Q9UHN6 (TMEM2_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Transmembrane protein 2

Gene names

Name:	TMEM2
Synonyms:	KIAA1412

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1383 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	May be required for the heart morphogenesis By similarity.
Subcellular location	Membrane; Single-pass membrane protein Potential.
Tissue specificity	Widely expressed. Ref.1
Sequence similarities	Belongs to the TMEM2 family. Contains 1 G8 domain. Contains 3 PbH1 repeats.
Sequence caution	The sequence BAA92650.2 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened. The sequence BAC11574.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended. The sequence CAI15172.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence CAI15173.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence CAI15174.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence CAI15175.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Cellular component	Membrane
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Repeat Transmembrane Transmembrane helix
Molecular function	Developmental protein
PTM	Glycoprotein Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	multicellular organismal development Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	integral to membrane Traceable author statement Ref.1. Source: ProtInc
Complete GO annotation...

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q9UHN6-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q9UHN6-2)

The sequence of this isoform differs from the canonical sequence as follows:
     402-464: Missing.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1383	1383	Transmembrane protein 2		PRO_0000289972
Regions
	Transmembrane	83 – 103	21	Helical; Potential
	Domain	121 – 245	125	G8
	Repeat	669 – 691	23	PbH1 1
	Repeat	711 – 733	23	PbH1 2
	Repeat	791 – 812	22	PbH1 3
Amino acid modifications
	Modified residue	10	1	Phosphoserine Ref.8
	Modified residue	63	1	Phosphoserine Ref.8
	Glycosylation	292	1	N-linked (GlcNAc...) Potential
	Glycosylation	914	1	N-linked (GlcNAc...) Potential
	Glycosylation	1234	1	N-linked (GlcNAc...) Potential
Natural variations
	Alternative sequence	402 – 464	63	Missing in isoform 2.		VSP_041401
	Natural variant	245	1	R → K. Corresponds to variant rs25688 [ dbSNP | Ensembl ].		VAR_032669
	Natural variant	291	1	R → H. Corresponds to variant rs25689 [ dbSNP | Ensembl ].		VAR_032670
	Natural variant	291	1	R → L. Corresponds to variant rs25689 [ dbSNP | Ensembl ].		VAR_062197
	Natural variant	291	1	R → P. Corresponds to variant rs25689 [ dbSNP | Ensembl ].		VAR_062198
	Natural variant	423	1	D → E. Corresponds to variant rs25695 [ dbSNP | Ensembl ].		VAR_032671
	Natural variant	765	1	P → S. Corresponds to variant rs25692 [ dbSNP | Ensembl ].		VAR_032672
	Natural variant	1010	1	I → V. Corresponds to variant rs17057133 [ dbSNP | Ensembl ].		VAR_032673
	Natural variant	1254	1	S → N. Corresponds to variant rs2297089 [ dbSNP | Ensembl ].		VAR_032674
	Natural variant	1280	1	G → D. Corresponds to variant rs17475375 [ dbSNP | Ensembl ].		VAR_032675
Experimental info
	Sequence conflict	1223	1	T → A in BAC11574. Ref.7
	Sequence conflict	1322	1	I → V in BAC11574. Ref.7

