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Q9UIG9

- Q9UIG9_HUMAN

UniProt

Q9UIG9 - Q9UIG9_HUMAN

Protein
Submitted name:

Tumor necrosis factor receptor 2

Gene

TNFR2

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. tumor necrosis factor-activated receptor activity Source: Ensembl

    GO - Biological processi

    1. aging Source: Ensembl
    2. cellular response to growth factor stimulus Source: Ensembl
    3. immune response Source: Ensembl
    4. inflammatory response Source: Ensembl
    5. intrinsic apoptotic signaling pathway in response to DNA damage Source: Ensembl
    6. negative regulation of inflammatory response Source: Ensembl
    7. response to lipopolysaccharide Source: Ensembl
    8. RNA destabilization Source: Ensembl

    Keywords - Molecular functioni

    ReceptorImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Tumor necrosis factor receptor 2Imported
    Gene namesi
    Name:TNFR2Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. membrane raft Source: Ensembl
    2. neuronal cell body Source: Ensembl
    3. nucleus Source: Ensembl
    4. perinuclear region of cytoplasm Source: Ensembl
    5. varicosity Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiQ9UIG9.
    BgeeiQ9UIG9.

    Family & Domainsi

    Family and domain databases

    InterProiIPR020411. TNFR_1B.
    IPR001507. ZP_dom.
    [Graphical view]
    PRINTSiPR01919. TNFACTORR1B.
    PROSITEiPS51034. ZP_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q9UIG9-1 [UniParc]FASTAAdd to Basket

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    SSPGGHGTQV NVTCIVNVCS SSDHSSQCSS QASSTMGDTD SSPSESPKDE   50
    QVPFSKEECA FRSQLETPET LLGSTEEKPL PLGVPDAGMK PS 92
    Length:92
    Mass (Da):9,530
    Last modified:May 1, 2000 - v1
    Checksum:i89BEDE40B7CC4FE1
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB030952 Genomic DNA. Translation: BAA89055.1.
    UniGeneiHs.256278.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB030952 Genomic DNA. Translation: BAA89055.1 .
    UniGenei Hs.256278.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Gene expression databases

    ArrayExpressi Q9UIG9.
    Bgeei Q9UIG9.

    Family and domain databases

    InterProi IPR020411. TNFR_1B.
    IPR001507. ZP_dom.
    [Graphical view ]
    PRINTSi PR01919. TNFACTORR1B.
    PROSITEi PS51034. ZP_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "New single nucleotide polymorphisms in the coding region of human TNFR2: association with systemic lupus erythematosus."
      Tsuchiya N., Komata T., Matsushita M., Ohashi J., Tokunaga K.
      Genes Immun. 1:501-503(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ9UIG9_HUMAN
    AccessioniPrimary (citable) accession number: Q9UIG9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 1, 2000
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.