Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9UHA3

- RLP24_HUMAN

UniProt

Q9UHA3 - RLP24_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable ribosome biogenesis protein RLP24

Gene

RSL24D1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of GTPBP4/NOG1 to pre-60S particles (By similarity).By similarity

GO - Biological processi

  1. ribosome biogenesis Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Ribosome biogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
Probable ribosome biogenesis protein RLP24
Alternative name(s):
Ribosomal L24 domain-containing protein 1
Ribosomal protein L24-like
Gene namesi
Name:RSL24D1
Synonyms:C15orf15, RPL24L
ORF Names:My024
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 15

Organism-specific databases

HGNCiHGNC:18479. RSL24D1.

Subcellular locationi

Nucleusnucleolus 1 Publication

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA164725551.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 163163Probable ribosome biogenesis protein RLP24PRO_0000136896Add
BLAST

Proteomic databases

MaxQBiQ9UHA3.
PaxDbiQ9UHA3.
PRIDEiQ9UHA3.

2D gel databases

SWISS-2DPAGEQ9UHA3.

PTM databases

PhosphoSiteiQ9UHA3.

Expressioni

Gene expression databases

BgeeiQ9UHA3.
CleanExiHS_C15orf15.
ExpressionAtlasiQ9UHA3. baseline and differential.
GenevestigatoriQ9UHA3.

Interactioni

Subunit structurei

Associated with nucleolar and cytoplasmic pre-60S particles. At the end of biogenesis it dissociates from cytoplasmic pre-60S particles and is likely to be exchanged for its ribosomal homolog, RPL24 (By similarity).By similarity

Protein-protein interaction databases

BioGridi119362. 10 interactions.
IntActiQ9UHA3. 1 interaction.
MINTiMINT-1448265.
STRINGi9606.ENSP00000260443.

Structurei

3D structure databases

ProteinModelPortaliQ9UHA3.
SMRiQ9UHA3. Positions 1-85.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L24e family.Curated

Phylogenomic databases

eggNOGiCOG2075.
GeneTreeiENSGT00550000074895.
HOVERGENiHBG105577.
InParanoidiQ9UHA3.
KOiK02896.
OMAiIKAPHAG.
OrthoDBiEOG7J9VR0.
PhylomeDBiQ9UHA3.
TreeFamiTF314926.

Family and domain databases

Gene3Di2.30.170.20. 1 hit.
HAMAPiMF_00773. Ribosomal_L24e.
InterProiIPR023442. Ribosomal_L24e_CS.
IPR023441. Ribosomal_L24e_dom.
IPR000988. Ribosomal_L24e_rel.
IPR024546. Ribosome_biogen_RLP24.
IPR011017. TRASH_dom.
[Graphical view]
PANTHERiPTHR10792. PTHR10792. 1 hit.
PTHR10792:SF8. PTHR10792:SF8. 1 hit.
PfamiPF01246. Ribosomal_L24e. 1 hit.
[Graphical view]
SMARTiSM00746. TRASH. 1 hit.
[Graphical view]
PROSITEiPS01073. RIBOSOMAL_L24E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9UHA3 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRIEKCYFCS GPIYPGHGMM FVRNDCKVFR FCKSKCHKNF KKKRNPRKVR
60 70 80 90 100
WTKAFRKAAG KELTVDNSFE FEKRRNEPIK YQRELWNKTI DAMKRVEEIK
110 120 130 140 150
QKRQAKFIMN RLKKNKELQK VQDIKEVKQN IHLIRAPLAG KGKQLEEKMV
160
QQLQEDVDME DAP
Length:163
Mass (Da):19,621
Last modified:May 1, 2000 - v1
Checksum:i1E5D9ECFFCF678D1
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti29 – 291F → I in AAH08499. (PubMed:15489334)Curated
Sequence conflicti30 – 301R → G in AAH14576. (PubMed:15489334)Curated
Sequence conflicti45 – 451N → D in AAH28672. (PubMed:15489334)Curated
Sequence conflicti86 – 861W → R in AAH16312. (PubMed:15489334)Curated
Sequence conflicti146 – 1461E → G in AAH28672. (PubMed:15489334)Curated

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF201949 mRNA. Translation: AAF17241.1.
AF060926 mRNA. Translation: AAG43138.1.
AF165521 mRNA. Translation: AAF86651.1.
AF212226 mRNA. Translation: AAK26249.1.
CR457179 mRNA. Translation: CAG33460.1.
AK315431 mRNA. Translation: BAG37819.1.
CH471082 Genomic DNA. Translation: EAW77473.1.
BC008409 mRNA. Translation: AAH08409.1.
BC008422 mRNA. Translation: AAH08422.1.
BC008449 mRNA. Translation: AAH08449.1.
BC008499 mRNA. Translation: AAH08499.1.
BC009593 mRNA. Translation: AAH09593.1.
BC009604 mRNA. Translation: AAH09604.1.
BC012913 mRNA. Translation: AAH12913.1.
BC014576 mRNA. Translation: AAH14576.1.
BC016312 mRNA. Translation: AAH16312.1.
BC016331 mRNA. Translation: AAH16331.1.
BC016725 mRNA. Translation: AAH16725.1.
BC016777 mRNA. Translation: AAH16777.1.
BC026266 mRNA. Translation: AAH26266.1.
BC026267 mRNA. Translation: AAH26267.1.
BC028672 mRNA. Translation: AAH28672.1.
BC035995 mRNA. Translation: AAH35995.1.
BC093067 mRNA. Translation: AAH93067.1.
CCDSiCCDS10152.1.
RefSeqiNP_057388.1. NM_016304.2.
UniGeneiHs.274772.

