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Q9ULV0

- MYO5B_HUMAN

UniProt

Q9ULV0 - MYO5B_HUMAN

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Protein
Unconventional myosin-Vb
Gene
MYO5B, KIAA1119
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

May be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis By similarity.3 Publications

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi163 – 1708ATP Reviewed prediction

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. Rab GTPase binding Source: UniProtKB
  3. microfilament motor activity Source: Reactome
  4. protein binding Source: UniProtKB

GO - Biological processi

  1. metabolic process Source: GOC
  2. protein transport Source: UniProtKB-KW
  3. transmembrane transport Source: Reactome
  4. vesicle-mediated transport Source: UniProtKB
  5. water transport Source: Reactome
Complete GO annotation...

Keywords - Molecular functioni

Motor protein, Myosin

Keywords - Biological processi

Protein transport, Transport

Keywords - Ligandi

Actin-binding, ATP-binding, Calmodulin-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiREACT_24023. Regulation of water balance by renal Aquaporins.

Names & Taxonomyi

Protein namesi
Recommended name:
Unconventional myosin-Vb
Gene namesi
Name:MYO5B
Synonyms:KIAA1119
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 18

Organism-specific databases

HGNCiHGNC:7603. MYO5B.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasmic vesicle membrane Source: Reactome
  2. extracellular vesicular exosome Source: UniProt
  3. myosin complex Source: UniProtKB-KW
  4. protein complex Source: UniProtKB
Complete GO annotation...

Pathology & Biotechi

Involvement in diseasei

Diarrhea 2, with microvillus atrophy (DIAR2) [MIM:251850]: A disease characterized by onset of intractable life-threatening watery diarrhea during infancy. Two forms are recognized: early-onset microvillus inclusion disease with diarrhea beginning in the neonatal period, and late-onset, with first symptoms appearing after 3 or 4 months of life.
Note: The disease is caused by mutations affecting the gene represented in this entry.1 Publication
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti108 – 1081V → G in DIAR2. 1 Publication
VAR_054993
Natural varianti219 – 2191R → H in DIAR2. 1 Publication
VAR_054994
Natural varianti656 – 6561R → C in DIAR2. 1 Publication
VAR_054995

Mutagenesis

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Mutagenesisi1300 – 13001Q → L: Abolishes interaction with RAB8A and has no effect on RAB11A interaction; when associated with C-1307. 1 Publication
Mutagenesisi1307 – 13071Y → C: Abolishes interaction with RAB8A and has no effect on RAB11A interaction; when associated with L-1300. 1 Publication
Mutagenesisi1714 – 17141Y → E: Abolishes interaction with RAB11A; has no effect on RAB8A interaction. 1 Publication
Mutagenesisi1748 – 17481Q → R: Abolishes interaction with RAB11A; has no effect on RAB8A interaction. 1 Publication

Keywords - Diseasei

Disease mutation

Organism-specific databases

MIMi251850. phenotype.
Orphaneti2290. Microvillous inclusion disease.
PharmGKBiPA31408.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 18481848Unconventional myosin-Vb
PRO_0000123460Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1446 – 14461Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ9ULV0.
PaxDbiQ9ULV0.
PRIDEiQ9ULV0.

PTM databases

PhosphoSiteiQ9ULV0.

Expressioni

Gene expression databases

ArrayExpressiQ9ULV0.
BgeeiQ9ULV0.
CleanExiHS_MYO5B.
GenevestigatoriQ9ULV0.

Organism-specific databases

HPAiHPA040593.
HPA040902.

