UniProtKB - Q9UGM3 (DMBT1_HUMAN)
(max 400 entries)x
Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>
Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)
- BLAST>sp|Q9UGM3|DMBT1_HUMAN Deleted in malignant brain tumors 1 protein OS=Homo sapiens OX=9606 GN=DMBT1 PE=1 SV=2 MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTV AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTIT LPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSL ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQG SGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITL PPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAT SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPT PSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVC RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVI CSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDD SWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH NCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYR GSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWS CPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRC QGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC SGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLAL RLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSG PIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRAST AGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPG NAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPD TWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ LGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS ATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNS GYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFR SDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEA EVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHRED AGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEV QNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFI SDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYY ECRPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVSCRM LQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQ DLYVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIA RFRFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPI QLQTPPRREEEPR
- Align
Protein
Deleted in malignant brain tumors 1 protein
Gene
DMBT1
Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:
Annotation score:5 out of 5
<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>Select a section on the left to see content.
<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni
May be considered as a candidate tumor suppressor gene for brain, lung, esophageal, gastric, and colorectal cancers. May play roles in mucosal defense system, cellular immune defense and epithelial differentiation. May play a role as an opsonin receptor for SFTPD and SPAR in macrophage tissues throughout the body, including epithelial cells lining the gastrointestinal tract. May play a role in liver regeneration. May be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lineage. Required for terminal differentiation of columnar epithelial cells during early embryogenesis. May function as a binding protein in saliva for the regulation of taste sensation. Binds to HIV-1 envelope protein and has been shown to both inhibit and facilitate viral transmission. Displays a broad calcium-dependent binding spectrum against both Gram-positive and Gram-negative bacteria, suggesting a role in defense against bacterial pathogens. Binds to a range of poly-sulfated and poly-phosphorylated ligands which may explain its broad bacterial-binding specificity. Inhibits cytoinvasion of S.enterica. Associates with the actin cytoskeleton and is involved in its remodeling during regulated exocytosis. Interacts with pancreatic zymogens in a pH-dependent manner and may act as a Golgi cargo receptor in the regulated secretory pathway of the pancreatic acinar cell.8 Publications
<p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
- Ref.1"DMBT1, a new member of the SRCR superfamily on chromosome 10q25.3-q26.1 is deleted in malignant brain tumours."
Mollenhauer J., Wiemann S., Scheurlen W., Korn B., Hayashi Y., Wilgenbus K.K., von Deimling A., Poustka A.
Nat. Genet. 17:32-39(1997) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), FUNCTION AS A TUMOR SUPPRESSOR, TISSUE SPECIFICITY, VARIANTS THR-42 AND ALA-60. - Ref.2"Cloning of gp-340, a putative opsonin receptor for lung surfactant protein D."
Holmskov U., Mollenhauer J., Madsen J., Vitved L., Gronlund J., Tornoe I., Kliem A., Reid K.B.M., Poustka A., Skjodt K.
Proc. Natl. Acad. Sci. U.S.A. 96:10794-10799(1999) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION IN MUCOSAL AND CELLULAR IMMUNE DEFENSE, TISSUE SPECIFICITY, SUBCELLULAR LOCATION, DEVELOPMENTAL STAGE, VARIANTS THR-42; LEU-54; ALA-60; MET-649; MET-780 AND SER-856. - Ref.5"Deleted in malignant brain tumors 1 is a versatile mucin-like molecule likely to play a differential role in digestive tract cancer."
Mollenhauer J., Herbertz S., Helmke B., Kollender G., Krebs I., Madsen J., Holmskov U., Sorger K., Schmitt L., Wiemann S., Otto H.F., Grone H.-J., Poustka A.
Cancer Res. 61:8880-8886(2001) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION IN EPITHELIAL DIFFERENTIATION, TISSUE SPECIFICITY, ALTERNATIVE SPLICING, INVOLVEMENT IN ESOPHAGEAL CARCINOMAS, VARIANT SER-856. - Ref.16"Salivary agglutinin, which binds Streptococcus mutans and Helicobacter pylori, is the lung scavenger receptor cysteine-rich protein gp-340."
Prakobphol A., Xu F., Hoang V.M., Larsson T., Bergstrom J., Johansson I., Fraengsmyr L., Holmskov U., Leffler H., Nilsson C., Boren T., Wright J.R., Stroemberg N., Fisher S.J.
J. Biol. Chem. 275:39860-39866(2000) [PubMed] [Europe PMC] [Abstract]Cited for: IDENTIFICATION BY MASS SPECTROMETRY, FUNCTION. - Ref.18"The N-terminal SRCR-SID domain of gp-340 interacts with HIV type 1 gp120 sequences and inhibits viral infection."
Wu Z., Lee S., Abrams W., Weissman D., Malamud D.
AIDS Res. Hum. Retroviruses 22:508-515(2006) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, INTERACTION WITH HIV-1 GP120, TISSUE SPECIFICITY. - Ref.21"Regulation of DMBT1 via NOD2 and TLR4 in intestinal epithelial cells modulates bacterial recognition and invasion."
Rosenstiel P., Sina C., End C., Renner M., Lyer S., Till A., Hellmig S., Nikolaus S., Foelsch U.R., Helmke B., Autschbach F., Schirmacher P., Kioschis P., Hafner M., Poustka A., Mollenhauer J., Schreiber S.
J. Immunol. 178:8203-8211(2007) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, TISSUE SPECIFICITY, INDUCTION. - Ref.22"gp340 expressed on human genital epithelia binds HIV-1 envelope protein and facilitates viral transmission."
Stoddard E., Cannon G., Ni H., Kariko K., Capodici J., Malamud D., Weissman D.
J. Immunol. 179:3126-3132(2007) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION. - Ref.24"DMBT1 functions as pattern-recognition molecule for poly-sulfated and poly-phosphorylated ligands."
End C., Bikker F., Renner M., Bergmann G., Lyer S., Blaich S., Hudler M., Helmke B., Gassler N., Autschbach F., Ligtenberg A.J.M., Benner A., Holmskov U., Schirmacher P., Nieuw Amerongen A.V., Rosenstiel P., Sina C., Franke A. , Hafner M., Kioschis P., Schreiber S., Poustka A., Mollenhauer J.
Eur. J. Immunol. 39:833-842(2009) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION.
<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni
- calcium-dependent protein binding Source: UniProtKB <p>Traceable Author Statement</p> <p>Used for information from review articles where the original experiments are traceable through that article and also for information from text books or dictionaries.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#tas">GO evidence code guide</a></p> Traceable author statementi
- DNA binding Source: UniProtKB <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
- heparan sulfate binding Source: UniProtKB <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
- lipopolysaccharide binding Source: UniProtKB <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
- lipoteichoic acid binding Source: UniProtKB <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
- pattern recognition receptor activity Source: UniProtKB <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
- scavenger receptor activity Source: UniProtKB <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
- signaling pattern recognition receptor activity Source: UniProtKB <p>Traceable Author Statement</p> <p>Used for information from review articles where the original experiments are traceable through that article and also for information from text books or dictionaries.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#tas">GO evidence code guide</a></p> Traceable author statementi
- zymogen binding Source: UniProtKB
<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi
- antimicrobial humoral immune response mediated by antimicrobial peptide Source: UniProtKB <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
- cellular protein metabolic process Source: Reactome
- defense response to Gram-negative bacterium Source: UniProtKB <p>Inferred from Mutant Phenotype</p> <p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypei
- defense response to Gram-positive bacterium Source: UniProtKB <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
- defense response to virus Source: UniProtKB-KW
- epithelial cell differentiation Source: UniProtKB <p>Traceable Author Statement</p> <p>Used for information from review articles where the original experiments are traceable through that article and also for information from text books or dictionaries.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#tas">GO evidence code guide</a></p> Traceable author statementi
- induction of bacterial agglutination Source: UniProtKB <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
- innate immune response Source: UniProtKB <p>Traceable Author Statement</p> <p>Used for information from review articles where the original experiments are traceable through that article and also for information from text books or dictionaries.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#tas">GO evidence code guide</a></p> Traceable author statementi
- multicellular organism development Source: UniProtKB-KW
- protein transport Source: UniProtKB-KW
- receptor-mediated endocytosis Source: UniProtKB <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
- viral process Source: UniProtKB-KW
<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi
| Molecular function | Developmental protein |
| Biological process | Antiviral defense, Differentiation, Host-virus interaction, Protein transport, Transport |
Enzyme and pathway databases
Reactome - a knowledgebase of biological pathways and processes More...Reactomei | R-HSA-5683826 Surfactant metabolism |
<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi
| <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi | Recommended name: Deleted in malignant brain tumors 1 proteinAlternative name(s): Glycoprotein 340 Short name: Gp-340 Hensin Salivary agglutinin Short name: SAG Surfactant pulmonary-associated D-binding protein |
| <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi | Name:DMBT1 Synonyms:GP340 |
| <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>Organismi | Homo sapiens (Human) |
| <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri | 9606 [NCBI] |
| <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineagei | cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo |
| <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi |
|
Organism-specific databases
Eukaryotic Pathogen Database Resources More...EuPathDBi | HostDB:ENSG00000187908.15 |
Human Gene Nomenclature Database More...HGNCi | HGNC:2926 DMBT1 |
Online Mendelian Inheritance in Man (OMIM) More...MIMi | 601969 gene |
neXtProt; the human protein knowledge platform More...neXtProti | NX_Q9UGM3 |
<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi
Extracellular region or secreted
- Secreted By similarity
Note: Some isoforms may be membrane-bound. Localized to the lumenal aspect of crypt cells in the small intestine. In the colon, seen in the lumenal aspect of surface epithelial cells. Formed in the ducts of von Ebner gland, and released into the fluid bathing the taste buds contained in the taste papillae (By similarity).By similarity
Extracellular region or secreted
- extracellular exosome Source: UniProtKBInferred from high throughput direct assayi
- extracellular region Source: UniProtKB <p>Traceable Author Statement</p> <p>Used for information from review articles where the original experiments are traceable through that article and also for information from text books or dictionaries.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#tas">GO evidence code guide</a></p> Traceable author statementi
- extracellular space Source: UniProtKBInferred from high throughput direct assayi
Other locations
- cytoplasm Source: UniProtKB <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
- extrinsic component of membrane Source: UniProtKB
- phagocytic vesicle membrane Source: UniProtKB <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
- zymogen granule membrane Source: UniProtKB
<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti
Secreted<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi
<p>This subsection of the ‘Pathology and Biotech’ section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei
Glioma (GLM)
The gene represented in this entry is involved in disease pathogenesis. Homozygous deletions may be the predominant mechanism of DMBT1 inactivation playing a role in carcinogenesis. DMBT1 is deleted in medulloblastoma and glioblastoma cell lines; point mutations have also been reported in patients with glioma. A loss or reduction of DMBT1 expression has been seen in esophageal, gastric, lung and colorectal carcinomas as well.
Disease descriptionGliomas are benign or malignant central nervous system neoplasms derived from glial cells. They comprise astrocytomas and glioblastoma multiforme that are derived from astrocytes, oligodendrogliomas derived from oligodendrocytes and ependymomas derived from ependymocytes.
See also OMIM:137800<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Diseasei
Tumor suppressorOrganism-specific databases
DisGeNET More...DisGeNETi | 1755 |
Online Mendelian Inheritance in Man (OMIM) More...MIMi | 137800 phenotype |
Open Targets More...OpenTargetsi | ENSG00000187908 |
The Pharmacogenetics and Pharmacogenomics Knowledge Base More...PharmGKBi | PA27376 |
Polymorphism and mutation databases
BioMuta curated single-nucleotide variation and disease association database More...BioMutai | DMBT1 |
Domain mapping of disease mutations (DMDM) More...DMDMi | 85687556 |
<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi
Molecule processing
| Feature key | Position(s) | DescriptionActions | Graphical view | Length |
|---|---|---|---|---|
| <p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei | 1 – 19 | Sequence analysisAdd BLAST | 19 | |
| <p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_0000045387 | 20 – 2413 | Deleted in malignant brain tumors 1 proteinAdd BLAST | 2394 |
Amino acid modifications
| Feature key | Position(s) | DescriptionActions | Graphical view | Length |
|---|---|---|---|---|
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 127 ↔ 191 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 140 ↔ 201 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 171 ↔ 181 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 259 ↔ 323 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 272 ↔ 333 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 303 ↔ 313 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 388 ↔ 452 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 401 ↔ 462 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 432 ↔ 442 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 519 ↔ 583 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 532 ↔ 593 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 563 ↔ 573 | By similarity | ||
| <p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi | 566 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 627 ↔ 691 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 640 ↔ 701 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 671 ↔ 681 | By similarity | ||
| <p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi | 737 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 758 ↔ 822 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 771 ↔ 832 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 802 ↔ 812 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 887 ↔ 951 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 900 ↔ 961 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 931 ↔ 941 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 1018 ↔ 1082 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 1031 ↔ 1092 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 1062 ↔ 1072 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 1147 ↔ 1211 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 1160 ↔ 1221 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 1191 ↔ 1201 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 1276 ↔ 1340 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 1289 ↔ 1350 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 1320 ↔ 1330 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 1405 ↔ 1469 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 1418 ↔ 1479 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 1449 ↔ 1459 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 1534 ↔ 1598 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 1547 ↔ 1608 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 1578 ↔ 1588 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 1665 ↔ 1729 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 1678 ↔ 1739 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 1709 ↔ 1719 | By similarity | ||
| <p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi | 1712 | N-linked (GlcNAc...) asparagine1 Publication <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
| 1 | |
| <p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi | 1745 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 1766 ↔ 1792 | By similarity | ||
| <p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi | 1818 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 1819 ↔ 1841 | By similarity | ||
| <p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi | 1832 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
| <p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi | 1842 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
| <p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi | 1889 | N-linked (GlcNAc...) asparagine1 Publication <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
| 1 | |
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 1911 ↔ 1975 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 1924 ↔ 1985 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 1955 ↔ 1965 | By similarity | ||
| <p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi | 1998 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 2008 ↔ 2034 | By similarity | ||
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 2059 ↔ 2081 | By similarity | ||
| <p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi | 2120 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
| <p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi | 2188 | N-linked (GlcNAc...) asparagine1 Publication <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
| 1 | |
| <p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi | 2233 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
| <p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi | 2240 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
| <p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi | 2256 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
| <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi | 2302 ↔ 2360 | By similarity |
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi
Highly N- and O-glycosylated. The O-glycans are heavily sulfated (By similarity).By similarity
<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi
Disulfide bond, GlycoproteinProteomic databases
PaxDb, a database of protein abundance averages across all three domains of life More...PaxDbi | Q9UGM3 |
PeptideAtlas More...PeptideAtlasi | Q9UGM3 |
PRoteomics IDEntifications database More...PRIDEi | Q9UGM3 |
PTM databases
iPTMnet integrated resource for PTMs in systems biology context More...iPTMneti | Q9UGM3 |
Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat. More...PhosphoSitePlusi | Q9UGM3 |
<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni
<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi
Highly expressed in alveolar and macrophage tissues. In some macrophages, expression is seen on the membrane, and in other macrophages, strongly expressed in the phagosome/phagolysosome compartments. Expressed in lung, trachea, salivary gland, small intestine and stomach. In pancreas, expressed in certain cells of the islets of Langerhans. In digestive tract, confined to tissues with large epithelial surfaces. In intestinal tissue, moderately expressed in epithelial cells of the midcrypts and the crypt base. Expression is significantly elevated in intestinal tissue from patients with inflammatory bowel disease (IBD), particularly in surface epithelial and Paneth cells, but not in IBD patients with mutant NOD2. Present in crypt bases of the duodenum, in crypt tops of the colon, and in collecting ducts of the cortical kidney. Expressed in stratified squamous epithelium of vagina and in outer luminar surface and basilar region of columnar epithelial cells in cervix (at protein level). Isoform 1 is secreted to the lumen of the respiratory tract.7 Publications
<p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
- Ref.1"DMBT1, a new member of the SRCR superfamily on chromosome 10q25.3-q26.1 is deleted in malignant brain tumours."
