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Q9ULV3

- CIZ1_HUMAN

UniProt

Q9ULV3 - CIZ1_HUMAN

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Protein

Cip1-interacting zinc finger protein

Gene

CIZ1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

May regulate the subcellular localization of CIP/WAF1.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri799 – 83032Matrin-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  1. nucleic acid binding Source: InterPro
  2. zinc ion binding Source: ProtInc

GO - Biological processi

  1. maintenance of protein location in nucleus Source: Ensembl
  2. positive regulation of DNA-dependent DNA replication initiation Source: Ensembl
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Cip1-interacting zinc finger protein
Alternative name(s):
CDKN1A-interacting zinc finger protein 1
Nuclear protein NP94
Zinc finger protein 356
Gene namesi
Name:CIZ1
Synonyms:LSFR1, NP94, ZNF356
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 9

Organism-specific databases

HGNCiHGNC:16744. CIZ1.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: ProtInc
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Involvement in diseasei

Defects in CIZ1 may be a cause of adult onset primary cervical dystonia. Dystonia is defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures. Cervical dystonia or spasmodic torticollis, the most common form of focal dystonia, is characterized by involuntary contractions of the neck muscles, which produce abnormal posturing of the head upon the trunk.

Keywords - Diseasei

Disease mutation, Dystonia

Organism-specific databases

PharmGKBiPA134883336.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 898898Cip1-interacting zinc finger proteinPRO_0000089776Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei567 – 5671Phosphothreonine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ9ULV3.
PaxDbiQ9ULV3.
PRIDEiQ9ULV3.

PTM databases

PhosphoSiteiQ9ULV3.

Expressioni

Gene expression databases

BgeeiQ9ULV3.
CleanExiHS_CIZ1.
ExpressionAtlasiQ9ULV3. baseline and differential.
GenevestigatoriQ9ULV3.

Organism-specific databases

HPAiHPA020380.
HPA020384.
HPA020387.

Interactioni

Subunit structurei

Interacts with CIP/WAF1.

Binary interactionsi

WithEntry#Exp.IntActNotes
SH3BP4Q9P0V32EBI-2652948,EBI-1049513

Protein-protein interaction databases

BioGridi117325. 13 interactions.
IntActiQ9ULV3. 7 interactions.
STRINGi9606.ENSP00000362029.

Structurei

3D structure databases

ProteinModelPortaliQ9ULV3.
SMRiQ9ULV3. Positions 655-706.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi4 – 4441Gln-richAdd
BLAST
Compositional biasi276 – 470195Gln-richAdd
BLAST
Compositional biasi741 – 76121Glu-richAdd
BLAST

Sequence similaritiesi

Contains 1 matrin-type zinc finger.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri799 – 83032Matrin-typePROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiNOG70338.
GeneTreeiENSGT00440000039084.
HOVERGENiHBG002558.
InParanoidiQ9ULV3.
OrthoDBiEOG75F4G0.
PhylomeDBiQ9ULV3.
TreeFamiTF332388.

Family and domain databases

InterProiIPR026811. CIZ1.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR022755. Znf_C2H2_jaz.
IPR000690. Znf_C2H2_matrin.
IPR003604. Znf_U1.
[Graphical view]
PANTHERiPTHR15491:SF9. PTHR15491:SF9. 1 hit.
PfamiPF12171. zf-C2H2_jaz. 1 hit.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 3 hits.
SM00451. ZnF_U1. 3 hits.
[Graphical view]
PROSITEiPS50171. ZF_MATRIN. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 2 hits.
[Graphical view]

Sequences (5)i

Sequence statusi: Complete.