Interactioni

Subunit structurei

Component of the CART complex, at least composed of ACTN4, HGS/HRS, MYO5B and TRIM3. Interacts with RAB11FIP2, RAB11A, and RAB8A. Found in a complex with CFTR and RAB11A. Interacts with NPC1L1.5 Publications

Protein-protein interaction databases

BioGridi110729. 10 interactions.
IntActiQ9ULV0. 4 interactions.
MINTiMINT-1209283.
STRINGi9606.ENSP00000285039.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi1468 – 14714
Helixi1474 – 14763
Helixi1477 – 14848
Turni1485 – 14873
Helixi1490 – 14934
Helixi1500 – 151415
Helixi1518 – 153821
Turni1539 – 15413
Helixi1543 – 156220
Helixi1567 – 15693
Helixi1575 – 15784
Helixi1588 – 161326
Helixi1614 – 16163
Helixi1617 – 16226
Helixi1654 – 167017
Helixi1675 – 169925
Helixi1701 – 17033
Helixi1706 – 172520
Helixi1729 – 17313
Helixi1733 – 17364
Helixi1738 – 17469
Helixi1754 – 176310
Helixi1769 – 177810
Helixi1791 – 180010
Turni1801 – 18033
Helixi1831 – 18333
Helixi1838 – 18403
Beta strandi1845 – 18484

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4J5MX-ray2.07A1453-1848[»]
4LNZX-ray3.11A1460-1848[»]
4LWZX-ray2.55B/D1456-1848[»]
4LX0X-ray2.19B/D1456-1848[»]
ProteinModelPortaliQ9ULV0.
SMRiQ9ULV0. Positions 5-816, 858-898, 1456-1848.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini69 – 761693Myosin motor
Add
BLAST
Domaini769 – 79830IQ 1
Add
BLAST
Domaini792 – 82130IQ 2
Add
BLAST
Domaini817 – 84832IQ 3
Add
BLAST
Domaini840 – 86930IQ 4
Add
BLAST
Domaini865 – 89632IQ 5
Add
BLAST
Domaini888 – 91730IQ 6
Add
BLAST
Domaini1526 – 1803278Dilute
Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni640 – 66223Actin-binding Reviewed prediction
Add
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili899 – 1266368 Reviewed prediction
Add
BLAST
Coiled coili1341 – 1471131 Reviewed prediction
Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi801 – 916116Arg-rich
Add
BLAST

Sequence similaritiesi

Contains 1 dilute domain.
Contains 6 IQ domains.

Keywords - Domaini

Coiled coil, Repeat

Phylogenomic databases

eggNOGiCOG5022.
HOGENOMiHOG000171839.
HOVERGENiHBG052556.
InParanoidiQ9ULV0.
KOiK10357.
OMAiQTMEPLI.
OrthoDBiEOG7PK8XT.
PhylomeDBiQ9ULV0.
TreeFamiTF328771.

Family and domain databases

InterProiIPR018444. Dil_domain.
IPR002710. Dilute.
IPR000048. IQ_motif_EF-hand-BS.
IPR001609. Myosin_head_motor_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF01843. DIL. 1 hit.
PF00612. IQ. 6 hits.
PF00063. Myosin_head. 1 hit.
[Graphical view]
PRINTSiPR00193. MYOSINHEAVY.
SMARTiSM00015. IQ. 6 hits.
SM00242. MYSc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS51126. DILUTE. 1 hit.
PS50096. IQ. 6 hits.
PS51456. MYOSIN_MOTOR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9ULV0-1 [UniParc]FASTAAdd to Basket

