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Protein

Cell cycle progression protein 1

Gene

CCPG1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Acts as an assembly platform for Rho protein signaling complexes. Limits guanine nucleotide exchange activity of MCF2L toward RHOA, which results in an inhibition of both its transcriptional activation ability and its transforming activity. Does not inhibit activity of MCF2L toward CDC42, or activity of MCF2 toward either RHOA or CDC42 (By similarity). May be involved in cell cycle regulation.By similarity1 Publication

GO - Biological processi

  1. cell cycle Source: UniProtKB-KW
  2. positive regulation of cell cycle Source: UniProtKB
  3. positive regulation of cell proliferation Source: UniProtKB
Complete GO annotation...

Keywords - Biological processi

Cell cycle

Names & Taxonomyi

Protein namesi
Recommended name:
Cell cycle progression protein 1
Alternative name(s):
Cell cycle progression restoration protein 8
Gene namesi
Name:CCPG1
Synonyms:CCP8, CPR8, KIAA1254
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome 15

Organism-specific databases

HGNCiHGNC:24227. CCPG1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 217217CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei218 – 23821Helical; Signal-anchor for type II membrane proteinSequence AnalysisAdd
BLAST
Topological domaini239 – 757519LumenalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134967250.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 757757Cell cycle progression protein 1PRO_0000310538Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei186 – 1861Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ9ULG6.
PaxDbiQ9ULG6.
PRIDEiQ9ULG6.

PTM databases

PhosphoSiteiQ9ULG6.

Expressioni

Gene expression databases

BgeeiQ9ULG6.
CleanExiHS_CCPG1.
ExpressionAtlasiQ9ULG6. baseline and differential.
GenevestigatoriQ9ULG6.

Organism-specific databases

HPAiHPA026861.

Interactioni

Subunit structurei

Interacts with MCF2L. May interact with MCF2, ARHGEF1, BCR, VAV1 and FGD1, but not with TIAM1. Interacts with GTP-bound CDC42 and SRC (By similarity).By similarity

Protein-protein interaction databases

BioGridi114665. 15 interactions.
IntActiQ9ULG6. 1 interaction.
STRINGi9606.ENSP00000311656.

Structurei

3D structure databases

ProteinModelPortaliQ9ULG6.
SMRiQ9ULG6. Positions 276-314.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni1 – 308308Interaction with MCF2L and SRCBy similarityAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili248 – 27225Sequence AnalysisAdd
BLAST
Coiled coili306 – 450145Sequence AnalysisAdd
BLAST
Coiled coili504 – 53027Sequence AnalysisAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi176 – 1816Poly-Arg

Sequence similaritiesi

Belongs to the CCPG1 family.Curated

Keywords - Domaini

Coiled coil, Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG38815.
GeneTreeiENSGT00530000063862.
HOGENOMiHOG000013199.
HOVERGENiHBG097118.
InParanoidiQ9ULG6.
OMAiHHWKELD.
OrthoDBiEOG76T9R5.
PhylomeDBiQ9ULG6.
TreeFamiTF333202.

Sequences (5)i

Sequence statusi: Complete.

This entry describes 5 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q9ULG6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSENSSDSDS SCGWTVISHE GSDIEMLNSV TPTDSCEPAP ECSSLEQEEL
60 70 80 90 100
QALQIEQGES SQNGTVLMEE TAYPALEETS STIEAEEQKI PEDSIYIGTA
110 120 130 140 150
SDDSDIVTLE PPKLEEIGNQ EVVIVEEAQS SEDFNMGSSS SSQYTFCQPE
160 170 180 190 200
TVFSSQPSDD ESSSDETSNQ PSPAFRRRRA RKKTVSASES EDRLVAEQET
210 220 230 240 250
EPSKELSKRQ FSSGLNKCVI LALVIAISMG FGHFYGTIQI QKRQQLVRKI
260 270 280 290 300
HEDELNDMKD YLSQCQQEQE SFIDYKSLKE NLARCWTLTE AEKMSFETQK
310 320 330 340 350
TNLATENQYL RVSLEKEEKA LSSLQEELNK LREQIRILED KGTSTELVKE
360 370 380 390 400
NQKLKQHLEE EKQKKHSFLS QRETLLTEAK MLKRELERER LVTTALRGEL
410 420 430 440 450
QQLSGSQLHG KSDSPNVYTE KKEIAILRER LTELERKLTF EQQRSDLWER
460 470 480 490 500
LYVEAKDQNG KQGTDGKKKG GRGSHRAKNK SKETFLGSVK ETFDAMKNST
510 520 530 540 550
KEFVRHHKEK IKQAKEAVKE NLKKFSDSVK STFRHFKDTT KNIFDEKGNK
560 570 580 590 600
RFGATKEAAE KPRTVFSDYL HPQYKAPTEN HHNRGPTMQN DGRKEKPVHF
610 620 630 640 650
KEFRKNTNSK KCSPGHDCRE NSHSFRKACS GVFDCAQQES MSLFNTVVNP
660 670 680 690 700
IRMDEFRQII QRYMLKELDT FCHWNELDQF INKFFLNGVF IHDQKLFTDF
710 720 730 740 750
VNDVKDYLRN MKEYEVDNDG VFEKLDEYIY RHFFGHTFSP PYGPRSVYIK

PCHYSSL
Length:757
Mass (Da):87,340
Last modified:November 12, 2007 - v3
Checksum:iDDF496D4431A7976
GO
Isoform 2 (identifier: Q9ULG6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-144: Missing.
     145-151: TFCQPET → MSTFFLI

Note: No experimental confirmation available.

Show »
Length:613
Mass (Da):71,854
Checksum:i0114FEFFF8D22908
GO
Isoform 3 (identifier: Q9ULG6-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     312-694: Missing.
     745-757: RSVYIKPCHYSSL → SRPDKKQRMV...LGQLPFDPQY

Show »
Length:424
Mass (Da):48,569
Checksum:iB8A999B9C6722C32
GO
Isoform 4 (identifier: Q9ULG6-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     582-598: HNRGPTMQNDGRKEKPV → SRPYYAKRWKERKASSL
     599-757: Missing.

Show »
Length:598
Mass (Da):68,395
Checksum:i6307C36112F2E2F1
GO
Isoform 5 (identifier: Q9ULG6-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     745-757: RSVYIKPCHYSSL → SRPDKKQRMV...LGQLPFDPQY

Note: No experimental confirmation available.

Show »
Length:807
Mass (Da):93,488
Checksum:i0C87EB9BE5B8AFD0
GO

Sequence cautioni

Isoform 4 : The sequence AAB69314.1 differs from that shown. Reason: Frameshift at position 594. Curated
The sequence AAB69314.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence AAH15203.1 differs from that shown.Contaminating sequence. Potential poly-A sequence.Curated
The sequence AAH29398.1 differs from that shown.Contaminating sequence. Potential poly-A sequence.Curated
Isoform 4 : The sequence AAK14914.1 differs from that shown. Reason: Frameshift at position 594. Curated
The sequence BAA86568.2 differs from that shown. Reason: Erroneous initiation. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti196 – 1961A → G in BAA86568 (PubMed:10574462).Curated
Sequence conflicti270 – 2701E → G in BAB14042 (PubMed:14702039).Curated
Sequence conflicti483 – 4831E → G in AAH29398 (PubMed:15489334).Curated
Sequence conflicti483 – 4831E → G in AAB69314 (PubMed:9383053).Curated
Sequence conflicti553 – 5531G → N in AAB69314 (PubMed:9383053).Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti44 – 441S → P.
Corresponds to variant rs11555304 [ dbSNP | Ensembl ].
VAR_037063
Natural varianti161 – 1611E → V.1 Publication
Corresponds to variant rs17853336 [ dbSNP | Ensembl ].
VAR_037064
Natural varianti418 – 4181Y → H.
Corresponds to variant rs34958422 [ dbSNP | Ensembl ].
VAR_037065
Natural varianti436 – 4361R → L.1 Publication
Corresponds to variant rs17857026 [ dbSNP | Ensembl ].
VAR_037066
Natural varianti477 – 4771A → V.1 Publication
Corresponds to variant rs1063562 [ dbSNP | Ensembl ].
VAR_037067
Natural varianti517 – 5171A → D.1 Publication
Corresponds to variant rs1063563 [ dbSNP | Ensembl ].
VAR_037068
Natural varianti553 – 5531G → D.
Corresponds to variant rs1063565 [ dbSNP | Ensembl ].
VAR_037069
Natural varianti553 – 5531G → S.
Corresponds to variant rs1063564 [ dbSNP | Ensembl ].
VAR_037070
Natural varianti590 – 5901N → K.
Corresponds to variant rs1063566 [ dbSNP | Ensembl ].
VAR_037071
Natural varianti627 – 6271K → E.1 Publication
Corresponds to variant rs17853335 [ dbSNP | Ensembl ].
VAR_037072
Natural varianti646 – 6461T → I.1 Publication
Corresponds to variant rs17857027 [ dbSNP | Ensembl ].
VAR_037073
Natural varianti673 – 6731H → R.
Corresponds to variant rs1063567 [ dbSNP | Ensembl ].
VAR_037074

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 144144Missing in isoform 2. 1 PublicationVSP_029311Add
BLAST
Alternative sequencei145 – 1517TFCQPET → MSTFFLI in isoform 2. 1 PublicationVSP_029312
Alternative sequencei312 – 694383Missing in isoform 3. 1 PublicationVSP_029313Add
BLAST
Alternative sequencei582 – 59817HNRGP…KEKPV → SRPYYAKRWKERKASSL in isoform 4. 2 PublicationsVSP_029314Add
BLAST
Alternative sequencei599 – 757159Missing in isoform 4. 2 PublicationsVSP_029315Add
BLAST
Alternative sequencei745 – 75713RSVYI…HYSSL → SRPDKKQRMVNIENSRHRKQ EQKHLQPQPYKREGKWHKYG RTNGRQMANLEIELGQLPFD PQY in isoform 3 and isoform 5. 1 PublicationVSP_029316Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB033080 mRNA. Translation: BAA86568.2. Different initiation.
AF212228 mRNA. Translation: AAK14914.1. Frameshift.
AK022459 mRNA. Translation: BAB14042.1.
AK292795 mRNA. Translation: BAF85484.1.
AC013355 Genomic DNA. No translation available.
AC018926 Genomic DNA. No translation available.
CH471082 Genomic DNA. Translation: EAW77481.1.
BC015203 mRNA. Translation: AAH15203.1. Sequence problems.
BC029398 mRNA. Translation: AAH29398.1. Sequence problems.
BC034914 mRNA. Translation: AAH34914.1.
BC039871 mRNA. Translation: AAH39871.1.
AF011794 mRNA. Translation: AAB69314.1. Sequence problems.
CCDSiCCDS42039.1. [Q9ULG6-1]
CCDS55966.1. [Q9ULG6-5]
CCDS55967.1. [Q9ULG6-3]
RefSeqiNP_001191379.1. NM_001204450.1. [Q9ULG6-5]
NP_001191380.1. NM_001204451.1. [Q9ULG6-3]
NP_004739.3. NM_004748.4. [Q9ULG6-1]
NP_065790.2. NM_020739.3. [Q9ULG6-1]
UniGeneiHs.285051.

Genome annotation databases

EnsembliENST00000310958; ENSP00000311656; ENSG00000260916. [Q9ULG6-1]
ENST00000425574; ENSP00000415128; ENSG00000260916. [Q9ULG6-3]
ENST00000442196; ENSP00000403400; ENSG00000260916. [Q9ULG6-5]
ENST00000569205; ENSP00000454456; ENSG00000260916. [Q9ULG6-1]
GeneIDi9236.
KEGGihsa:9236.
UCSCiuc002acu.2. human. [Q9ULG6-2]
uc002acv.2. human. [Q9ULG6-1]
uc002acx.3. human. [Q9ULG6-3]
uc002acy.3. human.

Polymorphism databases

DMDMi160380597.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB033080 mRNA. Translation: BAA86568.2. Different initiation.
AF212228 mRNA. Translation: AAK14914.1. Frameshift.
AK022459 mRNA. Translation: BAB14042.1.
AK292795 mRNA. Translation: BAF85484.1.
AC013355 Genomic DNA. No translation available.
AC018926 Genomic DNA. No translation available.
CH471082 Genomic DNA. Translation: EAW77481.1.
BC015203 mRNA. Translation: AAH15203.1. Sequence problems.
BC029398 mRNA. Translation: AAH29398.1. Sequence problems.
BC034914 mRNA. Translation: AAH34914.1.
BC039871 mRNA. Translation: AAH39871.1.
AF011794 mRNA. Translation: AAB69314.1. Sequence problems.
CCDSiCCDS42039.1. [Q9ULG6-1]
CCDS55966.1. [Q9ULG6-5]
CCDS55967.1. [Q9ULG6-3]
RefSeqiNP_001191379.1. NM_001204450.1. [Q9ULG6-5]
NP_001191380.1. NM_001204451.1. [Q9ULG6-3]
NP_004739.3. NM_004748.4. [Q9ULG6-1]
NP_065790.2. NM_020739.3. [Q9ULG6-1]
UniGeneiHs.285051.