This entry describes 5 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q9ULV3-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MFSQQQQQQL QQQQQQLQQL QQQQLQQQQL QQQQLLQLQQ LLQQSPPQAP
60 70 80 90 100
LPMAVSRGLP PQQPQQPLLN LQGTNSASLL NGSMLQRALL LQQLQGLDQF
110 120 130 140 150
AMPPATYDTA GLTMPTATLG NLRGYGMASP GLAAPSLTPP QLATPNLQQF
160 170 180 190 200
FPQATRQSLL GPPPVGVPMN PSQFNLSGRN PQKQARTSSS TTPNRKDSSS
210 220 230 240 250
QTMPVEDKSD PPEGSEEAAE PRMDTPEDQD LPPCPEDIAK EKRTPAPEPE
260 270 280 290 300
PCEASELPAK RLRSSEEPTE KEPPGQLQVK AQPQARMTVP KQTQTPDLLP
310 320 330 340 350
EALEAQVLPR FQPRVLQVQA QVQSQTQPRI PSTDTQVQPK LQKQAQTQTS
360 370 380 390 400
PEHLVLQQKQ VQPQLQQEAE PQKQVQPQVQ PQAHSQGPRQ VQLQQEAEPL
410 420 430 440 450
KQVQPQVQPQ AHSQPPRQVQ LQLQKQVQTQ TYPQVHTQAQ PSVQPQEHPP
460 470 480 490 500
AQVSVQPPEQ THEQPHTQPQ VSLLAPEQTP VVVHVCGLEM PPDAVEAGGG
510 520 530 540 550
MEKTLPEPVG TQVSMEEIQN ESACGLDVGE CENRAREMPG VWGAGGSLKV
560 570 580 590 600
TILQSSDSRA FSTVPLTPVP RPSDSVSSTP AATSTPSKQA LQFFCYICKA
610 620 630 640 650
SCSSQQEFQD HMSEPQHQQR LGEIQHMSQA CLLSLLPVPR DVLETEDEEP
660 670 680 690 700
PPRRWCNTCQ LYYMGDLIQH RRTQDHKIAK QSLRPFCTVC NRYFKTPRKF
710 720 730 740 750
VEHVKSQGHK DKAKELKSLE KEIAGQDEDH FITVDAVGCF EGDEEEEEDD
760 770 780 790 800
EDEEEIEVEE ELCKQVRSRD ISREEWKGSE TYSPNTAYGV DFLVPVMGYI
810 820 830 840 850
CRICHKFYHS NSGAQLSHCK SLGHFENLQK YKAAKNPSPT TRPVSRRCAI
860 870 880 890
NARNALTALF TSSGRPPSQP NTQDKTPSKV TARPSQPPLP RRSTRLKT
Length:898
Mass (Da):100,045
Last modified:May 18, 2010 - v2
Checksum:i5E14389E81A146F1
GO
Isoform 2 (identifier: Q9ULV3-2) [UniParc]FASTAAdd to Basket

Also known as: NP94B

The sequence of this isoform differs from the canonical sequence as follows:
     97-120: Missing.
     197-201: Missing.

Show »
Length:869
Mass (Da):97,075
Checksum:iACCB3ABBE6A91F03
GO
Isoform 3 (identifier: Q9ULV3-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     97-120: Missing.
     377-432: Missing.

Show »
Length:818
Mass (Da):91,153
Checksum:i28DBDF0FB222820E
GO
Isoform 4 (identifier: Q9ULV3-4) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     377-432: Missing.

Show »
Length:842
Mass (Da):93,619
Checksum:iC799C715E082C006
GO
Isoform 5 (identifier: Q9ULV3-5) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-101: Missing.

Note: No experimental confirmation available.

