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Q9UM45

- Q9UM45_HUMAN

UniProt

Q9UM45 - Q9UM45_HUMAN

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Protein
Submitted name:

MHC-G

Gene

HLA

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. peptide antigen binding Source: InterPro

GO - Biological processi

  1. antigen processing and presentation of peptide antigen via MHC class I Source: InterPro
  2. immune response Source: InterPro
  3. positive regulation of T cell mediated cytotoxicity Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
MHC-GImported
Gene namesi
Name:HLAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. MHC class I protein complex Source: InterPro
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ9UM45.

Expressioni

Gene expression databases

BgeeiQ9UM45.
ExpressionAtlasiQ9UM45. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000353472.

Structurei

3D structure databases

ProteinModelPortaliQ9UM45.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MHC class I family.UniRule annotation
Contains Ig-like C1-type (immunoglobulin-like) domain.SAAS annotation

Phylogenomic databases

HOVERGENiHBG016709.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR027648. MHC_I_a.
IPR001039. MHC_I_a_a1/a2.
[Graphical view]
PfamiPF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
[Graphical view]
PRINTSiPR01638. MHCCLASSI.
SMARTiSM00407. IGc1. 1 hit.
[Graphical view]
SUPFAMiSSF54452. SSF54452. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9UM45-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
AVSRPGRGEP RFIAMGYVDD TQFVRFDSDS ACPRMEPRAP WVEQEGPEYW
60 70 80 90 100
EEETRNTKAH AQTDRMNLQT LRGYYNQSEA SSHTLQWMIG CDLGSDGRLL
110 120 130 140 150
RGYEQYAYDG KDYLALNEDL RSWTAADTAA QISKRKCEAA NVAEQRRAYL
160 170 180 190 200
EGTCVEWLHR YLENGKEMLQ RADPPKTHVT HHPVFDYEAT LRCWALGFYP
210 220 230 240 250
AEIILTWQRD GEDQTQDVEL VETRPAGDGT FQKWAAVVVP SGEEQRYTCH
260 270 280 290 300
VQHEGLPEPL MLRWKQSSLP TIPIMGIVAG LVVLAAVVTG AAVAAVLWRK

KSSD
Length:304
Mass (Da):34,483
Last modified:May 1, 2000 - v1
Checksum:iE0852C2FF65F9E3A
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U88244 mRNA. Translation: AAD45397.1.
UniGeneiHs.512152.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U88244 mRNA. Translation: AAD45397.1 .
UniGenei Hs.512152.

3D structure databases

ProteinModelPortali Q9UM45.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9606.ENSP00000353472.

Proteomic databases

PRIDEi Q9UM45.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOVERGENi HBG016709.

Gene expression databases

Bgeei Q9UM45.
ExpressionAtlasi Q9UM45. baseline and differential.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProi IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR027648. MHC_I_a.
IPR001039. MHC_I_a_a1/a2.
[Graphical view ]
Pfami PF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
[Graphical view ]
PRINTSi PR01638. MHCCLASSI.
SMARTi SM00407. IGc1. 1 hit.
[Graphical view ]
SUPFAMi SSF54452. SSF54452. 1 hit.
PROSITEi PS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Castro M., Morales P., Arnaiz-Villena A.
    Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 4510.G1Imported.
  2. "Lack of HLA-G soluble isoforms in Graves-Basedow thyrocytes and complete cDNA sequence of the HLA-G*01012 allele."
    Castro M.J., Morales P., Catalfamo M., Fernandez-Soria V., Suarez B., Varela P., Perez-Blas M., Alvarez M., Jaraquemada D., Arnaiz-Villena A.
    Eur. J. Immunogenet. 25:311-315(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 4510.G1Imported.

Entry informationi

Entry nameiQ9UM45_HUMAN
AccessioniPrimary (citable) accession number: Q9UM45
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: October 29, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.