Mollenhauer J., Wiemann S., Scheurlen W., Korn B., Hayashi Y., Wilgenbus K.K., von Deimling A., Poustka A.
Nat. Genet. 17:32-39(1997) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), FUNCTION AS A TUMOR SUPPRESSOR, TISSUE SPECIFICITY, VARIANTS THR-42 AND ALA-60. - Ref.2"Cloning of gp-340, a putative opsonin receptor for lung surfactant protein D."
Holmskov U., Mollenhauer J., Madsen J., Vitved L., Gronlund J., Tornoe I., Kliem A., Reid K.B.M., Poustka A., Skjodt K.
Proc. Natl. Acad. Sci. U.S.A. 96:10794-10799(1999) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION IN MUCOSAL AND CELLULAR IMMUNE DEFENSE, TISSUE SPECIFICITY, SUBCELLULAR LOCATION, DEVELOPMENTAL STAGE, VARIANTS THR-42; LEU-54; ALA-60; MET-649; MET-780 AND SER-856. - Ref.5"Deleted in malignant brain tumors 1 is a versatile mucin-like molecule likely to play a differential role in digestive tract cancer."
Mollenhauer J., Herbertz S., Helmke B., Kollender G., Krebs I., Madsen J., Holmskov U., Sorger K., Schmitt L., Wiemann S., Otto H.F., Grone H.-J., Poustka A.
Cancer Res. 61:8880-8886(2001) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION IN EPITHELIAL DIFFERENTIATION, TISSUE SPECIFICITY, ALTERNATIVE SPLICING, INVOLVEMENT IN ESOPHAGEAL CARCINOMAS, VARIANT SER-856. - Ref.15"DMBT1 encodes a protein involved in the immune defense and in epithelial differentiation and is highly unstable in cancer."
Mollenhauer J., Herbertz S., Holmskov U., Tolnay M., Krebs I., Merlo A., Schroder H.D., Maier D., Breitling F., Wiemann S., Groene H.-J., Poustka A.
Cancer Res. 60:1704-1710(2000) [PubMed] [Europe PMC] [Abstract]Cited for: DEVELOPMENTAL STAGE, TISSUE SPECIFICITY. - Ref.18"The N-terminal SRCR-SID domain of gp-340 interacts with HIV type 1 gp120 sequences and inhibits viral infection."
Wu Z., Lee S., Abrams W., Weissman D., Malamud D.
AIDS Res. Hum. Retroviruses 22:508-515(2006) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, INTERACTION WITH HIV-1 GP120, TISSUE SPECIFICITY. - Ref.20"DMBT1 confers mucosal protection in vivo and a deletion variant is associated with Crohn's disease."
Renner M., Bergmann G., Krebs I., End C., Lyer S., Hilberg F., Helmke B., Gassler N., Autschbach F., Bikker F., Strobel-Freidekind O., Gronert-Sum S., Benner A., Blaich S., Wittig R., Hudler M., Ligtenberg A.J., Madsen J. , Holmskov U., Annese V., Latiano A., Schirmacher P., Amerongen A.V.N., D'Amato M., Kioschis P., Hafner M., Poustka A., Mollenhauer J.
Gastroenterology 133:1499-1509(2007) [PubMed] [Europe PMC] [Abstract]Cited for: TISSUE SPECIFICITY. - Ref.21"Regulation of DMBT1 via NOD2 and TLR4 in intestinal epithelial cells modulates bacterial recognition and invasion."
Rosenstiel P., Sina C., End C., Renner M., Lyer S., Till A., Hellmig S., Nikolaus S., Foelsch U.R., Helmke B., Autschbach F., Schirmacher P., Kioschis P., Hafner M., Poustka A., Mollenhauer J., Schreiber S.
J. Immunol. 178:8203-8211(2007) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, TISSUE SPECIFICITY, INDUCTION.
<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei
Expressed in fetal lung, intestine and skin. Secreted to the extracellular matrix (ECM) in certain fetal epithelia.2 Publications
<p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
- Ref.2"Cloning of gp-340, a putative opsonin receptor for lung surfactant protein D."
Holmskov U., Mollenhauer J., Madsen J., Vitved L., Gronlund J., Tornoe I., Kliem A., Reid K.B.M., Poustka A., Skjodt K.
Proc. Natl. Acad. Sci. U.S.A. 96:10794-10799(1999) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION IN MUCOSAL AND CELLULAR IMMUNE DEFENSE, TISSUE SPECIFICITY, SUBCELLULAR LOCATION, DEVELOPMENTAL STAGE, VARIANTS THR-42; LEU-54; ALA-60; MET-649; MET-780 AND SER-856. - Ref.15"DMBT1 encodes a protein involved in the immune defense and in epithelial differentiation and is highly unstable in cancer."
Mollenhauer J., Herbertz S., Holmskov U., Tolnay M., Krebs I., Merlo A., Schroder H.D., Maier D., Breitling F., Wiemann S., Groene H.-J., Poustka A.
Cancer Res. 60:1704-1710(2000) [PubMed] [Europe PMC] [Abstract]Cited for: DEVELOPMENTAL STAGE, TISSUE SPECIFICITY.
<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni
Up-regulated in intestinal epithelial cells in response to proinflammatory stimuli including TNF and bacterial lipopolysaccharides (LPS).1 Publication
<p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
- Ref.21"Regulation of DMBT1 via NOD2 and TLR4 in intestinal epithelial cells modulates bacterial recognition and invasion."
Rosenstiel P., Sina C., End C., Renner M., Lyer S., Till A., Hellmig S., Nikolaus S., Foelsch U.R., Helmke B., Autschbach F., Schirmacher P., Kioschis P., Hafner M., Poustka A., Mollenhauer J., Schreiber S.
J. Immunol. 178:8203-8211(2007) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, TISSUE SPECIFICITY, INDUCTION.
Gene expression databases
Bgee dataBase for Gene Expression Evolution More...Bgeei | ENSG00000187908 |
Genevisible search portal to normalized and curated expression data from Genevestigator More...Genevisiblei | Q9UGM3 HS |
Organism-specific databases
Human Protein Atlas More...HPAi | HPA040778 |
<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni
<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei
Interacts with LGALS3 (By similarity). Binds SFTPD and SPAR in a calcium-dependent manner. Binds to HIV-1 glycoprotein 120.By similarity3 Publications
<p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
- Ref.12"Isolation and characterization of a new member of the scavenger receptor superfamily, glycoprotein-340 (gp-340), as a lung surfactant protein-D binding molecule."
Holmskov U., Lawson P., Teisner B., Tornoe I., Willis A.C., Morgan C., Koch C., Reid K.B.
J. Biol. Chem. 272:13743-13749(1997) [PubMed] [Europe PMC] [Abstract]Cited for: INTERACTION WITH SFTPD. - Ref.13"Glycoprotein-340 binds surfactant protein-A (SP-A) and stimulates alveolar macrophage migration in an SP-A-independent manner."
Tino M.J., Wright J.R.
Am. J. Respir. Cell Mol. Biol. 20:759-768(1999) [PubMed] [Europe PMC] [Abstract]Cited for: INTERACTION WITH SPAR. - Ref.18"The N-terminal SRCR-SID domain of gp-340 interacts with HIV type 1 gp120 sequences and inhibits viral infection."
Wu Z., Lee S., Abrams W., Weissman D., Malamud D.
AIDS Res. Hum. Retroviruses 22:508-515(2006) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, INTERACTION WITH HIV-1 GP120, TISSUE SPECIFICITY.
<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi
| With | Entry | #Exp. | IntAct | Notes |
|---|---|---|---|---|
| SFTPA1 | Q8IWL2 | 2 | EBI-1044970,EBI-11316418 |
<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni
- calcium-dependent protein binding Source: UniProtKB <p>Traceable Author Statement</p> <p>Used for information from review articles where the original experiments are traceable through that article and also for information from text books or dictionaries.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#tas">GO evidence code guide</a></p> Traceable author statementi
- zymogen binding Source: UniProtKB
Protein-protein interaction databases
The Biological General Repository for Interaction Datasets (BioGrid) More...BioGridi | 108095, 17 interactors |
Database of interacting proteins More...DIPi | DIP-50763N |
Protein interaction database and analysis system More...IntActi | Q9UGM3, 7 interactors |
STRING: functional protein association networks More...STRINGi | 9606.ENSP00000357905 |
<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei
3D structure databases
Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase More...ProteinModelPortali | Q9UGM3 |
SWISS-MODEL Repository - a database of annotated 3D protein structure models More...SMRi | Q9UGM3 |
Database of comparative protein structure models More...ModBasei | Search... |
MobiDB: a database of protein disorder and mobility annotations More...MobiDBi | Search... |
<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi
Domains and Repeats
| Feature key | Position(s) | DescriptionActions | Graphical view | Length |
|---|---|---|---|---|
| <p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini | 102 – 202 | SRCR 1PROSITE-ProRule annotation <p>Manual validated information which has been generated by the UniProtKB automatic annotation system.</p> <p><a href="/manual/evidences#ECO:0000255">More...</a></p> Manual assertion according to rulesi Add BLAST | 101 | |
| <p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini | 234 – 334 | SRCR 2PROSITE-ProRule annotation <p>Manual validated information which has been generated by the UniProtKB automatic annotation system.</p> <p><a href="/manual/evidences#ECO:0000255">More...</a></p> Manual assertion according to rulesi Add BLAST | 101 | |
| <p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini | 363 – 463 | SRCR 3PROSITE-ProRule annotation <p>Manual validated information which has been generated by the UniProtKB automatic annotation system.</p> <p><a href="/manual/evidences#ECO:0000255">More...</a></p> Manual assertion according to rulesi Add BLAST | 101 | |
| <p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini | 494 – 594 | SRCR 4PROSITE-ProRule annotation <p>Manual validated information which has been generated by the UniProtKB automatic annotation system.</p> <p><a href="/manual/evidences#ECO:0000255">More...</a></p> Manual assertion according to rulesi Add BLAST | 101 | |
| <p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini | 602 – 702 | SRCR 5PROSITE-ProRule annotation <p>Manual validated information which has been generated by the UniProtKB automatic annotation system.</p> <p><a href="/manual/evidences#ECO:0000255">More...</a></p> Manual assertion according to rulesi Add BLAST | 101 | |
| <p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini | 733 – 833 | SRCR 6PROSITE-ProRule annotation <p>Manual validated information which has been generated by the UniProtKB automatic annotation system.</p> <p><a href="/manual/evidences#ECO:0000255">More...</a></p> Manual assertion according to rulesi Add BLAST | 101 | |
| <p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini | 862 – 962 | SRCR 7PROSITE-ProRule annotation <p>Manual validated information which has been generated by the UniProtKB automatic annotation system.</p> <p><a href="/manual/evidences#ECO:0000255">More...</a></p> Manual assertion according to rulesi Add BLAST | 101 | |
| <p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini | 993 – 1093 | SRCR 8PROSITE-ProRule annotation <p>Manual validated information which has been generated by the UniProtKB automatic annotation system.</p> <p><a href="/manual/evidences#ECO:0000255">More...</a></p> Manual assertion according to rulesi Add BLAST | 101 | |
| <p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini | 1122 – 1222 | SRCR 9PROSITE-ProRule annotation <p>Manual validated information which has been generated by the UniProtKB automatic annotation system.</p> <p><a href="/manual/evidences#ECO:0000255">More...</a></p> Manual assertion according to rulesi Add BLAST | 101 | |
| <p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini | 1251 – 1351 | SRCR 10PROSITE-ProRule annotation <p>Manual validated information which has been generated by the UniProtKB automatic annotation system.</p> <p><a href="/manual/evidences#ECO:0000255">More...</a></p> Manual assertion according to rulesi Add BLAST | 101 | |
| <p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini | 1380 – 1480 | SRCR 11PROSITE-ProRule annotation <p>Manual validated information which has been generated by the UniProtKB automatic annotation system.</p> <p><a href="/manual/evidences#ECO:0000255">More...</a></p> Manual assertion according to rulesi Add BLAST | 101 | |
| <p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini | 1509 – 1609 | SRCR 12PROSITE-ProRule annotation <p>Manual validated information which has been generated by the UniProtKB automatic annotation system.</p> <p><a href="/manual/evidences#ECO:0000255">More...</a></p> Manual assertion according to rulesi Add BLAST | 101 | |
| <p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini | 1640 – 1740 | SRCR 13PROSITE-ProRule annotation <p>Manual validated information which has been generated by the UniProtKB automatic annotation system.</p> <p><a href="/manual/evidences#ECO:0000255">More...</a></p> Manual assertion according to rulesi Add BLAST | 101 | |
| <p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini | 1766 – 1877 | CUB 1PROSITE-ProRule annotation <p>Manual validated information which has been generated by the UniProtKB automatic annotation system.</p> <p><a href="/manual/evidences#ECO:0000255">More...</a></p> Manual assertion according to rulesi Add BLAST | 112 | |
| <p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini | 1883 – 1986 | SRCR 14PROSITE-ProRule annotation <p>Manual validated information which has been generated by the UniProtKB automatic annotation system.</p> <p><a href="/manual/evidences#ECO:0000255">More...</a></p> Manual assertion according to rulesi Add BLAST | 104 | |
| <p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini | 2008 – 2117 | CUB 2PROSITE-ProRule annotation <p>Manual validated information which has been generated by the UniProtKB automatic annotation system.</p> <p><a href="/manual/evidences#ECO:0000255">More...</a></p> Manual assertion according to rulesi Add BLAST | 110 | |
| <p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini | 2126 – 2381 | ZPPROSITE-ProRule annotation <p>Manual validated information which has been generated by the UniProtKB automatic annotation system.</p> <p><a href="/manual/evidences#ECO:0000255">More...</a></p> Manual assertion according to rulesi Add BLAST | 256 |
Compositional bias
| Feature key | Position(s) | DescriptionActions | Graphical view | Length |
|---|---|---|---|---|
| <p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi | 1755 – 1759 | Poly-Thr | 5 |
<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini
The SRCR domains mediate binding to bacteria. The minimal bacterial-binding site is an 11-residue repeat of GRVEVLYRGSW where VEVL and W are critical residues.