« Hide

MSVGELYSQC TRVWIPDPDE VWRSAELTKD YKEGDKSLQL RLEDETILEY     50
PIDVQRNQLP FLRNPDILVG ENDLTALSYL HEPAVLHNLK VRFLESNHIY 100
TYCGIVLVAI NPYEQLPIYG QDVIYTYSGQ NMGDMDPHIF AVAEEAYKQM 150
ARDEKNQSII VSGESGAGKT VSAKYAMRYF ATVGGSASET NIEEKVLASS 200
PIMEAIGNAK TTRNDNSSRF GKYIQIGFDK RYHIIGANMR TYLLEKSRVV 250
FQADDERNYH IFYQLCAAAG LPEFKELALT SAEDFFYTSQ GGDTSIEGVD 300
DAEDFEKTRQ AFTLLGVKES HQMSIFKIIA SILHLGSVAI QAERDGDSCS 350
ISPQDVYLSN FCRLLGVEHS QMEHWLCHRK LVTTSETYVK TMSLQQVINA 400
RNALAKHIYA QLFGWIVEHI NKALHTSLKQ HSFIGVLDIY GFETFEVNSF 450
EQFCINYANE KLQQQFNSHV FKLEQEEYMK EQIPWTLIDF YDNQPCIDLI 500
EAKLGILDLL DEECKVPKGT DQNWAQKLYD RHSSSQHFQK PRMSNTAFII 550
VHFADKVEYL SDGFLEKNRD TVYEEQINIL KASKFPLVAD LFHDDKDPVP 600
ATTPGKGSSS KISVRSARPP MKVSNKEHKK TVGHQFRTSL HLLMETLNAT 650
TPHYVRCIKP NDEKLPFHFD PKRAVQQLRA CGVLETIRIS AAGYPSRWAY 700
HDFFNRYRVL VKKRELANTD KKAICRSVLE NLIKDPDKFQ FGRTKIFFRA 750
GQVAYLEKLR ADKFRTATIM IQKTVRGWLQ KVKYHRLKGA TLTLQRYCRG 800
HLARRLAEHL RRIRAAVVLQ KHYRMQRARQ AYQRVRRAAV VIQAFTRAMF 850
VRRTYRQVLM EHKATTIQKH VRGWMARRHF QRLRDAAIVI QCAFRMLKAR 900
RELKALRIEA RSAEHLKRLN VGMENKVVQL QRKIDEQNKE FKTLSEQLSV 950
TTSTYTMEVE RLKKELVHYQ QSPGEDTSLR LQEEVESLRT ELQRAHSERK 1000
ILEDAHSREK DELRKRVADL EQENALLKDE KEQLNNQILC QSKDEFAQNS 1050
VKENLMKKEL EEERSRYQNL VKEYSQLEQR YDNLRDEMTI IKQTPGHRRN 1100
PSNQSSLESD SNYPSISTSE IGDTEDALQQ VEEIGLEKAA MDMTVFLKLQ 1150
KRVRELEQER KKLQVQLEKR EQQDSKKVQA EPPQTDIDLD PNADLAYNSL 1200
KRQELESENK KLKNDLNELR KAVADQATQN NSSHGSPDSY SLLLNQLKLA 1250
HEELEVRKEE VLILRTQIVS ADQRRLAGRN AEPNINARSS WPNSEKHVDQ 1300
EDAIEAYHGV CQTNSKTEDW GYLNEDGELG LAYQGLKQVA RLLEAQLQAQ 1350
SLEHEEEVEH LKAQLEALKE EMDKQQQTFC QTLLLSPEAQ VEFGVQQEIS 1400
RLTNENLDLK ELVEKLEKNE RKLKKQLKIY MKKAQDLEAA QALAQSERKR 1450
HELNRQVTVQ RKEKDFQGML EYHKEDEALL IRNLVTDLKP QMLSGTVPCL 1500
PAYILYMCIR HADYTNDDLK VHSLLTSTIN GIKKVLKKHN DDFEMTSFWL 1550
SNTCRLLHCL KQYSGDEGFM TQNTAKQNEH CLKNFDLTEY RQVLSDLSIQ 1600
IYQQLIKIAE GVLQPMIVSA MLENESIQGL SGVKPTGYRK RSSSMADGDN 1650
SYCLEAIIRQ MNAFHTVMCD QGLDPEIILQ VFKQLFYMIN AVTLNNLLLR 1700
KDVCSWSTGM QLRYNISQLE EWLRGRNLHQ SGAVQTMEPL IQAAQLLQLK 1750
KKTQEDAEAI CSLCTSLSTQ QIVKILNLYT PLNEFEERVT VAFIRTIQAQ 1800
LQERNDPQQL LLDAKHMFPV LFPFNPSSLT MDSIHIPACL NLEFLNEV 1848
Length:1,848
Mass (Da):213,672
Last modified:May 18, 2010 - v3
Checksum:i4EB8FA02F6B38707
GO

