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Q9UIG8

- SO3A1_HUMAN

UniProt

Q9UIG8 - SO3A1_HUMAN

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Protein
Solute carrier organic anion transporter family member 3A1
Gene
SLCO3A1, OATP3A1, OATPD, SLC21A11
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Mediates the Na+-independent transport of organic anions such as estrone-3-sulfate (1 Publication). Mediates transport of prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II, BQ-123 and vasopressin, but not DPDPE (a derivative of enkephalin lacking an N-terminal tyrosine residue), estrone-3-sulfate, taurocholate, digoxin nor DHEAS (1 Publication).1 Publication

Kineticsi

  1. KM=101 nM for PGE1 (isoform 1)1 Publication
  2. KM=218 nM for PGE1 (isoform 2)
  3. KM=219 nM for PGE2 (isoform 1)
  4. KM=371 nM for PGE2 (isoform 2)

GO - Molecular functioni

  1. transporter activity Source: InterPro

GO - Biological processi

  1. sodium-independent organic anion transport Source: Reactome
  2. transmembrane transport Source: Reactome
Complete GO annotation...

Keywords - Biological processi

Ion transport, Transport

Enzyme and pathway databases

ReactomeiREACT_23988. Transport of organic anions.

Protein family/group databases

TCDBi2.A.60.1.18. the organo anion transporter (oat) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Solute carrier organic anion transporter family member 3A1
Short name:
OATP3A1
Alternative name(s):
Organic anion transporter polypeptide-related protein 3
Short name:
OATP-RP3
Short name:
OATPRP3
Organic anion-transporting polypeptide D
Short name:
OATP-D
PGE1 transporter
Sodium-independent organic anion transporter D
Solute carrier family 21 member 11
Gene namesi
Name:SLCO3A1
Synonyms:OATP3A1, OATPD, SLC21A11
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 15

Organism-specific databases

HGNCiHGNC:10952. SLCO3A1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 4040Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei41 – 6020Helical; Name=1; Reviewed prediction
Add
BLAST
Topological domaini61 – 7919Extracellular Reviewed prediction
Add
BLAST
Transmembranei80 – 10021Helical; Name=2; Reviewed prediction
Add
BLAST
Topological domaini101 – 1066Cytoplasmic Reviewed prediction
Transmembranei107 – 13125Helical; Name=3; Reviewed prediction
Add
BLAST
Topological domaini132 – 17443Extracellular Reviewed prediction
Add
BLAST
Transmembranei175 – 20329Helical; Name=4; Reviewed prediction
Add
BLAST
Topological domaini204 – 22219Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei223 – 24321Helical; Name=5; Reviewed prediction
Add
BLAST
Topological domaini244 – 26118Extracellular Reviewed prediction
Add
BLAST
Transmembranei262 – 28625Helical; Name=6; Reviewed prediction
Add
BLAST
Topological domaini287 – 34458Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei345 – 36622Helical; Name=7; Reviewed prediction
Add
BLAST
Topological domaini367 – 38620Extracellular Reviewed prediction
Add
BLAST
Transmembranei387 – 41024Helical; Name=8; Reviewed prediction
Add
BLAST
Topological domaini411 – 4144Cytoplasmic Reviewed prediction
Transmembranei415 – 43824Helical; Name=9; Reviewed prediction
Add
BLAST
Topological domaini439 – 539101Extracellular Reviewed prediction
Add
BLAST
Transmembranei540 – 56223Helical; Name=10; Reviewed prediction
Add
BLAST
Topological domaini563 – 5719Cytoplasmic Reviewed prediction
Transmembranei572 – 59726Helical; Name=11; Reviewed prediction
Add
BLAST
Topological domaini598 – 63033Extracellular Reviewed prediction
Add
BLAST
Transmembranei631 – 64818Helical; Name=12; Reviewed prediction
Add
BLAST
Topological domaini649 – 70557Cytoplasmic Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: Reactome
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA35837.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 710710Solute carrier organic anion transporter family member 3A1
PRO_0000191064Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi153 – 1531N-linked (GlcNAc...) Reviewed prediction
Glycosylationi169 – 1691N-linked (GlcNAc...) Reviewed prediction
Glycosylationi381 – 3811N-linked (GlcNAc...) Reviewed prediction
Glycosylationi457 – 4571N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi471 ↔ 497 By similarity
Disulfide bondi475 ↔ 486 By similarity
Disulfide bondi477 ↔ 501 By similarity
Glycosylationi502 – 5021N-linked (GlcNAc...) Reviewed prediction
Glycosylationi505 – 5051N-linked (GlcNAc...) Reviewed prediction
Glycosylationi519 – 5191N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

MaxQBiQ9UIG8.
PaxDbiQ9UIG8.
PRIDEiQ9UIG8.

