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Q9UIG9

- Q9UIG9_HUMAN

UniProt

Q9UIG9 - Q9UIG9_HUMAN

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Protein
Submitted name: Tumor necrosis factor receptor 2
Gene
TNFR2
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. tumor necrosis factor-activated receptor activity Source: Ensembl
Complete GO annotation...

GO - Biological processi

  1. RNA destabilization Source: Ensembl
  2. aging Source: Ensembl
  3. cellular response to growth factor stimulus Source: Ensembl
  4. immune response Source: Ensembl
  5. inflammatory response Source: Ensembl
  6. intrinsic apoptotic signaling pathway in response to DNA damage Source: Ensembl
  7. negative regulation of inflammatory response Source: Ensembl
  8. response to lipopolysaccharide Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Tumor necrosis factor receptor 2Imported
Gene namesi
Name:TNFR2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. membrane raft Source: Ensembl
  2. neuronal cell body Source: Ensembl
  3. nucleus Source: Ensembl
  4. perinuclear region of cytoplasm Source: Ensembl
  5. varicosity Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiQ9UIG9.
BgeeiQ9UIG9.

Family & Domainsi

Family and domain databases

InterProiIPR020411. TNFR_1B.
IPR001507. ZP_dom.
[Graphical view]
PRINTSiPR01919. TNFACTORR1B.
PROSITEiPS51034. ZP_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9UIG9-1 [UniParc]FASTAAdd to Basket

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SSPGGHGTQV NVTCIVNVCS SSDHSSQCSS QASSTMGDTD SSPSESPKDE   50
QVPFSKEECA FRSQLETPET LLGSTEEKPL PLGVPDAGMK PS 92
Length:92
Mass (Da):9,530
Last modified:May 1, 2000 - v1
Checksum:i89BEDE40B7CC4FE1
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB030952 Genomic DNA. Translation: BAA89055.1.
UniGeneiHs.256278.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB030952 Genomic DNA. Translation: BAA89055.1 .
UniGenei Hs.256278.

3D structure databases

ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Gene expression databases

ArrayExpressi Q9UIG9.
Bgeei Q9UIG9.

Family and domain databases

InterProi IPR020411. TNFR_1B.
IPR001507. ZP_dom.
[Graphical view ]
PRINTSi PR01919. TNFACTORR1B.
PROSITEi PS51034. ZP_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "New single nucleotide polymorphisms in the coding region of human TNFR2: association with systemic lupus erythematosus."
    Tsuchiya N., Komata T., Matsushita M., Ohashi J., Tokunaga K.
    Genes Immun. 1:501-503(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ9UIG9_HUMAN
AccessioniPrimary (citable) accession number: Q9UIG9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: July 9, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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