Genome annotation databases

EnsembliENST00000260443; ENSP00000260443; ENSG00000137876.
GeneIDi51187.
KEGGihsa:51187.
UCSCiuc002acn.3. human.

Polymorphism databases

DMDMi52783333.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF201949 mRNA. Translation: AAF17241.1 .
AF060926 mRNA. Translation: AAG43138.1 .
AF165521 mRNA. Translation: AAF86651.1 .
AF212226 mRNA. Translation: AAK26249.1 .
CR457179 mRNA. Translation: CAG33460.1 .
AK315431 mRNA. Translation: BAG37819.1 .
CH471082 Genomic DNA. Translation: EAW77473.1 .
BC008409 mRNA. Translation: AAH08409.1 .
BC008422 mRNA. Translation: AAH08422.1 .
BC008449 mRNA. Translation: AAH08449.1 .
BC008499 mRNA. Translation: AAH08499.1 .
BC009593 mRNA. Translation: AAH09593.1 .
BC009604 mRNA. Translation: AAH09604.1 .
BC012913 mRNA. Translation: AAH12913.1 .
BC014576 mRNA. Translation: AAH14576.1 .
BC016312 mRNA. Translation: AAH16312.1 .
BC016331 mRNA. Translation: AAH16331.1 .
BC016725 mRNA. Translation: AAH16725.1 .
BC016777 mRNA. Translation: AAH16777.1 .
BC026266 mRNA. Translation: AAH26266.1 .
BC026267 mRNA. Translation: AAH26267.1 .
BC028672 mRNA. Translation: AAH28672.1 .
BC035995 mRNA. Translation: AAH35995.1 .
BC093067 mRNA. Translation: AAH93067.1 .
CCDSi CCDS10152.1.
RefSeqi NP_057388.1. NM_016304.2.
UniGenei Hs.274772.

3D structure databases

ProteinModelPortali Q9UHA3.
SMRi Q9UHA3. Positions 1-85.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 119362. 10 interactions.
IntActi Q9UHA3. 1 interaction.
MINTi MINT-1448265.
STRINGi 9606.ENSP00000260443.

PTM databases

PhosphoSitei Q9UHA3.

Polymorphism databases

DMDMi 52783333.

2D gel databases

SWISS-2DPAGE Q9UHA3.

Proteomic databases

MaxQBi Q9UHA3.
PaxDbi Q9UHA3.
PRIDEi Q9UHA3.

Protocols and materials databases

DNASUi 51187.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000260443 ; ENSP00000260443 ; ENSG00000137876 .
GeneIDi 51187.
KEGGi hsa:51187.
UCSCi uc002acn.3. human.

Organism-specific databases

CTDi 51187.
GeneCardsi GC15M055473.
HGNCi HGNC:18479. RSL24D1.
MIMi 613262. gene.
neXtProti NX_Q9UHA3.
PharmGKBi PA164725551.
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG2075.
GeneTreei ENSGT00550000074895.
HOVERGENi HBG105577.
InParanoidi Q9UHA3.
KOi K02896.
OMAi IKAPHAG.
OrthoDBi EOG7J9VR0.
PhylomeDBi Q9UHA3.
TreeFami TF314926.

Miscellaneous databases

GeneWikii C15orf15.
GenomeRNAii 51187.
NextBioi 54173.
PROi Q9UHA3.
SOURCEi Search...

Gene expression databases

Bgeei Q9UHA3.
CleanExi HS_C15orf15.
ExpressionAtlasi Q9UHA3. baseline and differential.
Genevestigatori Q9UHA3.

Family and domain databases

Gene3Di 2.30.170.20. 1 hit.
HAMAPi MF_00773. Ribosomal_L24e.
InterProi IPR023442. Ribosomal_L24e_CS.
IPR023441. Ribosomal_L24e_dom.
IPR000988. Ribosomal_L24e_rel.
IPR024546. Ribosome_biogen_RLP24.
IPR011017. TRASH_dom.
[Graphical view ]
PANTHERi PTHR10792. PTHR10792. 1 hit.
PTHR10792:SF8. PTHR10792:SF8. 1 hit.
Pfami PF01246. Ribosomal_L24e. 1 hit.
[Graphical view ]
SMARTi SM00746. TRASH. 1 hit.
[Graphical view ]
PROSITEi PS01073. RIBOSOMAL_L24E. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Novel genes expressed in human dendritic cells."
    Li Y., Peng Y., Li N., Gu W., Han Z., Fu G., Chen Z.
    Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Dendritic cell.
  2. Mao Y.M., Xie Y., Lin Q., Mu Z.M., Yuan Y.Z.
    Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Fetal brain.
  3. "Novel genes expressed in hematopoietic stem/progenitor cells from myelodysplastic syndrome patients."
    Gu J., Huang Q., Yu Y., Xu S., Wang Y., Han Z., Chen Z., Zhou J., Tu Y., Gu W., Fu G., Huang C.
    Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Hematopoietic stem cell.
  4. "A novel gene expressed in human liver."
    Peng Y., Li Y., Tu Y., Xu S., Han Z., Fu G., Chen Z.
    Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Liver.
  5. "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
    Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
    Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  6. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.
  7. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  8. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Blood, Bone marrow, Brain, Lung and Urinary bladder.
  9. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.

Entry informationi

Entry nameiRLP24_HUMAN
AccessioniPrimary (citable) accession number: Q9UHA3
Secondary accession number(s): B2RD72
, Q561V8, Q8N6S8, Q96B04, Q96C76, Q96HJ1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 27, 2004
Last sequence update: May 1, 2000
Last modified: October 29, 2014
This is version 113 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3