PTM databases

PhosphoSiteiQ9UIG8.

Expressioni

Tissue specificityi

Ubiquitous. Highly expressed in spleen and leukocytes. Generally the expression of isoform 1 is higher than that of isoform 2. Isoform 2 is particularly abundant in testis and brain. In testis, isoform 1 is detected in spermatogonia at different stages and absent from Sertoli cells, while isoform 2 is present in both (at protein level). Expressed in the choroid plexus epithelium, isoform 1 being localized at the basolateral membrane and isoform 2 at the apical one, as well as in the subapical intracellular vesicular compartments. Differential expression of both isoforms is also observed in other brain region: isoform 1 is very abundant in the gray matter of the frontal cortex, but is not associated with neuronal cell bodies. Not detected in the white matter. In contrast, isoform 2 is associated with neuronal bodies and axons in both the gray and the white matters of the frontal cortex.1 Publication

Gene expression databases

ArrayExpressiQ9UIG8.
BgeeiQ9UIG8.
CleanExiHS_SLCO3A1.
GenevestigatoriQ9UIG8.

Interactioni

Protein-protein interaction databases

IntActiQ9UIG8. 1 interaction.
STRINGi9606.ENSP00000320634.

Structurei

3D structure databases

ProteinModelPortaliQ9UIG8.
SMRiQ9UIG8. Positions 474-499.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini465 – 51349Kazal-like
Add
BLAST

Sequence similaritiesi

Contains 1 Kazal-like domain.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG320775.
HOVERGENiHBG098539.
InParanoidiQ9UIG8.
KOiK14353.
OMAiPANQTHR.
OrthoDBiEOG7GQXV6.
PhylomeDBiQ9UIG8.
TreeFamiTF317540.

Family and domain databases

InterProiIPR002350. Kazal_dom.
IPR016196. MFS_dom_general_subst_transpt.
IPR004156. OA_transporter.
[Graphical view]
PANTHERiPTHR11388. PTHR11388. 1 hit.
PfamiPF07648. Kazal_2. 1 hit.
PF03137. OATP. 1 hit.
[Graphical view]
SMARTiSM00280. KAZAL. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 4 hits.
TIGRFAMsiTIGR00805. oat. 1 hit.
PROSITEiPS51465. KAZAL_2. 1 hit.
[Graphical view]

Sequences (4)i

Sequence statusi: Complete.

This entry describes 4 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q9UIG8-1) [UniParc]FASTAAdd to Basket

Also known as: OATP3A1-v1

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MQGKKPGGSS GGGRSGELQG DEAQRNKKKK KKVSCFSNIK IFLVSECALM    50
LAQGTVGAYL VSVLTTLERR FNLQSADVGV IASSFEIGNL ALILFVSYFG 100
ARGHRPRLIG CGGIVMALGA LLSALPEFLT HQYKYEAGEI RWGAEGRDVC 150
AANGSGGDEG PDPDLICRNR TATNMMYLLL IGAQVLLGIG ATPVQPLGVS 200
YIDDHVRRKD SSLYIGILFT MLVFGPACGF ILGSFCTKIY VDAVFIDTSN 250
LDITPDDPRW IGAWWGGFLL CGALLFFSSL LMFGFPQSLP PHSEPAMESE 300
QAMLSEREYE RPKPSNGVLR HPLEPDSSAS CFQQLRVIPK VTKHLLSNPV 350
FTCIILAACM EIAVVAGFAA FLGKYLEQQF NLTTSSANQL LGMTAIPCAC 400
LGIFLGGLLV KKLSLSALGA IRMAMLVNLV STACYVSFLF LGCDTGPVAG 450
VTVPYGNSTA PGSALDPYSP CNNNCECQTD SFTPVCGADG ITYLSACFAG 500
CNSTNLTGCA CLTTVPAENA TVVPGKCPSP GCQEAFLTFL CVMCICSLIG 550
AMAQTPSVII LIRTVSPELK SYALGVLFLL LRLLGFIPPP LIFGAGIDST 600
CLFWSTFCGE QGACVLYDNV VYRYLYVSIA IALKSFAFIL YTTTWQCLRK 650
NYKRYIKNHE GGLSTSEFFA STLTLDNLGR DPVPANQTHR TKFIYNLEDH 700
EWCENMESVL 710
Length:710
Mass (Da):76,553
Last modified:May 18, 2010 - v3
Checksum:iED56724BA0998553
GO
Isoform 2 (identifier: Q9UIG8-2) [UniParc]FASTAAdd to Basket

Also known as: OATP3A1-v2

The sequence of this isoform differs from the canonical sequence as follows:
     667-692: EFFASTLTLDNLGRDPVPANQTHRTK → TEYQDIETEKTCPESHSPSEDSFVRS
     693-710: Missing.