Show »
Length:797
Mass (Da):88,520
Checksum:i1C3805A4CFAC8864
GO

Sequence cautioni

The sequence AAF23231.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence AAF37882.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti9 – 91Missing in AAF23231. (PubMed:12824700)Curated
Sequence conflicti35 – 351L → S in AAF23231. (PubMed:12824700)Curated
Sequence conflicti101 – 1011A → V in BAB14750. (PubMed:14702039)Curated
Sequence conflicti232 – 2321P → L in BAA85783. (PubMed:10529385)Curated
Sequence conflicti500 – 5001G → S in AAF37882. (PubMed:12824700)Curated
Sequence conflicti549 – 5491K → E in BAG64643. (PubMed:14702039)Curated
Sequence conflicti555 – 5551S → G in BAA85783. (PubMed:10529385)Curated
Sequence conflicti568 – 5681P → L in AAF23231. (PubMed:12824700)Curated
Sequence conflicti634 – 6341S → P in AAF23231. (PubMed:12824700)Curated
Sequence conflicti677 – 6771K → R in AAF37882. (PubMed:12824700)Curated
Sequence conflicti678 – 6781I → V in BAB14750. (PubMed:14702039)Curated
Sequence conflicti682 – 6821S → P in BAB14750. (PubMed:14702039)Curated
Sequence conflicti698 – 6981R → L in CAB44346. (PubMed:10369878)Curated
Sequence conflicti735 – 7351D → G in AAF23231. (PubMed:12824700)Curated
Sequence conflicti757 – 7571E → K in BAB14750. (PubMed:14702039)Curated
Sequence conflicti810 – 8101S → N in AAF37882. (PubMed:12824700)Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti47 – 471P → S Probable disease-associated mutation found in patients with adult onset primary cervical dystonia. 1 Publication
VAR_067971
Natural varianti50 – 501P → L.1 Publication
VAR_067972
Natural varianti219 – 2191A → T.1 Publication
Corresponds to variant rs45588035 [ dbSNP | Ensembl ].
VAR_056820
Natural varianti264 – 2641S → G Probable disease-associated mutation found in a family with adult onset primary cervical dystonia; exonic splicing enhancer mutation resulting in altered CIZ1 splicing pattern. 1 Publication
VAR_067973
Natural varianti370 – 3701E → G.1 Publication
Corresponds to variant rs45554035 [ dbSNP | Ensembl ].
VAR_063105
Natural varianti394 – 3941Q → E.1 Publication
VAR_067974
Natural varianti577 – 5771S → F.1 Publication
VAR_067975
Natural varianti578 – 5781S → F.1 Publication
Corresponds to variant rs12334 [ dbSNP | Ensembl ].
VAR_056821
Natural varianti638 – 6381V → M.2 Publications
Corresponds to variant rs11549266 [ dbSNP | Ensembl ].
VAR_056822
Natural varianti672 – 6721R → M Probable disease-associated mutation found in patients with adult onset primary cervical dystonia. 1 Publication
VAR_067976
Natural varianti847 – 8471R → Q.1 Publication
Corresponds to variant rs11549260 [ dbSNP | Ensembl ].
VAR_063106

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 101101Missing in isoform 5. 1 PublicationVSP_044729Add
BLAST
Alternative sequencei97 – 12024Missing in isoform 2 and isoform 3. 2 PublicationsVSP_004164Add
BLAST
Alternative sequencei197 – 2015Missing in isoform 2. 1 PublicationVSP_004165
Alternative sequencei377 – 43256Missing in isoform 3 and isoform 4. 2 PublicationsVSP_039894Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB030835 mRNA. Translation: BAA85783.1.
EF467915 Genomic DNA. Translation: ABO43037.1.
AK023978 mRNA. Translation: BAB14750.1.
AK292713 mRNA. Translation: BAF85402.1.
AK303636 mRNA. Translation: BAG64643.1.
AK316393 mRNA. Translation: BAH14764.1.
AL590708 Genomic DNA. Translation: CAI13828.1.
AL590708 Genomic DNA. Translation: CAI13829.1.
AL590708 Genomic DNA. Translation: CAI13831.1.
CH471090 Genomic DNA. Translation: EAW87752.1.
CH471090 Genomic DNA. Translation: EAW87753.1.
CH471090 Genomic DNA. Translation: EAW87754.1.
BC021163 mRNA. Translation: AAH21163.1.
AF159027 mRNA. Translation: AAF23231.1. Different initiation.
AF234161 mRNA. Translation: AAF37882.1. Different initiation.
Y17453 Genomic DNA. Translation: CAB44346.1.
Y17454 Genomic DNA. Translation: CAB44347.1.
CCDSiCCDS48033.1. [Q9ULV3-3]
CCDS48034.1. [Q9ULV3-4]
CCDS6894.1. [Q9ULV3-1]
RefSeqiNP_001124487.1. NM_001131015.1. [Q9ULV3-4]
NP_001124488.1. NM_001131016.1. [Q9ULV3-1]
NP_001124489.1. NM_001131017.1.
NP_001124490.1. NM_001131018.1. [Q9ULV3-3]
NP_001244904.1. NM_001257975.1.
NP_001244905.1. NM_001257976.1. [Q9ULV3-5]
NP_036259.2. NM_012127.2. [Q9ULV3-1]
UniGeneiHs.212395.

