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Q9UIR0

- BTNL2_HUMAN

UniProt

Q9UIR0 - BTNL2_HUMAN

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Protein

Butyrophilin-like protein 2

Gene

BTNL2

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli

Functioni

Negative regulator of T-cell proliferation.By similarity

Protein family/group databases

MEROPSiI43.001.

Names & Taxonomyi

Protein namesi
Recommended name:
Butyrophilin-like protein 2
Short name:
BTL-II
Gene namesi
Name:BTNL2
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 6, UP000005640: Unplaced

Organism-specific databases

HGNCiHGNC:1142. BTNL2.

Subcellular locationi

Membrane 1 Publication; Single-pass type II membrane protein 1 Publication
Note: Isoform 2 is present in the nuclear, vesicle and plasma membranes, isoform 3 is found in cytoplasmic vesicle structures and is not membrane bound.

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 66CytoplasmicSequence Analysis
Transmembranei7 – 2317Helical; Signal-anchor for type II membrane proteinSequence AnalysisAdd
BLAST
Topological domaini24 – 455432ExtracellularSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Involvement in diseasei

Sarcoidosis 2 (SS2) [MIM:612387]: An idiopathic, systemic, inflammatory disease characterized by the formation of immune granulomas in involved organs. Granulomas predominantly invade the lungs and the lymphatic system, but also skin, liver, spleen, eyes and other organs may be involved.
Note: Disease susceptibility is associated with variations affecting the gene represented in this entry. A nucleotide transition affecting a splice donor site results in the use of an alternative splice site and the production of isoform 3. Individuals expressing isoform 3 have a higher risk for sarcoidosis.

Organism-specific databases

MIMi612387. phenotype.
Orphaneti797. Sarcoidosis.
PharmGKBiPA25463.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 455455Butyrophilin-like protein 2PRO_0000014537Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi50 ↔ 124PROSITE-ProRule annotation
Disulfide bondi164 ↔ 218PROSITE-ProRule annotation
Glycosylationi210 – 2101N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi267 ↔ 341PROSITE-ProRule annotation
Glycosylationi427 – 4271N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ9UIR0.
PRIDEiQ9UIR0.

PTM databases

PhosphoSiteiQ9UIR0.

Expressioni

Tissue specificityi

Expressed in brain, heart, kidney, liver, pancreas, ovary, leukocyte, small intestine, testis and thymus.1 Publication

Inductioni

By proinflammatory cytokines such as TNF and IL1B/interleukin-1 beta.1 Publication

Gene expression databases

BgeeiQ9UIR0.
ExpressionAtlasiQ9UIR0. baseline.
GenevestigatoriQ9UIR0.

Organism-specific databases

HPAiHPA039844.

Interactioni

Protein-protein interaction databases

BioGridi121112. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliQ9UIR0.
SMRiQ9UIR0. Positions 29-236, 244-452.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini29 – 140112Ig-like V-type 1Add
BLAST
Domaini142 – 23493Ig-like V-type 2Add
BLAST
Domaini236 – 355120Ig-like V-type 3Add
BLAST

Sequence similaritiesi

Keywords - Domaini

Immunoglobulin domain, Repeat, Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG131805.
GeneTreeiENSGT00760000118933.
HOVERGENiHBG054868.
InParanoidiQ9UIR0.
OMAiHIRMERP.
PhylomeDBiQ9UIR0.
TreeFamiTF331083.

Family and domain databases

Gene3Di2.60.40.10. 4 hits.
InterProiIPR013162. CD80_C2-set.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF08205. C2-set_2. 2 hits.
PF07686. V-set. 2 hits.
[Graphical view]
SMARTiSM00409. IG. 2 hits.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 3 hits.
[Graphical view]

Sequences (6)i

Sequence statusi: Complete.

This entry describes 6 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q9UIR0-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MVDFPGYNLS GAVASFLFIL LTMKQSEDFR VIGPAHPILA GVGEDALLTC
60 70 80 90 100
QLLPKRTTMH VEVRWYRSEP STPVFVHRDG VEVTEMQMEE YRGWVEWIEN
110 120 130 140 150
GIAKGNVALK IHNIQPSDNG QYWCHFQDGN YCGETSLLLK VAGLGSAPSI
160 170 180 190 200
HMEGPGESGV QLVCTARGWF PEPQVYWEDI RGEKLLAVSE HRIQDKDGLF
210 220 230 240 250
YAEATLVVRN ASAESVSCLV HNPVLTEEKG SVISLPEKLQ TELASLKVNG
260 270 280 290 300
PSQPILVRVG EDIQLTCYLS PKANAQSMEV RWDRSHRYPA VHVYMDGDHV
310 320 330 340 350
AGEQMAEYRG RTVLVSDAID EGRLTLQILS ARPSDDGQYR CLFEKDDVYQ
360 370 380 390 400
EASLDLKVVS LGSSPLITVE GQEDGEMQPM CSSDGWFPQP HVPWRDMEGK
410 420 430 440 450
TIPSSSQALT QGSHGLFHVQ TLLRVTNISA VDVTCSISIP FLGEEKIATF

SLSGW
Length:455
Mass (Da):50,436
Last modified:May 1, 2000 - v1
Checksum:i4194025C7416F839
GO
Isoform 2 (identifier: Q9UIR0-2) [UniParc]FASTAAdd to Basket

Also known as: Long

The sequence of this isoform differs from the canonical sequence as follows:
     143-236: Missing.
     454-455: GW → ESRMTFLWKTLLVWGLLLAVAVGLPRKRS

Show »
Length:388
Mass (Da):43,373
Checksum:iC7398D15BAF5492D
GO
Isoform 3 (identifier: Q9UIR0-3) [UniParc]FASTAAdd to Basket

Also known as: Short

The sequence of this isoform differs from the canonical sequence as follows:
     143-236: Missing.
     360-364: SLGSS → WVLPH
     365-455: Missing.

Show »
Length:270
Mass (Da):30,568
Checksum:i284B8285EA865323
GO
Isoform 4 (identifier: Q9UIR0-4) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     28-237: Missing.

Note: No experimental confirmation available.Curated

Show »
Length:245
Mass (Da):27,086
Checksum:i0141DB697EF1DDD4
GO
Isoform 5 (identifier: Q9UIR0-5) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-277: Missing.

Note: No experimental confirmation available.Curated

Show »
Length:178
Mass (Da):19,831
Checksum:iBE380AD9588A90C6
GO
Isoform 6 (identifier: Q9UIR0-6) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     244-259: ASLKVNGPSQPILVRV → GKYEVLAHTCGGSLCP
     260-455: Missing.

Note: No experimental confirmation available.

Show »
Length:259
Mass (Da):28,660
Checksum:iBF7BA587B9FC4526
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti27 – 271Missing in AAV91023. (PubMed:15516930)Curated
Isoform 5 (identifier: Q9UIR0-5)
Sequence conflicti83 – 831S → G in AAI19669. (PubMed:15489334)Curated
Isoform 4 (identifier: Q9UIR0-4)
Sequence conflicti150 – 1501S → G in AAI27643. (PubMed:15489334)Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti94 – 941W → R.
Corresponds to variant rs28362682 [ dbSNP | Ensembl ].
VAR_033602
Natural varianti181 – 1811R → Q.
Corresponds to variant rs28362681 [ dbSNP | Ensembl ].
VAR_061307
Natural varianti188 – 1881V → M.
Corresponds to variant rs9461742 [ dbSNP | Ensembl ].
VAR_049837
Natural varianti196 – 1961K → E.1 Publication
Corresponds to variant rs2076523 [ dbSNP | Ensembl ].
VAR_021171
Natural varianti202 – 2021A → V.
Corresponds to variant rs28362680 [ dbSNP | Ensembl ].
VAR_061308
Natural varianti283 – 2831D → V.
Corresponds to variant rs34423804 [ dbSNP | Ensembl ].
VAR_033603
Natural varianti334 – 3341S → L.1 Publication
Corresponds to variant rs28362679 [ dbSNP | Ensembl ].
VAR_029128
Natural varianti352 – 3521A → T.
Corresponds to variant rs35037492 [ dbSNP | Ensembl ].
VAR_033604
Natural varianti360 – 3601S → G.
Corresponds to variant rs2076530 [ dbSNP | Ensembl ].
VAR_049838
Natural varianti379 – 3791P → L.
Corresponds to variant rs28362678 [ dbSNP | Ensembl ].
VAR_033605
Natural varianti380 – 3801M → I.
Corresponds to variant rs28362677 [ dbSNP | Ensembl ].
VAR_033606
Natural varianti393 – 3931P → Q.
Corresponds to variant rs41521946 [ dbSNP | Ensembl ].
VAR_033607