Show »
Length:692
Mass (Da):74,372
Checksum:i2C7B72AC4C0E4E88
GO
Isoform 3 (identifier: Q9UIG8-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-58: Missing.
     59-60: YL → MN
     641-710: Missing.

Note: No experimental confirmation available.

Show »
Length:582
Mass (Da):62,203
Checksum:iE653AA86DA1BA276
GO
Isoform 4 (identifier: Q9UIG8-4) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-281: Missing.

Note: No experimental confirmation available.

Show »
Length:429
Mass (Da):46,411
Checksum:i822E718765321BC4
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti294 – 2941E → D.5 Publications
Corresponds to variant rs1517618 [ dbSNP | Ensembl ].
VAR_054853

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 281281Missing in isoform 4.
VSP_036833Add
BLAST
Alternative sequencei1 – 5858Missing in isoform 3.
VSP_036834Add
BLAST
Alternative sequencei59 – 602YL → MN in isoform 3.
VSP_036835
Alternative sequencei641 – 71070Missing in isoform 3.
VSP_036836Add
BLAST
Alternative sequencei667 – 69226EFFAS…THRTK → TEYQDIETEKTCPESHSPSE DSFVRS in isoform 2.
VSP_036837Add
BLAST
Alternative sequencei693 – 71018Missing in isoform 2.
VSP_036838Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti40 – 401K → R in BAF83561. 1 Publication
Sequence conflicti168 – 1681R → L in AAH00585. 1 Publication
Sequence conflicti188 – 1881G → D in BAF83561. 1 Publication
Sequence conflicti202 – 2021I → Y in BAA89287. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB031050 mRNA. Translation: BAA89287.1.
AF205074 mRNA. Translation: AAG42206.1.
AF187816 mRNA. Translation: AAG43446.1.
AK290872 mRNA. Translation: BAF83561.1.
AK057031 mRNA. Translation: BAG51847.1.
AK097797 mRNA. Translation: BAG53529.1.
FJ515841 Genomic DNA. Translation: ACS13734.1.
AC104020 Genomic DNA. No translation available.
AC104236 Genomic DNA. No translation available.
AC113190 Genomic DNA. No translation available.
AC116903 Genomic DNA. No translation available.
AC135996 Genomic DNA. No translation available.
BC000585 mRNA. Translation: AAH00585.1.
CCDSiCCDS10371.1. [Q9UIG8-1]
CCDS45354.1. [Q9UIG8-2]
RefSeqiNP_001138516.1. NM_001145044.1. [Q9UIG8-2]
NP_037404.2. NM_013272.3. [Q9UIG8-1]
UniGeneiHs.311187.

Genome annotation databases

EnsembliENST00000318445; ENSP00000320634; ENSG00000176463. [Q9UIG8-1]
ENST00000424469; ENSP00000387846; ENSG00000176463. [Q9UIG8-2]
GeneIDi28232.
KEGGihsa:28232.
UCSCiuc002bqx.2. human. [Q9UIG8-1]
uc002bqy.2. human. [Q9UIG8-2]

Polymorphism databases

DMDMi296452954.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB031050 mRNA. Translation: BAA89287.1 .
AF205074 mRNA. Translation: AAG42206.1 .
AF187816 mRNA. Translation: AAG43446.1 .
AK290872 mRNA. Translation: BAF83561.1 .
AK057031 mRNA. Translation: BAG51847.1 .
AK097797 mRNA. Translation: BAG53529.1 .
FJ515841 Genomic DNA. Translation: ACS13734.1 .
AC104020 Genomic DNA. No translation available.
AC104236 Genomic DNA. No translation available.
AC113190 Genomic DNA. No translation available.
AC116903 Genomic DNA. No translation available.
AC135996 Genomic DNA. No translation available.
BC000585 mRNA. Translation: AAH00585.1 .
CCDSi CCDS10371.1. [Q9UIG8-1 ]
CCDS45354.1. [Q9UIG8-2 ]
RefSeqi NP_001138516.1. NM_001145044.1. [Q9UIG8-2 ]
NP_037404.2. NM_013272.3. [Q9UIG8-1 ]
UniGenei Hs.311187.