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 18954F8ADF94C317	FASTA	1,383	154,374
	10 20 30 40 50 60 MYATDSRGHS PAFLQPQNGN SRHPSGYVPG KVVPLRPPPP PKSQASAKFT SIRREDRATF 70 80 90 100 110 120 AFSPEEQQAQ RESQKQKRHK NTFICFAITS FSFFIALAII LGISSKYAPD ENCPDQNPRL 130 140 150 160 170 180 RNWDPGQDSA KQVVIKEGDM LRLTSDATVH SIVIQDGGLL VFGDNKDGSR NITLRTHYIL 190 200 210 220 230 240 IQDGGALHIG AEKCRYKSKA TITLYGKSDE GESMPTFGKK FIGVEAGGTL ELHGARKASW 250 260 270 280 290 300 TLLARTLNSS GLPFGSYTFE KDFSRGLNVR VIDQDTAKIL ESERFDTHEY RNESRRLQEF 310 320 330 340 350 360 LRFQDPGRIV AIAVGDSAAK SLLQGTIQMI QERLGSELIQ GLGYRQAWAL VGVIDGGSTS 370 380 390 400 410 420 CNESVRNYEN HSSGGKALAQ REFYTVDGQK FSVTAYSEWI EGVSLSGFRV EVVDGVKLNL 430 440 450 460 470 480 LDDVSSWKPG DQIVVASTDY SMYQAEEFTL LPCSECSHFQ VKVKETPQFL HMGEIIDGVD 490 500 510 520 530 540 MRAEVGILTR NIVIQGEVED SCYAENQCQF FDYDTFGGHI MIMKNFTSVH LSYVELKHMG 550 560 570 580 590 600 QQQMGRYPVH FHLCGDVDYK GGYRHATFVD GLSIHHSFSR CITVHGTNGL LIKDTIGFDT 610 620 630 640 650 660 LGHCFFLEDG IEQRNTLFHN LGLLTKPGTL LPTDRNNSMC TTMRDKVFGN YIPVPATDCM 670 680 690 700 710 720 AVSTFWIAHP NNNLINNAAA GSQDAGIWYL FHKEPTGESS GLQLLAKPEL TPLGIFYNNR 730 740 750 760 770 780 VHSNFKAGLF IDKGVKTTNS SAADPREYLC LDNSARFRPH QDANPEKPRV AALIDRLIAF 790 800 810 820 830 840 KNNDNGAWVR GGDIIVQNSA FADNGIGLTF ASDGSFPSDE GSSQEVSESL FVGESRNYGF 850 860 870 880 890 900 QGGQNKYVGT GGIDQKPRTL PRNRTFPIRG FQIYDGPIHL TRSTFKKYVP TPDRYSSAIG 910 920 930 940 950 960 FLMKNSWQIT PRNNISLVKF GPHVSLNVFF GKPGPWFEDC EMDGDKNSIF HDIDGSVTGY 970 980 990 1000 1010 1020 KDAYVGRMDN YLIRHPSCVN VSKWNAVICS GTYAQVYVQT WSTQNLSMTI TRDEYPSNPM 1030 1040 1050 1060 1070 1080 VLRGINQKAA FPQYQPVVML EKGYTIHWNG PAPRTTFLYL VNFNKNDWIR VGLCYPSNTS 1090 1100 1110 1120 1130 1140 FQVTFGYLQR QNGSLSKIEE YEPVHSLEEL QRKQSERKFY FDSSTGLLFL YLKAKSHRHG 1150 1160 1170 1180 1190 1200 HSYCSSQGCE RVKIQAATDS KDISNCMAKA YPQYYRKPSV VKRMPAMLTG LCQGCGTRQV 1210 1220 1230 1240 1250 1260 VFTSDPHKSY LPVQFQSPDK AETQRGDPSV ISVNGTDFTF RSAGVLLLVV DPCSVPFRLT 1270 1280 1290 1300 1310 1320 EKTVFPLADV SRIEEYLKTG IPPRSIVLLS TRGEIKQLNI SHLLVPLGLA KPAHLYDKGS 1330 1340 1350 1360 1370 1380 TIFLGFSGNF KPSWTKLFTS PAGQGLGVLE QFIPLQLDEY GCPRATTVRR RDLELLKQAS KAH