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 277277Missing in isoform 5. 1 PublicationVSP_027184Add
BLAST
Alternative sequencei28 – 237210Missing in isoform 4. 1 PublicationVSP_027185Add
BLAST
Alternative sequencei143 – 23694Missing in isoform 2 and isoform 3. CuratedVSP_027186Add
BLAST
Alternative sequencei244 – 25916ASLKV…ILVRV → GKYEVLAHTCGGSLCP in isoform 6. CuratedVSP_027187Add
BLAST
Alternative sequencei260 – 455196Missing in isoform 6. CuratedVSP_027188Add
BLAST
Alternative sequencei360 – 3645SLGSS → WVLPH in isoform 3. CuratedVSP_027189
Alternative sequencei365 – 45591Missing in isoform 3. CuratedVSP_027190Add
BLAST
Alternative sequencei454 – 4552GW → ESRMTFLWKTLLVWGLLLAV AVGLPRKRS in isoform 2. CuratedVSP_027191

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF186593
, AF186588, AF186589, AF186591, AF186592, AF186590 Genomic DNA. Translation: AAF05530.1.
AY881999 Genomic DNA. Translation: AAX35330.1.
AY881999 Genomic DNA. Translation: AAX35331.1.
AL034394, Z84814 Genomic DNA. Translation: CAI42180.1.
Z84814, AL034394 Genomic DNA. Translation: CAC69895.2.
AL662796 Genomic DNA. Translation: CAI18265.2.
AL670296 Genomic DNA. Translation: CAI17569.2.
AL670296 Genomic DNA. Translation: CAI17570.2.
AL935032 Genomic DNA. Translation: CAI18474.2.
AL935032 Genomic DNA. Translation: CAI18475.2.
BX255945 Genomic DNA. Translation: CAI18727.2.
CR753634 Genomic DNA. Translation: CAQ08809.1.
CR759917 Genomic DNA. Translation: CAQ07562.1.
BC119668 mRNA. Translation: AAI19669.1.
BC127642 mRNA. Translation: AAI27643.1.
AY684332 mRNA. Translation: AAV91022.1.
AY684333 mRNA. Translation: AAV91023.1.
RefSeqiNP_062548.1. NM_019602.1. [Q9UIR0-1]
UniGeneiHs.534471.