<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi
Belongs to the DMBT1 family.Curated
<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini
Repeat, SignalPhylogenomic databases
evolutionary genealogy of genes: Non-supervised Orthologous Groups More...eggNOGi | ENOG410IHBC Eukaryota ENOG410XQVR LUCA |
Ensembl GeneTree More...GeneTreei | ENSGT00900000140803 |
The HOVERGEN Database of Homologous Vertebrate Genes More...HOVERGENi | HBG060122 |
InParanoid: Eukaryotic Ortholog Groups More...InParanoidi | Q9UGM3 |
KEGG Orthology (KO) More...KOi | K13912 |
Identification of Orthologs from Complete Genome Data More...OMAi | NTHNCGH |
Database of Orthologous Groups More...OrthoDBi | EOG091G0DF7 |
Database for complete collections of gene phylogenies More...PhylomeDBi | Q9UGM3 |
TreeFam database of animal gene trees More...TreeFami | TF329295 |
Family and domain databases
Conserved Domains Database More...CDDi | cd00041 CUB, 2 hits |
Gene3D Structural and Functional Annotation of Protein Families More...Gene3Di | 2.60.120.290, 2 hits 3.10.250.10, 14 hits |
Integrated resource of protein families, domains and functional sites More...InterProi | View protein in InterPro IPR000859 CUB_dom IPR035914 Sperma_CUB_dom_sf IPR001190 SRCR IPR017448 SRCR-like_dom IPR036772 SRCR-like_dom_sf IPR001507 ZP_dom IPR017977 ZP_dom_CS |
Pfam protein domain database More...Pfami | View protein in Pfam PF00431 CUB, 2 hits PF00530 SRCR, 14 hits PF00100 Zona_pellucida, 1 hit |
Protein Motif fingerprint database; a protein domain database More...PRINTSi | PR00258 SPERACTRCPTR |
Simple Modular Architecture Research Tool; a protein domain database More...SMARTi | View protein in SMART SM00042 CUB, 2 hits SM00202 SR, 14 hits SM00241 ZP, 1 hit |
Superfamily database of structural and functional annotation More...SUPFAMi | SSF49854 SSF49854, 2 hits SSF56487 SSF56487, 14 hits |
PROSITE; a protein domain and family database More...PROSITEi | View protein in PROSITE PS01180 CUB, 2 hits PS00420 SRCR_1, 13 hits PS50287 SRCR_2, 14 hits PS00682 ZP_1, 1 hit PS51034 ZP_2, 1 hit |
<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (9)i
<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.
<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.
This entry describes 9 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basketAdded to basket
Note: More isoforms may exist.
Isoform 1 (identifier: Q9UGM3-1) [UniParc]FASTAAdd to basketAdded to basketShow »
Also known as: DMBT1/8kb.2
This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
10 20 30 40 50
MGISTVILEM CLLWGQVLST GGWIPRTTDY ASLIPSEVPL DPTVAEGSPF
60 70 80 90 100
PSESTLESTV AEGSPISLES TLESTVAEGS LIPSESTLES TVAEGSDSGL
110 120 130 140 150
ALRLVNGDGR CQGRVEILYR GSWGTVCDDS WDTNDANVVC RQLGCGWAMS
160 170 180 190 200
APGNAWFGQG SGPIALDDVR CSGHESYLWS CPHNGWLSHN CGHGEDAGVI
210 220 230 240 250
CSAAQPQSTL RPESWPVRIS PPVPTEGSES SLALRLVNGG DRCRGRVEVL
260 270 280 290 300
YRGSWGTVCD DYWDTNDANV VCRQLGCGWA MSAPGNAQFG QGSGPIVLDD
310 320 330 340 350
VRCSGHESYL WSCPHNGWLT HNCGHSEDAG VICSAPQSRP TPSPDTWPTS
360 370 380 390 400
HASTAGPESS LALRLVNGGD RCQGRVEVLY RGSWGTVCDD SWDTSDANVV
410 420 430 440 450
CRQLGCGWAT SAPGNARFGQ GSGPIVLDDV RCSGYESYLW SCPHNGWLSH
460 470 480 490 500
NCQHSEDAGV ICSAAHSWST PSPDTLPTIT LPASTVGSES SLALRLVNGG
510 520 530 540 550
DRCQGRVEVL YRGSWGTVCD DSWDTNDANV VCRQLGCGWA MLAPGNARFG
560 570 580 590 600
QGSGPIVLDD VRCSGNESYL WSCPHNGWLS HNCGHSEDAG VICSGPESSL
610 620 630 640 650
ALRLVNGGDR CQGRVEVLYR GSWGTVCDDS WDTNDANVVC RQLGCGWATS
660 670 680 690 700
APGNARFGQG SGPIVLDDVR CSGHESYLWS CPNNGWLSHN CGHHEDAGVI
710 720 730 740 750
CSAAQSRSTP RPDTLSTITL PPSTVGSESS LTLRLVNGSD RCQGRVEVLY
760 770 780 790 800
RGSWGTVCDD SWDTNDANVV CRQLGCGWAT SAPGNARFGQ GSGPIVLDDV
810 820 830 840 850
RCSGHESYLW SCPHNGWLSH NCGHHEDAGV ICSVSQSRPT PSPDTWPTSH
860 870 880 890 900
ASTAGPESSL ALRLVNGGDR CQGRVEVLYR GSWGTVCDDS WDTSDANVVC
910 920 930 940 950
RQLGCGWATS APGNARFGQG SGPIVLDDVR CSGYESYLWS CPHNGWLSHN
960 970 980 990 1000
CQHSEDAGVI CSAAHSWSTP SPDTLPTITL PASTVGSESS LALRLVNGGD
1010 1020 1030 1040 1050
RCQGRVEVLY QGSWGTVCDD SWDTNDANVV CRQLGCGWAM SAPGNARFGQ
1060 1070 1080 1090 1100
GSGPIVLDDV RCSGHESYLW SCPHNGWLSH NCGHSEDAGV ICSASQSRPT
1110 1120 1130 1140 1150
PSPDTWPTSH ASTAGSESSL ALRLVNGGDR CQGRVEVLYR GSWGTVCDDY
1160 1170 1180 1190 1200
WDTNDANVVC RQLGCGWAMS APGNARFGQG SGPIVLDDVR CSGHESYLWS
1210 1220 1230 1240 1250
CPHNGWLSHN CGHHEDAGVI CSASQSQPTP SPDTWPTSHA STAGSESSLA
1260 1270 1280 1290 1300
LRLVNGGDRC QGRVEVLYRG SWGTVCDDYW DTNDANVVCR QLGCGWATSA
1310 1320 1330 1340 1350
PGNARFGQGS GPIVLDDVRC SGHESYLWSC PHNGWLSHNC GHHEDAGVIC
1360 1370 1380 1390 1400
SASQSQPTPS PDTWPTSHAS TAGSESSLAL RLVNGGDRCQ GRVEVLYRGS
1410 1420 1430 1440 1450
WGTVCDDYWD TNDANVVCRQ LGCGWATSAP GNARFGQGSG PIVLDDVRCS
1460 1470 1480 1490 1500
GHESYLWSCP HNGWLSHNCG HHEDAGVICS ASQSQPTPSP DTWPTSRAST
1510 1520 1530 1540 1550
AGSESTLALR LVNGGDRCRG RVEVLYQGSW GTVCDDYWDT NDANVVCRQL
1560 1570 1580 1590 1600
GCGWAMSAPG NAQFGQGSGP IVLDDVRCSG HESYLWSCPH NGWLSHNCGH
1610 1620 1630 1640 1650
HEDAGVICSA AQSQSTPRPD TWLTTNLPAL TVGSESSLAL RLVNGGDRCR
1660 1670 1680 1690 1700
GRVEVLYRGS WGTVCDDSWD TNDANVVCRQ LGCGWAMSAP GNARFGQGSG
1710 1720 1730 1740 1750
PIVLDDVRCS GNESYLWSCP HKGWLTHNCG HHEDAGVICS ATQINSTTTD
1760 1770 1780 1790 1800
WWHPTTTTTA RPSSNCGGFL FYASGTFSSP SYPAYYPNNA KCVWEIEVNS
1810 1820 1830 1840 1850
GYRINLGFSN LKLEAHHNCS FDYVEIFDGS LNSSLLLGKI CNDTRQIFTS
1860 1870 1880 1890 1900
SYNRMTIHFR SDISFQNTGF LAWYNSFPSD ATLRLVNLNS SYGLCAGRVE
1910 1920 1930 1940 1950
IYHGGTWGTV CDDSWTIQEA EVVCRQLGCG RAVSALGNAY FGSGSGPITL
1960 1970 1980 1990 2000
DDVECSGTES TLWQCRNRGW FSHNCNHRED AGVICSGNHL STPAPFLNIT
2010 2020 2030 2040 2050
RPNTDYSCGG FLSQPSGDFS SPFYPGNYPN NAKCVWDIEV QNNYRVTVIF
2060 2070 2080 2090 2100
RDVQLEGGCN YDYIEVFDGP YRSSPLIARV CDGARGSFTS SSNFMSIRFI
2110 2120 2130 2140 2150
SDHSITRRGF RAEYYSSPSN DSTNLLCLPN HMQASVSRSY LQSLGFSASD
2160 2170 2180 2190 2200
LVISTWNGYY ECRPQITPNL VIFTIPYSGC GTFKQADNDT IDYSNFLTAA
2210 2220 2230 2240 2250
VSGGIIKRRT DLRIHVSCRM LQNTWVDTMY IANDTIHVAN NTIQVEEVQY
2260 2270 2280 2290 2300
GNFDVNISFY TSSSFLYPVT SRPYYVDLNQ DLYVQAEILH SDAVLTLFVD
2310 2320 2330 2340 2350
TCVASPYSND FTSLTYDLIR SGCVRDDTYG PYSSPSLRIA RFRFRAFHFL
2360 2370 2380 2390 2400
NRFPSVYLRC KMVVCRAYDP SSRCYRGCVL RSKRDVGSYQ EKVDVVLGPI
2410
QLQTPPRREE EPR
Length:2,413
Mass (Da):260,735
Last modified:January 10, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated
from the sequence. It is useful for tracking sequence updates.</p>
<p>It should be noted that while, in theory, two different sequences could
have the same checksum value, the likelihood that this would happen
is extremely low.</p>
<p>However UniProtKB may contain entries with identical sequences in case
of multiple genes (paralogs).</p>
<p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64)
using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1.
The algorithm is described in the ISO 3309 standard.
</p>
<p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br />
<strong>Cyclic redundancy and other checksums</strong><br />
<a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p>
Checksum:i25363E6263234F15
Isoform 2 (identifier: Q9UGM3-2) [UniParc]FASTAAdd to basketAdded to basketShow »
Also known as: DMBT1/6kb.1
The sequence of this isoform differs from the canonical sequence as follows:
337-835: Missing.
1170-1298: Missing.
10 20 30 40 50
MGISTVILEM CLLWGQVLST GGWIPRTTDY ASLIPSEVPL DPTVAEGSPF
60 70 80 90 100
PSESTLESTV AEGSPISLES TLESTVAEGS LIPSESTLES TVAEGSDSGL
110 120 130 140 150
ALRLVNGDGR CQGRVEILYR GSWGTVCDDS WDTNDANVVC RQLGCGWAMS
160 170 180 190 200
APGNAWFGQG SGPIALDDVR CSGHESYLWS CPHNGWLSHN CGHGEDAGVI
210 220 230 240 250
CSAAQPQSTL RPESWPVRIS PPVPTEGSES SLALRLVNGG DRCRGRVEVL
260 270 280 290 300
YRGSWGTVCD DYWDTNDANV VCRQLGCGWA MSAPGNAQFG QGSGPIVLDD
310 320 330 340 350
VRCSGHESYL WSCPHNGWLT HNCGHSEDAG VICSAPQSRP TPSPDTWPTS
360 370 380 390 400
HASTAGPESS LALRLVNGGD RCQGRVEVLY RGSWGTVCDD SWDTSDANVV
410 420 430 440 450
CRQLGCGWAT SAPGNARFGQ GSGPIVLDDV RCSGYESYLW SCPHNGWLSH
460 470 480 490 500
NCQHSEDAGV ICSAAHSWST PSPDTLPTIT LPASTVGSES SLALRLVNGG
510 520 530 540 550
DRCQGRVEVL YQGSWGTVCD DSWDTNDANV VCRQLGCGWA MSAPGNARFG
560 570 580 590 600
QGSGPIVLDD VRCSGHESYL WSCPHNGWLS HNCGHSEDAG VICSASQSRP
610 620 630 640 650
TPSPDTWPTS HASTAGSESS LALRLVNGGD RCQGRVEVLY RGSWGTVCDD
660 670 680 690 700
YWDTNDANVV CRQLGCGWAM SAPGNARFGQ GSGPIVLDDV RCSGHESYLW
710 720 730 740 750
SCPHNGWLSH NCGHHEDAGV ICSASQSQPT PSPDTWPTSH ASTAGSESSL
760 770 780 790 800
ALRLVNGGDR CQGRVEVLYR GSWGTVCDDY WDTNDANVVC RQLGCGWATS
810 820 830 840 850
APGNARFGQG SGPIVLDDVR CSGHESYLWS CPHNGWLSHN CGHHEDAGVI
860 870 880 890 900
CSASQSQPTP SPDTWPTSRA STAGSESTLA LRLVNGGDRC RGRVEVLYQG
910 920 930 940 950
SWGTVCDDYW DTNDANVVCR QLGCGWAMSA PGNAQFGQGS GPIVLDDVRC
960 970 980 990 1000
SGHESYLWSC PHNGWLSHNC GHHEDAGVIC SAAQSQSTPR PDTWLTTNLP
1010 1020 1030 1040 1050
ALTVGSESSL ALRLVNGGDR CRGRVEVLYR GSWGTVCDDS WDTNDANVVC
1060 1070 1080 1090 1100
RQLGCGWAMS APGNARFGQG SGPIVLDDVR CSGNESYLWS CPHKGWLTHN
1110 1120 1130 1140 1150
CGHHEDAGVI CSATQINSTT TDWWHPTTTT TARPSSNCGG FLFYASGTFS
1160 1170 1180 1190 1200
SPSYPAYYPN NAKCVWEIEV NSGYRINLGF SNLKLEAHHN CSFDYVEIFD
1210 1220 1230 1240 1250
GSLNSSLLLG KICNDTRQIF TSSYNRMTIH FRSDISFQNT GFLAWYNSFP
1260 1270 1280 1290 1300
SDATLRLVNL NSSYGLCAGR VEIYHGGTWG TVCDDSWTIQ EAEVVCRQLG
1310 1320 1330 1340 1350
CGRAVSALGN AYFGSGSGPI TLDDVECSGT ESTLWQCRNR GWFSHNCNHR
1360 1370 1380 1390 1400
EDAGVICSGN HLSTPAPFLN ITRPNTDYSC GGFLSQPSGD FSSPFYPGNY
1410 1420 1430 1440 1450
PNNAKCVWDI EVQNNYRVTV IFRDVQLEGG CNYDYIEVFD GPYRSSPLIA
1460 1470 1480 1490 1500
RVCDGARGSF TSSSNFMSIR FISDHSITRR GFRAEYYSSP SNDSTNLLCL
1510 1520 1530 1540 1550
PNHMQASVSR SYLQSLGFSA SDLVISTWNG YYECRPQITP NLVIFTIPYS
1560 1570 1580 1590 1600
GCGTFKQADN DTIDYSNFLT AAVSGGIIKR RTDLRIHVSC RMLQNTWVDT
1610 1620 1630 1640 1650
MYIANDTIHV ANNTIQVEEV QYGNFDVNIS FYTSSSFLYP VTSRPYYVDL
1660 1670 1680 1690 1700
NQDLYVQAEI LHSDAVLTLF VDTCVASPYS NDFTSLTYDL IRSGCVRDDT
1710 1720 1730 1740 1750
YGPYSSPSLR IARFRFRAFH FLNRFPSVYL RCKMVVCRAY DPSSRCYRGC
1760 1770 1780
VLRSKRDVGS YQEKVDVVLG PIQLQTPPRR EEEPR
Length:1,785
Mass (Da):193,971
<p>The checksum is a form of redundancy check that is calculated
from the sequence. It is useful for tracking sequence updates.</p>
<p>It should be noted that while, in theory, two different sequences could
have the same checksum value, the likelihood that this would happen
is extremely low.</p>
<p>However UniProtKB may contain entries with identical sequences in case
of multiple genes (paralogs).</p>
<p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64)
using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1.