	Isoform 2 [UniParc]. Checksum: 7F4A1223B8BFBFF3	FASTA	1,320	147,439
	10 20 30 40 50 60 MYATDSRGHS PAFLQPQNGN SRHPSGYVPG KVVPLRPPPP PKSQASAKFT SIRREDRATF 70 80 90 100 110 120 AFSPEEQQAQ RESQKQKRHK NTFICFAITS FSFFIALAII LGISSKYAPD ENCPDQNPRL 130 140 150 160 170 180 RNWDPGQDSA KQVVIKEGDM LRLTSDATVH SIVIQDGGLL VFGDNKDGSR NITLRTHYIL 190 200 210 220 230 240 IQDGGALHIG AEKCRYKSKA TITLYGKSDE GESMPTFGKK FIGVEAGGTL ELHGARKASW 250 260 270 280 290 300 TLLARTLNSS GLPFGSYTFE KDFSRGLNVR VIDQDTAKIL ESERFDTHEY RNESRRLQEF 310 320 330 340 350 360 LRFQDPGRIV AIAVGDSAAK SLLQGTIQMI QERLGSELIQ GLGYRQAWAL VGVIDGGSTS 370 380 390 400 410 420 CNESVRNYEN HSSGGKALAQ REFYTVDGQK FSVTAYSEWI EETPQFLHMG EIIDGVDMRA 430 440 450 460 470 480 EVGILTRNIV IQGEVEDSCY AENQCQFFDY DTFGGHIMIM KNFTSVHLSY VELKHMGQQQ 490 500 510 520 530 540 MGRYPVHFHL CGDVDYKGGY RHATFVDGLS IHHSFSRCIT VHGTNGLLIK DTIGFDTLGH 550 560 570 580 590 600 CFFLEDGIEQ RNTLFHNLGL LTKPGTLLPT DRNNSMCTTM RDKVFGNYIP VPATDCMAVS 610 620 630 640 650 660 TFWIAHPNNN LINNAAAGSQ DAGIWYLFHK EPTGESSGLQ LLAKPELTPL GIFYNNRVHS 670 680 690 700 710 720 NFKAGLFIDK GVKTTNSSAA DPREYLCLDN SARFRPHQDA NPEKPRVAAL IDRLIAFKNN 730 740 750 760 770 780 DNGAWVRGGD IIVQNSAFAD NGIGLTFASD GSFPSDEGSS QEVSESLFVG ESRNYGFQGG 790 800 810 820 830 840 QNKYVGTGGI DQKPRTLPRN RTFPIRGFQI YDGPIHLTRS TFKKYVPTPD RYSSAIGFLM 850 860 870 880 890 900 KNSWQITPRN NISLVKFGPH VSLNVFFGKP GPWFEDCEMD GDKNSIFHDI DGSVTGYKDA 910 920 930 940 950 960 YVGRMDNYLI RHPSCVNVSK WNAVICSGTY AQVYVQTWST QNLSMTITRD EYPSNPMVLR 970 980 990 1000 1010 1020 GINQKAAFPQ YQPVVMLEKG YTIHWNGPAP RTTFLYLVNF NKNDWIRVGL CYPSNTSFQV 1030 1040 1050 1060 1070 1080 TFGYLQRQNG SLSKIEEYEP VHSLEELQRK QSERKFYFDS STGLLFLYLK AKSHRHGHSY 1090 1100 1110 1120 1130 1140 CSSQGCERVK IQAATDSKDI SNCMAKAYPQ YYRKPSVVKR MPAMLTGLCQ GCGTRQVVFT 1150 1160 1170 1180 1190 1200 SDPHKSYLPV QFQSPDKAET QRGDPSVISV NGTDFTFRSA GVLLLVVDPC SVPFRLTEKT 1210 1220 1230 1240 1250 1260 VFPLADVSRI EEYLKTGIPP RSIVLLSTRG EIKQLNISHL LVPLGLAKPA HLYDKGSTIF 1270 1280 1290 1300 1310 1320 LGFSGNFKPS WTKLFTSPAG QGLGVLEQFI PLQLDEYGCP RATTVRRRDL ELLKQASKAH