3D structure databases

ProteinModelPortaliQ9ULG6.
SMRiQ9ULG6. Positions 276-314.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi114665. 15 interactions.
IntActiQ9ULG6. 1 interaction.
STRINGi9606.ENSP00000311656.

PTM databases

PhosphoSiteiQ9ULG6.

Polymorphism databases

DMDMi160380597.

Proteomic databases

MaxQBiQ9ULG6.
PaxDbiQ9ULG6.
PRIDEiQ9ULG6.

Protocols and materials databases

DNASUi9236.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000310958; ENSP00000311656; ENSG00000260916. [Q9ULG6-1]
ENST00000425574; ENSP00000415128; ENSG00000260916. [Q9ULG6-3]
ENST00000442196; ENSP00000403400; ENSG00000260916. [Q9ULG6-5]
ENST00000569205; ENSP00000454456; ENSG00000260916. [Q9ULG6-1]
GeneIDi9236.
KEGGihsa:9236.
UCSCiuc002acu.2. human. [Q9ULG6-2]
uc002acv.2. human. [Q9ULG6-1]
uc002acx.3. human. [Q9ULG6-3]
uc002acy.3. human.

Organism-specific databases

CTDi9236.
GeneCardsiGC15M055647.
HGNCiHGNC:24227. CCPG1.
HPAiHPA026861.
MIMi611326. gene.
neXtProtiNX_Q9ULG6.
PharmGKBiPA134967250.
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiNOG38815.
GeneTreeiENSGT00530000063862.
HOGENOMiHOG000013199.
HOVERGENiHBG097118.
InParanoidiQ9ULG6.
OMAiHHWKELD.
OrthoDBiEOG76T9R5.
PhylomeDBiQ9ULG6.
TreeFamiTF333202.

Miscellaneous databases

ChiTaRSiCCPG1. human.
GenomeRNAii9236.
NextBioi34627.
PROiQ9ULG6.
SOURCEiSearch...

Gene expression databases

BgeeiQ9ULG6.
CleanExiHS_CCPG1.
ExpressionAtlasiQ9ULG6. baseline and differential.
GenevestigatoriQ9ULG6.

Family and domain databases

ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
    Nagase T., Ishikawa K., Kikuno R., Hirosawa M., Nomura N., Ohara O.
    DNA Res. 6:337-345(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Brain.
  2. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
    Nakajima D., Okazaki N., Yamakawa H., Kikuno R., Ohara O., Nagase T.
    DNA Res. 9:99-106(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: SEQUENCE REVISION.
  3. "A novel gene expressed in human liver non-tumor tissues."
    Li Y., Wu T., Xu S., Ren S., Chen Z., Han Z.
    Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4).
    Tissue: Liver.
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3 AND 5).
    Tissue: Mammary gland and Trachea.
  5. "Analysis of the DNA sequence and duplication history of human chromosome 15."
    Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N., Abouelleil A.
    , Arachchi H.M., Baradarani L., Birditt B., Bloom S., Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K., DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B., Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.
    Nature 440:671-675(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2), VARIANTS VAL-161; LEU-436; GLU-627 AND ILE-646.
    Tissue: Brain, Lymph, Placenta and Skin.
  8. "Human CPR (cell cycle progression restoration) genes impart a Far-phenotype on yeast cells."
    Edwards M.C., Liegeois N., Horecka J., DePinho R.A., Sprague G.F. Jr., Tyers M., Elledge S.J.
    Genetics 147:1063-1076(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 379-757 (ISOFORM 4), FUNCTION, VARIANTS VAL-477 AND ASP-517.
  9. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
    Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.
    J. Proteomics 96:253-262(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-186, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Liver.

Entry informationi

Entry nameiCCPG1_HUMAN
AccessioniPrimary (citable) accession number: Q9ULG6
Secondary accession number(s): A0PJH3
, A8K9T0, O14712, Q05DG4, Q5U5S7, Q8IYV8, Q9BY53, Q9HA17
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 12, 2007
Last sequence update: November 12, 2007
Last modified: March 31, 2015
This is version 95 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.