The algorithm is described in the ISO 3309 standard.
</p>
<p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br />
<strong>Cyclic redundancy and other checksums</strong><br />
<a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p>
Checksum:iA01C68AF13C478BB
Isoform 3 (identifier: Q9UGM3-3) [UniParc]FASTAAdd to basketAdded to basketShow »
Also known as: DMBT1/8kb.1
The sequence of this isoform differs from the canonical sequence as follows:
464-473: Missing.
10 20 30 40 50
MGISTVILEM CLLWGQVLST GGWIPRTTDY ASLIPSEVPL DPTVAEGSPF
60 70 80 90 100
PSESTLESTV AEGSPISLES TLESTVAEGS LIPSESTLES TVAEGSDSGL
110 120 130 140 150
ALRLVNGDGR CQGRVEILYR GSWGTVCDDS WDTNDANVVC RQLGCGWAMS
160 170 180 190 200
APGNAWFGQG SGPIALDDVR CSGHESYLWS CPHNGWLSHN CGHGEDAGVI
210 220 230 240 250
CSAAQPQSTL RPESWPVRIS PPVPTEGSES SLALRLVNGG DRCRGRVEVL
260 270 280 290 300
YRGSWGTVCD DYWDTNDANV VCRQLGCGWA MSAPGNAQFG QGSGPIVLDD
310 320 330 340 350
VRCSGHESYL WSCPHNGWLT HNCGHSEDAG VICSAPQSRP TPSPDTWPTS
360 370 380 390 400
HASTAGPESS LALRLVNGGD RCQGRVEVLY RGSWGTVCDD SWDTSDANVV
410 420 430 440 450
CRQLGCGWAT SAPGNARFGQ GSGPIVLDDV RCSGYESYLW SCPHNGWLSH
460 470 480 490 500
NCQHSEDAGV ICSDTLPTIT LPASTVGSES SLALRLVNGG DRCQGRVEVL
510 520 530 540 550
YRGSWGTVCD DSWDTNDANV VCRQLGCGWA MLAPGNARFG QGSGPIVLDD
560 570 580 590 600
VRCSGNESYL WSCPHNGWLS HNCGHSEDAG VICSGPESSL ALRLVNGGDR
610 620 630 640 650
CQGRVEVLYR GSWGTVCDDS WDTNDANVVC RQLGCGWATS APGNARFGQG
660 670 680 690 700
SGPIVLDDVR CSGHESYLWS CPNNGWLSHN CGHHEDAGVI CSAAQSRSTP
710 720 730 740 750
RPDTLSTITL PPSTVGSESS LTLRLVNGSD RCQGRVEVLY RGSWGTVCDD
760 770 780 790 800
SWDTNDANVV CRQLGCGWAT SAPGNARFGQ GSGPIVLDDV RCSGHESYLW
810 820 830 840 850
SCPHNGWLSH NCGHHEDAGV ICSVSQSRPT PSPDTWPTSH ASTAGPESSL
860 870 880 890 900
ALRLVNGGDR CQGRVEVLYR GSWGTVCDDS WDTSDANVVC RQLGCGWATS
910 920 930 940 950
APGNARFGQG SGPIVLDDVR CSGYESYLWS CPHNGWLSHN CQHSEDAGVI
960 970 980 990 1000
CSAAHSWSTP SPDTLPTITL PASTVGSESS LALRLVNGGD RCQGRVEVLY
1010 1020 1030 1040 1050
QGSWGTVCDD SWDTNDANVV CRQLGCGWAM SAPGNARFGQ GSGPIVLDDV
1060 1070 1080 1090 1100
RCSGHESYLW SCPHNGWLSH NCGHSEDAGV ICSASQSRPT PSPDTWPTSH
1110 1120 1130 1140 1150
ASTAGSESSL ALRLVNGGDR CQGRVEVLYR GSWGTVCDDY WDTNDANVVC
1160 1170 1180 1190 1200
RQLGCGWAMS APGNARFGQG SGPIVLDDVR CSGHESYLWS CPHNGWLSHN
1210 1220 1230 1240 1250
CGHHEDAGVI CSASQSQPTP SPDTWPTSHA STAGSESSLA LRLVNGGDRC
1260 1270 1280 1290 1300
QGRVEVLYRG SWGTVCDDYW DTNDANVVCR QLGCGWATSA PGNARFGQGS
1310 1320 1330 1340 1350
GPIVLDDVRC SGHESYLWSC PHNGWLSHNC GHHEDAGVIC SASQSQPTPS
1360 1370 1380 1390 1400
PDTWPTSHAS TAGSESSLAL RLVNGGDRCQ GRVEVLYRGS WGTVCDDYWD
1410 1420 1430 1440 1450
TNDANVVCRQ LGCGWATSAP GNARFGQGSG PIVLDDVRCS GHESYLWSCP
1460 1470 1480 1490 1500
HNGWLSHNCG HHEDAGVICS ASQSQPTPSP DTWPTSRAST AGSESTLALR
1510 1520 1530 1540 1550
LVNGGDRCRG RVEVLYQGSW GTVCDDYWDT NDANVVCRQL GCGWAMSAPG
1560 1570 1580 1590 1600
NAQFGQGSGP IVLDDVRCSG HESYLWSCPH NGWLSHNCGH HEDAGVICSA
1610 1620 1630 1640 1650
AQSQSTPRPD TWLTTNLPAL TVGSESSLAL RLVNGGDRCR GRVEVLYRGS
1660 1670 1680 1690 1700
WGTVCDDSWD TNDANVVCRQ LGCGWAMSAP GNARFGQGSG PIVLDDVRCS
1710 1720 1730 1740 1750
GNESYLWSCP HKGWLTHNCG HHEDAGVICS ATQINSTTTD WWHPTTTTTA
1760 1770 1780 1790 1800
RPSSNCGGFL FYASGTFSSP SYPAYYPNNA KCVWEIEVNS GYRINLGFSN
1810 1820 1830 1840 1850
LKLEAHHNCS FDYVEIFDGS LNSSLLLGKI CNDTRQIFTS SYNRMTIHFR
1860 1870 1880 1890 1900
SDISFQNTGF LAWYNSFPSD ATLRLVNLNS SYGLCAGRVE IYHGGTWGTV
1910 1920 1930 1940 1950
CDDSWTIQEA EVVCRQLGCG RAVSALGNAY FGSGSGPITL DDVECSGTES
1960 1970 1980 1990 2000
TLWQCRNRGW FSHNCNHRED AGVICSGNHL STPAPFLNIT RPNTDYSCGG
2010 2020 2030 2040 2050
FLSQPSGDFS SPFYPGNYPN NAKCVWDIEV QNNYRVTVIF RDVQLEGGCN
2060 2070 2080 2090 2100
YDYIEVFDGP YRSSPLIARV CDGARGSFTS SSNFMSIRFI SDHSITRRGF
2110 2120 2130 2140 2150
RAEYYSSPSN DSTNLLCLPN HMQASVSRSY LQSLGFSASD LVISTWNGYY
2160 2170 2180 2190 2200
ECRPQITPNL VIFTIPYSGC GTFKQADNDT IDYSNFLTAA VSGGIIKRRT
2210 2220 2230 2240 2250
DLRIHVSCRM LQNTWVDTMY IANDTIHVAN NTIQVEEVQY GNFDVNISFY
2260 2270 2280 2290 2300
TSSSFLYPVT SRPYYVDLNQ DLYVQAEILH SDAVLTLFVD TCVASPYSND
2310 2320 2330 2340 2350
FTSLTYDLIR SGCVRDDTYG PYSSPSLRIA RFRFRAFHFL NRFPSVYLRC
2360 2370 2380 2390 2400
KMVVCRAYDP SSRCYRGCVL RSKRDVGSYQ EKVDVVLGPI QLQTPPRREE
EPR
Length:2,403
Mass (Da):259,713
<p>The checksum is a form of redundancy check that is calculated
from the sequence. It is useful for tracking sequence updates.</p>
<p>It should be noted that while, in theory, two different sequences could
have the same checksum value, the likelihood that this would happen
is extremely low.</p>
<p>However UniProtKB may contain entries with identical sequences in case
of multiple genes (paralogs).</p>
<p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64)
using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1.
The algorithm is described in the ISO 3309 standard.
</p>
<p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br />
<strong>Cyclic redundancy and other checksums</strong><br />
<a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p>
Checksum:iC46A2BD09B2C874D
Isoform 4 (identifier: Q9UGM3-4) [UniParc]FASTAAdd to basketAdded to basket
The sequence of this isoform differs from the canonical sequence as follows:
523-1408: Missing.
10 20 30 40 50
MGISTVILEM CLLWGQVLST GGWIPRTTDY ASLIPSEVPL DPTVAEGSPF
60 70 80 90 100
PSESTLESTV AEGSPISLES TLESTVAEGS LIPSESTLES TVAEGSDSGL
110 120 130 140 150
ALRLVNGDGR CQGRVEILYR GSWGTVCDDS WDTNDANVVC RQLGCGWAMS
160 170 180 190 200
APGNAWFGQG SGPIALDDVR CSGHESYLWS CPHNGWLSHN CGHGEDAGVI
210 220 230 240 250
CSAAQPQSTL RPESWPVRIS PPVPTEGSES SLALRLVNGG DRCRGRVEVL
260 270 280 290 300
YRGSWGTVCD DYWDTNDANV VCRQLGCGWA MSAPGNAQFG QGSGPIVLDD
310 320 330 340 350
VRCSGHESYL WSCPHNGWLT HNCGHSEDAG VICSAPQSRP TPSPDTWPTS
360 370 380 390 400
HASTAGPESS LALRLVNGGD RCQGRVEVLY RGSWGTVCDD SWDTSDANVV
410 420 430 440 450
CRQLGCGWAT SAPGNARFGQ GSGPIVLDDV RCSGYESYLW SCPHNGWLSH
460 470 480 490 500
NCQHSEDAGV ICSAAHSWST PSPDTLPTIT LPASTVGSES SLALRLVNGG
510 520 530 540 550
DRCQGRVEVL YRGSWGTVCD DSWDTNDANV VCRQLGCGWA TSAPGNARFG
560 570 580 590 600
QGSGPIVLDD VRCSGHESYL WSCPHNGWLS HNCGHHEDAG VICSASQSQP
610 620 630 640 650
TPSPDTWPTS RASTAGSEST LALRLVNGGD RCRGRVEVLY QGSWGTVCDD
660 670 680 690 700
YWDTNDANVV CRQLGCGWAM SAPGNAQFGQ GSGPIVLDDV RCSGHESYLW
710 720 730 740 750
SCPHNGWLSH NCGHHEDAGV ICSAAQSQST PRPDTWLTTN LPALTVGSES
760 770 780 790 800
SLALRLVNGG DRCRGRVEVL YRGSWGTVCD DSWDTNDANV VCRQLGCGWA
810 820 830 840 850
MSAPGNARFG QGSGPIVLDD VRCSGNESYL WSCPHKGWLT HNCGHHEDAG
860 870 880 890 900
VICSATQINS TTTDWWHPTT TTTARPSSNC GGFLFYASGT FSSPSYPAYY
910 920 930 940 950
PNNAKCVWEI EVNSGYRINL GFSNLKLEAH HNCSFDYVEI FDGSLNSSLL
960 970 980 990 1000
LGKICNDTRQ IFTSSYNRMT IHFRSDISFQ NTGFLAWYNS FPSDATLRLV
1010 1020 1030 1040 1050
NLNSSYGLCA GRVEIYHGGT WGTVCDDSWT IQEAEVVCRQ LGCGRAVSAL
1060 1070 1080 1090 1100
GNAYFGSGSG PITLDDVECS GTESTLWQCR NRGWFSHNCN HREDAGVICS
1110 1120 1130 1140 1150
GNHLSTPAPF LNITRPNTDY SCGGFLSQPS GDFSSPFYPG NYPNNAKCVW
1160 1170 1180 1190 1200
DIEVQNNYRV TVIFRDVQLE GGCNYDYIEV FDGPYRSSPL IARVCDGARG
1210 1220 1230 1240 1250
SFTSSSNFMS IRFISDHSIT RRGFRAEYYS SPSNDSTNLL CLPNHMQASV
1260 1270 1280 1290 1300
SRSYLQSLGF SASDLVISTW NGYYECRPQI TPNLVIFTIP YSGCGTFKQA
1310 1320 1330 1340 1350
DNDTIDYSNF LTAAVSGGII KRRTDLRIHV SCRMLQNTWV DTMYIANDTI
1360 1370 1380 1390 1400
HVANNTIQVE EVQYGNFDVN ISFYTSSSFL YPVTSRPYYV DLNQDLYVQA
1410 1420 1430 1440 1450
EILHSDAVLT LFVDTCVASP YSNDFTSLTY DLIRSGCVRD DTYGPYSSPS
1460 1470 1480 1490 1500
LRIARFRFRA FHFLNRFPSV YLRCKMVVCR AYDPSSRCYR GCVLRSKRDV
1510 1520
GSYQEKVDVV LGPIQLQTPP RREEEPR
Note: No experimental confirmation available.
Show »Length:1,527
Mass (Da):166,501
<p>The checksum is a form of redundancy check that is calculated
from the sequence. It is useful for tracking sequence updates.</p>
<p>It should be noted that while, in theory, two different sequences could
have the same checksum value, the likelihood that this would happen
is extremely low.</p>
<p>However UniProtKB may contain entries with identical sequences in case
of multiple genes (paralogs).</p>
<p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64)
using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1.
The algorithm is described in the ISO 3309 standard.
