Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Tumor necrosis factor receptor 2

Gene

TNFR2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. tumor necrosis factor-activated receptor activity Source: Ensembl

GO - Biological processi

  1. aging Source: Ensembl
  2. cellular response to growth factor stimulus Source: Ensembl
  3. extrinsic apoptotic signaling pathway Source: Ensembl
  4. immune response Source: Ensembl
  5. inflammatory response Source: Ensembl
  6. intrinsic apoptotic signaling pathway in response to DNA damage Source: Ensembl
  7. negative regulation of inflammatory response Source: Ensembl
  8. response to lipopolysaccharide Source: Ensembl
  9. RNA destabilization Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Tumor necrosis factor receptor 2Imported
Gene namesi
Name:TNFR2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. membrane raft Source: Ensembl
  2. neuronal cell body Source: Ensembl
  3. nucleus Source: Ensembl
  4. perinuclear region of cytoplasm Source: Ensembl
  5. varicosity Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ9UIG9.
ExpressionAtlasiQ9UIG9. baseline and differential.

Family & Domainsi

Family and domain databases

InterProiIPR020411. TNFR_1B.
IPR001507. ZP_dom.
[Graphical view]
PRINTSiPR01919. TNFACTORR1B.
PROSITEiPS51034. ZP_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9UIG9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
SSPGGHGTQV NVTCIVNVCS SSDHSSQCSS QASSTMGDTD SSPSESPKDE
60 70 80 90
QVPFSKEECA FRSQLETPET LLGSTEEKPL PLGVPDAGMK PS
Length:92
Mass (Da):9,530
Last modified:April 30, 2000 - v1
Checksum:i89BEDE40B7CC4FE1
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB030952 Genomic DNA. Translation: BAA89055.1.
UniGeneiHs.256278.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB030952 Genomic DNA. Translation: BAA89055.1.
UniGeneiHs.256278.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

ChiTaRSiTNFRSF1B. human.

Gene expression databases

BgeeiQ9UIG9.
ExpressionAtlasiQ9UIG9. baseline and differential.

Family and domain databases

InterProiIPR020411. TNFR_1B.
IPR001507. ZP_dom.
[Graphical view]
PRINTSiPR01919. TNFACTORR1B.
PROSITEiPS51034. ZP_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "New single nucleotide polymorphisms in the coding region of human TNFR2: association with systemic lupus erythematosus."
    Tsuchiya N., Komata T., Matsushita M., Ohashi J., Tokunaga K.
    Genes Immun. 1:501-503(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ9UIG9_HUMAN
AccessioniPrimary (citable) accession number: Q9UIG9
Entry historyi
Integrated into UniProtKB/TrEMBL: April 30, 2000
Last sequence update: April 30, 2000
Last modified: November 25, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.