Sequence cautioni

The sequence BAA86433.2 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti10 – 101C → G.
Corresponds to variant rs16951438 [ dbSNP | Ensembl ].
VAR_056182
Natural varianti108 – 1081V → G in DIAR2. 1 Publication
VAR_054993
Natural varianti126 – 1261T → A.2 Publications
Corresponds to variant rs1815930 [ dbSNP | Ensembl ].
VAR_063141
Natural varianti219 – 2191R → H in DIAR2. 1 Publication
VAR_054994
Natural varianti307 – 3071K → N.
Corresponds to variant rs17659179 [ dbSNP | Ensembl ].
VAR_056183
Natural varianti656 – 6561R → C in DIAR2. 1 Publication
VAR_054995
Natural varianti918 – 9181R → H.
Corresponds to variant rs2298624 [ dbSNP | Ensembl ].
VAR_056184
Natural varianti942 – 9421K → R.
Corresponds to variant rs2277716 [ dbSNP | Ensembl ].
VAR_056185
Natural varianti1055 – 10551L → LL.2 Publications
Corresponds to variant rs72530399 [ dbSNP | Ensembl ].
VAR_063142

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB032945 mRNA. Translation: BAA86433.2. Different initiation.
AB290160 mRNA. Translation: BAG06714.1.
AC090227 Genomic DNA. No translation available.
AC092705 Genomic DNA. No translation available.
AC105224 Genomic DNA. No translation available.
CCDSiCCDS42436.1.
RefSeqiNP_001073936.1. NM_001080467.2.
UniGeneiHs.720076.

Genome annotation databases

EnsembliENST00000285039; ENSP00000285039; ENSG00000167306.
GeneIDi4645.
KEGGihsa:4645.
UCSCiuc002leb.2. human.

Polymorphism databases

DMDMi296439293.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB032945 mRNA. Translation: BAA86433.2 . Different initiation.
AB290160 mRNA. Translation: BAG06714.1 .
AC090227 Genomic DNA. No translation available.
AC092705 Genomic DNA. No translation available.
AC105224 Genomic DNA. No translation available.
CCDSi CCDS42436.1.
RefSeqi NP_001073936.1. NM_001080467.2.
UniGenei Hs.720076.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4J5M X-ray 2.07 A 1453-1848 [» ]
4LNZ X-ray 3.11 A 1460-1848 [» ]
4LWZ X-ray 2.55 B/D 1456-1848 [» ]
4LX0 X-ray 2.19 B/D 1456-1848 [» ]
ProteinModelPortali Q9ULV0.
SMRi Q9ULV0. Positions 5-816, 858-898, 1456-1848.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 110729. 10 interactions.
IntActi Q9ULV0. 4 interactions.
MINTi MINT-1209283.
STRINGi 9606.ENSP00000285039.

PTM databases

PhosphoSitei Q9ULV0.

Polymorphism databases

DMDMi 296439293.

Proteomic databases

MaxQBi Q9ULV0.
PaxDbi Q9ULV0.
PRIDEi Q9ULV0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000285039 ; ENSP00000285039 ; ENSG00000167306 .
GeneIDi 4645.
KEGGi hsa:4645.
UCSCi uc002leb.2. human.

Organism-specific databases

CTDi 4645.
GeneCardsi GC18M047349.
H-InvDB HIX0014446.
HGNCi HGNC:7603. MYO5B.
HPAi HPA040593.
HPA040902.
MIMi 251850. phenotype.
606540. gene.
neXtProti NX_Q9ULV0.
Orphaneti 2290. Microvillous inclusion disease.
PharmGKBi PA31408.
HUGEi Search...
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG5022.
HOGENOMi HOG000171839.
HOVERGENi HBG052556.
InParanoidi Q9ULV0.
KOi K10357.
OMAi QTMEPLI.
OrthoDBi EOG7PK8XT.
PhylomeDBi Q9ULV0.
TreeFami TF328771.

Enzyme and pathway databases

Reactomei REACT_24023. Regulation of water balance by renal Aquaporins.