</p>
<p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br />
<strong>Cyclic redundancy and other checksums</strong><br />
<a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p>
Checksum:iED984E0EF2736C69
Isoform 6 (identifier: Q9UGM3-6) [UniParc]FASTAAdd to basketAdded to basketShow »
The sequence of this isoform differs from the canonical sequence as follows:
1169-1169: M → MSAPGNARFG...CRQLGCGWAT
10 20 30 40 50
MGISTVILEM CLLWGQVLST GGWIPRTTDY ASLIPSEVPL DPTVAEGSPF
60 70 80 90 100
PSESTLESTV AEGSPISLES TLESTVAEGS LIPSESTLES TVAEGSDSGL
110 120 130 140 150
ALRLVNGDGR CQGRVEILYR GSWGTVCDDS WDTNDANVVC RQLGCGWAMS
160 170 180 190 200
APGNAWFGQG SGPIALDDVR CSGHESYLWS CPHNGWLSHN CGHGEDAGVI
210 220 230 240 250
CSAAQPQSTL RPESWPVRIS PPVPTEGSES SLALRLVNGG DRCRGRVEVL
260 270 280 290 300
YRGSWGTVCD DYWDTNDANV VCRQLGCGWA MSAPGNAQFG QGSGPIVLDD
310 320 330 340 350
VRCSGHESYL WSCPHNGWLT HNCGHSEDAG VICSAPQSRP TPSPDTWPTS
360 370 380 390 400
HASTAGPESS LALRLVNGGD RCQGRVEVLY RGSWGTVCDD SWDTSDANVV
410 420 430 440 450
CRQLGCGWAT SAPGNARFGQ GSGPIVLDDV RCSGYESYLW SCPHNGWLSH
460 470 480 490 500
NCQHSEDAGV ICSAAHSWST PSPDTLPTIT LPASTVGSES SLALRLVNGG
510 520 530 540 550
DRCQGRVEVL YRGSWGTVCD DSWDTNDANV VCRQLGCGWA MLAPGNARFG
560 570 580 590 600
QGSGPIVLDD VRCSGNESYL WSCPHNGWLS HNCGHSEDAG VICSGPESSL
610 620 630 640 650
ALRLVNGGDR CQGRVEVLYR GSWGTVCDDS WDTNDANVVC RQLGCGWATS
660 670 680 690 700
APGNARFGQG SGPIVLDDVR CSGHESYLWS CPNNGWLSHN CGHHEDAGVI
710 720 730 740 750
CSAAQSRSTP RPDTLSTITL PPSTVGSESS LTLRLVNGSD RCQGRVEVLY
760 770 780 790 800
RGSWGTVCDD SWDTNDANVV CRQLGCGWAT SAPGNARFGQ GSGPIVLDDV
810 820 830 840 850
RCSGHESYLW SCPHNGWLSH NCGHHEDAGV ICSVSQSRPT PSPDTWPTSH
860 870 880 890 900
ASTAGPESSL ALRLVNGGDR CQGRVEVLYR GSWGTVCDDS WDTSDANVVC
910 920 930 940 950
RQLGCGWATS APGNARFGQG SGPIVLDDVR CSGYESYLWS CPHNGWLSHN
960 970 980 990 1000
CQHSEDAGVI CSAAHSWSTP SPDTLPTITL PASTVGSESS LALRLVNGGD
1010 1020 1030 1040 1050
RCQGRVEVLY QGSWGTVCDD SWDTNDANVV CRQLGCGWAM SAPGNARFGQ
1060 1070 1080 1090 1100
GSGPIVLDDV RCSGHESYLW SCPHNGWLSH NCGHSEDAGV ICSASQSRPT
1110 1120 1130 1140 1150
PSPDTWPTSH ASTAGSESSL ALRLVNGGDR CQGRVEVLYR GSWGTVCDDY
1160 1170 1180 1190 1200
WDTNDANVVC RQLGCGWAMS APGNARFGQG SGPIVLDDVR CSGHESYLWS
1210 1220 1230 1240 1250
CPHNGWLSHN CGHHEDAGVI CSASQSQPTP SPDTWPTSHA STAGSESSLA
1260 1270 1280 1290 1300
LRLVNGGDRC QGRVEVLYRG SWGTVCDDYW DTNDANVVCR QLGCGWATSA
1310 1320 1330 1340 1350
PGNARFGQGS GPIVLDDVRC SGHESYLWSC PHNGWLSHNC GHHEDAGVIC
1360 1370 1380 1390 1400
SASQSQPTPS PDTWPTSHAS TAGSESSLAL RLVNGGDRCQ GRVEVLYRGS
1410 1420 1430 1440 1450
WGTVCDDYWD TNDANVVCRQ LGCGWATSAP GNARFGQGSG PIVLDDVRCS
1460 1470 1480 1490 1500
GHESYLWSCP HNGWLSHNCG HHEDAGVICS ASQSQPTPSP DTWPTSHAST
1510 1520 1530 1540 1550
AGSESSLALR LVNGGDRCQG RVEVLYRGSW GTVCDDYWDT NDANVVCRQL
1560 1570 1580 1590 1600
GCGWATSAPG NARFGQGSGP IVLDDVRCSG HESYLWSCPH NGWLSHNCGH
1610 1620 1630 1640 1650
HEDAGVICSA SQSQPTPSPD TWPTSRASTA GSESTLALRL VNGGDRCRGR
1660 1670 1680 1690 1700
VEVLYQGSWG TVCDDYWDTN DANVVCRQLG CGWAMSAPGN AQFGQGSGPI
1710 1720 1730 1740 1750
VLDDVRCSGH ESYLWSCPHN GWLSHNCGHH EDAGVICSAA QSQSTPRPDT
1760 1770 1780 1790 1800
WLTTNLPALT VGSESSLALR LVNGGDRCRG RVEVLYRGSW GTVCDDSWDT
1810 1820 1830 1840 1850
NDANVVCRQL GCGWAMSAPG NARFGQGSGP IVLDDVRCSG NESYLWSCPH
1860 1870 1880 1890 1900
KGWLTHNCGH HEDAGVICSA TQINSTTTDW WHPTTTTTAR PSSNCGGFLF
1910 1920 1930 1940 1950
YASGTFSSPS YPAYYPNNAK CVWEIEVNSG YRINLGFSNL KLEAHHNCSF
1960 1970 1980 1990 2000
DYVEIFDGSL NSSLLLGKIC NDTRQIFTSS YNRMTIHFRS DISFQNTGFL
2010 2020 2030 2040 2050
AWYNSFPSDA TLRLVNLNSS YGLCAGRVEI YHGGTWGTVC DDSWTIQEAE
2060 2070 2080 2090 2100
VVCRQLGCGR AVSALGNAYF GSGSGPITLD DVECSGTEST LWQCRNRGWF
2110 2120 2130 2140 2150
SHNCNHREDA GVICSGNHLS TPAPFLNITR PNTDYSCGGF LSQPSGDFSS
2160 2170 2180 2190 2200
PFYPGNYPNN AKCVWDIEVQ NNYRVTVIFR DVQLEGGCNY DYIEVFDGPY
2210 2220 2230 2240 2250
RSSPLIARVC DGARGSFTSS SNFMSIRFIS DHSITRRGFR AEYYSSPSND
2260 2270 2280 2290 2300
STNLLCLPNH MQASVSRSYL QSLGFSASDL VISTWNGYYE CRPQITPNLV
2310 2320 2330 2340 2350
IFTIPYSGCG TFKQADNDTI DYSNFLTAAV SGGIIKRRTD LRIHVSCRML
2360 2370 2380 2390 2400
QNTWVDTMYI ANDTIHVANN TIQVEEVQYG NFDVNISFYT SSSFLYPVTS
2410 2420 2430 2440 2450
RPYYVDLNQD LYVQAEILHS DAVLTLFVDT CVASPYSNDF TSLTYDLIRS
2460 2470 2480 2490 2500
GCVRDDTYGP YSSPSLRIAR FRFRAFHFLN RFPSVYLRCK MVVCRAYDPS
2510 2520 2530 2540
SRCYRGCVLR SKRDVGSYQE KVDVVLGPIQ LQTPPRREEE PR
Length:2,542
Mass (Da):274,465
<p>The checksum is a form of redundancy check that is calculated
from the sequence. It is useful for tracking sequence updates.</p>
<p>It should be noted that while, in theory, two different sequences could
have the same checksum value, the likelihood that this would happen
is extremely low.</p>
<p>However UniProtKB may contain entries with identical sequences in case
of multiple genes (paralogs).</p>
<p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64)
using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1.
The algorithm is described in the ISO 3309 standard.
</p>
<p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br />
<strong>Cyclic redundancy and other checksums</strong><br />
<a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p>
Checksum:iA6390E0D194E6A22
Isoform 7 (identifier: Q9UGM3-7) [UniParc]FASTAAdd to basketAdded to basketShow »
The sequence of this isoform differs from the canonical sequence as follows:
464-473: Missing.
1169-1169: M → MSAPGNARFG...CRQLGCGWAT
10 20 30 40 50
MGISTVILEM CLLWGQVLST GGWIPRTTDY ASLIPSEVPL DPTVAEGSPF
60 70 80 90 100
PSESTLESTV AEGSPISLES TLESTVAEGS LIPSESTLES TVAEGSDSGL
110 120 130 140 150
ALRLVNGDGR CQGRVEILYR GSWGTVCDDS WDTNDANVVC RQLGCGWAMS
160 170 180 190 200
APGNAWFGQG SGPIALDDVR CSGHESYLWS CPHNGWLSHN CGHGEDAGVI
210 220 230 240 250
CSAAQPQSTL RPESWPVRIS PPVPTEGSES SLALRLVNGG DRCRGRVEVL
260 270 280 290 300
YRGSWGTVCD DYWDTNDANV VCRQLGCGWA MSAPGNAQFG QGSGPIVLDD
310 320 330 340 350
VRCSGHESYL WSCPHNGWLT HNCGHSEDAG VICSAPQSRP TPSPDTWPTS
360 370 380 390 400
HASTAGPESS LALRLVNGGD RCQGRVEVLY RGSWGTVCDD SWDTSDANVV
410 420 430 440 450
CRQLGCGWAT SAPGNARFGQ GSGPIVLDDV RCSGYESYLW SCPHNGWLSH
460 470 480 490 500
NCQHSEDAGV ICSDTLPTIT LPASTVGSES SLALRLVNGG DRCQGRVEVL
510 520 530 540 550
YRGSWGTVCD DSWDTNDANV VCRQLGCGWA MLAPGNARFG QGSGPIVLDD
560 570 580 590 600
VRCSGNESYL WSCPHNGWLS HNCGHSEDAG VICSGPESSL ALRLVNGGDR
610 620 630 640 650
CQGRVEVLYR GSWGTVCDDS WDTNDANVVC RQLGCGWATS APGNARFGQG
660 670 680 690 700
SGPIVLDDVR CSGHESYLWS CPNNGWLSHN CGHHEDAGVI CSAAQSRSTP
710 720 730 740 750
RPDTLSTITL PPSTVGSESS LTLRLVNGSD RCQGRVEVLY RGSWGTVCDD
760 770 780 790 800
SWDTNDANVV CRQLGCGWAT SAPGNARFGQ GSGPIVLDDV RCSGHESYLW
810 820 830 840 850
SCPHNGWLSH NCGHHEDAGV ICSVSQSRPT PSPDTWPTSH ASTAGPESSL
860 870 880 890 900
ALRLVNGGDR CQGRVEVLYR GSWGTVCDDS WDTSDANVVC RQLGCGWATS
910 920 930 940 950
APGNARFGQG SGPIVLDDVR CSGYESYLWS CPHNGWLSHN CQHSEDAGVI
960 970 980 990 1000
CSAAHSWSTP SPDTLPTITL PASTVGSESS LALRLVNGGD RCQGRVEVLY
1010 1020 1030 1040 1050
QGSWGTVCDD SWDTNDANVV CRQLGCGWAM SAPGNARFGQ GSGPIVLDDV
1060 1070 1080 1090 1100
RCSGHESYLW SCPHNGWLSH NCGHSEDAGV ICSASQSRPT PSPDTWPTSH
1110 1120 1130 1140 1150
ASTAGSESSL ALRLVNGGDR CQGRVEVLYR GSWGTVCDDY WDTNDANVVC
1160 1170 1180 1190 1200
RQLGCGWAMS APGNARFGQG SGPIVLDDVR CSGHESYLWS CPHNGWLSHN
1210 1220 1230 1240 1250
CGHHEDAGVI CSASQSQPTP SPDTWPTSHA STAGSESSLA LRLVNGGDRC
1260 1270 1280 1290 1300
QGRVEVLYRG SWGTVCDDYW DTNDANVVCR QLGCGWATSA PGNARFGQGS
1310 1320 1330 1340 1350
GPIVLDDVRC SGHESYLWSC PHNGWLSHNC GHHEDAGVIC SASQSQPTPS
1360 1370 1380 1390 1400
PDTWPTSHAS TAGSESSLAL RLVNGGDRCQ GRVEVLYRGS WGTVCDDYWD
1410 1420 1430 1440 1450
TNDANVVCRQ LGCGWATSAP GNARFGQGSG PIVLDDVRCS GHESYLWSCP
1460 1470 1480 1490 1500
HNGWLSHNCG HHEDAGVICS ASQSQPTPSP DTWPTSHAST AGSESSLALR
1510 1520 1530 1540 1550
LVNGGDRCQG RVEVLYRGSW GTVCDDYWDT NDANVVCRQL GCGWATSAPG
1560 1570 1580 1590 1600
NARFGQGSGP IVLDDVRCSG HESYLWSCPH NGWLSHNCGH HEDAGVICSA
1610 1620 1630 1640 1650
SQSQPTPSPD TWPTSRASTA GSESTLALRL VNGGDRCRGR VEVLYQGSWG
1660 1670 1680 1690 1700
TVCDDYWDTN DANVVCRQLG CGWAMSAPGN AQFGQGSGPI VLDDVRCSGH
1710 1720 1730 1740 1750
ESYLWSCPHN GWLSHNCGHH EDAGVICSAA QSQSTPRPDT WLTTNLPALT
1760 1770 1780 1790 1800
VGSESSLALR LVNGGDRCRG RVEVLYRGSW GTVCDDSWDT NDANVVCRQL
1810 1820 1830 1840 1850
GCGWAMSAPG NARFGQGSGP IVLDDVRCSG NESYLWSCPH KGWLTHNCGH
1860 1870 1880 1890 1900
HEDAGVICSA TQINSTTTDW WHPTTTTTAR PSSNCGGFLF YASGTFSSPS
1910 1920 1930 1940 1950
YPAYYPNNAK CVWEIEVNSG YRINLGFSNL KLEAHHNCSF DYVEIFDGSL
1960 1970 1980 1990 2000
NSSLLLGKIC NDTRQIFTSS YNRMTIHFRS DISFQNTGFL AWYNSFPSDA
2010 2020 2030 2040 2050
TLRLVNLNSS YGLCAGRVEI YHGGTWGTVC DDSWTIQEAE VVCRQLGCGR
2060 2070 2080 2090 2100
AVSALGNAYF GSGSGPITLD DVECSGTEST LWQCRNRGWF SHNCNHREDA
2110 2120 2130 2140 2150
GVICSGNHLS TPAPFLNITR PNTDYSCGGF LSQPSGDFSS PFYPGNYPNN
2160 2170 2180 2190 2200
AKCVWDIEVQ NNYRVTVIFR DVQLEGGCNY DYIEVFDGPY RSSPLIARVC
2210 2220 2230 2240 2250
DGARGSFTSS SNFMSIRFIS DHSITRRGFR AEYYSSPSND STNLLCLPNH
2260 2270 2280 2290 2300
MQASVSRSYL QSLGFSASDL VISTWNGYYE CRPQITPNLV IFTIPYSGCG
2310 2320 2330 2340 2350
TFKQADNDTI DYSNFLTAAV SGGIIKRRTD LRIHVSCRML QNTWVDTMYI
2360 2370 2380 2390 2400
ANDTIHVANN TIQVEEVQYG NFDVNISFYT SSSFLYPVTS RPYYVDLNQD
2410 2420 2430 2440 2450
LYVQAEILHS DAVLTLFVDT CVASPYSNDF TSLTYDLIRS GCVRDDTYGP
2460 2470 2480 2490 2500
YSSPSLRIAR FRFRAFHFLN RFPSVYLRCK MVVCRAYDPS SRCYRGCVLR
2510 2520 2530
SKRDVGSYQE KVDVVLGPIQ LQTPPRREEE PR
Length:2,532
Mass (Da):273,443
<p>The checksum is a form of redundancy check that is calculated
from the sequence. It is useful for tracking sequence updates.</p>
<p>It should be noted that while, in theory, two different sequences could
have the same checksum value, the likelihood that this would happen
is extremely low.</p>
<p>However UniProtKB may contain entries with identical sequences in case
of multiple genes (paralogs).</p>
<p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64)
using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1.