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Refining the DFNB7-DFNB11 deafness locus using intragenic polymorphisms in a novel gene, TMEM2." Scott D.A., Drury S., Sundstrom R.A., Bishop J., Swiderski R.E., Carmi R., Ramesh A., Elbedour K., Srikumari Srisailapathy C.R., Keats B.J., Sheffield V.C., Smith R.J.H. Gene 246:265-274(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY. Tissue: Fetal brain.
[2]	"Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro." Nagase T., Kikuno R., Ishikawa K., Hirosawa M., Ohara O. DNA Res. 7:65-73(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Tissue: Brain.
[3]	"Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones." Nakajima D., Okazaki N., Yamakawa H., Kikuno R., Ohara O., Nagase T. DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract] Cited for: SEQUENCE REVISION.
[4]	"DNA sequence and analysis of human chromosome 9." Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L. , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I. Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[6]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
[7]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 579-1383. Tissue: Teratocarcinoma.
[8]	"A quantitative atlas of mitotic phosphorylation." Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-10 AND SER-63, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[9]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF137030 mRNA. Translation: AAF21348.1. AB037833 mRNA. Translation: BAA92650.2. Different initiation. AL161732 Genomic DNA. Translation: CAI15172.1. Sequence problems. AL161732 Genomic DNA. Translation: CAI15173.1. Sequence problems. AL161732 Genomic DNA. Translation: CAI15174.1. Sequence problems. AL161732 Genomic DNA. Translation: CAI15175.1. Sequence problems. AL161732 Genomic DNA. Translation: CAI15176.1. CH471089 Genomic DNA. Translation: EAW62518.1. BC140773 mRNA. Translation: AAI40774.1. BC146780 mRNA. Translation: AAI46781.1. AK075370 mRNA. Translation: BAC11574.1. Different initiation.
IPI	IPI00170706. IPI01011640.
RefSeq	NP_001129292.1. NM_001135820.1. NP_037522.1. NM_013390.2.
UniGene	Hs.494146.
3D structure databases
ProteinModelPortal	Q9UHN6.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9UHN6. 1 interaction.
STRING	9606.ENSP00000366266.
PTM databases
PhosphoSite	Q9UHN6.
Polymorphism databases
DMDM	74753330.
Proteomic databases
PaxDb	Q9UHN6.
PRIDE	Q9UHN6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000377044; ENSP00000366243; ENSG00000135048. ENST00000377066; ENSP00000366266; ENSG00000135048.
GeneID	23670.
KEGG	hsa:23670.
UCSC	uc010mos.2. human. uc011lsa.1. human.
Organism-specific databases
CTD	23670.
GeneCards	GC09M074298.
HGNC	HGNC:11869. TMEM2.
HPA	HPA044889.
MIM	605835. gene.
neXtProt	NX_Q9UHN6.
PharmGKB	PA36570.
HUGE	Search...
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG12793.
HOVERGEN	HBG052198.
InParanoid	Q9UHN6.
OMA	RNYGFQG.
OrthoDB	EOG4DR9BF.
PhylomeDB	Q9UHN6.
Gene expression databases
ArrayExpress	Q9UHN6.
Bgee	Q9UHN6.
CleanEx	HS_TMEM2.
Genevestigator	Q9UHN6.
Family and domain databases
InterPro	IPR019316. G8_domain. IPR011050. Pectin_lyase_fold/virulence. [Graphical view]
Pfam	PF10162. G8. 1 hit. [Graphical view]
SUPFAM	SSF51126. Pectin_lyas_like. 1 hit.
PROSITE	PS51484. G8. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	TMEM2. human.
GenomeRNAi	23670.
NextBio	46523.
SOURCE	Search...

Entry information

Entry name

TMEM2_HUMAN

Accession

Primary (citable) accession number: Q9UHN6
Secondary accession number(s): A6H8W9 , B2RTQ6, Q5T838, Q5T839, Q5T840, Q5T841, Q8NBP6, Q9P2D5

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 12, 2007
Last sequence update:	May 1, 2000
Last modified:	April 3, 2013
This is version 80 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.