Genome annotation databases

EnsembliENST00000374993; ENSP00000364132; ENSG00000204290. [Q9UIR0-1]
ENST00000544175; ENSP00000443364; ENSG00000204290. [Q9UIR0-5]
ENST00000548253; ENSP00000447733; ENSG00000224242.
ENST00000548717; ENSP00000449356; ENSG00000225412.
ENST00000548832; ENSP00000448852; ENSG00000229741. [Q9UIR0-4]
ENST00000549560; ENSP00000448550; ENSG00000226127. [Q9UIR0-5]
ENST00000549852; ENSP00000446915; ENSG00000225845.
ENST00000549943; ENSP00000449578; ENSG00000224770. [Q9UIR0-5]
ENST00000550327; ENSP00000447985; ENSG00000226127. [Q9UIR0-1]
ENST00000550531; ENSP00000448023; ENSG00000229597. [Q9UIR0-1]
ENST00000550698; ENSP00000447616; ENSG00000229597. [Q9UIR0-5]
ENST00000551095; ENSP00000449546; ENSG00000229741. [Q9UIR0-1]
ENST00000551669; ENSP00000446794; ENSG00000224242.
ENST00000551686; ENSP00000450139; ENSG00000225412.
ENST00000552479; ENSP00000449365; ENSG00000224770. [Q9UIR0-1]
ENST00000553032; ENSP00000447291; ENSG00000229741. [Q9UIR0-5]
GeneIDi56244.
KEGGihsa:56244.
UCSCiuc003obg.1. human. [Q9UIR0-1]
uc010jua.1. human. [Q9UIR0-4]

Polymorphism databases

DMDMi73921189.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF186593
, AF186588 , AF186589 , AF186591 , AF186592 , AF186590 Genomic DNA. Translation: AAF05530.1 .
AY881999 Genomic DNA. Translation: AAX35330.1 .
AY881999 Genomic DNA. Translation: AAX35331.1 .
AL034394 , Z84814 Genomic DNA. Translation: CAI42180.1 .
Z84814 , AL034394 Genomic DNA. Translation: CAC69895.2 .
AL662796 Genomic DNA. Translation: CAI18265.2 .
AL670296 Genomic DNA. Translation: CAI17569.2 .
AL670296 Genomic DNA. Translation: CAI17570.2 .
AL935032 Genomic DNA. Translation: CAI18474.2 .
AL935032 Genomic DNA. Translation: CAI18475.2 .
BX255945 Genomic DNA. Translation: CAI18727.2 .
CR753634 Genomic DNA. Translation: CAQ08809.1 .
CR759917 Genomic DNA. Translation: CAQ07562.1 .
BC119668 mRNA. Translation: AAI19669.1 .
BC127642 mRNA. Translation: AAI27643.1 .
AY684332 mRNA. Translation: AAV91022.1 .
AY684333 mRNA. Translation: AAV91023.1 .
RefSeqi NP_062548.1. NM_019602.1. [Q9UIR0-1 ]
UniGenei Hs.534471.

3D structure databases

ProteinModelPortali Q9UIR0.
SMRi Q9UIR0. Positions 29-236, 244-452.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 121112. 1 interaction.

Protein family/group databases

MEROPSi I43.001.

PTM databases

PhosphoSitei Q9UIR0.

Polymorphism databases

DMDMi 73921189.

Proteomic databases

PaxDbi Q9UIR0.
PRIDEi Q9UIR0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000374993 ; ENSP00000364132 ; ENSG00000204290 . [Q9UIR0-1 ]
ENST00000544175 ; ENSP00000443364 ; ENSG00000204290 . [Q9UIR0-5 ]
ENST00000548253 ; ENSP00000447733 ; ENSG00000224242 .
ENST00000548717 ; ENSP00000449356 ; ENSG00000225412 .
ENST00000548832 ; ENSP00000448852 ; ENSG00000229741 . [Q9UIR0-4 ]
ENST00000549560 ; ENSP00000448550 ; ENSG00000226127 . [Q9UIR0-5 ]
ENST00000549852 ; ENSP00000446915 ; ENSG00000225845 .
ENST00000549943 ; ENSP00000449578 ; ENSG00000224770 . [Q9UIR0-5 ]
ENST00000550327 ; ENSP00000447985 ; ENSG00000226127 . [Q9UIR0-1 ]
ENST00000550531 ; ENSP00000448023 ; ENSG00000229597 . [Q9UIR0-1 ]
ENST00000550698 ; ENSP00000447616 ; ENSG00000229597 . [Q9UIR0-5 ]
ENST00000551095 ; ENSP00000449546 ; ENSG00000229741 . [Q9UIR0-1 ]
ENST00000551669 ; ENSP00000446794 ; ENSG00000224242 .
ENST00000551686 ; ENSP00000450139 ; ENSG00000225412 .
ENST00000552479 ; ENSP00000449365 ; ENSG00000224770 . [Q9UIR0-1 ]
ENST00000553032 ; ENSP00000447291 ; ENSG00000229741 . [Q9UIR0-5 ]
GeneIDi 56244.
KEGGi hsa:56244.
UCSCi uc003obg.1. human. [Q9UIR0-1 ]
uc010jua.1. human. [Q9UIR0-4 ]