The algorithm is described in the ISO 3309 standard.
</p>
<p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br />
<strong>Cyclic redundancy and other checksums</strong><br />
<a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p>
Checksum:i3E96E2D1F87EA45A
Isoform 8 (identifier: Q9UGM3-8) [UniParc]FASTAAdd to basketAdded to basketShow »
The sequence of this isoform differs from the canonical sequence as follows:
472-478: SPDTLPT → RPGERPR
479-971: Missing.
1099-1356: Missing.
10 20 30 40 50
MGISTVILEM CLLWGQVLST GGWIPRTTDY ASLIPSEVPL DPTVAEGSPF
60 70 80 90 100
PSESTLESTV AEGSPISLES TLESTVAEGS LIPSESTLES TVAEGSDSGL
110 120 130 140 150
ALRLVNGDGR CQGRVEILYR GSWGTVCDDS WDTNDANVVC RQLGCGWAMS
160 170 180 190 200
APGNAWFGQG SGPIALDDVR CSGHESYLWS CPHNGWLSHN CGHGEDAGVI
210 220 230 240 250
CSAAQPQSTL RPESWPVRIS PPVPTEGSES SLALRLVNGG DRCRGRVEVL
260 270 280 290 300
YRGSWGTVCD DYWDTNDANV VCRQLGCGWA MSAPGNAQFG QGSGPIVLDD
310 320 330 340 350
VRCSGHESYL WSCPHNGWLT HNCGHSEDAG VICSAPQSRP TPSPDTWPTS
360 370 380 390 400
HASTAGPESS LALRLVNGGD RCQGRVEVLY RGSWGTVCDD SWDTSDANVV
410 420 430 440 450
CRQLGCGWAT SAPGNARFGQ GSGPIVLDDV RCSGYESYLW SCPHNGWLSH
460 470 480 490 500
NCQHSEDAGV ICSAAHSWST PRPGERPRPD TLPTITLPAS TVGSESSLAL
510 520 530 540 550
RLVNGGDRCQ GRVEVLYQGS WGTVCDDSWD TNDANVVCRQ LGCGWAMSAP
560 570 580 590 600
GNARFGQGSG PIVLDDVRCS GHESYLWSCP HNGWLSHNCG HSEDAGVICS
610 620 630 640 650
ASQSRPTPSP DTWPTSHAST AGSESSLALR LVNGGDRCQG RVEVLYRGSW
660 670 680 690 700
GTVCDDYWDT NDANVVCRQL GCGWATSAPG NARFGQGSGP IVLDDVRCSG
710 720 730 740 750
HESYLWSCPH NGWLSHNCGH HEDAGVICSA SQSQPTPSPD TWPTSRASTA
760 770 780 790 800
GSESTLALRL VNGGDRCRGR VEVLYQGSWG TVCDDYWDTN DANVVCRQLG
810 820 830 840 850
CGWAMSAPGN AQFGQGSGPI VLDDVRCSGH ESYLWSCPHN GWLSHNCGHH
860 870 880 890 900
EDAGVICSAA QSQSTPRPDT WLTTNLPALT VGSESSLALR LVNGGDRCRG
910 920 930 940 950
RVEVLYRGSW GTVCDDSWDT NDANVVCRQL GCGWAMSAPG NARFGQGSGP
960 970 980 990 1000
IVLDDVRCSG NESYLWSCPH KGWLTHNCGH HEDAGVICSA TQINSTTTDW
1010 1020 1030 1040 1050
WHPTTTTTAR PSSNCGGFLF YASGTFSSPS YPAYYPNNAK CVWEIEVNSG
1060 1070 1080 1090 1100
YRINLGFSNL KLEAHHNCSF DYVEIFDGSL NSSLLLGKIC NDTRQIFTSS
1110 1120 1130 1140 1150
YNRMTIHFRS DISFQNTGFL AWYNSFPSDA TLRLVNLNSS YGLCAGRVEI
1160 1170 1180 1190 1200
YHGGTWGTVC DDSWTIQEAE VVCRQLGCGR AVSALGNAYF GSGSGPITLD
1210 1220 1230 1240 1250
DVECSGTEST LWQCRNRGWF SHNCNHREDA GVICSGNHLS TPAPFLNITR
1260 1270 1280 1290 1300
PNTDYSCGGF LSQPSGDFSS PFYPGNYPNN AKCVWDIEVQ NNYRVTVIFR
1310 1320 1330 1340 1350
DVQLEGGCNY DYIEVFDGPY RSSPLIARVC DGARGSFTSS SNFMSIRFIS
1360 1370 1380 1390 1400
DHSITRRGFR AEYYSSPSND STNLLCLPNH MQASVSRSYL QSLGFSASDL
1410 1420 1430 1440 1450
VISTWNGYYE CRPQITPNLV IFTIPYSGCG TFKQADNDTI DYSNFLTAAV
1460 1470 1480 1490 1500
SGGIIKRRTD LRIHVSCRML QNTWVDTMYI ANDTIHVANN TIQVEEVQYG
1510 1520 1530 1540 1550
NFDVNISFYT SSSFLYPVTS RPYYVDLNQD LYVQAEILHS DAVLTLFVDT
1560 1570 1580 1590 1600
CVASPYSNDF TSLTYDLIRS GCVRDDTYGP YSSPSLRIAR FRFRAFHFLN
1610 1620 1630 1640 1650
RFPSVYLRCK MVVCRAYDPS SRCYRGCVLR SKRDVGSYQE KVDVVLGPIQ
1660
LQTPPRREEE PR
Length:1,662
Mass (Da):180,973
<p>The checksum is a form of redundancy check that is calculated
from the sequence. It is useful for tracking sequence updates.</p>
<p>It should be noted that while, in theory, two different sequences could
have the same checksum value, the likelihood that this would happen
is extremely low.</p>
<p>However UniProtKB may contain entries with identical sequences in case
of multiple genes (paralogs).</p>
<p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64)
using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1.
The algorithm is described in the ISO 3309 standard.
</p>
<p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br />
<strong>Cyclic redundancy and other checksums</strong><br />
<a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p>
Checksum:iB9655F67233F6AE3
Isoform 5 (identifier: Q9UGM3-5) [UniParc]FASTAAdd to basketAdded to basket
The sequence of this isoform differs from the canonical sequence as follows:
1741-1761: ATQINSTTTDWWHPTTTTTAR → G
10 20 30 40 50
MGISTVILEM CLLWGQVLST GGWIPRTTDY ASLIPSEVPL DPTVAEGSPF
60 70 80 90 100
PSESTLESTV AEGSPISLES TLESTVAEGS LIPSESTLES TVAEGSDSGL
110 120 130 140 150
ALRLVNGDGR CQGRVEILYR GSWGTVCDDS WDTNDANVVC RQLGCGWAMS
160 170 180 190 200
APGNAWFGQG SGPIALDDVR CSGHESYLWS CPHNGWLSHN CGHGEDAGVI
210 220 230 240 250
CSAAQPQSTL RPESWPVRIS PPVPTEGSES SLALRLVNGG DRCRGRVEVL
260 270 280 290 300
YRGSWGTVCD DYWDTNDANV VCRQLGCGWA MSAPGNAQFG QGSGPIVLDD
310 320 330 340 350
VRCSGHESYL WSCPHNGWLT HNCGHSEDAG VICSAPQSRP TPSPDTWPTS
360 370 380 390 400
HASTAGPESS LALRLVNGGD RCQGRVEVLY RGSWGTVCDD SWDTSDANVV
410 420 430 440 450
CRQLGCGWAT SAPGNARFGQ GSGPIVLDDV RCSGYESYLW SCPHNGWLSH
460 470 480 490 500
NCQHSEDAGV ICSAAHSWST PSPDTLPTIT LPASTVGSES SLALRLVNGG
510 520 530 540 550
DRCQGRVEVL YRGSWGTVCD DSWDTNDANV VCRQLGCGWA MLAPGNARFG
560 570 580 590 600
QGSGPIVLDD VRCSGNESYL WSCPHNGWLS HNCGHSEDAG VICSGPESSL
610 620 630 640 650
ALRLVNGGDR CQGRVEVLYR GSWGTVCDDS WDTNDANVVC RQLGCGWATS
660 670 680 690 700
APGNARFGQG SGPIVLDDVR CSGHESYLWS CPNNGWLSHN CGHHEDAGVI
710 720 730 740 750
CSAAQSRSTP RPDTLSTITL PPSTVGSESS LTLRLVNGSD RCQGRVEVLY
760 770 780 790 800
RGSWGTVCDD SWDTNDANVV CRQLGCGWAT SAPGNARFGQ GSGPIVLDDV
810 820 830 840 850
RCSGHESYLW SCPHNGWLSH NCGHHEDAGV ICSVSQSRPT PSPDTWPTSH
860 870 880 890 900
ASTAGPESSL ALRLVNGGDR CQGRVEVLYR GSWGTVCDDS WDTSDANVVC
910 920 930 940 950
RQLGCGWATS APGNARFGQG SGPIVLDDVR CSGYESYLWS CPHNGWLSHN
960 970 980 990 1000
CQHSEDAGVI CSAAHSWSTP SPDTLPTITL PASTVGSESS LALRLVNGGD
1010 1020 1030 1040 1050
RCQGRVEVLY QGSWGTVCDD SWDTNDANVV CRQLGCGWAM SAPGNARFGQ
1060 1070 1080 1090 1100
GSGPIVLDDV RCSGHESYLW SCPHNGWLSH NCGHSEDAGV ICSASQSRPT
1110 1120 1130 1140 1150
PSPDTWPTSH ASTAGSESSL ALRLVNGGDR CQGRVEVLYR GSWGTVCDDY
1160 1170 1180 1190 1200
WDTNDANVVC RQLGCGWAMS APGNARFGQG SGPIVLDDVR CSGHESYLWS
1210 1220 1230 1240 1250
CPHNGWLSHN CGHHEDAGVI CSASQSQPTP SPDTWPTSHA STAGSESSLA
1260 1270 1280 1290 1300
LRLVNGGDRC QGRVEVLYRG SWGTVCDDYW DTNDANVVCR QLGCGWATSA
1310 1320 1330 1340 1350
PGNARFGQGS GPIVLDDVRC SGHESYLWSC PHNGWLSHNC GHHEDAGVIC
1360 1370 1380 1390 1400
SASQSQPTPS PDTWPTSHAS TAGSESSLAL RLVNGGDRCQ GRVEVLYRGS
1410 1420 1430 1440 1450
WGTVCDDYWD TNDANVVCRQ LGCGWATSAP GNARFGQGSG PIVLDDVRCS
1460 1470 1480 1490 1500
GHESYLWSCP HNGWLSHNCG HHEDAGVICS ASQSQPTPSP DTWPTSRAST
1510 1520 1530 1540 1550
AGSESTLALR LVNGGDRCRG RVEVLYQGSW GTVCDDYWDT NDANVVCRQL
1560 1570 1580 1590 1600
GCGWAMSAPG NAQFGQGSGP IVLDDVRCSG HESYLWSCPH NGWLSHNCGH
1610 1620 1630 1640 1650
HEDAGVICSA AQSQSTPRPD TWLTTNLPAL TVGSESSLAL RLVNGGDRCR
1660 1670 1680 1690 1700
GRVEVLYRGS WGTVCDDSWD TNDANVVCRQ LGCGWAMSAP GNARFGQGSG
1710 1720 1730 1740 1750
PIVLDDVRCS GNESYLWSCP HKGWLTHNCG HHEDAGVICS GPSSNCGGFL
1760 1770 1780 1790 1800
FYASGTFSSP SYPAYYPNNA KCVWEIEVNS GYRINLGFSN LKLEAHHNCS
1810 1820 1830 1840 1850
FDYVEIFDGS LNSSLLLGKI CNDTRQIFTS SYNRMTIHFR SDISFQNTGF
1860 1870 1880 1890 1900
LAWYNSFPSD ATLRLVNLNS SYGLCAGRVE IYHGGTWGTV CDDSWTIQEA
1910 1920 1930 1940 1950
EVVCRQLGCG RAVSALGNAY FGSGSGPITL DDVECSGTES TLWQCRNRGW
1960 1970 1980 1990 2000
FSHNCNHRED AGVICSGNHL STPAPFLNIT RPNTDYSCGG FLSQPSGDFS
2010 2020 2030 2040 2050
SPFYPGNYPN NAKCVWDIEV QNNYRVTVIF RDVQLEGGCN YDYIEVFDGP
2060 2070 2080 2090 2100
YRSSPLIARV CDGARGSFTS SSNFMSIRFI SDHSITRRGF RAEYYSSPSN
2110 2120 2130 2140 2150
DSTNLLCLPN HMQASVSRSY LQSLGFSASD LVISTWNGYY ECRPQITPNL
2160 2170 2180 2190 2200
VIFTIPYSGC GTFKQADNDT IDYSNFLTAA VSGGIIKRRT DLRIHVSCRM
2210 2220 2230 2240 2250
LQNTWVDTMY IANDTIHVAN NTIQVEEVQY GNFDVNISFY TSSSFLYPVT
2260 2270 2280 2290 2300
SRPYYVDLNQ DLYVQAEILH SDAVLTLFVD TCVASPYSND FTSLTYDLIR
2310 2320 2330 2340 2350
SGCVRDDTYG PYSSPSLRIA RFRFRAFHFL NRFPSVYLRC KMVVCRAYDP
2360 2370 2380 2390
SSRCYRGCVL RSKRDVGSYQ EKVDVVLGPI QLQTPPRREE EPR
Note: No experimental confirmation available.
Show »Length:2,393
Mass (Da):258,420
<p>The checksum is a form of redundancy check that is calculated
from the sequence. It is useful for tracking sequence updates.</p>
<p>It should be noted that while, in theory, two different sequences could
have the same checksum value, the likelihood that this would happen
is extremely low.</p>
<p>However UniProtKB may contain entries with identical sequences in case
of multiple genes (paralogs).</p>
<p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64)
using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1.
