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Protein

Cysteine-rich C-terminal protein 1

Gene

CRCT1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Cysteine-rich C-terminal protein 1
Alternative name(s):
Protein NICE-1
Gene namesi
Name:CRCT1
Synonyms:C1orf42, NICE1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000169509.5.
HGNCiHGNC:29875. CRCT1.

Pathology & Biotechi

Organism-specific databases

DisGeNETi54544.
OpenTargetsiENSG00000169509.
PharmGKBiPA162382812.

Polymorphism and mutation databases

BioMutaiCRCT1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000968121 – 99Cysteine-rich C-terminal protein 1Add BLAST99

Proteomic databases

PaxDbiQ9UGL9.
PeptideAtlasiQ9UGL9.
PRIDEiQ9UGL9.

Expressioni

Gene expression databases

BgeeiENSG00000169509.
CleanExiHS_CRCT1.
GenevisibleiQ9UGL9. HS.

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi120031. 21 interactors.
IntActiQ9UGL9. 52 interactors.
MINTiMINT-1368320.
STRINGi9606.ENSP00000357779.

Structurei

3D structure databases

ProteinModelPortaliQ9UGL9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi39 – 99Cys-richAdd BLAST61

Phylogenomic databases

GeneTreeiENSGT00730000113097.
HOVERGENiHBG094547.
OMAiTGCCCFP.

Family and domain databases

InterProiView protein in InterPro
IPR031698. NICE-1.
PfamiView protein in Pfam
PF15845. NICE-1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9UGL9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSQQSAVSA KGFSKGSSQG PAPCPAPAPT PAPASSSSCC GSGRGCCGDS
60 70 80 90
GCCGSSSTSC CCFPRRRRRQ RSSGCCCCGG GSQRSQRSNN RSSGCCSGC
Length:99
Mass (Da):9,736
Last modified:May 1, 2000 - v1
Checksum:iB522D8E206305FDB
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_05090696C → Y. Corresponds to variant dbSNP:rs16834168Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ243662 mRNA. Translation: CAB65093.1.
CR457218 mRNA. Translation: CAG33499.1.
AL135842 Genomic DNA. No translation available.
CH471121 Genomic DNA. Translation: EAW53379.1.
BC119710 mRNA. Translation: AAI19711.1.
CCDSiCCDS1012.1.
RefSeqiNP_061933.1. NM_019060.2.
XP_011507958.1. XM_011509656.2.
UniGeneiHs.110196.

Genome annotation databases

EnsembliENST00000368790; ENSP00000357779; ENSG00000169509.
GeneIDi54544.
KEGGihsa:54544.
UCSCiuc001ezz.4. human.

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiCRCT1_HUMAN
AccessioniPrimary (citable) accession number: Q9UGL9
Secondary accession number(s): A4QN00, Q6IAD7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 2000
Last modified: September 27, 2017
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot