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Protein
Submitted name:

Pyruvate kinase M2

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. magnesium ion binding Source: InterPro
  2. potassium ion binding Source: InterPro
  3. pyruvate kinase activity Source: InterPro

GO - Biological processi

  1. glycolytic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Keywords - Ligandi

PyruvateImported

Names & Taxonomyi

Protein namesi
Submitted name:
Pyruvate kinase M2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PRIDEiQ9UKK4.

Expressioni

Gene expression databases

BgeeiQ9UKK4.
ExpressionAtlasiQ9UKK4. baseline and differential.

Interactioni

Structurei

3D structure databases

ProteinModelPortaliQ9UKK4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

Gene3Di3.40.1380.20. 1 hit.
InterProiIPR001697. Pyr_Knase.
IPR015794. Pyrv_Knase_a/b.
IPR015795. Pyrv_Knase_C.
[Graphical view]
PANTHERiPTHR11817. PTHR11817. 1 hit.
SUPFAMiSSF52935. SSF52935. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q9UKK4-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
IAREAEAAIY HLQLFEELRR LAPITSDPTE ATAVGAVEAS FKCCSGAIIV

LTKSGR
Length:56
Mass (Da):5,976
Last modified:May 1, 2000 - v1
Checksum:iA7AF3AA24B1730BF
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei56 – 561Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF157692 Genomic DNA. Translation: AAD47248.1.
UniGeneiHs.534770.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF157692 Genomic DNA. Translation: AAD47248.1.
UniGeneiHs.534770.

3D structure databases

ProteinModelPortaliQ9UKK4.
ModBaseiSearch...
MobiDBiSearch...

Chemistry

BindingDBiQ9UKK4.

Proteomic databases

PRIDEiQ9UKK4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Gene expression databases

BgeeiQ9UKK4.
ExpressionAtlasiQ9UKK4. baseline and differential.

Family and domain databases

Gene3Di3.40.1380.20. 1 hit.
InterProiIPR001697. Pyr_Knase.
IPR015794. Pyrv_Knase_a/b.
IPR015795. Pyrv_Knase_C.
[Graphical view]
PANTHERiPTHR11817. PTHR11817. 1 hit.
SUPFAMiSSF52935. SSF52935. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Polymorphism in the inter-subunit contact domain region of the pyruvate kinase M2 gene in a normal cell line."
    Bamezai R.N.K., Anitha M., Saha A.
    Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ9UKK4_HUMAN
AccessioniPrimary (citable) accession number: Q9UKK4
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: November 26, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.