3D structure databases

ProteinModelPortali Q9UIG8.
SMRi Q9UIG8. Positions 474-499.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q9UIG8. 1 interaction.
STRINGi 9606.ENSP00000320634.

Chemistry

ChEMBLi CHEMBL2073685.
GuidetoPHARMACOLOGYi 1225.

Protein family/group databases

TCDBi 2.A.60.1.18. the organo anion transporter (oat) family.

PTM databases

PhosphoSitei Q9UIG8.

Polymorphism databases

DMDMi 296452954.

Proteomic databases

MaxQBi Q9UIG8.
PaxDbi Q9UIG8.
PRIDEi Q9UIG8.

Protocols and materials databases

DNASUi 28232.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000318445 ; ENSP00000320634 ; ENSG00000176463 . [Q9UIG8-1 ]
ENST00000424469 ; ENSP00000387846 ; ENSG00000176463 . [Q9UIG8-2 ]
GeneIDi 28232.
KEGGi hsa:28232.
UCSCi uc002bqx.2. human. [Q9UIG8-1 ]
uc002bqy.2. human. [Q9UIG8-2 ]

Organism-specific databases

CTDi 28232.
GeneCardsi GC15P092396.
H-InvDB HIX0018979.
HGNCi HGNC:10952. SLCO3A1.
MIMi 612435. gene.
neXtProti NX_Q9UIG8.
PharmGKBi PA35837.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG320775.
HOVERGENi HBG098539.
InParanoidi Q9UIG8.
KOi K14353.
OMAi PANQTHR.
OrthoDBi EOG7GQXV6.
PhylomeDBi Q9UIG8.
TreeFami TF317540.

Enzyme and pathway databases

Reactomei REACT_23988. Transport of organic anions.

Miscellaneous databases

ChiTaRSi SLCO3A1. human.
GeneWikii SLCO3A1.
GenomeRNAii 28232.
NextBioi 50548.
PROi Q9UIG8.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q9UIG8.
Bgeei Q9UIG8.
CleanExi HS_SLCO3A1.
Genevestigatori Q9UIG8.

Family and domain databases

InterProi IPR002350. Kazal_dom.
IPR016196. MFS_dom_general_subst_transpt.
IPR004156. OA_transporter.
[Graphical view ]
PANTHERi PTHR11388. PTHR11388. 1 hit.
Pfami PF07648. Kazal_2. 1 hit.
PF03137. OATP. 1 hit.
[Graphical view ]
SMARTi SM00280. KAZAL. 1 hit.
[Graphical view ]
SUPFAMi SSF103473. SSF103473. 4 hits.
TIGRFAMsi TIGR00805. oat. 1 hit.
PROSITEi PS51465. KAZAL_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family."
    Tamai I., Nezu J., Uchino H., Sai Y., Oku A., Shimane M., Tsuji A.
    Biochem. Biophys. Res. Commun. 273:251-260(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, VARIANT ASP-294.
    Tissue: Kidney.
  2. "Identification and characterization of novel human OATP family members."
    Wu Y., Hsiang B.H., Zhu Y., Yang W.-P., Kirchgessner T.G.
    Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), VARIANT ASP-294.
  3. "Molecular identification of human PGE1 transporter expressed in cancer."
    Adachi H., Unno M., Matsuno S., Yawo H., Abe T.
    Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), VARIANT ASP-294.
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 3 AND 4), VARIANT ASP-294.
    Tissue: Mesangial cell and Testis.
  5. NHLBI resequencing and genotyping service (RS&G)
    Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  6. "Analysis of the DNA sequence and duplication history of human chromosome 15."
    Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N., Abouelleil A.
    , Arachchi H.M., Baradarani L., Birditt B., Bloom S., Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K., DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B., Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.
    Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), VARIANT ASP-294.
    Tissue: Brain.
  8. "Characterization of two splice variants of human organic anion transporting polypeptide 3A1 isolated from human brain."
    Huber R.D., Gao B., Sidler Pfaendler M.-A., Zhang-Fu W., Leuthold S., Hagenbuch B., Folkers G., Meier P.J., Stieger B.
    Am. J. Physiol. 292:C795-C806(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: ALTERNATIVE SPLICING, BIOPHYSICOCHEMICAL PROPERTIES, TISSUE SPECIFICITY.
  9. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiSO3A1_HUMAN
AccessioniPrimary (citable) accession number: Q9UIG8
Secondary accession number(s): A8K4A7
, B3KPY5, B3KUR7, C6G486, Q9BW73, Q9GZV2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 10, 2003
Last sequence update: May 18, 2010
Last modified: September 3, 2014
This is version 114 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi