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Protein

Protein FAM153A

Gene

FAM153A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM153A
Alternative name(s):
Renal carcinoma antigen NY-REN-7
Gene namesi
Name:FAM153A
Synonyms:KIAA0752
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

HGNCiHGNC:29940. FAM153A.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162386535.

Polymorphism and mutation databases

BioMutaiFAM153A.
DMDMi229462851.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 310310Protein FAM153APRO_0000318156Add
BLAST

Proteomic databases

PaxDbiQ9UHL3.
PRIDEiQ9UHL3.

PTM databases

iPTMnetiQ9UHL3.
PhosphoSiteiQ9UHL3.

Expressioni

Gene expression databases

BgeeiENSG00000170074.
CleanExiHS_FAM153A.
ExpressionAtlasiQ9UHL3. baseline and differential.
GenevisibleiQ9UHL3. HS.

Organism-specific databases

HPAiHPA042585.
HPA044022.
HPA046691.
HPA052337.
HPA055498.

Interactioni

Protein-protein interaction databases

BioGridi130152. 2 interactions.
IntActiQ9UHL3. 1 interaction.
STRINGi9606.ENSP00000353887.

Structurei

3D structure databases

ProteinModelPortaliQ9UHL3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAM153 family.Curated

Phylogenomic databases

eggNOGiENOG410KIIN. Eukaryota.
ENOG4110Q72. LUCA.
GeneTreeiENSGT00530000064897.
HOGENOMiHOG000015270.
HOVERGENiHBG102425.
InParanoidiQ9UHL3.
PhylomeDBiQ9UHL3.
TreeFamiTF353284.

Family and domain databases

InterProiIPR023249. FAM153.
[Graphical view]
PANTHERiPTHR40712. PTHR40712. 1 hit.
PfamiPF15722. FAM153. 4 hits.
[Graphical view]
PRINTSiPR02041. PROTEINF153.

Sequencei

Sequence statusi: Complete.

Q9UHL3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVDKDTERDI EMKRQLRRLR ELHLYSTWKK YQEAMKTSLG VPQCERDEGS
60 70 80 90 100
LGKPLCPPEI LSETLPGSVK KRVCFPSEDH LEEFIAEHLP EASNQSLLTV
110 120 130 140 150
AHADAGTQTN GDLEDLEEHG PGQTVSEEAT EVHTMEGDPD TLAEFLIRDV
160 170 180 190 200
LQELSSYNGE EEDPEEVKTS LGVPQRGDLE DLEEHVPGQT VSEEATGVHM
210 220 230 240 250
MQVDPATLAK SDLEDLEEHV PEQTVSEEAT GVHMMQVDPA TLAKQLEDST
260 270 280 290 300
ITGSHQQMSA SPSSAPAEEA TEKTKVEEEV KTRKPKKKTR KPSKKSRWNV
310
LKCWDIFNIF
Length:310
Mass (Da):34,712
Last modified:May 5, 2009 - v2
Checksum:i2E3E31A74BF40DE8
GO

Sequence cautioni

The sequence BAA34472 differs from that shown. Reason: Erroneous initiation. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti44 – 441C → R in AAD42863 (PubMed:10508479).Curated
Sequence conflicti44 – 441C → R in BAA34472 (PubMed:9872452).Curated
Sequence conflicti44 – 441C → R in BAF82207 (PubMed:14702039).Curated
Sequence conflicti134 – 1341T → M in AAD42863 (PubMed:10508479).Curated
Sequence conflicti134 – 1341T → M in BAA34472 (PubMed:9872452).Curated
Sequence conflicti134 – 1341T → M in BAF82207 (PubMed:14702039).Curated
Sequence conflicti137 – 1371G → E in BAF82207 (PubMed:14702039).Curated
Sequence conflicti145 – 1451F → L in AAD42863 (PubMed:10508479).Curated
Sequence conflicti145 – 1451F → L in BAA34472 (PubMed:9872452).Curated
Sequence conflicti145 – 1451F → L in BAF82207 (PubMed:14702039).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF155097 mRNA. Translation: AAD42863.1.
AB018295 mRNA. Translation: BAA34472.1. Different initiation.
AK289518 mRNA. Translation: BAF82207.1.
AC140125 Genomic DNA. No translation available.
CCDSiCCDS34305.1.
RefSeqiNP_775934.3. NM_173663.3.
XP_006714911.1. XM_006714848.3.
XP_006714912.1. XM_006714849.3.
XP_011532823.1. XM_011534521.2.
XP_011532824.1. XM_011534522.2.
XP_011532825.1. XM_011534523.2.
UniGeneiHs.368516.
Hs.652754.

