases

    PRIDEi Q9UM45.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG016709.

    Gene expression databases

    ArrayExpressi Q9UM45.
    Bgeei Q9UM45.

    Family and domain databases

    Gene3Di 2.60.40.10. 1 hit.
    3.30.500.10. 1 hit.
    InterProi IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR003006. Ig/MHC_CS.
    IPR003597. Ig_C1-set.
    IPR011161. MHC_I-like_Ag-recog.
    IPR011162. MHC_I/II-like_Ag-recog.
    IPR027648. MHC_I_a.
    IPR001039. MHC_I_a_a1/a2.
    [Graphical view ]
    Pfami PF07654. C1-set. 1 hit.
    PF00129. MHC_I. 1 hit.
    [Graphical view ]
    PRINTSi PR01638. MHCCLASSI.
    SMARTi SM00407. IGc1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54452. SSF54452. 1 hit.
    PROSITEi PS50835. IG_LIKE. 1 hit.
    PS00290. IG_MHC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Castro M., Morales P., Arnaiz-Villena A.
      Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: 4510.G1Imported.
    2. "Lack of HLA-G soluble isoforms in Graves-Basedow thyrocytes and complete cDNA sequence of the HLA-G*01012 allele."
      Castro M.J., Morales P., Catalfamo M., Fernandez-Soria V., Suarez B., Varela P., Perez-Blas M., Alvarez M., Jaraquemada D., Arnaiz-Villena A.
      Eur. J. Immunogenet. 25:311-315(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: 4510.G1Imported.

    Entry informationi

    Entry nameiQ9UM45_HUMAN
    AccessioniPrimary (citable) accession number: Q9UM45
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 1, 2000
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 80 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.