The algorithm is described in the ISO 3309 standard.
</p>
<p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br />
<strong>Cyclic redundancy and other checksums</strong><br />
<a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p>
Checksum:iD2AA22898581A701
Isoform 9 (identifier: Q9UGM3-9) [UniParc]FASTAAdd to basketAdded to basket
The sequence of this isoform differs from the canonical sequence as follows:
201-332: Missing.
344-1360: Missing.
1608-1738: Missing.
10 20 30 40 50
MGISTVILEM CLLWGQVLST GGWIPRTTDY ASLIPSEVPL DPTVAEGSPF
60 70 80 90 100
PSESTLESTV AEGSPISLES TLESTVAEGS LIPSESTLES TVAEGSDSGL
110 120 130 140 150
ALRLVNGDGR CQGRVEILYR GSWGTVCDDS WDTNDANVVC RQLGCGWAMS
160 170 180 190 200
APGNAWFGQG SGPIALDDVR CSGHESYLWS CPHNGWLSHN CGHGEDAGVI
210 220 230 240 250
CSAPQSRPTP SPDTWPTSHA STAGSESSLA LRLVNGGDRC QGRVEVLYRG
260 270 280 290 300
SWGTVCDDYW DTNDANVVCR QLGCGWATSA PGNARFGQGS GPIVLDDVRC
310 320 330 340 350
SGHESYLWSC PHNGWLSHNC GHHEDAGVIC SASQSQPTPS PDTWPTSRAS
360 370 380 390 400
TAGSESTLAL RLVNGGDRCR GRVEVLYQGS WGTVCDDYWD TNDANVVCRQ
410 420 430 440 450
LGCGWAMSAP GNAQFGQGSG PIVLDDVRCS GHESYLWSCP HNGWLSHNCG
460 470 480 490 500
HHEDAGVICS ATQINSTTTD WWHPTTTTTA RPSSNCGGFL FYASGTFSSP
510 520 530 540 550
SYPAYYPNNA KCVWEIEVNS GYRINLGFSN LKLEAHHNCS FDYVEIFDGS
560 570 580 590 600
LNSSLLLGKI CNDTRQIFTS SYNRMTIHFR SDISFQNTGF LAWYNSFPSD
610 620 630 640 650
ATLRLVNLNS SYGLCAGRVE IYHGGTWGTV CDDSWTIQEA EVVCRQLGCG
660 670 680 690 700
RAVSALGNAY FGSGSGPITL DDVECSGTES TLWQCRNRGW FSHNCNHRED
710 720 730 740 750
AGVICSGNHL STPAPFLNIT RPNTDYSCGG FLSQPSGDFS SPFYPGNYPN
760 770 780 790 800
NAKCVWDIEV QNNYRVTVIF RDVQLEGGCN YDYIEVFDGP YRSSPLIARV
810 820 830 840 850
CDGARGSFTS SSNFMSIRFI SDHSITRRGF RAEYYSSPSN DSTNLLCLPN
860 870 880 890 900
HMQASVSRSY LQSLGFSASD LVISTWNGYY ECRPQITPNL VIFTIPYSGC
910 920 930 940 950
GTFKQADNDT IDYSNFLTAA VSGGIIKRRT DLRIHVSCRM LQNTWVDTMY
960 970 980 990 1000
IANDTIHVAN NTIQVEEVQY GNFDVNISFY TSSSFLYPVT SRPYYVDLNQ
1010 1020 1030 1040 1050
DLYVQAEILH SDAVLTLFVD TCVASPYSND FTSLTYDLIR SGCVRDDTYG
1060 1070 1080 1090 1100
PYSSPSLRIA RFRFRAFHFL NRFPSVYLRC KMVVCRAYDP SSRCYRGCVL
1110 1120 1130
RSKRDVGSYQ EKVDVVLGPI QLQTPPRREE EPR
Note: No experimental confirmation available.
Show »Length:1,133
Mass (Da):124,452
<p>The checksum is a form of redundancy check that is calculated
from the sequence. It is useful for tracking sequence updates.</p>
<p>It should be noted that while, in theory, two different sequences could
have the same checksum value, the likelihood that this would happen
is extremely low.</p>
<p>However UniProtKB may contain entries with identical sequences in case
of multiple genes (paralogs).</p>
<p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64)
using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1.
The algorithm is described in the ISO 3309 standard.
</p>
<p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br />
<strong>Cyclic redundancy and other checksums</strong><br />
<a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p>
Checksum:i59ED2884BD6C86A5
Experimental Info
| Feature key | Position(s) | DescriptionActions | Graphical view | Length |
|---|---|---|---|---|
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 10 | M → V in CAC44122 (PubMed:11751412).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 13 | L → S in BAH14118 (PubMed:14702039).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 31 | A → T in AAI53300 (PubMed:15489334).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 42 | P → Q in AAD49696 (PubMed:10485905).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 42 | P → Q in AAI53300 (PubMed:15489334).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 74 | S → T in CAB56155 (PubMed:10485905).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 125 | T → A in CAB56155 (PubMed:10485905).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 188 | S → T in BAH14118 (PubMed:14702039).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 194 | G → S in BAH14118 (PubMed:14702039).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 468 | W → R in CAC44122 (PubMed:11751412).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 594 | S → SDTLPTTTLPASTV in CAB63941 (PubMed:10597221).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 603 | R → G in CAB63942 (PubMed:10597221).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 711 | R → G in CAC44122 (PubMed:11751412).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 902 | Q → R in CAB63942 (PubMed:10597221).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 1034 | L → P in CAA04019 (PubMed:9288095).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 1034 | L → P in AAD49696 (PubMed:10485905).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 1060 | V → A in CAB56155 (PubMed:10485905).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 1069 | L → P in CAA04019 (PubMed:9288095).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 1069 | L → P in AAD49696 (PubMed:10485905).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 1159 | V → A in CAB56155 (PubMed:10485905).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 1204 | N → D in CAB63942 (PubMed:10597221).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 1271 | S → P in CAB63942 (PubMed:10597221).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 1295 | G → S in CAC44122 (PubMed:11751412).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 1336 | L → F in CAC44122 (PubMed:11751412).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 1411 | T → I in AAI53300 (PubMed:15489334).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 1432 | N → S in CAB63942 (PubMed:10597221).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 1443 | V → A in CAB63942 (PubMed:10597221).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 1448 | R → H in AAI53300 (PubMed:15489334).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 1482 | S → F in CAB56155 (PubMed:10485905).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 1583 | S → P in CAB56155 (PubMed:10485905).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 1591 | N → K in BAH14118 (PubMed:14702039).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 1595 | S → T in BAH14118 (PubMed:14702039).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 1705 | D → G in CAB56155 (PubMed:10485905).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 1845 | R → G (PubMed:17974005).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 1909 | T → A in CAB56155 (PubMed:10485905).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 2004 – 2005 | TD → N in CAB56155 (PubMed:10485905).Curated | 2 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 2004 – 2005 | TD → N in CAI14494 (PubMed:15164054).Curated | 2 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 2196 | F → L in CAB56155 (PubMed:10485905).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 2380 | L → S in AAI53300 (PubMed:15489334).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 2405 | P → A in CAC44122 (PubMed:11751412).Curated | 1 |
<p>This subsection of the ‘Sequence’ section provides information on polymorphic variants. If the variant is associated with a disease state, the description of the latter can be found in the <a href="http://www.uniprot.org/manual/involvement_in_disease">'Involvement in disease'</a> subsection.<p><a href='/help/polymorphism' target='_top'>More...</a></p>Polymorphismi
The number of SRCR and SRCR-interspersed domains is polymorphic in a variety of tumors and may represent the major site of alterations in cancer.
Natural variant
| Feature key | Position(s) | DescriptionActions | Graphical view | Length |
|---|---|---|---|---|
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_024788 | 42 | P → T6 Publications <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
| 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_024789 | 52 | S → W2 Publications <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
| 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_024790 | 54 | S → L6 Publications <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
| 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_024791 | 60 | V → A4 Publications <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
| 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_024792 | 65 | P → L1 Publication <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
| 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_057981 | 162 | G → E in a glioma cell line. 1 Publication <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
| 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_044417 | 322 | N → D1 Publication <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
| 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_024793 | 337 | Q → L2 Publications <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
| 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_024794 | 357 | P → S2 Publications <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
| 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_024795 | 364 | R → G1 Publication <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
| 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_024796 | 420 | Q → H in a glioma sample; glioblastoma multiforme; somatic mutation. Corresponds to variant dbSNP:rs104894156Ensembl. | 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_057982 | 546 | N → S in a glioma cell line. 1 Publication <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
| 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_024797 | 607 | G → V in a glioma sample; pilocytic astrocytoma. | 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_024798 | 649 | T → M2 Publications <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
| 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_024799 | 656 | R → W. Corresponds to variant dbSNP:rs989419742Ensembl. | 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_052994 | 670 | R → C. Corresponds to variant dbSNP:rs2277237Ensembl. | 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_052995 | 719 | T → M. Corresponds to variant dbSNP:rs2277238Ensembl. | 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_024800 | 780 | T → M2 Publications <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
| 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_024801 | 856 | P → S4 Publications <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
| 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_024802 | 1084 | H → Y1 Publication <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
| 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_057983 | 1095 | S → P1 Publication <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
| 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_057984 | 1102 | S → T1 Publication <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
| 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_024803 | 1169 | M → T1 Publication <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
| 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_024804 | 1176 | R → W1 Publication <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
| 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_057985 | 1434 | R → W1 Publication <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
| 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_024805 | 1545 | V → M1 Publication <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
| 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_024806 | 1732 | H → S Requires 2 nucleotide substitutions. 2 Publications <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
| 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_044418 | 1860 | R → L. Corresponds to variant dbSNP:rs7099177Ensembl. | 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_024807 | 1961 | T → P1 Publication <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
| 1 | |
| <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_057986 | 2255 | V → M1 Publication <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
| 1 |
Alternative sequence
| Feature key | Position(s) | DescriptionActions | Graphical view | Length |
|---|---|---|---|---|
| <p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_053979 | 201 – 332 | Missing in isoform 9. 1 Publication <p>Manually curated information that is based on statements in scientific articles for which there is no experimental support.</p> <p><a href="/manual/evidences#ECO:0000303">More...</a></p> Manual assertion based on opinion ini
| 132 | |
| <p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_016846 | 337 – 835 | Missing in isoform 2. 1 Publication <p>Manually curated information that is based on statements in scientific articles for which there is no experimental support.</p> <p><a href="/manual/evidences#ECO:0000303">More...</a></p> Manual assertion based on opinion ini
| 499 | |
| <p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_053980 | 344 – 1360 | Missing in isoform 9. 1 Publication <p>Manually curated information that is based on statements in scientific articles for which there is no experimental support.</p> <p><a href="/manual/evidences#ECO:0000303">More...</a></p> Manual assertion based on opinion ini
| 1017 | |
| <p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_016847 | 464 – 473 | Missing in isoform 3 and isoform 7. 1 Publication <p>Manually curated information that is based on statements in scientific articles for which there is no experimental support.</p> <p><a href="/manual/evidences#ECO:0000303">More...</a></p> Manual assertion based on opinion ini
| 10 | |
| <p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_034653 | 472 – 478 | SPDTLPT → RPGERPR in isoform 8. 1 Publication <p>Manually curated information that is based on statements in scientific articles for which there is no experimental support.</p> <p><a href="/manual/evidences#ECO:0000303">More...</a></p> Manual assertion based on opinion ini
| 7 | |
| <p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_034654 | 479 – 971 | Missing in isoform 8. 1 Publication <p>Manually curated information that is based on statements in scientific articles for which there is no experimental support.</p> <p><a href="/manual/evidences#ECO:0000303">More...</a></p> Manual assertion based on opinion ini
| 493 | |
| <p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_016848 | 523 – 1408 | Missing in isoform 4. 1 Publication <p>Manually curated information that is based on statements in scientific articles for which there is no experimental support.</p> <p><a href="/manual/evidences#ECO:0000303">More...</a></p> Manual assertion based on opinion ini
| 886 | |
| <p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_034655 | 1099 – 1356 | Missing in isoform 8. 1 Publication <p>Manually curated information that is based on statements in scientific articles for which there is no experimental support.</p> <p><a href="/manual/evidences#ECO:0000303">More...</a></p> Manual assertion based on opinion ini
| 258 | |