Miscellaneous databases

ChiTaRSi MYO5B. human.
GeneWikii MYO5B.
GenomeRNAii 4645.
NextBioi 17900.
PROi Q9ULV0.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q9ULV0.
Bgeei Q9ULV0.
CleanExi HS_MYO5B.
Genevestigatori Q9ULV0.

Family and domain databases

InterProi IPR018444. Dil_domain.
IPR002710. Dilute.
IPR000048. IQ_motif_EF-hand-BS.
IPR001609. Myosin_head_motor_dom.
IPR027417. P-loop_NTPase.
[Graphical view ]
Pfami PF01843. DIL. 1 hit.
PF00612. IQ. 6 hits.
PF00063. Myosin_head. 1 hit.
[Graphical view ]
PRINTSi PR00193. MYOSINHEAVY.
SMARTi SM00015. IQ. 6 hits.
SM00242. MYSc. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 2 hits.
PROSITEi PS51126. DILUTE. 1 hit.
PS50096. IQ. 6 hits.
PS51456. MYOSIN_MOTOR. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain."
    Hirosawa M., Nagase T., Ishikawa K., Kikuno R., Nomura N., Ohara O.
    DNA Res. 6:329-336(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANTS ALA-126 AND LEU-1055 INS.
    Tissue: Brain.
  2. Ohara O., Nagase T., Yamakawa H., Kikuno R.
    Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: SEQUENCE REVISION TO N-TERMINUS AND 918.
  3. "Multiplex amplification and cloning of 5'-ends of cDNA by ligase-free recombination: preparation of full-length cDNA clones encoding motor proteins."
    Yamakawa H., Kikuno R.F., Nagase T., Ohara O.
    Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANTS ALA-126 AND LEU-1055 INS.
    Tissue: Brain.
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. Cited for: INTERACTION WITH RAB11FIP2.
  6. "CART: an Hrs/actinin-4/BERP/myosin V protein complex required for efficient receptor recycling."
    Yan Q., Sun W., Kujala P., Lotfi Y., Vida T.A., Bean A.J.
    Mol. Biol. Cell 16:2470-2482(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION IN THE CART COMPLEX.
  7. "Myosin Vb is required for trafficking of the cystic fibrosis transmembrane conductance regulator in Rab11a-specific apical recycling endosomes in polarized human airway epithelial cells."
    Swiatecka-Urban A., Talebian L., Kanno E., Moreau-Marquis S., Coutermarsh B., Hansen K., Karlson K.H., Barnaby R., Cheney R.E., Langford G.M., Fukuda M., Stanton B.A.
    J. Biol. Chem. 282:23725-23736(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INTERACTION WITH RAB11A, IDENTIFICATION IN A COMPLEX WITH RAB11A AND CFTR.
  8. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  9. "Requirement of myosin Vb.Rab11a.Rab11-FIP2 complex in cholesterol-regulated translocation of NPC1L1 to the cell surface."
    Chu B.-B., Ge L., Xie C., Zhao Y., Miao H.-H., Wang J., Li B.-L., Song B.-L.
    J. Biol. Chem. 284:22481-22490(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INTERACTION WITH NPC1L1.
  10. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1446, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  11. "Rab GTPase-Myo5B complexes control membrane recycling and epithelial polarization."
    Roland J.T., Bryant D.M., Datta A., Itzen A., Mostov K.E., Goldenring J.R.
    Proc. Natl. Acad. Sci. U.S.A. 108:2789-2794(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INTERACTION WITH RAB11A AND RAB8A, MUTAGENESIS OF GLN-1300; TYR-1307; TYR-1714 AND GLN-1748.
  12. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  13. Cited for: VARIANTS DIAR2 GLY-108; HIS-219 AND CYS-656.

Entry informationi

Entry nameiMYO5B_HUMAN
AccessioniPrimary (citable) accession number: Q9ULV0
Secondary accession number(s): B0I1R3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: May 18, 2010
Last modified: September 3, 2014
This is version 134 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 18
    Human chromosome 18: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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