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Q9UIG9

- Q9UIG9_HUMAN

UniProt

Q9UIG9 - Q9UIG9_HUMAN

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Protein
Submitted name:

Tumor necrosis factor receptor 2

Gene

TNFR2

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. tumor necrosis factor-activated receptor activity Source: Ensembl

GO - Biological processi

  1. aging Source: Ensembl
  2. cellular response to growth factor stimulus Source: Ensembl
  3. extrinsic apoptotic signaling pathway Source: Ensembl
  4. immune response Source: Ensembl
  5. inflammatory response Source: Ensembl
  6. intrinsic apoptotic signaling pathway in response to DNA damage Source: Ensembl
  7. negative regulation of inflammatory response Source: Ensembl
  8. response to lipopolysaccharide Source: Ensembl
  9. RNA destabilization Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Tumor necrosis factor receptor 2Imported
Gene namesi
Name:TNFR2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. membrane raft Source: Ensembl
  2. neuronal cell body Source: Ensembl
  3. nucleus Source: Ensembl
  4. perinuclear region of cytoplasm Source: Ensembl
  5. varicosity Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ9UIG9.
ExpressionAtlasiQ9UIG9. baseline and differential.

Family & Domainsi

Family and domain databases

InterProiIPR020411. TNFR_1B.
IPR001507. ZP_dom.
[Graphical view]
PRINTSiPR01919. TNFACTORR1B.
PROSITEiPS51034. ZP_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9UIG9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
SSPGGHGTQV NVTCIVNVCS SSDHSSQCSS QASSTMGDTD SSPSESPKDE
60 70 80 90
QVPFSKEECA FRSQLETPET LLGSTEEKPL PLGVPDAGMK PS
Length:92
Mass (Da):9,530
Last modified:May 1, 2000 - v1
Checksum:i89BEDE40B7CC4FE1
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB030952 Genomic DNA. Translation: BAA89055.1.
UniGeneiHs.256278.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB030952 Genomic DNA. Translation: BAA89055.1 .
UniGenei Hs.256278.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Gene expression databases

Bgeei Q9UIG9.
ExpressionAtlasi Q9UIG9. baseline and differential.

Family and domain databases

InterProi IPR020411. TNFR_1B.
IPR001507. ZP_dom.
[Graphical view ]
PRINTSi PR01919. TNFACTORR1B.
PROSITEi PS51034. ZP_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "New single nucleotide polymorphisms in the coding region of human TNFR2: association with systemic lupus erythematosus."
    Tsuchiya N., Komata T., Matsushita M., Ohashi J., Tokunaga K.
    Genes Immun. 1:501-503(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ9UIG9_HUMAN
AccessioniPrimary (citable) accession number: Q9UIG9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: October 29, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.