| <p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_034656 | 1169 | M → MSAPGNARFGQGSGPIVLDD VRCSGHESYLWSCPHNGWLS HNCGHHEDAGVICSASQSQP TPSPDTWPTSHASTAGSESS LALRLVNGGDRCQGRVEVLY RGSWGTVCDDYWDTNDANVV CRQLGCGWAT in isoform 6 and isoform 7. Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_016849 | 1170 – 1298 | Missing in isoform 2. 1 Publication <p>Manually curated information that is based on statements in scientific articles for which there is no experimental support.</p> <p><a href="/manual/evidences#ECO:0000303">More...</a></p> Manual assertion based on opinion ini
| 129 | |
| <p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_053981 | 1608 – 1738 | Missing in isoform 9. 1 Publication <p>Manually curated information that is based on statements in scientific articles for which there is no experimental support.</p> <p><a href="/manual/evidences#ECO:0000303">More...</a></p> Manual assertion based on opinion ini
| 131 | |
| <p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_016850 | 1741 – 1761 | ATQIN…TTTAR → G in isoform 5. 1 Publication <p>Manually curated information that is based on statements in scientific articles for which there is no experimental support.</p> <p><a href="/manual/evidences#ECO:0000303">More...</a></p> Manual assertion based on opinion ini
| 21 |
Sequence databases
| Select the link destinations: EMBL nucleotide sequence database More...EMBLiGenBank nucleotide sequence database More...GenBankiDNA Data Bank of Japan; a nucleotide sequence database More...DDBJiLinks Updated | AJ000342 mRNA Translation: CAA04019.1 AF159456 mRNA Translation: AAD49696.1 AJ243212 mRNA Translation: CAB56155.1 AJ243211 Genomic DNA Translation: CAB63941.1 AJ243224 mRNA Translation: CAB63942.1 AB020851 Genomic DNA Translation: BAA78577.1 AJ297935 mRNA Translation: CAC44122.1 AK304149 mRNA Translation: BAH14118.1 AL603764 Genomic DNA Translation: CAI14487.1 AL603764 Genomic DNA Translation: CAI14488.1 AL603764 Genomic DNA Translation: CAI14489.1 AL603764 Genomic DNA Translation: CAI14490.1 AL603764 Genomic DNA Translation: CAI14491.1 AL603764 Genomic DNA Translation: CAI14492.1 AL603764 Genomic DNA Translation: CAI14493.1 AL603764 Genomic DNA Translation: CAI14494.1 AL603764 Genomic DNA Translation: CAI14495.1 AL603764 Genomic DNA Translation: CAI14496.1 BC153299 mRNA Translation: AAI53300.1 AB209691 mRNA Translation: BAD92928.1 BX640988 mRNA Translation: CAE45995.1 |
The Consensus CDS (CCDS) project More...CCDSi | CCDS44490.1 [Q9UGM3-1] CCDS44491.1 [Q9UGM3-2] CCDS44492.1 [Q9UGM3-3] |
Protein sequence database of the Protein Information Resource More...PIRi | A59386 |
NCBI Reference Sequences More...RefSeqi | NP_001307573.1, NM_001320644.1 NP_004397.2, NM_004406.2 [Q9UGM3-2] NP_015568.2, NM_007329.2 [Q9UGM3-1] NP_060049.2, NM_017579.2 [Q9UGM3-3] XP_011537690.1, XM_011539388.2 [Q9UGM3-6] XP_011537693.1, XM_011539391.2 [Q9UGM3-7] XP_011537707.1, XM_011539405.2 [Q9UGM3-1] |
UniGene gene-oriented nucleotide sequence clusters More...UniGenei | Hs.279611 |
Genome annotation databases
Ensembl eukaryotic genome annotation project More...Ensembli | ENST00000330163; ENSP00000327747; ENSG00000187908 [Q9UGM3-2] ENST00000338354; ENSP00000342210; ENSG00000187908 [Q9UGM3-1] ENST00000344338; ENSP00000343175; ENSG00000187908 [Q9UGM3-3] ENST00000368909; ENSP00000357905; ENSG00000187908 [Q9UGM3-1] ENST00000368955; ENSP00000357951; ENSG00000187908 [Q9UGM3-3] ENST00000368956; ENSP00000357952; ENSG00000187908 [Q9UGM3-2] ENST00000619379; ENSP00000484603; ENSG00000187908 [Q9UGM3-1] |
Database of genes from NCBI RefSeq genomes More...GeneIDi | 1755 |
KEGG: Kyoto Encyclopedia of Genes and Genomes More...KEGGi | hsa:1755 |
UCSC genome browser More...UCSCi | uc001lgk.1 human [Q9UGM3-1] |
<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Coding sequence diversityi
Alternative splicing, Polymorphism<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi
| Protein | Similar proteins | Species | Score | Length | |
|---|---|---|---|---|---|
| Q9UGM3 | UPI0005D01A45 | 2413 | |||
| UPI0005D01D39 | 2413 | ||||
| UPI000047021F | 2412 | ||||
| UPI0005CFF767 | 2411 | ||||
| UPI0005CFF89E | 2411 | ||||
| +4 | |||||
| Q9UGM3-2 | UPI0005D029AC | 1783 | |||
| UPI0007DBAEBC | 1778 | ||||
| UPI0005D02C7D | 1766 | ||||
| Q9UGM3-8 | 1662 | ||||
| Q9UGM3-4 | 1527 | ||||
| Q9UGM3-4 | UPI0005D029AC | 1783 | |||
| UPI0007DBAEBC | 1778 | ||||
| Q9UGM3-2 | 1785 | ||||
| UPI0005D02C7D | 1766 | ||||
| Q9UGM3-8 | 1662 | ||||
| Q9UGM3-6 | Deleted in malignant brain tumors 1 (Fragment) | 540 | |||
| UPI0005D00E39 | 2541 | ||||
| Q9UGM3-7 | 2532 | ||||
| UPI0005CFFCDC | 2532 | ||||
| UPI0005D0014B | 2532 | ||||
| +10 | |||||
| Q9UGM3-7 | Deleted in malignant brain tumors 1 (Fragment) | 540 | |||
| Q9UGM3-6 | 2542 | ||||
| UPI0005D00E39 | 2541 | ||||
| UPI0005CFFCDC | 2532 | ||||
| UPI0005D0014B | 2532 | ||||
| +10 | |||||
| Q9UGM3-8 | UPI0005D029AC | 1783 | |||
| UPI0007DBAEBC | 1778 | ||||
| Q9UGM3-2 | 1785 | ||||
| UPI0005D02C7D | 1766 | ||||
| Q9UGM3-4 | 1527 | ||||
| Protein | Similar proteins | Species | Score | Length | |
|---|---|---|---|---|---|
| Q9UGM3 | UPI0005D01A45 | 2413 | |||
| UPI000D09A301 | 2144 | ||||
| UPI00063CCFFE | 2345 | ||||
| UPI0006B3CA23 | 2155 | ||||
| UPI0005F3D691 | 2090 | ||||
| +42 | |||||
| Q9UGM3-2 | UPI0005D029AC | 1783 | |||
| UPI0007DBAEBC | 1778 | ||||
| Deleted in malignant brain tumors 1 | 2131 | ||||
| UPI00045E2156 | 1829 | ||||
| UPI0005F36040 | 1987 | ||||
| +12 | |||||
| Q9UGM3-4 | UPI0005D029AC | 1783 | |||
| UPI0007DBAEBC | 1778 | ||||
| Deleted in malignant brain tumors 1 | 2131 | ||||
| UPI00045E2156 | 1829 | ||||
| UPI0005F36040 | 1987 | ||||
| +12 | |||||
| Q9UGM3-8 | UPI0005D029AC | 1783 | |||
| UPI0007DBAEBC | 1778 | ||||
| Deleted in malignant brain tumors 1 | 2131 | ||||
| UPI00045E2156 | 1829 | ||||
| UPI0005F36040 | 1987 | ||||
| +12 | |||||
| Q9UGM3-9 | UPI0007663107 | 981 | |||
| Deleted in malignant brain tumors 1 | 1025 | ||||
| Uncharacterized protein | 1210 | ||||
| UPI0004D07D4D | 1152 | ||||
| Deleted in malignant brain tumors 1 protein | 1187 | ||||
| +6 | |||||
<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi
<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi
| Atlas of Genetics and Cytogenetics in Oncology and Haematology |
Sequence databases
| Select the link destinations: EMBL nucleotide sequence database More...EMBLiGenBank nucleotide sequence database More...GenBankiDNA Data Bank of Japan; a nucleotide sequence database More...DDBJiLinks Updated | AJ000342 mRNA Translation: CAA04019.1 AF159456 mRNA Translation: AAD49696.1 AJ243212 mRNA Translation: CAB56155.1 AJ243211 Genomic DNA Translation: CAB63941.1 AJ243224 mRNA Translation: CAB63942.1 AB020851 Genomic DNA Translation: BAA78577.1 AJ297935 mRNA Translation: CAC44122.1 AK304149 mRNA Translation: BAH14118.1 AL603764 Genomic DNA Translation: CAI14487.1 AL603764 Genomic DNA Translation: CAI14488.1 AL603764 Genomic DNA Translation: CAI14489.1 AL603764 Genomic DNA Translation: CAI14490.1 AL603764 Genomic DNA Translation: CAI14491.1 AL603764 Genomic DNA Translation: CAI14492.1 AL603764 Genomic DNA Translation: CAI14493.1 AL603764 Genomic DNA Translation: CAI14494.1 AL603764 Genomic DNA Translation: CAI14495.1 AL603764 Genomic DNA Translation: CAI14496.1 BC153299 mRNA Translation: AAI53300.1 AB209691 mRNA Translation: BAD92928.1 BX640988 mRNA Translation: CAE45995.1 |
The Consensus CDS (CCDS) project More...CCDSi | CCDS44490.1 [Q9UGM3-1] CCDS44491.1 [Q9UGM3-2] CCDS44492.1 [Q9UGM3-3] |
Protein sequence database of the Protein Information Resource More...PIRi | A59386 |
NCBI Reference Sequences More...RefSeqi | NP_001307573.1, NM_001320644.1 NP_004397.2, NM_004406.2 [Q9UGM3-2] NP_015568.2, NM_007329.2 [Q9UGM3-1] NP_060049.2, NM_017579.2 [Q9UGM3-3] XP_011537690.1, XM_011539388.2 [Q9UGM3-6] XP_011537693.1, XM_011539391.2 [Q9UGM3-7] XP_011537707.1, XM_011539405.2 [Q9UGM3-1] |
UniGene gene-oriented nucleotide sequence clusters More...UniGenei | Hs.279611 |
3D structure databases
Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase More...ProteinModelPortali | Q9UGM3 |
SWISS-MODEL Repository - a database of annotated 3D protein structure models More...SMRi | Q9UGM3 |
Database of comparative protein structure models More...ModBasei | Search... |
MobiDB: a database of protein disorder and mobility annotations More...MobiDBi | Search... |
Protein-protein interaction databases
The Biological General Repository for Interaction Datasets (BioGrid) More...BioGridi | 108095, 17 interactors |
Database of interacting proteins More...DIPi | DIP-50763N |
Protein interaction database and analysis system More...IntActi | Q9UGM3, 7 interactors |
STRING: functional protein association networks More...STRINGi | 9606.ENSP00000357905 |
PTM databases
iPTMnet integrated resource for PTMs in systems biology context More...iPTMneti | Q9UGM3 |
Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat. More...PhosphoSitePlusi | Q9UGM3 |
Polymorphism and mutation databases
BioMuta curated single-nucleotide variation and disease association database More...BioMutai | DMBT1 |
Domain mapping of disease mutations (DMDM) More...DMDMi | 85687556 |
Proteomic databases
PaxDb, a database of protein abundance averages across all three domains of life More...PaxDbi | Q9UGM3 |
PeptideAtlas More...PeptideAtlasi | Q9UGM3 |
PRoteomics IDEntifications database More...PRIDEi | Q9UGM3 |
Protocols and materials databases
The DNASU plasmid repository More...DNASUi | 1755 |
| Structural Biology Knowledgebase | Search... |
Genome annotation databases
Ensembl eukaryotic genome annotation project More...Ensembli | ENST00000330163; ENSP00000327747; ENSG00000187908 [Q9UGM3-2] ENST00000338354; ENSP00000342210; ENSG00000187908 [Q9UGM3-1] ENST00000344338; ENSP00000343175; ENSG00000187908 [Q9UGM3-3] ENST00000368909; ENSP00000357905; ENSG00000187908 [Q9UGM3-1] ENST00000368955; ENSP00000357951; ENSG00000187908 [Q9UGM3-3] ENST00000368956; ENSP00000357952; ENSG00000187908 [Q9UGM3-2] ENST00000619379; ENSP00000484603; ENSG00000187908 [Q9UGM3-1] |
Database of genes from NCBI RefSeq genomes More...GeneIDi | 1755 |
KEGG: Kyoto Encyclopedia of Genes and Genomes More...KEGGi | hsa:1755 |
UCSC genome browser More...UCSCi | uc001lgk.1 human [Q9UGM3-1] |
Organism-specific databases
Comparative Toxicogenomics Database More...CTDi | 1755 |
DisGeNET More...DisGeNETi | 1755 |
Eukaryotic Pathogen Database Resources More...EuPathDBi | HostDB:ENSG00000187908.15 |
GeneCards: human genes, protein and diseases More...GeneCardsi | DMBT1 |
H-Invitational Database, human transcriptome db More...H-InvDBi | HIX0026114 |
Human Gene Nomenclature Database More...HGNCi | HGNC:2926 DMBT1 |
Human Protein Atlas More...HPAi | HPA040778 |
Online Mendelian Inheritance in Man (OMIM) More...MIMi | 137800 phenotype 601969 gene |
neXtProt; the human protein knowledge platform More...neXtProti | NX_Q9UGM3 |
Open Targets More...OpenTargetsi | ENSG00000187908 |
The Pharmacogenetics and Pharmacogenomics Knowledge Base More...PharmGKBi | PA27376 |
GenAtlas: human gene database More...GenAtlasi | Search... |
Phylogenomic databases
evolutionary genealogy of genes: Non-supervised Orthologous Groups More...eggNOGi | ENOG410IHBC Eukaryota ENOG410XQVR LUCA |
Ensembl GeneTree More...GeneTreei | ENSGT00900000140803 |
The HOVERGEN Database of Homologous Vertebrate Genes More...HOVERGENi | HBG060122 |
InParanoid: Eukaryotic Ortholog Groups More...InParanoidi | Q9UGM3 |
KEGG Orthology (KO) More...KOi | K13912 |
Identification of Orthologs from Complete Genome Data More...OMAi | NTHNCGH |
Database of Orthologous Groups More...OrthoDBi | EOG091G0DF7 |
Database for complete collections of gene phylogenies More...PhylomeDBi | Q9UGM3 |
TreeFam database of animal gene trees More...TreeFami | TF329295 |
Enzyme and pathway databases
Reactome - a knowledgebase of biological pathways and processes More...Reactomei | R-HSA-5683826 Surfactant metabolism |
Miscellaneous databases
ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data More...ChiTaRSi | DMBT1 human |
The Gene Wiki collection of pages on human genes and proteins More...GeneWikii | DMBT1 |
Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens More...GenomeRNAii | 1755 |
Protein Ontology More...PROi | PR:Q9UGM3 |
The Stanford Online Universal Resource for Clones and ESTs More...SOURCEi | Search... |
Gene expression databases
Bgee dataBase for Gene Expression Evolution More...Bgeei | ENSG00000187908 |
Genevisible search portal to normalized and curated expression data from Genevestigator More...Genevisiblei | Q9UGM3 HS |
Family and domain databases
Conserved Domains Database More...CDDi | cd00041 CUB, 2 hits |
Gene3D Structural and Functional Annotation of Protein Families More...Gene3Di | 2.60.120.290, 2 hits 3.10.250.10, 14 hits |
Integrated resource of protein families, domains and functional sites More...InterProi | View protein in InterPro IPR000859 CUB_dom IPR035914 Sperma_CUB_dom_sf IPR001190 SRCR IPR017448 SRCR-like_dom IPR036772 SRCR-like_dom_sf IPR001507 ZP_dom IPR017977 ZP_dom_CS |
Pfam protein domain database More...Pfami | View protein in Pfam PF00431 CUB, 2 hits PF00530 SRCR, 14 hits PF00100 Zona_pellucida, 1 hit |
Protein Motif fingerprint database; a protein domain database More...PRINTSi | PR00258 SPERACTRCPTR |
Simple Modular Architecture Research Tool; a protein domain database More...SMARTi | View protein in SMART SM00042 CUB, 2 hits SM00202 SR, 14 hits SM00241 ZP, 1 hit |
Superfamily database of structural and functional annotation More...SUPFAMi | SSF49854 SSF49854, 2 hits SSF56487 SSF56487, 14 hits |
PROSITE; a protein domain and family database More...PROSITEi | View protein in PROSITE PS01180 CUB, 2 hits PS00420 SRCR_1, 13 hits PS50287 SRCR_2, 14 hits PS00682 ZP_1, 1 hit PS51034 ZP_2, 1 hit |
ProtoNet; Automatic hierarchical classification of proteins More...ProtoNeti | Search... |
<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi
| <p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry namei | DMBT1_HUMAN | |
| <p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>Accessioni | Q9UGM3Primary (citable) accession number: Q9UGM3 Secondary accession number(s): A6NDG4 , A6NDJ5, A8E4R5, B1ARE7, B1ARE8, B1ARE9, B1ARF0, B7Z8Y2, F8WEF7, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9 | |
| <p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 10, 2006 |
| Last sequence update: | January 10, 2006 | |
| Last modified: | May 23, 2018 | |
| This is version 163 of the entry and version 2 of the sequence. See complete history. | ||
| <p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
| Annotation program | Chordata Protein Annotation Program | |
| Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. | |
<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi
<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi
Complete proteome, Direct protein sequencing, Reference proteomeDocuments
- Human chromosome 10
Human chromosome 10: entries, gene names and cross-references to MIM - Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations - Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families