Organism-specific databases

CTDi 56244.
GeneCardsi GC06M032359.
GC06Mi32371.
GC06Mj32308.
GC06Mk32336.
GC06Ml32400.
GC06Mn32318.
GC06Mo32367.
H-InvDB HIX0164795.
HIX0165959.
HIX0166164.
HIX0166450.
HIX0166717.
HIX0166977.
HIX0167211.
HIX0167458.
HGNCi HGNC:1142. BTNL2.
HPAi HPA039844.
MIMi 606000. gene.
612387. phenotype.
neXtProti NX_Q9UIR0.
Orphaneti 797. Sarcoidosis.
PharmGKBi PA25463.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG131805.
GeneTreei ENSGT00760000118933.
HOVERGENi HBG054868.
InParanoidi Q9UIR0.
OMAi HIRMERP.
PhylomeDBi Q9UIR0.
TreeFami TF331083.

Miscellaneous databases

GeneWikii BTNL2.
GenomeRNAii 56244.
NextBioi 61864.
PROi Q9UIR0.
SOURCEi Search...

Gene expression databases

Bgeei Q9UIR0.
ExpressionAtlasi Q9UIR0. baseline.
Genevestigatori Q9UIR0.

Family and domain databases

Gene3Di 2.60.40.10. 4 hits.
InterProi IPR013162. CD80_C2-set.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
[Graphical view ]
Pfami PF08205. C2-set_2. 2 hits.
PF07686. V-set. 2 hits.
[Graphical view ]
SMARTi SM00409. IG. 2 hits.
[Graphical view ]
PROSITEi PS50835. IG_LIKE. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "BTL-II: a polymorphic locus with homology to the butyrophilin gene family, located at the border of the major histocompatibility complex class II and class III regions in human and mouse."
    Stammers M., Rowen L., Rhodes D., Trowsdale J., Beck S.
    Immunogenetics 51:373-382(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], SUBCELLULAR LOCATION, ALTERNATIVE SPLICING, TISSUE SPECIFICITY, INDUCTION, INVOLVEMENT IN SUSCEPTIBILITY TO SARCOIDOSIS TYPE 2.
  3. "The DNA sequence and analysis of human chromosome 6."
    Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D.
    , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P., Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V., Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J., Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E., Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A., Frankland J., French L., Garner P., Garnett J., Ghori M.J., Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M., Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S., Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R., Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E., Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A., Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K., McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T., Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R., Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W., Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M., Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L., Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J., Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L., Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W., Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.
    Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], VARIANTS GLU-196 AND LEU-334.
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 4 AND 5).
  5. "Widespread occurrence of alternative splicing at NAGNAG acceptors contributes to proteome plasticity."
    Hiller M., Huse K., Szafranski K., Jahn N., Hampe J., Schreiber S., Backofen R., Platzer M.
    Nat. Genet. 36:1255-1257(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-109 (ISOFORMS 1/2/3/6).

Entry informationi

Entry nameiBTNL2_HUMAN
AccessioniPrimary (citable) accession number: Q9UIR0
Secondary accession number(s): A0PJV5
, B0UYW9, B0V0N6, O98261, Q08E96, Q58R22, Q58R23, Q5JYF9, Q5MP42, Q5MP43, Q5RIF8, Q5SP08, Q5SP09, Q5SRW3, Q5SRW4, Q5SU36, Q95HK0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: May 1, 2000
Last modified: November 26, 2014
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3