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Protein

Protein FAM153A

Gene

FAM153A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM153A
Alternative name(s):
Renal carcinoma antigen NY-REN-7
Gene namesi
Name:FAM153A
Synonyms:KIAA0752
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiHostDB:ENSG00000170074.19
HGNCiHGNC:29940 FAM153A
neXtProtiNX_Q9UHL3

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000170074
PharmGKBiPA162386535

Polymorphism and mutation databases

BioMutaiFAM153A
DMDMi229462851

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003181561 – 310Protein FAM153AAdd BLAST310

Proteomic databases

PaxDbiQ9UHL3
PRIDEiQ9UHL3
ProteomicsDBi84374

PTM databases

iPTMnetiQ9UHL3
PhosphoSitePlusiQ9UHL3

Expressioni

Gene expression databases

BgeeiENSG00000170074
CleanExiHS_FAM153A
ExpressionAtlasiQ9UHL3 baseline and differential
GenevisibleiQ9UHL3 HS

Organism-specific databases

HPAiHPA042585
HPA044022
HPA046691
HPA052337
HPA055498

Interactioni

Protein-protein interaction databases

BioGridi130152, 2 interactors
IntActiQ9UHL3, 3 interactors
STRINGi9606.ENSP00000353887

Structurei

3D structure databases

ProteinModelPortaliQ9UHL3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAM153 family.Curated

Phylogenomic databases

eggNOGiENOG410KIIN Eukaryota
ENOG4110Q72 LUCA
GeneTreeiENSGT00530000064897
HOGENOMiHOG000015270
HOVERGENiHBG102425
InParanoidiQ9UHL3
PhylomeDBiQ9UHL3
TreeFamiTF353284

Family and domain databases

InterProiView protein in InterPro
IPR023249 FAM153
PANTHERiPTHR40712 PTHR40712, 1 hit
PfamiView protein in Pfam
PF15722 FAM153, 4 hits
PRINTSiPR02041 PROTEINF153

Sequencei

Sequence statusi: Complete.

Q9UHL3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVDKDTERDI EMKRQLRRLR ELHLYSTWKK YQEAMKTSLG VPQCERDEGS
60 70 80 90 100
LGKPLCPPEI LSETLPGSVK KRVCFPSEDH LEEFIAEHLP EASNQSLLTV
110 120 130 140 150
AHADAGTQTN GDLEDLEEHG PGQTVSEEAT EVHTMEGDPD TLAEFLIRDV
160 170 180 190 200
LQELSSYNGE EEDPEEVKTS LGVPQRGDLE DLEEHVPGQT VSEEATGVHM
210 220 230 240 250
MQVDPATLAK SDLEDLEEHV PEQTVSEEAT GVHMMQVDPA TLAKQLEDST
260 270 280 290 300
ITGSHQQMSA SPSSAPAEEA TEKTKVEEEV KTRKPKKKTR KPSKKSRWNV
310
LKCWDIFNIF
Length:310
Mass (Da):34,712
Last modified:May 5, 2009 - v2
Checksum:i2E3E31A74BF40DE8
GO

Sequence cautioni

The sequence BAA34472 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti44C → R in AAD42863 (PubMed:10508479).Curated1
Sequence conflicti44C → R in BAA34472 (PubMed:9872452).Curated1
Sequence conflicti44C → R in BAF82207 (PubMed:14702039).Curated1
Sequence conflicti134T → M in AAD42863 (PubMed:10508479).Curated1
Sequence conflicti134T → M in BAA34472 (PubMed:9872452).Curated1
Sequence conflicti134T → M in BAF82207 (PubMed:14702039).Curated1
Sequence conflicti137G → E in BAF82207 (PubMed:14702039).Curated1
Sequence conflicti145F → L in AAD42863 (PubMed:10508479).Curated1
Sequence conflicti145F → L in BAA34472 (PubMed:9872452).Curated1
Sequence conflicti145F → L in BAF82207 (PubMed:14702039).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF155097 mRNA Translation: AAD42863.1
AB018295 mRNA Translation: BAA34472.1 Different initiation.
AK289518 mRNA Translation: BAF82207.1
AC140125 Genomic DNA No translation available.
CCDSiCCDS34305.1
RefSeqiNP_775934.3, NM_173663.3
XP_006714911.1, XM_006714848.3
XP_006714912.1, XM_006714849.3
XP_011532823.1, XM_011534521.2
XP_011532824.1, XM_011534522.2
XP_011532825.1, XM_011534523.2
XP_016864855.1, XM_017009366.1
XP_016864856.1, XM_017009367.1
XP_016864857.1, XM_017009368.1
XP_016864858.1, XM_017009369.1
XP_016864859.1, XM_017009370.1
XP_016864860.1, XM_017009371.1
UniGeneiHs.368516
Hs.652754
Hs.653068

Genome annotation databases

EnsembliENST00000360669; ENSP00000353887; ENSG00000170074
ENST00000440605; ENSP00000411506; ENSG00000170074
ENST00000510276; ENSP00000422174; ENSG00000170074
GeneIDi285596
KEGGihsa:285596
UCSCiuc003mic.4 human

Similar proteinsi

Entry informationi

Entry nameiF153A_HUMAN
AccessioniPrimary (citable) accession number: Q9UHL3
Secondary accession number(s): A8K0F3, O94852
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: May 5, 2009
Last modified: June 20, 2018
This is version 90 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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