Genome annotation databases

EnsembliENST00000360669; ENSP00000353887; ENSG00000170074.
ENST00000440605; ENSP00000411506; ENSG00000170074.
ENST00000510276; ENSP00000422174; ENSG00000170074.
GeneIDi285596.
KEGGihsa:285596.
UCSCiuc003mic.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF155097 mRNA. Translation: AAD42863.1.
AB018295 mRNA. Translation: BAA34472.1. Different initiation.
AK289518 mRNA. Translation: BAF82207.1.
AC140125 Genomic DNA. No translation available.
CCDSiCCDS34305.1.
RefSeqiNP_775934.3. NM_173663.3.
XP_006714911.1. XM_006714848.3.
XP_006714912.1. XM_006714849.3.
XP_011532823.1. XM_011534521.2.
XP_011532824.1. XM_011534522.2.
XP_011532825.1. XM_011534523.2.
UniGeneiHs.368516.
Hs.652754.

3D structure databases

ProteinModelPortaliQ9UHL3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi130152. 2 interactions.
IntActiQ9UHL3. 1 interaction.
STRINGi9606.ENSP00000353887.

PTM databases

iPTMnetiQ9UHL3.
PhosphoSiteiQ9UHL3.

Polymorphism and mutation databases

BioMutaiFAM153A.
DMDMi229462851.

Proteomic databases

PaxDbiQ9UHL3.
PRIDEiQ9UHL3.

Protocols and materials databases

DNASUi285596.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000360669; ENSP00000353887; ENSG00000170074.
ENST00000440605; ENSP00000411506; ENSG00000170074.
ENST00000510276; ENSP00000422174; ENSG00000170074.
GeneIDi285596.
KEGGihsa:285596.
UCSCiuc003mic.4. human.

Organism-specific databases

CTDi285596.
GeneCardsiFAM153A.
H-InvDBHIX0019692.
HIX0057489.
HGNCiHGNC:29940. FAM153A.
HPAiHPA042585.
HPA044022.
HPA046691.
HPA052337.
HPA055498.
neXtProtiNX_Q9UHL3.
PharmGKBiPA162386535.
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410KIIN. Eukaryota.
ENOG4110Q72. LUCA.
GeneTreeiENSGT00530000064897.
HOGENOMiHOG000015270.
HOVERGENiHBG102425.
InParanoidiQ9UHL3.
PhylomeDBiQ9UHL3.
TreeFamiTF353284.

Miscellaneous databases

ChiTaRSiFAM153A. human.
GenomeRNAii285596.
PROiQ9UHL3.

Gene expression databases

BgeeiENSG00000170074.
CleanExiHS_FAM153A.
ExpressionAtlasiQ9UHL3. baseline and differential.
GenevisibleiQ9UHL3. HS.

Family and domain databases

InterProiIPR023249. FAM153.
[Graphical view]
PANTHERiPTHR40712. PTHR40712. 1 hit.
PfamiPF15722. FAM153. 4 hits.
[Graphical view]
PRINTSiPR02041. PROTEINF153.
ProtoNetiSearch...

Entry informationi

Entry nameiF153A_HUMAN
AccessioniPrimary (citable) accession number: Q9UHL3
Secondary accession number(s): A8K0F3, O94852
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: May 5, 2009
Last modified: September 7, 2016
This is version 84 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.