Genome annotation databases

EnsembliENST00000357558; ENSP00000350169; ENSG00000148337. [Q9ULV3-4]
ENST00000372938; ENSP00000362029; ENSG00000148337. [Q9ULV3-1]
ENST00000372948; ENSP00000362039; ENSG00000148337. [Q9ULV3-4]
ENST00000372954; ENSP00000362045; ENSG00000148337. [Q9ULV3-3]
GeneIDi25792.
KEGGihsa:25792.
UCSCiuc004bts.3. human. [Q9ULV3-2]
uc004btt.3. human. [Q9ULV3-1]
uc004btu.3. human. [Q9ULV3-3]
uc004btw.3. human. [Q9ULV3-4]

Polymorphism databases

DMDMi296434448.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Web resourcesi

NIEHS-SNPs

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB030835 mRNA. Translation: BAA85783.1 .
EF467915 Genomic DNA. Translation: ABO43037.1 .
AK023978 mRNA. Translation: BAB14750.1 .
AK292713 mRNA. Translation: BAF85402.1 .
AK303636 mRNA. Translation: BAG64643.1 .
AK316393 mRNA. Translation: BAH14764.1 .
AL590708 Genomic DNA. Translation: CAI13828.1 .
AL590708 Genomic DNA. Translation: CAI13829.1 .
AL590708 Genomic DNA. Translation: CAI13831.1 .
CH471090 Genomic DNA. Translation: EAW87752.1 .
CH471090 Genomic DNA. Translation: EAW87753.1 .
CH471090 Genomic DNA. Translation: EAW87754.1 .
BC021163 mRNA. Translation: AAH21163.1 .
AF159027 mRNA. Translation: AAF23231.1 . Different initiation.
AF234161 mRNA. Translation: AAF37882.1 . Different initiation.
Y17453 Genomic DNA. Translation: CAB44346.1 .
Y17454 Genomic DNA. Translation: CAB44347.1 .
CCDSi CCDS48033.1. [Q9ULV3-3 ]
CCDS48034.1. [Q9ULV3-4 ]
CCDS6894.1. [Q9ULV3-1 ]
RefSeqi NP_001124487.1. NM_001131015.1. [Q9ULV3-4 ]
NP_001124488.1. NM_001131016.1. [Q9ULV3-1 ]
NP_001124489.1. NM_001131017.1.
NP_001124490.1. NM_001131018.1. [Q9ULV3-3 ]
NP_001244904.1. NM_001257975.1.
NP_001244905.1. NM_001257976.1. [Q9ULV3-5 ]
NP_036259.2. NM_012127.2. [Q9ULV3-1 ]
UniGenei Hs.212395.

3D structure databases

ProteinModelPortali Q9ULV3.
SMRi Q9ULV3. Positions 655-706.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 117325. 13 interactions.
IntActi Q9ULV3. 7 interactions.
STRINGi 9606.ENSP00000362029.

PTM databases

PhosphoSitei Q9ULV3.

Polymorphism databases

DMDMi 296434448.

Proteomic databases

MaxQBi Q9ULV3.
PaxDbi Q9ULV3.
PRIDEi Q9ULV3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000357558 ; ENSP00000350169 ; ENSG00000148337 . [Q9ULV3-4 ]
ENST00000372938 ; ENSP00000362029 ; ENSG00000148337 . [Q9ULV3-1 ]
ENST00000372948 ; ENSP00000362039 ; ENSG00000148337 . [Q9ULV3-4 ]
ENST00000372954 ; ENSP00000362045 ; ENSG00000148337 . [Q9ULV3-3 ]
GeneIDi 25792.
KEGGi hsa:25792.
UCSCi uc004bts.3. human. [Q9ULV3-2 ]
uc004btt.3. human. [Q9ULV3-1 ]
uc004btu.3. human. [Q9ULV3-3 ]
uc004btw.3. human. [Q9ULV3-4 ]

Organism-specific databases

CTDi 25792.
GeneCardsi GC09M130929.
HGNCi HGNC:16744. CIZ1.
HPAi HPA020380.
HPA020384.
HPA020387.
MIMi 611420. gene.
neXtProti NX_Q9ULV3.
PharmGKBi PA134883336.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG70338.
GeneTreei ENSGT00440000039084.
HOVERGENi HBG002558.
InParanoidi Q9ULV3.
OrthoDBi EOG75F4G0.
PhylomeDBi Q9ULV3.
TreeFami TF332388.

Miscellaneous databases

ChiTaRSi CIZ1. human.
GeneWikii CIZ1.
GenomeRNAii 25792.
NextBioi 46965.
PROi Q9ULV3.
SOURCEi Search...

Gene expression databases

Bgeei Q9ULV3.
CleanExi HS_CIZ1.
ExpressionAtlasi Q9ULV3. baseline and differential.
Genevestigatori Q9ULV3.

Family and domain databases

InterProi IPR026811. CIZ1.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR022755. Znf_C2H2_jaz.
IPR000690. Znf_C2H2_matrin.
IPR003604. Znf_U1.
[Graphical view ]
PANTHERi PTHR15491:SF9. PTHR15491:SF9. 1 hit.
Pfami PF12171. zf-C2H2_jaz. 1 hit.
[Graphical view ]
SMARTi SM00355. ZnF_C2H2. 3 hits.
SM00451. ZnF_U1. 3 hits.
[Graphical view ]
PROSITEi PS50171. ZF_MATRIN. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning and characterization of a novel p21(Cip1/Waf1)-interacting zinc finger protein, ciz1."
    Mitsui K., Matsumoto A., Ohtsuka S., Ohtsubo M., Yoshimura A.
    Biochem. Biophys. Res. Commun. 264:457-464(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
  2. NIEHS SNPs program
    Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANTS THR-219; GLY-370; PHE-578; MET-638 AND GLN-847.
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 4 AND 5), VARIANT MET-638.
    Tissue: Testis and Thymus.
  4. "DNA sequence and analysis of human chromosome 9."
    Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L.
    , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
    Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
    Tissue: Lymph.
  7. "Ciz1, Cip1 interacting zinc finger protein 1 binds the consensus DNA sequence ARYSR(0-2)YYAC."
    Warder D.E., Keherly M.J.
    J. Biomed. Sci. 10:406-417(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2-898 (ISOFORM 1), NUCLEOTIDE SEQUENCE [MRNA] OF 50-898 (ISOFORM 2).
    Tissue: Medulloblastoma.
  8. "Extensive gene order differences within regions of conserved synteny between the Fugu and human genomes: implications for chromosomal evolution and the cloning of disease genes."
    Gilley J., Fried M.
    Hum. Mol. Genet. 8:1313-1320(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 649-898.
  9. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  10. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-567, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  11. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  12. Cited for: POSSIBLE INVOLVEMENT IN ADULT ONSET PRIMARY CERVICAL DYSTONIA, VARIANTS SER-47; LEU-50; GLY-264; GLU-394; PHE-577 AND MET-672.

Entry informationi

Entry nameiCIZ1_HUMAN
AccessioniPrimary (citable) accession number: Q9ULV3
Secondary accession number(s): A8K9J8
, B4E131, B7ZAS8, Q5SYW3, Q5SYW5, Q8WU72, Q9H868, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 24, 2001
Last sequence update: May 18, 2010
Last modified: October 29, 2014
This is version 122 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3